MicroRNA-599 regulates the development of Parkinson's disease through mediating LRRK2 expression.

abstract：OBJECTIVE:The aim of this project was to study the imaging characteristics of multi-detector CT (MDCT) in different types of malignant tumor in the common bile duct ampulla. PATIENTS AND METHODS:We examined 30 cases of pancreatic head cancer, 35 of terminal cholangiocarcinoma, 26 of ampullary carcinoma, and 40 of beni...

journal_title：European review for medical and pharmacological sciences

authors： Zhao DZ,Guo Y,Sun YP,Liu HM,Zhang Z,Ma QL,Wang YS,Chen CL

更新日期：2017-08-01 00:00:00

abstract：:Pneumatosis intestinalis is an uncommon condition characterized by the presence of gas in the bowel wall. We present the case of a 49-year-old man admitted to our Clinic for his 4 day long haematochezia. Colonoscopy revealed pneumatosis coli as a cause of the lower gastrointestinal bleeding. A wide range of diagnostic...

journal_title：European review for medical and pharmacological sciences

authors： Burgazli KM,Mericliler M,Greiner H,Göbel T,Erhardt A

更新日期：2013-09-01 00:00:00

abstract：OBJECTIVE:To elucidate whether microRNA-374b could participate in the development of lung cancer (LC) through downregulating PTEN (gene of phosphate and tensin homolog deleted on chromosome ten) expression via activating PI3K/Akt pathway. PATIENTS AND METHODS:Expression levels of microRNA-374b and PTEN in LC tissues a...

journal_title：European review for medical and pharmacological sciences

authors： Li J,Zhou Z,Xu FC,Li J,Zeng D,Cao XQ,Han Y

更新日期：2019-02-01 00:00:00

abstract：OBJECTIVE:To provide selectable microRNA for intervening diabetes mellitus diseases, NOD mice's expression of microRNA in pancreas tissues and blood under the exendin-4 intervention of was observed and the difference of microRNA target gene was screened. MATERIALS AND METHODS:Forty clean NOD mice were randomly divided...

journal_title：European review for medical and pharmacological sciences

authors： He JS,Lian CW,Fang YL,Wu JZ,Ye XL,Zhu SB

更新日期：2016-10-01 00:00:00

abstract：OBJECTIVE:To explore the effects of lamivudine on cell proliferation of liver cancer and expressions of HBsAg, HBeAg, and MMP-9 in hepatoma cells. MATERIALS AND METHODS:In the intervention group, HepG2.2.15 cells were cultured with lamivudine at 100, 200, and 300 μmol/L for 24 hours, 48 hours, and 72 hours. In the con...

journal_title：European review for medical and pharmacological sciences

authors： Zhang J,Yu H,Sun FY,Li J,Li DM,Sun CH

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:We aimed to assess the effects of irbesartan and nebivolol on the left atrium (LA) volume and deformation in the patients with mild-moderate hypertension. PATIENTS AND METHODS:The study comprised of 160 patients (mean age: 55.6±9.6 years), who had Stage 1 or 2 hypertension according to the European Society ...

journal_title：European review for medical and pharmacological sciences

authors： Degirmenci H,Duman H,Demirelli S,Bakirci EM,Hamur H,Inci S,Simsek Z,Askın L,Arısoy A,Lazoglu Z

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:To investigate the relations between the steatosis and liver functions, inflammations, and glucolipid metabolism in chronic hepatitis B patients. PATIENTS AND METHODS:A total of 144 chronic hepatitis B patients who were admitted to our hospital from January 2015 to April 2017 were selected and divided into t...

journal_title：European review for medical and pharmacological sciences

authors： Chen XL,Han YD,Wang H

更新日期：2018-09-01 00:00:00

abstract：OBJECTIVE:This study aims to investigate whether microRNA-373-3p could inhibit the progression of prostate cancer (PCa) by targeting and degrading AKT1. PATIENTS AND METHODS:Expression levels of microRNA-373-3p and AKT1 in PCa tissues and benign prostate hyperplasia (BPN) tissues were detected by quantitative Real-Tim...

journal_title：European review for medical and pharmacological sciences

authors： Qu HW,Jin Y,Cui ZL,Jin XB

更新日期：2018-10-01 00:00:00

abstract：OBJECTIVE:To explore the expression pattern and diagnostic value of microRNA-122 (miRNA-122) in childhood Kawasaki disease (KD). PATIENTS AND METHODS:A total of 150 children with KD were included in the KD group. During the same period, 150 children with respiratory infection complicated with fever and without myocard...

journal_title：European review for medical and pharmacological sciences

authors： Lv HF,Sun XQ,Zhou HX,Qin Z,Shi YY,Wang Q,Li F

更新日期：2020-11-01 00:00:00

abstract：INTRODUCTION:To investigate the relationship between the interleukin-10 (IL-10) gene polymorphism and the pathogenesis of diabetic retinopathy (DR). PATIENTS AND METHODS:According to the fundus examination report, 420 patients with diabetes were divided into the non-DR group (n=200) and the DR group (n=220). The singl...

