Heart rate variability for treatment response between patients with major depressive disorder versus panic disorder: A 12-week follow-up study.

Abstract:

BACKGROUND:Heart Rate Variability (HRV) parameters have been used to evaluate the autonomic nervous system. We hypothesized that patients with major depressive disorder (MDD) and panic disorder (PD) showed different HRV profiles compared to healthy controls. We also hypothesized that we could predict the responder groups in the MDD and PD patients, using differences in HRV indices between the stress and rest phases. METHODS:28 MDD patients and 29 PD patients were followed for 12 weeks, and we also followed 39 healthy control subjects. We measured HRV parameters at the rest, stress, and recovery phases. RESULTS:Patients with MDD and PD demonstrated lower pNN50 than controls during the stress (F = 7.49, p = 0.001), and recovery phases (F = 9.43, p = 0.0001). Patients with MDD and PD also showed higher LF/HF ratio than controls during the stress phase (F = 6.15, p = 0.002). Responders in the PD group presented a lower level of LF/HF ratio during the stress phase compared to non-responders (F = 10.14, p = 0.002), while responders in the MDD group showed a lower level of heart rate during all three phases, compared to non-responders. Additionally, we could predict treatment response in patients with MDD using ΔLF/HF ratio (OR: 1.33, 95% CI = 1.07-1.65, p = 0.011) and ΔpNN50 (OR: 1.49, 95% CI 1.09-1.77, p = 0.014). CONCLUSION:The changes of HRV parameters of pNN50 and LF/HF ratio between the stress and recovery phase may be clinical markers of predictors of treatment responsiveness in MDD and PD patients.

journal_name

J Affect Disord

authors

Choi KW,Jang EH,Kim AY,Fava M,Mischoulon D,Papakostas GI,Kim DJ,Kim K,Yu HY,Jeon HJ

doi

10.1016/j.jad.2018.12.048

subject

Has Abstract

pub_date

2019-03-01 00:00:00

pages

157-165

eissn

0165-0327

issn

1573-2517

pii

S0165-0327(18)31014-0

journal_volume

246

pub_type

临床试验,杂志文章
  • Prevalence of mixed mania using 3 definitions.

    abstract:OBJECTIVES:Mixed episodes are a combination of depressive and manic symptoms in bipolar disorder (BD). We want to identify the proportion of patients who have depressive symptoms during an acute episode and also the validity of current methods for its diagnosis. MATERIAL AND METHOD:Cross-sectional multicentre study of...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2009.12.019

    authors: Vieta E,Morralla C

    更新日期:2010-09-01 00:00:00

  • Antidepressive effect of left dorsolateral prefrontal cortex neurofeedback in patients with major depressive disorder: A preliminary report.

    abstract::Background Real-time functional magnetic resonance imaging neurofeedback (rtfMRI-nf) have recently attracted attention as a novel, individualized treatment method for major depressive disorder (MDD). In this study, the antidepressant effect of neurofeedback training for left dorsolateral prefrontal cortex (DLPFC) acti...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2020.03.080

    authors: Takamura M,Okamoto Y,Shibasaki C,Yoshino A,Okada G,Ichikawa N,Yamawaki S

    更新日期:2020-06-15 00:00:00

  • Antidepressant drug use in Lombardy, Italy: a population-based study.

    abstract:BACKGROUND:The patterns of antidepressant drug prescribing have rarely been studied in large and geographically defined catchment areas. In the present study, we examined the prevalence and distribution of antidepressant prescribing in Lombardy, a northern Italy region of nine million inhabitants. METHODS:This study u...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2004.07.005

    authors: Percudani M,Barbui C,Fortino I,Petrovich L

    更新日期:2004-12-01 00:00:00

  • Response style, interpersonal difficulties and social functioning in major depressive disorder.

    abstract:BACKGROUND:It is postulated that depressed patients who engaged in self-focused rumination on their depressive symptoms may experience more hopelessness, more interpersonal distress and poorer social functioning while patients who distract themselves may experience less severe hopelessness and better social functioning...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/s0165-0327(02)00058-7

    authors: Lam D,Schuck N,Smith N,Farmer A,Checkley S

    更新日期:2003-08-01 00:00:00

  • Effect of transcutaneous auricular vagus nerve stimulation on major depressive disorder: A nonrandomized controlled pilot study.

    abstract:BACKGROUND:Depression presents a significant burden to both patients and society. One treatment that has emerged is vagus nerve stimulation (VNS), an FDA-approved physical treatment for depressive disorders. However, the application of this intervention has been limited by the involvement of surgery and potential side ...

