Malignant endometrial polyps in postmenopausal breast cancer tamoxifen-treated patients.

abstract：BACKGROUND:Ovarian tumors in the pediatric population are most likely to be of germ cell origin. However, serous tumors have also been reported in adolescent patients. CASE:A 14-year-old girl was diagnosed with stage IIIc low-grade ovarian cancer. Her serum CA-125 was elevated preoperatively and was a marker for recur...

journal_title：Gynecologic oncology

authors： Parker LP,Ramirez PT,Broaddus R,Sightler S,Wolf JK

更新日期：2001-01-01 00:00:00

abstract：OBJECTIVE:To estimate the likelihood of occult cancer diagnosis at prophylactic oophorectomy in BRCA1 and BRCA2 carriers in different age groups and to determine the histopathology of these lesions. METHODS:We describe a series of 159 female BRCA1 or BRCA2 carriers who underwent prophylactic oophorectomy at the Univer...

journal_title：Gynecologic oncology

authors： Finch A,Shaw P,Rosen B,Murphy J,Narod SA,Colgan TJ

更新日期：2006-01-01 00:00:00

abstract：OBJECTIVE:The purpose of this phase II study was to evaluate on an intent-to-treat basis the activity and toxicity of single-agent vinorelbine (VRL) as second-line chemotherapy of patients with platinum-resistant ovarian cancer. Platinum-resistant disease was defined as disease refractory to or relapsing within 12 mont...

journal_title：Gynecologic oncology

authors： Sørensen P,Høyer M,Jakobsen A,Malmström H,Havsteen H,Bertelsen K

更新日期：2001-04-01 00:00:00

abstract：OBJECTIVES:Abnormalities in the control of cell proliferation and apoptosis have been suggested to contribute to the development and progression of neoplasia. There are at least two pathways that activate apoptosis. The first is a mitochondria-dependent route governed by bcl-2 family proteins. The second is a parallel ...

journal_title：Gynecologic oncology

authors： Atasoy P,Bozdoğan O,Erekul S,Bozdoğan N,Bayram M

更新日期：2003-11-01 00:00:00

abstract：OBJECTIVE:The long-term survival of patients with epithelial ovarian cancer is limited by the emergence of tumor cells that are resistant to chemotherapy. We hypothesized that expression of Bcl-x(L), a homologue of Bcl-2 that confers protection from chemotherapy-induced apoptosis, may be predictive of patients' clinica...

journal_title：Gynecologic oncology

authors： Williams J,Lucas PC,Griffith KA,Choi M,Fogoros S,Hu YY,Liu JR

更新日期：2005-02-01 00:00:00

abstract：:The role of elective lymphadenectomy in the treatment of patients with early-stage malignancies, although still commonly performed, remains a matter of controversy. This issue is important in the management of cancers and raises questions about the biologic interpretation of their natural history and about motives for...

journal_title：Gynecologic oncology

authors： Santin AD,Parham GP

更新日期：1998-01-01 00:00:00

abstract：:Malignant diseases have been shown to cause hypercoagulable states. Elevated prothrombin fragment F 1 + 2 plasma levels occur, when prothrombin is converted into thrombin by factor Xa. In order to evaluate the role of prothrombin fragment F 1 + 2 as an indicator for hemostatic disorders in patients with gynecologic ma...

journal_title：Gynecologic oncology

authors： Hanzal E,Tatra G

更新日期：1993-06-01 00:00:00

abstract：:Two patients with resistant gestational choriocarcinoma were treated w with Taxol after extensive prior chemotherapy including EMACO and platinum-based salvage chemotherapy. Both patients showed significant responses to Taxol. One patient relapsed in the brain and liver after treatment and died. Taxol was combined wit...

journal_title：Gynecologic oncology

authors： Jones WB,Schneider J,Shapiro F,Lewis JL Jr

更新日期：1996-04-01 00:00:00

abstract：OBJECTIVE:The hepatocyte growth factor (HGF) receptor c-Met plays an important role in tumor dissemination by activating mitogenic signaling pathways. The goal of this study was to investigate immunohistochemical (IHC) staining patterns of HGF and c-Met in endometrioid endometrial cancer (EC) and uterine serous cancer ...

journal_title：Gynecologic oncology

authors： Bishop EA,Lengyel ER,Yamada SD,Montag A,Temkin SM

更新日期：2011-04-01 00:00:00

abstract：:The effect of two beta-adrenergic stimulating agents on bladder and urethral function was assessed in 16 patients 3 weeks after radical hysterectomy for carcinoma of the cervix. Urodynamic evaluation was performed before and after inhalation of metaproterenol by metered dose inhaler in 10 patients and injection of 0.2...

journal_title：Gynecologic oncology

authors： Kerr-Wilson RH,Orr JW Jr,Shingleton HM,Hatch KD,Trammel MW

更新日期：1986-03-01 00:00:00

abstract：OBJECTIVE:Although the antiproliferative and differentiating properties of vitamin D have been demonstrated, its effects on cancer cells are variable. Little is known about vitamin D receptor (VDR) levels in patients with ovarian cancer. In this population we sought to determine correlations between VDR expression, cli...