journal_title：European review for medical and pharmacological sciences

authors： Shi YL,Shi MY,Yin LZ,Shang JM,Zhuang JY

更新日期：2019-06-01 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy of intrathecal dexmedetomidine at improving the quality of the operative field, and prolonging the duration of sensory block, motor block, and postoperative analgesia during spinal surgery PATIENTS AND METHODS:This prospective, double-blinded, randomized controlled study included 52 ...

journal_title：European review for medical and pharmacological sciences

authors： Salem RA,Darweesh EI,Wanis MA,Mohamed AA

更新日期：2015-12-01 00:00:00

abstract：OBJECTIVE:MiR-155-5p has various biological cellular functions in diverse pathology, including cardiovascular disease. Nevertheless, the role of miR-155-5p in atherosclerosis is still not well known. PATIENTS AND METHODS:The levels of miR-155-5p and AKT Serine/Threonine Kinase 1 (AKT1) in plasma samples from patients ...

journal_title：European review for medical and pharmacological sciences

authors： Chen L,Zheng SY,Yang CQ,Ma BM,Jiang D

更新日期：2019-03-01 00:00:00

abstract：OBJECTIVE:We aimed to assess the preoperative rectal cancer angiogenesis with Endorectal Power Doppler Ultrasonography by using the Power Doppler Vascularity Index (PDVI) calculated by imaging analysis software, and to compare it with the microvessel density (MVD) in surgical specimens PATIENTS AND METHODS: This study ...

journal_title：European review for medical and pharmacological sciences

authors： Tankova L,Nakov R,Stoilov G,Gegova A,Nakov V,Gerova V,Terziev I,Kovatchki D

更新日期：2019-02-01 00:00:00

abstract：OBJECTIVE:This paper aims at screening the common differential genes of coronary atherosclerotic heart disease (CAD) and ischemic cardiomyopathy (ICM), and to conduct pathway analysis and protein-protein interaction (PPI) network analysis for the differential genes. MATERIALS AND METHODS:The CAD and ICM datasets were ...

journal_title：European review for medical and pharmacological sciences

authors： Li GM,Zhang CL,Rui RP,Sun B,Guo W

更新日期：2018-06-01 00:00:00

abstract：OBJECTIVE:Recent researches have proved that long noncoding RNAs (lncRNAs) play essential roles in tumorigenesis. The aim of this study was to investigate the exact role of lncRNA DLX6-AS1 in the development of colorectal cancer (CRC), and to explore the possible mechanism. PATIENTS AND METHODS:DLX6-AS1 expression in ...

journal_title：European review for medical and pharmacological sciences

authors： Zhou FR,Pan ZP,Shen F,Huang LQ,Cui JH,Cai K,Guo XL

更新日期：2019-05-01 00:00:00

abstract：OBJECTIVE:To investigate the relationship between the meniscal defect area and OA progression and explore the effect and mechanism of SMSCs cell therapy in knee osteoarthritis (OA) rat model. MATERIALS AND METHODS:For animal experiments, knee osteoarthritis (OA) model was constructed in Sprague Dawley (SD) rats by rem...

journal_title：European review for medical and pharmacological sciences

authors： Qiong J,Xia Z,Jing L,Haibin W

更新日期：2020-02-01 00:00:00

abstract：OBJECTIVE:Atherosclerosis leads to increased arterial resistance through thickening and stiffening of the arterial wall, a phenomenon largely known as arterial stiffness. M-mode propagation velocity of the descending thoracic aorta, named aortic velocity propagation (AVP) is a novel method for the measurement of the ao...

journal_title：European review for medical and pharmacological sciences

authors： Yaman M,Arslan U,Beton O,Pamukcu HE,Dogdu O

更新日期：2016-03-01 00:00:00

abstract：OBJECTIVE:To investigate the effects of recombinant activated coagulation factor VII (rFVIIa) on apoptosis and the expressions of B-cell lymphoma 2 (Bcl-2) and Bcl-2-associated X protein (Bax) in rats with intracerebral hemorrhage (ICH). MATERIALS AND METHODS:A total of 90 8-week-old male Sprague-Dawley (SD) rats with...

journal_title：European review for medical and pharmacological sciences

authors： Ma YM,Zheng JX,Xu X,Shan YS,Gao ZW,Chen WG

更新日期：2018-08-01 00:00:00

abstract：OBJECTIVE:To explore the expression and function of insulin-like growth factor II (IGFII) mRNA binding protein (IMP3) in the Triple Negative Breast Cancer (TNBC). MATERIALS AND METHODS:According to previously reported gene expression array, we found that IMP3 had significantly higher expression in the CD44+CD24-ESA+ c...

journal_title：European review for medical and pharmacological sciences

authors： Huang QD,Zheng SR,Cai YJ,Chen DL,Shen YY,Lin CQ,Hu XQ,Wang XH,Shi H,Guo GL

更新日期：2018-05-01 00:00:00

abstract：OBJECTIVE:We studied the influence of Dexmedetomidine on cognitive function in children during the recovery period of general anesthesia. PATIENTS AND METHODS:Ninety-three children who underwent general anesthesia were selected and randomly divided into (1) the control group, (2) the dexmedetomidine group, and (3) the...

