Factors responsible for mother to child transmission (MTCT) of HIV-1 - a review.

Abstract:

:Many factors have been identified to influence the risk of mother to child transmission (MTCT) of HIV. Chief amongst these is high maternal VL and advanced disease. High maternal viral load (mVL), measured at delivery, has been described as the strongest risk factor for both in utero (IU) and intrapartum (IP) transmission. Similarly, CD4+ T cell count and clinical stage of infection are also the confirmed significant predictors of transmission. Correspondingly, higher mVL in the genital tract has also been independently associated with a higher risk of MTCT of HIV-1. So, the present review article would put light on various aspects of factors responsible for MTCT of HIV in pediatric patients.

authors

Liu JF,Liu G,Li ZG

subject

Has Abstract

pub_date

2017-10-01 00:00:00

pages

74-78

issue

4 Suppl

eissn

1128-3602

issn

2284-0729

journal_volume

21

pub_type

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