    journal_title:Journal of affective disorders

    pub_type: 临床试验,杂志文章

    doi:10.1016/j.jad.2016.02.031

    authors: Rong P,Liu J,Wang L,Liu R,Fang J,Zhao J,Zhao Y,Wang H,Vangel M,Sun S,Ben H,Park J,Li S,Meng H,Zhu B,Kong J

    更新日期:2016-05-01 00:00:00

  • A report on mood and cognitive outcomes with right unilateral ultrabrief pulsewidth (0.3 ms) ECT and retrospective comparison with standard pulsewidth right unilateral ECT.

    abstract:BACKGROUND:Electroconvulsive therapy (ECT) is a highly effective treatment for depression but its use is limited by the risk of cognitive side effects. This study explored the potential of a novel approach, ultrabrief pulsewidth (0.3 ms) right unilateral (RUL-UB) ECT, to minimise cognitive effects while preserving effi...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2007.06.012

    authors: Loo C,Sheehan P,Pigot M,Lyndon W

    更新日期:2007-11-01 00:00:00

  • Does guideline-concordant care predict naturalistic outcomes in youth with early stage bipolar I disorder?

    abstract:BACKGROUND:The impact of guideline concordance on naturalistic maintenance treatment outcomes in BD is not known. We sought to evaluate the effect of guideline-concordant care on symptomatic, course and functional outcomes in youth with early-stage BD-I. METHODS:In this file audit study, we examined the prospective co...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2020.09.037

    authors: Sunder P,Chia MF,Filia K,Macneil C,Hasty M,Davey C,McGorry P,Berk M,Cotton S,Ratheesh A

    更新日期:2021-01-01 00:00:00

  • Examining reward-seeking, negative self-beliefs and over-general autobiographical memory as mechanisms of change in classroom prevention programs for adolescent depression.

    abstract:BACKGROUND:Effective methods to prevent adolescent depressive symptoms could reduce suffering and burden across the lifespan. However, psychological interventions delivered to adolescents show efficacy only in symptomatic or high-risk youth. Targeting causal risk factors and assessing mechanistic change can help devise...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2015.07.019

    authors: Rice F,Rawal A,Riglin L,Lewis G,Lewis G,Dunsmuir S

    更新日期:2015-11-01 00:00:00

  • The neurochemistry of mania. The effect of lithium on catecholamines, indoleamines and calcium mobilization.

    abstract::In an attempt to elucidate the chemical pathology of mania one has to consider the pharmacology of the two most effective treatments for this illness: lithium and the neuroleptics. Some of the possible mechanisms of action of these drugs on catecholamine and indoleamine mechanisms are discussed. The majority of this a...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/0165-0327(85)90019-9

    authors: Wood K

    更新日期:1985-05-01 00:00:00

  • Momentary changes in the cardiovascular autonomic system during mental loading in patients with panic disorder: a new physiological index "rho(max)".

    abstract:BACKGROUND:Although panic disorder (PD) is suggestive of autonomic nervous system dysfunction, especially in the cardiovascular autonomic system (CAS), the results in many previous studies are still controversial. Using a new physiological index which could well reflect emotional reaction to visual stimuli (Yoshizawa, ...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2004.03.008

    authors: Shioiri T,Kojima M,Hosoki T,Kitamura H,Tanaka A,Bando T,Someya T

    更新日期:2004-11-01 00:00:00

  • Light room therapy effective in mild forms of seasonal affective disorder--a randomised controlled study.

    abstract:BACKGROUND:The most common way to provide bright light therapy to Swedish patients with Seasonal Affective Disorder (SAD), is treatment in a light therapy room. Since few studies have evaluated treatment provided in this setting and few have evaluated the effect of bright light in sub-clinical SAD (S-SAD), such a study...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.jad.2007.10.009

    authors: Rastad C,Ulfberg J,Lindberg P

    更新日期:2008-06-01 00:00:00

  • The effects of ethnic, social and cultural factors on axis I comorbidity of bipolar disorder: results from the clinical setting in Korea.

    abstract:OBJECTIVE:Ethnic, social and cultural factors contribute to axis I comorbid conditions in bipolar disorder (BPD). Korea has strict laws against illicit drugs and a relatively permissive prevailing attitude toward alcohol. The present study aimed to explore the lifetime axis I comorbidity rate in patients with BPD in Ko...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2014.05.027

    authors: Baek JH,Cha B,Moon E,Ha TH,Chang JS,Kim JH,Choi JE,Kang BJ,Hong KS,Ha K

    更新日期:2014-09-01 00:00:00

  • Anti-brain antibodies in adult patients with obsessive-compulsive disorder.

