In Silico Roots: Room for Growth.

Abstract:

:Computational models are invaluable tools for understanding the hormonal and genetic control of root development. Thus far, models have focused on the crucial roles that auxin transport and metabolism play in determining the auxin signaling gradient that controls the root meristem. Other hormones such as cytokinins, gibberellins, and ethylene have predominantly been considered as modulators of auxin dynamics, but their underlying patterning mechanisms are currently unresolved. In addition, the effects of cell- and tissue-level growth dynamics, which induce dilution and displacement of signaling molecules, have remained unexplored. Elucidating these additional mechanisms will be essential to unravel how root growth is patterned in a robust and self-organized manner. Models incorporating growth will thus be crucial in unraveling the underlying logic of root developmental decision making.

journal_name

Trends Plant Sci

journal_title

Trends in plant science

authors

Rutten JP,Ten Tusscher K

doi

10.1016/j.tplants.2018.11.005

subject

Has Abstract

pub_date

2019-03-01 00:00:00

pages

250-262

issue

3

eissn

1360-1385

issn

1878-4372

pii

S1360-1385(18)30267-X

journal_volume

24

pub_type

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