The human microbiota associated with overall health.

abstract：:Cancer is a clinical situation caused by uncontrolled cell division and is responsible for a large number of deaths worldwide. Colchicine is a classical antimitotic, tubulin-binding agent (TBA) which is being explored for its antitumor activities, although its tubulin-binding ability leads to some toxicity toward norm...

journal_title：Critical reviews in biotechnology

authors： Dubey KK,Kumar P,Labrou NE,Shukla P

更新日期：2017-12-01 00:00:00

abstract：:In recent years, foods that contain omega-3 lipids have emerged as important promoters of human health. These lipids are essential for the functional development of the brain and retina, and reduction of the risk of cardiovascular and Alzheimer's diseases. The global market for omega-3 production, particularly docosah...

journal_title：Critical reviews in biotechnology

authors： Finco AMO,Mamani LDG,Carvalho JC,de Melo Pereira GV,Thomaz-Soccol V,Soccol CR

更新日期：2017-08-01 00:00:00

abstract：:Many algae have immense capability to sorb metals, and there is considerable potential for using them to treat wastewaters. Metal sorption involves binding on the cell surface and to intracellular ligands. The adsorbed metal is several times greater than intracellular metal. Carboxyl group is most important for metal ...

journal_title：Critical reviews in biotechnology

authors： Mehta SK,Gaur JP

更新日期：2005-07-01 00:00:00

abstract：:Endophytic microbes are present in nearly all of the plant species known to date but how they enter and flourish inside a host plant and display multiple benefits like plant growth promotion (PGP), biodegradation, and stress alleviation are still unexplored. Until now, the majority of the research has been conducted a...

journal_title：Critical reviews in biotechnology

authors： Dubey A,Malla MA,Kumar A,Dayanandan S,Khan ML

更新日期：2020-12-01 00:00:00

abstract：:Lipopolysaccharide (LPS), the major component of the outer membrane of Gram-negative bacteria, often pose a serious risk not only when delivered in the bloodstream but also in air, the environment and several industrial fields such as pharmaceutics or food. LPS is constituted of three regions; the O-specific chain, th...

journal_title：Critical reviews in biotechnology

authors： Basauri A,González-Fernández C,Fallanza M,Bringas E,Fernandez-Lopez R,Giner L,Moncalián G,de la Cruz F,Ortiz I

更新日期：2020-05-01 00:00:00

abstract：:Endotoxin is a type of pyrogen that can be found in Gram-negative bacteria. Endotoxin can form a stable interaction with other biomolecules thus making its removal difficult especially during the production of biopharmaceutical drugs. The prevention of endotoxins from contaminating biopharmaceutical products is paramo...

journal_title：Critical reviews in biotechnology

authors： Dullah EC,Ongkudon CM

更新日期：2017-03-01 00:00:00

abstract：:Corynebacterium glutamicum, a Gram-positive bacterium, has been widely used for the industrial production of amino acids, such as glutamate and lysine, for decades. Due to several characteristics - its ability to secrete properly folded and functional target proteins into culture broth, its low levels of endogenous ex...

journal_title：Critical reviews in biotechnology

authors： Liu X,Zhang W,Zhao Z,Dai X,Yang Y,Bai Z

更新日期：2017-06-01 00:00:00

abstract：:Since several decades ago, the application of pervaporation (PV) technology has been mainly aimed at the separation of different types of water-organic, organic-water and organic-organic mixtures, reaching its large-scale application in industry for the dehydration of organics. Today, the versatility and high selectiv...

journal_title：Critical reviews in biotechnology

authors： Castro-Muñoz R,Galiano F,Figoli A

更新日期：2019-11-01 00:00:00

abstract：:The role of selenium (Se) in human health and diseases has been discussed in detail in several recent reviews, with the main conclusion being that selenium deficiency is recognised as a global problem which urgently needs resolution. Since selenium content in plant-based food depends on its availability from soil, the...

journal_title：Critical reviews in biotechnology

authors： Fisinin VI,Papazyan TT,Surai PF

更新日期：2009-01-01 00:00:00

abstract：:Protein glycosylation is post-translational modification (PTM) which is important for pharmacokinetics and immunogenicity of recombinant glycoprotein therapeutics. As a result of variations in monosaccharide composition, glycosidic linkages and glycan branching, glycosylation introduces considerable complexity and het...