    abstract:BACKGROUND:An autoimmune hypothesis has been suggested for a subtype of Obsessive-Compulsive Disorder (OCD) with childhood onset: obsessions, compulsions and/or tics would result from anti-streptococcal antibodies that cross-react with basal ganglia tissue based on molecular mimicry. Consistent with this hypothesis ant...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2008.11.019

    authors: Maina G,Albert U,Bogetto F,Borghese C,Berro AC,Mutani R,Rossi F,Vigliani MC

    更新日期:2009-08-01 00:00:00

  • Attentional control, rumination and recurrence of depression.

    abstract:BACKGROUND:Depressive recurrence is highly prevalent and adds significantly to the burden of depressive disorder. Whilst some clinical predictors of recurrence have been clearly demonstrated (e.g. residual symptoms, previous episodes), the cognitive and psychological processes that may contribute to recurrence risk are...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2019.05.072

    authors: Figueroa CA,DeJong H,Mocking RJT,Fox E,Rive MM,Schene AH,Stein A,Ruhé HG

    更新日期:2019-09-01 00:00:00

  • Type D personality and persistence of depressive symptoms in a German cohort of cardiac patients.

    abstract:BACKGROUND:Depression is associated with a negative prognosis in coronary heart disease and heart failure patients. Type D personality has been shown to predict the persistence of depressive symptoms over 12 months. Data on longer follow-up periods and on the effectiveness of Type D as a screening tool compared to esta...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2011.11.044

    authors: Romppel M,Herrmann-Lingen C,Vesper JM,Grande G

    更新日期:2012-02-01 00:00:00

  • Timing of depression recurrence in the first year after birth.

    abstract:BACKGROUND:Women who have suffered from one episode of postpartum-onset major depression (PPMD) experience increased risk for recurrence in the year following another birth. METHODS:Non-depressed women (N=51) who had at least one past episode of PPMD were recruited during pregnancy. After birth, subjects were assessed...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/S0165-0327(02)00305-1

    authors: Wisner KL,Perel JM,Peindl KS,Hanusa BH

    更新日期:2004-03-01 00:00:00

  • Dependency, matching adversities, length of survival and relapse in major depression.

    abstract::This paper reports the 1-year follow-up of a sample of depressed patients. Social cognitive variables obtained during the index episode, including ideal emotional support, roles and goals investment in various domains and dysfunctional attitudes were used to predict subjects' likelihood for subsequent relapse. More su...

    journal_title:Journal of affective disorders

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/0165-0327(95)00075-5

    authors: Lam DH,Green B,Power MJ,Checkley S

    更新日期:1996-04-12 00:00:00

  • Validation of the brief TEMPS-M temperament questionnaire in a clinical Italian sample of bipolar and cyclothymic patients.

    abstract:BACKGROUND:To assess psychometric proprieties of the short version of TEMPS-M in an Italian clinical sample of patients with bipolar disorder type I (BDI), type II (BDI) or cyclothymic disorder (CYC). METHODS:All participants were recruited in two Italian university sites. They were asked to complete the Italian versi...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2019.09.034

    authors: Fico G,Luciano M,Sampogna G,Zinno F,Steardo L Jr,Perugi G,Pompili M,Tortorella A,Volpe U,Fiorillo A,Maj M

    更新日期:2020-01-01 00:00:00

  • The Koukopoulos Mixed Depression Rating Scale (KMDRS): An International Mood Network (IMN) validation study of a new mixed mood rating scale.

    abstract:BACKGROUND:It has been proposed that the broad major depressive disorder (MDD) construct is heterogenous. Koukopoulos has provided diagnostic criteria for an important subtype within that construct, "mixed depression" (MxD), which encompasses clinical pictures characterized by marked psychomotor or inner excitation and...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2018.01.025

    authors: Sani G,Vöhringer PA,Barroilhet SA,Koukopoulos AE,Ghaemi SN

    更新日期:2018-05-01 00:00:00

  • CRMP2 mediates GSK3β actions in the striatum on regulating neuronal structure and mania-like behavior.

    abstract:BACKGROUND:Genetic and physiological studies have implicated the striatum in bipolar disorder (BD). Although Glycogen synthase kinase 3 beta (GSK3β) has been suggested to play a role in the pathophysiology of BD since it is inhibited by lithium, it remains unknown how GSK3β activity might be involved. Therefore we exam...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2018.10.371

    authors: Kim W,Won SY,Yoon BJ

    更新日期:2019-02-15 00:00:00

  • Reduced olfactory sensitivity in subjects with depressive symptoms.

    abstract:BACKGROUND:Clinical studies suggest that olfactory sensitivity is reduced in major depression. Nevertheless, only little is known about the relationship between depressive symptoms and olfactory functions in healthy subjects. METHODS:The present study investigated the association between depressive symptoms and olfact...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2006.12.012

    authors: Pollatos O,Albrecht J,Kopietz R,Linn J,Schoepf V,Kleemann AM,Schreder T,Schandry R,Wiesmann M