journal_title：European review for medical and pharmacological sciences

authors： Jia ZM,Hao HN,Huang ML,Ma DF,Jia XL,Ma B

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to investigate the expression level of microRNA-21-5p and its target gene PLAG1 in the serum of patients with spinal cord injury (SCI), as well as the role and mechanism of microRNA-21-5p in lipopolysaccharide-induced primary microglial inflammation. PATIENTS AND METHODS:The levels ...

journal_title：European review for medical and pharmacological sciences

authors： Han K,Wang FR,Yu MQ

更新日期：2020-06-01 00:00:00

abstract：OBJECTIVE:In this study, we investigated whether the administration of calcium dobesilate (CD) affects oxidative stress markers and histopathological outcomes in a rat model of intestinal ischemia-reperfusion (IR) injury. MATERIALS AND METHODS:This study was conducted with 30 male Wistar rats. The rats were randomly a...

journal_title：European review for medical and pharmacological sciences

authors： Seker A,Bardakci O,Eryilmaz S,Kocarslan S,Incebiyik A,Yucel Y,Taskin A,Soyalp M,Gokalp O,Uzunkoy A

更新日期：2016-05-01 00:00:00

abstract：OBJECTIVE:This study aimed to detect the expression of microRNA-378 in OSCC, and further studies its effects on clinicopathology and prognosis of OSCC patients. PATIENTS AND METHODS:Real-Time quantitative Polymerase Chain Reaction (RT-qPCR) was used to detect the expression levels of microRNA-378 in 96 pairs of OSCC t...

journal_title：European review for medical and pharmacological sciences

authors： Ding N,Luo M,Liao XL,Bao QY,Li RY,Wu B

更新日期：2019-07-01 00:00:00

abstract：:Many factors have been identified to influence the risk of mother to child transmission (MTCT) of HIV. Chief amongst these is high maternal VL and advanced disease. High maternal viral load (mVL), measured at delivery, has been described as the strongest risk factor for both in utero (IU) and intrapartum (IP) transmis...

journal_title：European review for medical and pharmacological sciences

authors： Liu JF,Liu G,Li ZG

更新日期：2017-10-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to investigate the expression level and potential molecular mechanism of microRNA-1324 in gastric cancer (GCa) to provide a new perspective for the diagnosis and treatment of GCa. PATIENTS AND METHODS:The expression levels of microRNA-1324 and MECP2 in GCa tissues and cell lines wer...

journal_title：European review for medical and pharmacological sciences

authors： Zhang XY,Xu YY,Chen WY

更新日期：2020-05-01 00:00:00

abstract：CASE PRESENTATION:Diffuse large B-cell lymphoma (DLBCL) is the most common lymphoid malignancy and the most common type of non-Hodgkin's lymphomas, the stomach is the most common extranodal site. Gastric DLBCL is often characterized by epigastric pain and vomiting. We report a case of a 78-year-old female patient with ...

journal_title：European review for medical and pharmacological sciences

authors： Zhao KX,Dai GZ,Zhu JF

更新日期：2016-05-01 00:00:00

abstract：:Internal abdominal hernias are a rare cause of intestinal obstruction (0.2-0.9%). Transmesenteric hernia is a rare type of internal hernia and usually in adult people is acquired. We report the case of a 44 year-old caucasian female with a small bowel occlusion after right nephrectomy for clear cell renal carcinoma ca...

journal_title：European review for medical and pharmacological sciences

authors： Di Rocco G,Casella G,Giannotti D,Bernieri MG,Marchetti M,Iavarone C,Trapè S,Patrizi G,Redler A

更新日期：2013-03-01 00:00:00

abstract：OBJECTIVE:The application of quantitative EEG (δ+θ/α+β value) and GCS value to evaluate the role of music therapy for traumatic brain injury coma patients. PATIENTS AND METHODS:Forty patients of traumatic brain injury coma were selected to meet the inclusion criteria. Twenty cases were selected for the rehabilitation,...

journal_title：European review for medical and pharmacological sciences

authors： Sun J,Chen W

更新日期：2015-04-01 00:00:00

abstract：AIM:To investigate the impacts of infectious complications on mortality and morbidity; and to identify the other potential factors effective in mortality in peritoneal dialysis (PD) patients. PATIENTS AND METHODS:We included patients who initiated therapy between 2001-2011. Patients were divided into two groups regard...

journal_title：European review for medical and pharmacological sciences

authors： Sinangil A,Koc Y,Unsal A,Basturk T,Sakaci T,Ahbap E,Budak SK,Doner B,Sevinc M

更新日期：2013-04-01 00:00:00

abstract：:Atherosclerosis, the hardening of arteries under oxidative stress is related to oxidative changes of low density lipoproteins (LDL). The antioxidants prevent the formation of oxidized LDL during atherogenesis. Perhaps more than one mechanism is involved in the atherosclerosis disease where LDL is oxidized in all the c...

journal_title：European review for medical and pharmacological sciences

authors： Zhang PY,Xu X,Li XC

更新日期：2014-10-01 00:00:00