Abstract:
OBJECTIVE:Vesicoureteral reflux (VUR) affects up to 1% of Caucasian children. Primary VUR is characterized by failure of the ureterovesicular junction to prevent urine from traveling in a retrograde fashion from the bladder to the ureters and the kidneys. Several reports in the literature describe the prevalence of this condition in pediatric patients; overall, VUR affects more males during infancy and with higher grades. However, a thorough consideration of these articles reveals important contradictions regarding the prevalence by gender and age. We analyzed those contradictions and suggested a possible explanation based on our single center experience with this patient group. In particular, for the age interval 0-2 years: we have found that (1) VUR mostly affects boys; (2) the male/female ratio steadily declines over time; (3) the unequal prevalence between males and females essentially disappears when children reach the age of two years. CONCLUSIONS:The natural history of VUR in infant boys differs from that of infant girls, and therefore requires a gender-specific approach. Available data support the need to redefine the categorization and clinical guidelines for this disease.
journal_name
Eur Rev Med Pharmacol Scijournal_title
European review for medical and pharmacological sciencesauthors
Capozza N,Gulia C,Heidari Bateni Z,Zangari A,Gigli S,Briganti V,Tursini S,Koh CJ,Gaffi M,Baldassarra S,Signore F,Porrello A,Piergentili Rdoi
10.26355/eurrev_201712_13916subject
Has Abstractpub_date
2017-12-01 00:00:00pages
5321-5329issue
23eissn
1128-3602issn
2284-0729journal_volume
21pub_type
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journal_title:European review for medical and pharmacological sciences
pub_type: 杂志文章
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journal_title:European review for medical and pharmacological sciences
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更新日期:2019-05-01 00:00:00
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更新日期:2017-07-01 00:00:00
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