    更新日期:2007-09-01 00:00:00

  • Peripheral proinflammatory cytokines in Chinese patients with generalised anxiety disorder.

    abstract:BACKGROUND:Inflammatory responses and inflammatory cytokines have been implicated in the pathogenesis of affective disorders, particularly major depression. Given the limited evidence relating to the potential role of proinflammatory cytokines in generalised anxiety disorder (GAD), we aimed to examine peripheral proinf...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2017.08.082

    authors: Tang Z,Ye G,Chen X,Pan M,Fu J,Fu T,Liu Q,Gao Z,Baldwin DS,Hou R

    更新日期:2018-01-01 00:00:00

  • Effects of transcranial direct current stimulation for treating depression: A modeling study.

    abstract:BACKGROUND:Transcranial direct current stimulation (tDCS) above the left dorsolateral prefrontal cortex (lDLPFC) has been widely used to improve symptoms of major depressive disorder (MDD). However, the effects of different stimulation protocols in the entire frontal lobe have not been investigated in a large sample in...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2018.02.077

    authors: Csifcsák G,Boayue NM,Puonti O,Thielscher A,Mittner M

    更新日期:2018-07-01 00:00:00

  • Trajectory of cost overtime after psychotherapy for depression in older Veterans via telemedicine.

    abstract:BACKGROUND:Little evidence exists regarding the costs of telemedicine, especially considering changes over time. This analysis aimed to analyze trajectory of healthcare cost before, during, and after a behavioral activation intervention delivered via telepsychology and same-room delivery to elderly Veterans with depres...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.jad.2016.09.044

    authors: Egede LE,Gebregziabher M,Walker RJ,Payne EH,Acierno R,Frueh BC

    更新日期:2017-01-01 00:00:00

  • Assessing the role of the amygdala in fear of pain: Neural activation under threat of shock.

    abstract:INTRODUCTION:The DSM-5 explicitly states that the neural system model of specific phobia is centered on the amygdala. However, this hypothesis is predominantly supported by human studies on animal phobia, whereas visual cuing of other specific phobias, such as dental fear, do not consistently show amygdala activation. ...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2020.07.110

    authors: Sambuco N,Costa VD,Lang PJ,Bradley MM

    更新日期:2020-11-01 00:00:00

  • Angiotensin-(1-7) central administration induces anxiolytic-like effects in elevated plus maze and decreased oxidative stress in the amygdala.

    abstract::There is increasing evidence that besides the well-known angiotensin (Ang) II, other renin-angiotensin system (RAS) peptides, including Ang-(1-7), could have important effects at the central level. However, very few things are known about the central actions of Ang-(1-7), while the effects of its administration alone ...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2012.07.024

    authors: Bild W,Ciobica A

    更新日期:2013-02-20 00:00:00

  • The effectiveness of internet-delivered cognitive behavioural therapy for health anxiety in routine care.

    abstract:INTRODUCTION:Randomised controlled trials have shown that internet-delivered cognitive behavioural treatment (iCBT) is an effective treatment for health anxiety, but the effectiveness of these programs in routine care has not been investigated. This study examined the effectiveness of iCBT for health anxiety symptoms i...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2019.11.087

    authors: Newby JM,Haskelberg H,Hobbs MJ,Mahoney AEJ,Mason E,Andrews G

    更新日期:2020-03-01 00:00:00

  • Cerebral ventricular size in panic disorder.

    abstract::Computed axial brain tomography was studied in 25 patients with panic disorder. Patients had normal ventricular-brain ratio (VBR) compared to published norms. There was a significant association between VBR and duration of benzodiazepine use. ...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/0165-0327(87)90011-5

    authors: Uhde TW,Kellner CH

    更新日期:1987-03-01 00:00:00

  • Suicide in Serbia.

    abstract:BACKGROUND:Suicide remains a significant public health problem worldwide. The aim of this study was to assess the mortality trend of suicide in Serbia for the years 1991-2014. METHODS:Data on persons who died of suicide and self-inflicted injury (site codes E950-E959 revision 9 and X60-X84 revision 10 of the Internati...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2015.12.063

    authors: Ilic M,Ilic I

    更新日期:2016-03-15 00:00:00

  • Life events and depression. Part 1. Effect of sex, age and civil status.

    abstract::This is the first of three articles dealing with some basic aspects of the relationship between life events and depression, and is also one part of a larger study in which the possible impact of stressful events has been studied from a multifactorial point of view. Two-hundred and four patients suffering from a depres...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/0165-0327(84)90060-0

    authors: Perris H

    更新日期:1984-08-01 00:00:00