Inhibition of N-myc expression sensitizes human neuroblastoma IMR-32 cells expressing caspase-8 to TRAIL.

abstract：OBJECTIVES:Both interleukin-6 (IL-6) and transforming growth factor-beta (TGF-beta) are crucially involved in fibrotic events that characterize interstitial lung diseases (ILD). Therefore, the aim of this study was to investigate in primary cultures of normal and fibrotic human lung fibroblasts (HLF), exposed to either...

journal_title：Cell proliferation

authors： Gallelli L,Falcone D,Pelaia G,Renda T,Terracciano R,Malara N,Vatrella A,Sanduzzi A,D'Agostino B,Rossi F,Vancheri C,Maselli R,Marsico SA,Savino R

更新日期：2008-06-01 00:00:00

abstract：OBJECTIVES:To investigate the function and regulatory mechanism of Krüppel-like factor 3 (KLF3) in lung cancer. MATERIALS AND METHODS:KLF3 expression was analysed by qRT-PCR and Western blot assays. The proliferation, migration, invasion, cycle and apoptosis were measured by CCK-8 and EdU, wound-healing and Transwell,...

journal_title：Cell proliferation

authors： Wang R,Xu J,Xu J,Zhu W,Qiu T,Li J,Zhang M,Wang Q,Xu T,Guo R,Lu K,Yin Y,Gu Y,Zhu L,Huang P,Liu P,Liu L,De W,Shu Y

更新日期：2019-03-01 00:00:00

abstract：:Chronic kidney disease (CKD) is a severe health problem worldwide, and vascular calcification (VC) contributes substantially to the cardiovascular morbidity and high mortality of CKD. CKD is often accompanied by a variety of pathophysiological states, such as inflammation, oxidative stress, hyperglycaemia, hyperparath...

journal_title：Cell proliferation

authors： Zhang YX,Tang RN,Wang LT,Liu BC

更新日期：2021-01-27 00:00:00

abstract：OBJECTIVES:This study focuses on experimental analysis and corresponding mathematical simulation of in vitro HUVECs (human umbilical vein endothelial cells) proliferation in the presence of various types of drugs. MATERIALS AND METHODS:HUVECs, once seeded in Petri dishes, were expanded to confluence. Temporal profiles...

journal_title：Cell proliferation

authors： Mancuso L,Scanu M,Pisu M,Concas A,Cao G

更新日期：2010-12-01 00:00:00

abstract：OBJECTIVES:Advanced head and neck carcinomas (HNCs) are aggressive tumours, mainly due to hypoxia and a cancer stem cell (CSC) subpopulation. The aim of this study was to simulate tumour growth and behaviour during radiotherapy of three HNC groups (governed by different growth kinetics, hypoxia levels and CSC division ...

journal_title：Cell proliferation

authors： Marcu LG,Marcu D,Filip SM

更新日期：2016-06-01 00:00:00

abstract：:Epstein-Barr virus (EBV) infection in vitro causes transformation of B cells and generates B lymphoblastoid cell lines (LCLs). These LCLs have been widely used for the diagnostic of several genetic metabolic disorders. However, up to now, efficiency of LCL generation has been based on misleading subjective analysis. I...

journal_title：Cell proliferation

authors： Mello AS,Burin MG,Michellin K,Viapiana M,Giugliani R,Coelho JC,Bauer ME

更新日期：2006-02-01 00:00:00

abstract：:In vitro cultured Ehrlich ascites tumour (EAT) cells were used because of the ease of their manipulation under different levels of hypoxia. They were used to clarify further the complex mechanism of oxygen-dependent cell proliferation. On reducing the oxygen concentration from 20% to lower levels (1-7%) an increase in...

journal_title：Cell proliferation

authors： Löffler M

更新日期：1992-05-01 00:00:00

abstract：OBJECTIVES:Enterochromaffin (EC) cells have been associated with functional gastrointestinal disorders such as IBS. Recently, we found that glial cell-derived neurotrophic factor (GDNF)-rearranged during transfection (RET) localized in EC cells in human colonic epithelia. Here, we examine the role of GDNF-RET in the pa...

journal_title：Cell proliferation

authors： Lin L,Feng B,Zhou R,Liu Y,Li L,Wang K,Yu Y,Liu C,Long X,Gu X,Li B,Wang X,Yang X,Cong Y,Zuo X,Li Y

更新日期：2020-10-01 00:00:00

abstract：:A model of intestinal crypt organization is suggested based on the assumption that stem cells have a finite replicative life span. The model assumes the existence in a crypt of a quiescent ('deep') stem cell and a few more actively cycling ('proximate') stem cells. Monte Carlo computer simulation of published intestin...

journal_title：Cell proliferation

authors： Lobachevsky PN,Radford IR

更新日期：2006-10-01 00:00:00

abstract：OBJECTIVES:Oestrogen receptor (ER) is a common nucleus receptor that is essential for the regulation of cell growth, proliferation and differentiation. This study was to examine whether ERα can affect the proliferation and odonto/osteogenic differentiation of stem cells from apical papilla (SCAPs). MATERIALS AND METHO...

