Abstract：
:The present study describes a wheel turn/tail flick paradigm that was designed to simultaneously assess nociceptive thresholds of responses organized at spinal and supraspinal levels of the CNS in the rat. The paradigm involves training rats to perform an operant wheel turn response in order to escape current applied to the tail. Thresholds for the supraspinally organized escape response and the spinally organized tail flick reflex were determined via the psychophysical method of constant stimuli. Response latencies for wheel turn escape and tail flick were recorded to determine whether changes in nociceptive thresholds were confounded with changes in motor performance. The systemic administration of 3 mg/kg morphine sulfate elevated thresholds for both responses, but escape thresholds were elevated to a greater degree than tail flick thresholds. Because response latencies at threshold were not affected by morphine treatment, it appears that performance deficits did not contribute to the increase in thresholds. Advantage of these psychophysical procedures in assessing nociceptive responding in animals are discussed.
journal_name
Physiol Behavjournal_title
Physiology & behaviorauthors
Borszcz GS,Lichtman AH,Hughes HCdoi
10.1016/0031-9384(90)90028-3subject
Has Abstractpub_date
1990-05-01 00:00:00pages
1017-22issue
5eissn
0031-9384issn
1873-507Xpii
0031-9384(90)90028-3journal_volume
47pub_type
杂志文章abstract：:In unanesthetized cats the emetic action of an injection of nicotine into the cerebral ventricle through chronically implanted cannulae was investigated. Nicotine injected in doses of 0.02-1.0 mg produced dose-dependent vomiting, which was abolished after ablation of the area postrema. However, copper sulfate given in...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(87)90250-2
更新日期：1987-01-01 00:00:00
abstract：:Exercise-related affective responses, particularly in-task, have been implicated as influencing behavioral maintenance. An extensive body of literature, primarily using aerobic modes in laboratory settings, has identified a relatively consistent inverse relationship between intensity and affect. This relationship is p...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2020.113261
更新日期：2021-03-01 00:00:00
abstract：:The relationship between breakfast composition and cognitive performance was examined in elementary school children. Two experiments compared the effects of two common U.S. breakfast foods and no breakfast on children's cognition. Using a within-participant design, once a week for 3 weeks, children consumed one of two...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2005.06.023
更新日期：2005-08-07 00:00:00
abstract：UNLABELLED:Acute stress responses of women are typically more reactive than that of men. Women, compared to men, may be more vulnerable to posttraumatic stress disorder (PTSD). Whether there are differences between women and men with PTSD in levels of the stress hormone, cortisol, was investigated in a pilot study. ME...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2009.06.002
更新日期：2010-02-09 00:00:00
abstract：:Due to previous work where we have demonstrated attenuated febrile responses post-lipopolysaccharide (LPS) in calorie restricted (CR) rodents we aimed to explore metabolic rate and behavioral thermoregulation in these CR animals post-LPS. Male Sprague-Dawley rats fed ad libitum (AL) or restricted to 50% (CR50%) of the...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2012.06.009
更新日期：2012-12-05 00:00:00
abstract：:The present study examined responsiveness of newborn rats to a surrogate nipple providing fluids with basic tastes (sweet, sour, bitter and salty) and assessed the effects of this first gustatory experience on subsequent responding to the nipple itself (empty nipple) or the nipple providing water. Responsiveness (atta...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(01)00672-2
更新日期：2002-06-01 00:00:00
abstract：:Reaction times and perceived intensities for NaCl solutions were measured in sixteen human adults. Stimulus delivery was by means of a circular piece of solution-soaked filter paper held with forceps. The reaction time (T) decreased and the perceived intensity (S) increased with increasing the concentration (C) of NaC...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(82)90369-9
更新日期：1982-07-01 00:00:00
abstract：:Chronic exercise is considered as one of the most effective means of countering symptoms of the metabolic syndrome (MS) such as obesity and hyperglycemia. Rodent models of forced or voluntary exercise are often used to study the mechanisms of MS and type 2 diabetes. However, there is little known on the impact of gene...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2015.10.025
更新日期：2016-01-01 00:00:00
abstract：:Exposure of rats to an open-field results in a rapid rise in body temperature. Fifty-four percent of this rise in body temperature was blocked by intracerebroventricular administration of the antipyretic drug sodium salicylate. Intraperitoneal administration of indomethacin, a potent blocker of prostaglandin productio...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(87)90263-0
更新日期：1987-01-01 00:00:00
abstract：:Oxytocin and prolactin are potential candidates for the regulation of behavioral and physiological stress responses in the brain. To investigate the neurobiological basis of individual differences in stress responses in cattle, we examined the association of behavioral and hypothalamo-pituitary-adrenal axis reactivity...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2009.11.016
更新日期：2010-03-03 00:00:00
abstract：:Individual variability in sensitivity to the acute thermic effects of nicotine has been difficult to study because of methodological limitations in the use of smoking to manipulate nicotine dose. This study examined the influence of smoking history, body composition, and, in a subset of subjects, aerobic fitness and p...