journal_title：Gynecologic oncology

authors： Silvagno F,Poma CB,Realmuto C,Ravarino N,Ramella A,Santoro N,D'Amelio P,Fuso L,Pescarmona G,Zola P

更新日期：2010-10-01 00:00:00

abstract：:The usefulness of percutaneous endoscopic gastrostomy (PEG) for decompression in patients with unresolving intestinal obstruction by gynecological malignancy is examined. Between April 1993 and August 1995, 34 consecutive patients with small-bowel obstruction by gynecological cancer, heavily pretreated with surgery an...

journal_title：Gynecologic oncology

authors： Campagnutta E,Cannizzaro R,Gallo A,Zarrelli A,Valentini M,De Cicco M,Scarabelli C

更新日期：1996-07-01 00:00:00

abstract：:Homeobox (HOX) genes are a family of transcription factors that are essential regulators of development. HOX genes play important roles in normal reproductive physiology, as well as in the development and progression of serous carcinomas, the predominant and most aggressive subtype of epithelial ovarian cancer (EOC). ...

journal_title：Gynecologic oncology

authors： Miller KR,Patel JN,Ganapathi MK,Tait DL,Ganapathi RN

更新日期：2016-06-01 00:00:00

abstract：OBJECTIVE:The aim of this study is to evaluate the clinical characteristics of clear cell carcinoma of the ovary. METHODS:Between 1986 and 1996, 45 patients with clear cell carcinoma of the ovary were identified by scanning the medical records department and the tumor registry at our institution. RESULTS:Median age w...

journal_title：Gynecologic oncology

authors： Behbakht K,Randall TC,Benjamin I,Morgan MA,King S,Rubin SC

更新日期：1998-08-01 00:00:00

abstract：OBJECTIVE:To examine the DNA methyltransferase (DNMT) mRNA and protein levels in endometrioid and serous cancers and to study the relationship between DNA methyltransferase expression and endometrial cancer development. METHODS:Normal endometrium, Grade I and Grade III endometrioid carcinoma tissues and cell lines, as...

journal_title：Gynecologic oncology

authors： Xiong Y,Dowdy SC,Xue A,Shujuan J,Eberhardt NL,Podratz KC,Jiang SW

更新日期：2005-03-01 00:00:00

abstract：OBJECTIVE:Management of locally advanced cervical cancer consists primarily of combination external and internal radiation. In order to investigate the impact of intracavitary brachytherapy versus interstitial brachytherapy on local tumor control, survival, and complications, we retrospectively reviewed the concomitant...

journal_title：Gynecologic oncology

authors： Monk BJ,Tewari K,Burger RA,Johnson MT,Montz FJ,Berman ML

更新日期：1997-12-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to study the combination of intraperitoneal alpha-interferon and cisplatin administered second-line in an alternating sequence in small volume residual epithelial ovarian cancer after second-look surgery and the activity of this combination based on prior response to first-line plati...

journal_title：Gynecologic oncology

authors： Berek JS,Markman M,Blessing JA,Kucera PR,Nelson BE,Anderson B,Hanjani P

更新日期：1999-07-01 00:00:00

abstract：OBJECTIVE:To evaluate the long-term outcomes of young early stage cervical cancer patients wishing to preserve their childbearing potential. METHODS:Data of young (aged <40 years) patients with early stage cervical cancer were prospectively collected. All patients with stage IA2, IB1 and IB2 cervical cancer were inclu...

journal_title：Gynecologic oncology

authors： Bogani G,Chiappa V,Vinti D,Somigliana E,Filippi F,Murru G,Murgia F,Martinelli F,Ditto A,Raspagliesi F

更新日期：2019-07-01 00:00:00

abstract：OBJECTIVE:To examine the effect of postsurgical surveillance on survival of patients with FIGO stage I/II endometrial adenocarcinoma. METHODS:We examined the records of 354 patients who underwent primary surgical therapy for FIGO stage I/II endometrial adenocarcinoma. In patients who developed recurrent disease, we de...

journal_title：Gynecologic oncology

authors： Berchuck A,Anspach C,Evans AC,Soper JT,Rodriguez GC,Dodge R,Robboy S,Clarke-Pearson DL

更新日期：1995-10-01 00:00:00

abstract：OBJECTIVE:The objective of this study is to compare survival of Asian (AS), American Indian/Alaskan Native (AI/AN) and non-Hispanic white (NHW) women with endometrial adenocarcinoma (EC). METHODS:Patients with EC were identified from the Surveillance, Epidemiology, and End Results program from 1988 to 2009. Kaplan-Mei...

journal_title：Gynecologic oncology

authors： Mahdi H,Schlick CJ,Kowk LL,Moslemi-Kebria M,Michener C

更新日期：2014-02-01 00:00:00

abstract：OBJECTIVE:The aim of this study is to develop a risk-scoring system for predicting lymph node and distant metastasis in endometrial carcinoma. METHODS:A total of 1166 patients, treated at a single institution between 1-2007 and 12-2013, were included in the study. The association of stage IIIC-IV disease with demograp...