journal_title：Critical reviews in biotechnology

authors： Goh JB,Ng SK

更新日期：2018-09-01 00:00:00

abstract：:Mushrooms have become increasingly important as a reliable food source. They have also been recognized as an important source of bioactive compounds of high nutritional and medicinal values. The nucleobases, nucleosides and nucleotides found in mushrooms play important roles in the regulation of various physiological ...

journal_title：Critical reviews in biotechnology

authors： Phan CW,Wang JK,Cheah SC,Naidu M,David P,Sabaratnam V

更新日期：2018-08-01 00:00:00

abstract：:Bacteriocins produced by lactic acid bacteria (LAB) are well-recognized for their potential as natural food preservatives. These antimicrobial peptides usually do not change the sensorial properties of food products and can be used in combination with traditional preservation methods to ensure microbial stability. In ...

journal_title：Critical reviews in biotechnology

authors： Barbosa AAT,Mantovani HC,Jain S

更新日期：2017-11-01 00:00:00

abstract：:Endocrine-disrupting compounds (EDCs) can interfere with endocrine systems and bio-accumulate through the food chain and even decrease biodiversity in contaminated areas. This review discusses a critical overview of recent research progress in the biotransformation of EDCs (including polychlorinated biphenyl and nonyl...

journal_title：Critical reviews in biotechnology

authors： Huang D,Guo X,Peng Z,Zeng G,Xu P,Gong X,Deng R,Xue W,Wang R,Yi H,Liu C

更新日期：2018-08-01 00:00:00

abstract：:Many reporter genes, such as gfp, gusA, and lacZ, are widely used for research into plants, animals, and microorganisms. Reporter genes, which offer high levels of sensitivity and convenience of detection, have been utilized in transgenic technology, promoter analysis, drug screening, and other areas. Directed molecul...

journal_title：Critical reviews in biotechnology

authors： Xiong AS,Peng RH,Zhuang J,Davies J,Zhang J,Yao QH

更新日期：2012-06-01 00:00:00

abstract：:Briskly evolving phytopathogens are dire threats to our food supplies and threaten global food security. From the recent advances made toward high-throughput sequencing technologies, understanding of pathogenesis and effector biology, and plant innate immunity, translation of these means into new control tools is bein...

journal_title：Critical reviews in biotechnology

authors： Nejat N,Rookes J,Mantri NL,Cahill DM

更新日期：2017-03-01 00:00:00

abstract：:Nitrilases are widely distributed in nature and are able to hydrolyze nitriles into their corresponding carboxylic acids and ammonia. In industry, nitrilases have been used as green biocatalysts for the production of high value-added products. To date, biocatalysts are considered to be important alternatives to chemic...

journal_title：Critical reviews in biotechnology

authors： Shen JD,Cai X,Liu ZQ,Zheng YG

更新日期：2021-02-01 00:00:00

abstract：:A large number of rice agronomic traits are complex, multi factorial and polygenic. As the mechanisms and genes determining grain size and yield are largely unknown, the identification of regulatory genes related to grain development remains a preeminent approach in rice genetic studies and breeding programs. Genes re...

journal_title：Critical reviews in biotechnology

authors： Azizi P,Osman M,Hanafi MM,Sahebi M,Rafii MY,Taheri S,Harikrishna JA,Tarinejad AR,Mat Sharani S,Yusuf MN

更新日期：2019-11-01 00:00:00

abstract：:Small RNAs (sRNA) are reported to play pivotal roles in the epigenetic and post-transcriptional regulation of gene expression during growth, development, and stress response in plants. Recently, the involvement of two different classes of sRNAs namely, miRNAs (microRNAs), and siRNAs (small interfering RNAs) in biotic ...

journal_title：Critical reviews in biotechnology

authors： Prasad A,Sharma N,Muthamilarasan M,Rana S,Prasad M

更新日期：2019-06-01 00:00:00

abstract：:Microbial diversity provides an immense reservoir of functions and supports key steps in maintaining ecosystem balance through matter decomposition processes and nutrient recycling. The use of microorganisms for biomolecule production is now common, but often involves single-strain cultures. In this review, we highlig...