journal_title：Cell proliferation

authors： Wang Y,Lu Y,Li Z,Zhou Y,Gu Y,Pang X,Wu J,Gobin R,Yu J

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVES:BCL2 family proteins have been widely studied over the past decade due to their essential roles in apoptosis, oncogenesis and anti-cancer therapy. However, the similarities and differences in the spatial pattern of the BCL2 gene family within the context of chromatin have not been well characterized. We soug...

journal_title：Cell proliferation

authors： Wang J,Li S,Lin S,Fu S,Qiu L,Ding K,Liang K,Du H

更新日期：2020-06-01 00:00:00

abstract：OBJECTIVES:In order to provide a more comprehensive understanding of the effects of SARS-CoV-2 on oral health and possible saliva transmission, we performed RNA-seq profiles analysis from public databases and also a questionnaire survey on oral-related symptoms of COVID-19 patients. MATERIALS AND METHODS:To analyse AC...

journal_title：Cell proliferation

authors： Chen L,Zhao J,Peng J,Li X,Deng X,Geng Z,Shen Z,Guo F,Zhang Q,Jin Y,Wang L,Wang S

更新日期：2020-12-01 00:00:00

abstract：:In this paper we describe the application of a non-radioactive DNA double labelling and staining method to an analysis of cell proliferation kinetics by flow cytometry, aimed at the direct measurement of recruitment rates in cell cultures. The method is based on the application of two halogenated deoxyuridines: iodode...

journal_title：Cell proliferation

authors： Bakker PJ,de Vries RJ,Tukker CJ,Hoebe RA,Barendsen GW

更新日期：1993-01-01 00:00:00

abstract：:During brain development, a population of uniform embryonic cells migrates and differentiates into a large number of neural phenotypes - origin of the enormous complexity of the adult nervous system. Processes of cell proliferation, differentiation and programmed death of no longer required cells, do not occur only du...

journal_title：Cell proliferation

authors： Ulrich H,Bocsi J,Glaser T,Tárnok A

更新日期：2014-02-01 00:00:00

abstract：:On 31 May 2010, 14 072 567 bone marrow/apheresis donors registered in 44 countries and 426 501 cord blood units banked in 26 countries for public use were available to treat candidates to haemopoietic stem cell transplant lacking a family related compatible donor. Despite these impressive numbers, additional efforts a...

journal_title：Cell proliferation

authors： Rebulla P,Lecchi L

更新日期：2011-04-01 00:00:00

abstract：:Two groups of male rats were treated orally for 60 days with ebrotidine and cimetidine, used as reference standard, respectively. The dose used of both drugs was 500 mg/kg. A third group, used as control, received 10 ml/kg of an aqueous agar suspension. After receiving the last dose, the animals were killed by inhalat...

journal_title：Cell proliferation

authors： Romero A,Gómez F,Villamayor F,Sacristán A,Ortíz JA

更新日期：1995-07-01 00:00:00

abstract：:Programmed cell death (PCD)-apoptosis, autophagy and programmed necrosis-is any pathological form of cell death mediated by intracellular processes. Ototoxic drugs, ageing and noise exposure are some common pathogenic factors of sensorineural hearing loss (SNHL) that can induce the programmed death of auditory hair ce...

journal_title：Cell proliferation

authors： Wu J,Ye J,Kong W,Zhang S,Zheng Y

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVES:To evaluate the effects of rRNA synthesis inhibition on cell cycle progression and cell population growth according to the RB and p53 status. MATERIAL AND METHODS:RB- and p53-proficient U2OS cells and the RB- and p53-deficient SAOS-2 cells were used, rRNA transcription hindered by actinomycin D, and cell cy...

journal_title：Cell proliferation

authors： Montanaro L,Mazzini G,Barbieri S,Vici M,Nardi-Pantoli A,Govoni M,Donati G,Treré D,Derenzini M

更新日期：2007-08-01 00:00:00

abstract：:Proliferation and multidrug resistance status are key predictors of therapeutic outcome in acute myeloid leukaemia (AML). Anthracyclines such as daunorubicin (DNR) are typically used to treat AML and can induce drug resistance. The goal of the studies described here was to select a combination of fluorescent probes th...

journal_title：Cell proliferation

authors： Boutonnat J,Barbier M,Muirhead K,Mousseau M,Ronot X,Seigneurin D

更新日期：1999-08-01 00:00:00

abstract：OBJECTIVES:Curcumin, a natural compound, is a potent anti-cancer agent, which inhibits cell division and/or induces cell death. It is believed that normal cells are less sensitive to curcumin than malignant cells; however, the mechanism(s) responsible for curcumin's effect on normal cells are poorly understood. The aim...

journal_title：Cell proliferation

authors： Bielak-Zmijewska A,Sikora-Polaczek M,Nieznanski K,Mosieniak G,Kolano A,Maleszewski M,Styrna J,Sikora E

