Olfactory coding in the monkey lateral hypothalamus: behavioral and neurochemical properties of odor-responding neurons.


:The activity of glucose-sensitive (GS) and glucose-insensitive (GIS) neurons was recorded in the lateral hypothalamic area (LHA) of monkeys during olfactory stimulation, a conditioned alimentary bar press task, and microelectrophoretic application of catecholamines. Olfactory stimuli evoked response of 88% of the GS neurons, and 52% of the GIS cells responded to odors. The GS neurons were more broadly tuned across odorants than the GIS cells, and their responses to various smells with distinct hedonic value were also differential. The odor-responding GS neurons were depressed during the bar press and reward periods of the task, and were mainly inhibited by dopamine. The odor-responding GIS cell activity increased in response to cue light and tone, and was facilitated by dopamine. Histological examinations disclosed topographic dissociation of the odor-responding GS and GIS cells: the former were located in more ventromedial regions than the latter. The results indicate that the GS neurons integrate multiple chemosensory inputs from both endogenous and exogenous sources in the regulation of feeding: whereas the GIS cells distinguish among fewer, more specific cues to control food acquisition behavior.


Physiol Behav


Physiology & behavior


Karádi Z,Oomura Y,Nishino H,Aou S




Has Abstract


1989-06-01 00:00:00














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    journal_title:Physiology & behavior

    pub_type: 杂志文章


    authors: Aaron M,Thorne BM

    更新日期:1975-08-01 00:00:00

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    journal_title:Physiology & behavior

    pub_type: 杂志文章


    authors: Paré WP

    更新日期:1986-01-01 00:00:00

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    journal_title:Physiology & behavior

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    authors: Zagon IS,McLaughlin PJ

    更新日期:1985-04-01 00:00:00

  • A warmer indoor environment in the evening and shorter sleep onset latency in winter: The HEIJO-KYO study.

    abstract::Difficulty in initiating sleep is an important problem because it is associated with an increased incidence of depression, diabetes, myocardial infarction, and higher all-cause mortality. Although experimental studies in controlled settings have shown that warm skin temperature of the extremities (feet and hands) befo...

    journal_title:Physiology & behavior

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    authors: Saeki K,Obayashi K,Tone N,Kurumatani N

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    journal_title:Physiology & behavior

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    authors: O'Connor CE,Matthews LR

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    journal_title:Physiology & behavior

    pub_type: 杂志文章,评审


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    authors: Sainsbury RS,Montoya CP,Westra I,Mani T

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    authors: Book CM,Millam JR,Guinan MJ,Kitchell RL

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    更新日期:1993-08-01 00:00:00

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    journal_title:Physiology & behavior

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    journal_title:Physiology & behavior

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    journal_title:Physiology & behavior

    pub_type: 杂志文章


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    journal_title:Physiology & behavior

    pub_type: 杂志文章


    authors: Tarapacki JA,Kristal MB

    更新日期:1990-02-01 00:00:00