journal_title：Physiology & behavior
pub_type： 临床试验,杂志文章
doi：10.1016/0031-9384(94)00381-e
更新日期：1995-06-01 00:00:00
abstract：:Compared to male secondary sexual traits, the effect of testosterone (T) on female ornaments is understudied. In particular, it is unclear whether females experience different costs of T elevation than do males and how this affects the relationship between T and ornamentation in the two sexes. I experimentally and cor...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2006.04.003
更新日期：2006-07-30 00:00:00
abstract：:Less sensitive interoception for hunger and fullness has been observed in people who consume a diet rich in saturated fat and added sugar. In this study we examined whether healthy young people who routinely consume such diets, also demonstrate less sensitive thirst interoception. Participants, varying primarily in di...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2014.11.050
更新日期：2015-02-01 00:00:00
abstract：:The conditioned taste aversion (CTA) is routinely used to assess the aversive consequences of anorexic agents, including potential pharmacological therapies for obesity. In a typical CTA paradigm, rats briefly sampling a novel tastant (e.g., saccharin) are acutely administered with toxin (e.g., lithium chloride, LiCl)...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(03)00189-6
更新日期：2003-09-01 00:00:00
abstract：:Numerous studies have established the pancreatic B-cell hormone amylin as an important anorectic peptide affecting meal-ending satiety. In the present study, we investigated the effect of a chronic infusion of the amylin antagonist AC 187 on food intake. The studies were performed using obese Zucker fa/fa rats, which ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2004.02.002
更新日期：2004-05-01 00:00:00
abstract：:In the present study we investigated the influence of body weight as defined by BMI on gustatory and olfactory perception. A total of 66 healthy adults (41 females; 25 males) participated in psychophysical measurements using the "Sniffin' Sticks" test and "Taste Strips" test. Odor thresholds as well as discrimination ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2015.01.024
更新日期：2015-04-01 00:00:00
abstract：:We have recently reported that food spillage increases during sleep deprivation in rats, which may lead to an overestimation of food intake in this condition. The objective of this study was to verify whether sleep deprivation induces an increase in gnawing behavior that could account for increased food spillage and a...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2007.08.026
更新日期：2008-01-28 00:00:00
abstract：:Rats were trained to feed each day from 10 o'clock to 12 noon. Once a week in an environment of Ta--15 degrees C, additional food was made available 16 m from a thermoneutral refuge. The additional food offered was either shortcake, meat pâté, peanut butter, Coca-cola, all of these (cafeteria), or laboratory chow. Alt...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(83)90128-2
更新日期：1983-08-01 00:00:00
abstract：:The position of substantia nigra anterior to the interaural line has been correlated with body weight in Wistar rats. A regression line y = 0.0050x + 1.36 makes it possible to locate the substantia nigra in different sized rats ranging between 140 g and 460 g. This equation is not valid for Sprague Dawley rats. The po...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(82)90075-0
更新日期：1982-02-01 00:00:00
abstract：:Sea bass, a fish species characterized by its dualistic feeding pattern, was investigated to study the synchronizing effect of light and food on the demand-feeding rhythm. Nocturnal and diurnal sea bass, both in groups and individually, were exposed to restricted-feeding (RF) and light-dark (LD) cycles of different pe...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(95)00116-z
更新日期：1995-10-01 00:00:00
abstract：:Binge eating is characterized by the consumption of a large amount of palatable food in a short period of time and is a core feature of many eating disorders. Patients with eating disorders are also known to display impairments in inhibitory control, cognition and decision-making, which may promote and maintain binge ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2019.03.005
更新日期：2019-07-01 00:00:00
abstract：:The cAMP/protein kinase A signaling pathway is negatively modulated by group II metabotropic glutamate receptors (mGluRs), and the cross-talk that occurs between these receptors may modulate learning and memory. To examine the relationship among cAMP/PKA-signaling pathway activity, group II mGluRs, and learning and me...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2003.12.010
更新日期：2004-02-01 00:00:00
abstract：:Drinking behavior produces a reduction in the unpleasant dry-mouth sensations that accompany thirst. However, it is unclear whether or not the termination of drinking behavior is governed by a mechanism that meters this process. Twenty-two participants were tested in both a "dry mouth" and a control condition. In the ...