更新日期：2010-08-01 00:00:00

abstract：:Intra-erythrocytic Plasmodium species can be stained with the DNA binding dye, Hoechst 33342, and the distribution of DNA content determined for parasite populations by flow cytometric measurement of fluorescence. Analysis of this distribution will determine the parasitaemia (percentage of erythrocytes infected), and ...

journal_title：Cell proliferation

authors： Jacobberger JW,Horan PK,Hare JD

更新日期：1992-09-01 00:00:00

abstract：OBJECTIVES:To assess the expression, prognostic value, and functionality of T-lymphokine-activated killer (T-LAK) cell-originated protein kinase (TOPK) in chordoma pathogenesis. MATERIALS AND METHODS:TOPK expression in chordoma was assessed via immunohistochemical staining of a tissue microarray (TMA) and correlated w...

journal_title：Cell proliferation

authors： Thanindratarn P,Dean DC,Nelson SD,Hornicek FJ,Duan Z

更新日期：2020-10-01 00:00:00

abstract：OBJECTIVES:Cardiac atrial appendage stem cells (CASCs) have recently emerged as an attractive candidate for cardiac regeneration after myocardial infarction. As with other cardiac stem cells, CASCs have to be expanded ex vivo to obtain clinically relevant cell numbers. However, foetal calf serum (FCS), which is routine...

journal_title：Cell proliferation

authors： Windmolders S,Willems L,Daniëls A,Linsen L,Fanton Y,Hendrikx M,Koninckx R,Rummens JL,Hensen K

更新日期：2015-04-01 00:00:00

abstract：OBJECTIVES:To investigate behaviour and osteogenic cytokine expression of RAW264.7 macrophages grown on TiO2 nanotube layers. MATERIALS AND METHODS:The murine macrophage cell line RAW 264.7 was cultured on TiO2 nanotubes of varying diameter; macrophage morphology was examined using scanning electron microscopy. Cell a...

journal_title：Cell proliferation

authors： Sun SJ,Yu WQ,Zhang YL,Jiang XQ,Zhang FQ

更新日期：2013-12-01 00:00:00

abstract：:Neural stem cells (NSCs) are early precursors of neuronal and glial cells. NSCs are capable of generating identical progeny through virtually unlimited numbers of cell divisions (cell proliferation), producing daughter cells committed to differentiation. Nuclear factor kappa B (NF-kappaB) is an inducible, ubiquitous t...

journal_title：Cell proliferation

authors： Piotrowska MJ,Widera D,Kaltschmidt B,an der Heiden U,Kaltschmidt C

更新日期：2006-12-01 00:00:00

abstract：:In order to determine the role of micromilieu in tumour spheroid growth, a mathematical model was developed to predict EMT6/Ro spheroid growth and microenvironment based upon numerical solution of the diffusion/reaction equation for oxygen, glucose, lactate ion, carbon dioxide, bicarbonate ion, chlorine ion and hydrog...

journal_title：Cell proliferation

authors： Casciari JJ,Sotirchos SV,Sutherland RM

更新日期：1992-01-01 00:00:00

abstract：OBJECTIVES:This study is to explore the role of Notch signalling during the regeneration of rat tracheal epithelium after injury induced by 5-fluorouracil (5-FU). MATERIALS AND METHODS:We developed an ex vivo model of rat tracheal epithelial regeneration using 5-FU to induce injury. Expression levels of members of the...

journal_title：Cell proliferation

authors： Ma XB,Jia XS,Liu YL,Wang LL,Sun SL,Song N,Wang EH,Li F

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVES:Mouse embryonic stem cell (mESC) culture contains various heterogeneous populations, which serve as excellent models to study gene regulation in early embryo development. The heterogeneity is typically defined by transcriptional activities, for example, the expression of Nanog or Rex1 mRNA. Our objectives we...

journal_title：Cell proliferation

authors： Hao J,Yang X,Zhang C,Zhang XT,Shi M,Wang SH,Mi L,Zhao YT,Cao H,Wang Y

更新日期：2020-11-01 00:00:00

abstract：:The cell cycle is controlled by numerous mechanisms ensuring correct cell division. This review will focus on these mechanisms, i.e. regulation of cyclin-dependent kinases (CDK) by cyclins, CDK inhibitors and phosphorylating events. The quality checkpoints activated after DNA damage are also discussed. The complexity ...

journal_title：Cell proliferation

authors： Vermeulen K,Van Bockstaele DR,Berneman ZN

更新日期：2003-06-01 00:00:00

abstract：:The association between the phosphorylation status of the retinoblastoma protein, pRb and changes in cell cycle control caused by either protein kinase C (PKC) or protein kinase A (PKA) stimulation was evaluated in human myeloblastic leukaemia ML-1 cells. TPA-induced PKC activation resulted in dephosphorylation of pRb...

journal_title：Cell proliferation

authors： Reinach PS,Li T,Lu L

更新日期：2000-08-01 00:00:00