journal_title：Gynecologic oncology

authors： Tuomi T,Pasanen A,Luomaranta A,Leminen A,Bützow R,Loukovaara M

更新日期：2015-04-01 00:00:00

abstract：:The first case report of a 58-year-old woman with two different primary carcinoid tumors is presented. The bronchial carcinoid exhibited a mosaic pattern, whereas the ovarian tumor showed both insular and trabecular patterns. No teratomatous component was observed in the ovary. Both tumors presented an argyrophil reac...

journal_title：Gynecologic oncology

authors： Sorbe B,Valentin K,Wilander E

更新日期：1986-11-01 00:00:00

abstract：OBJECTIVE:Debate continues about optimal management of patients with node-positive stage I cervical cancer. Our objective was to determine if patient outcomes are affected by radical hysterectomy in the modern era of adjuvant chemoradiation. METHODS:Cervical cancer patients diagnosed from 2000 to 2008 were identified....

journal_title：Gynecologic oncology

authors： Ziebarth AJ,Smith H,Killian ME,Nguyen NA,Durst JK,Subramaniam A,Kim KH,Leath CA 3rd,Straughn JM Jr,Alvarez RD

更新日期：2012-07-01 00:00:00

abstract：OBJECTIVE:The first-line chemotherapy for ovarian cancer is based on a combination of platinum and taxane. To date, no reliable predictive biomarker has been recognized that is capable of identifying patients with pre-existing resistance to these agents. Here, we have established an integrated database and identified t...

journal_title：Gynecologic oncology

authors： Fekete JT,Ősz Á,Pete I,Nagy GR,Vereczkey I,Győrffy B

更新日期：2020-03-01 00:00:00

abstract：OBJECTIVE:The concept of "platinum sensitivity" has been widely applied in the management of recurrent ovarian cancer. This study aimed to evaluate the applicability of this concept to recurrent endometrial cancer. PATIENTS AND METHODS:In this multicenter retrospective cohort study, the clinical data of patients with ...

journal_title：Gynecologic oncology

authors： Nagao S,Nishio S,Michimae H,Tanabe H,Okada S,Otsuki T,Tanioka M,Fujiwara K,Suzuki M,Kigawa J

更新日期：2013-12-01 00:00:00

abstract：OBJECTIVE:The ABC transporter MRP2 (ABCC2) can mediate cisplatin efflux, and over-expression of MRP2 has been associated with cisplatin resistance in cancer cell lines. The aim of this study was to determine the role of MRP2 in modulating cisplatin cytotoxicity in normal cells as well as the relationship between MRP2 e...

journal_title：Gynecologic oncology

authors： Guminski AD,Balleine RL,Chiew YE,Webster LR,Tapner M,Farrell GC,Harnett PR,Defazio A

更新日期：2006-02-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate directly the utility of Fourier transform infrared microscopy (FTIR-MC) in detecting cervical precancer by comparison with the pathological examination of biopsy tissue. METHODS:Cervical biopsy specimens were obtained from the outpatient department at Kaohsiung Municipal...

journal_title：Gynecologic oncology

authors： Chang JI,Huang YB,Wu PC,Chen CC,Huang SC,Tsai YH

更新日期：2003-12-01 00:00:00

abstract：OBJECTIVES:To report the intermediate-term results of trans-abdominal ultrasound (TAUS)-guided brachytherapy in cervical cancer. MATERIALS AND METHODS:Ninety-two patients with cervical cancer (stage IB-IVA, according to FIGO staging), were treated by curative radiotherapy from February 2012 to June 2015. All patients ...

journal_title：Gynecologic oncology

authors： Tharavichitkul E,Chakrabandhu S,Klunklin P,Onchan W,Jia-Mahasap B,Wanwilairat S,Tippanya D,Jayasvasti R,Sripan P,Galalae RM,Chitapanarux I

更新日期：2018-03-01 00:00:00

abstract：:To identify women who find outpatient laser cervical surgery painful we designed a prospective observational study correlating surgical pain with multiple variables. The pain scoring systems were validated by comparing the subjective linear analogue score with an objective scoring method. The pain of surgery was compa...

journal_title：Gynecologic oncology

authors： Johnson N,Crompton AC

更新日期：1994-01-01 00:00:00

abstract：OBJECTIVE:The study was performed to evaluate the results of treatment of ovarian carcinoma after the introduction of centralised primary surgery in the County of North Jutland, Denmark. METHOD:Prospective study of consecutive cases of ovarian cancer undergoing primary surgical treatment at the Gynecologic Oncologic C...

journal_title：Gynecologic oncology

authors： Soegaard Andersen E,Knudsen A,Svarrer T,Lund B,Nielsen K,Grove A,Tetsche M

更新日期：2005-12-01 00:00:00