journal_title：Physiology & behavior
pub_type： 临床试验,杂志文章
doi：10.1016/s0031-9384(99)00210-3
更新日期：2000-02-01 00:00:00
abstract：:Studies of the peripheral olfactory system of the Caribbean spiny lobster Panulirus argus and related decapod crustaceans have helped us understand mechanisms of coding of mixtures, some of which are discussed in this review. Although the number of cells in the lobster's olfactory system is much lower than in vertebra...
journal_title：Physiology & behavior
pub_type： 杂志文章,评审
doi：10.1016/s0031-9384(00)00202-x
更新日期：2000-04-01 00:00:00
abstract：:The effects of chronic social stress on behavioral sensitization to cocaine were investigated in the Syrian hamster. Adolescent animals received either 15 mg/kg i.p. of cocaine or saline twice per day for 7 consecutive days. Two weeks following the last injection (young adulthood), they were given a challenge dose of ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(02)00727-8
更新日期：2002-08-01 00:00:00
abstract：:We have previously established the rewarding value of clitoral stimulation (CLS) through the demonstration that manual, distributed, CLS induces a significant conditioned place preference (CPP) and conditioned partner preference in naïve, hormonally primed and non-hormonally primed rats. The present experiment asks wh...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2013.06.005
更新日期：2013-07-02 00:00:00
abstract：:Exploratory, locomotor and ambulatory activities were measured in nine independent groups of three inbred strains of mice (BALB/cBy, C57BL/6J and DBA/2J), at three different ages (150 days, 400 days and 750 days). The results show that for two of the three variables, the age-related changes present different patterns ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(89)90063-2
更新日期：1989-03-01 00:00:00
abstract：:To study the physiological roles of endogenous opioid peptides in drinking and feeding behaviors, the effects of water deprivation and fasting on plasma immunoreactive (IR) beta-endorphin (beta-end), IR-Antidiuretic hormone (ADH) and IR-Prolactin (Prl), pituitary IR-beta-end and IR-methionine-enkephalin (IR-Met-enk) a...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(86)90293-3
更新日期：1986-01-01 00:00:00
abstract：:Marked increases in anxiety-like responses to stress occur during pregnancy. Considerable evidence indicates that the basolateral region of the amygdala (BLA) plays an important role in mediating these types of responses. Given the crucial inhibitory influence of GABA on excitatory glutamatergic activity in the BLA, w...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2006.01.011
更新日期：2006-04-15 00:00:00
abstract：:The activity of glucose-sensitive (GS) and glucose-insensitive (GIS) neurons was recorded in the lateral hypothalamic area (LHA) of monkeys during olfactory stimulation, a conditioned alimentary bar press task, and microelectrophoretic application of catecholamines. Olfactory stimuli evoked response of 88% of the GS n...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(89)90117-0
更新日期：1989-06-01 00:00:00