journal_title：Critical reviews in biotechnology

authors： Jobard M,Pessiot J,Nouaille R,Fonty G,Sime-Ngando T

更新日期：2017-02-01 00:00:00

abstract：:Cross-linked enzyme aggregate (CLEA) technology has been regarded as an effective carrier-free immobilization method. This method is very attractive due to its simplicity and robustness, as well as for the possibility of using the crude enzyme extract and the opportunity to co-immobilize multiple different enzymes. Th...

journal_title：Critical reviews in biotechnology

authors： Cui JD,Jia SR

更新日期：2015-03-01 00:00:00

abstract：:Microorganisms have the tendency to accumulate at interfaces through the release of extracellular polymeric substances to form aggregates such as films or flocs. This physical association leads to different modes of interactions among cells and the subsequent development of functionally and metabolically diverse conso...

journal_title：Critical reviews in biotechnology

authors： Srivastava A,Seo SH,Ko SR,Ahn CY,Oh HM

更新日期：2018-12-01 00:00:00

abstract：:Alginate has been widely used in various applications since its first extraction. What makes this biopolymer useful is its high biocompatibility and humid gelation conditions. Both of these features bring it into prominence as an ideal immobilization material. However, there are some complicated aspects of cell immobi...

journal_title：Critical reviews in biotechnology

authors： Selimoglu SM,Elibol M

更新日期：2010-06-01 00:00:00

abstract：:Aerobic granules are the potential tools to develop modern wastewater treatment technologies with improved nutrient removal efficiency. These granules have several promising advantages over conventional activated sludge-based wastewater treatment processes. This technology has the potential of reducing the infrastruct...

journal_title：Critical reviews in biotechnology

authors： Sarma SJ,Tay JH

更新日期：2018-11-01 00:00:00

abstract：:Biocatalysis in non-aqueous media has undergone tremendous development during the last decade, and numerous reactions have been introduced and optimized for synthetic applications. In contrast to aqueous enzymology, biotransformations in organic solvents offer unique industrially attractive advantages, such as: drasti...

journal_title：Critical reviews in biotechnology

authors： Castro GR,Knubovets T

更新日期：2003-01-01 00:00:00

abstract：:Calf rennet, which consists of over 90% chymosin, is commonly used in cheese industries for the curdling of milk. Various animal, plant and microbial sources have been exploited as possible alternatives to calf rennet. The coagulating properties of the enzymatic preparations (coagulants) from these sources differ in t...

journal_title：Critical reviews in biotechnology

authors： Kumar A,Grover S,Sharma J,Batish VK

更新日期：2010-12-01 00:00:00

abstract：:Recombinant DNA technology enables the creation of well-defined alterations in the genetic material of an organism. Methods to manipulate recombinant DNA in the filamentous fungi (a group of microorganisms that includes species of academic as well as commercial interest) have recently been developed. This has been the...

journal_title：Critical reviews in biotechnology

authors： Rambosek J,Leach J

更新日期：1987-01-01 00:00:00

abstract：:The beneficial effects of endophytes on plant growth are important for agricultural ecosystems because they reduce the need for fertilizers and decrease soil and water pollution while compensating for environmental perturbations. Endophytic fungi are a novel source of bioactive secondary metabolites; moreover, recentl...

journal_title：Critical reviews in biotechnology

authors： Khan AL,Hussain J,Al-Harrasi A,Al-Rawahi A,Lee IJ

更新日期：2015-03-01 00:00:00

abstract：:Vitamin C (L-ascorbic acid; AsA) is the major soluble antioxidant found in plants and is also an essential component of human nutrition. Although numerous biotechnological methods have been exploited to increase its yield, pressures such as commercial competition and environmental concerns make it urgent to find a new...

journal_title：Critical reviews in biotechnology

authors： Zhang L,Wang Z,Xia Y,Kai G,Chen W,Tang K

更新日期：2007-07-01 00:00:00

abstract：:Metabolic engineering is crucial in the development of production strains for platform chemicals, pharmaceuticals and biomaterials from renewable resources. The central carbon metabolism (CCM) of heterotrophs plays an essential role in the conversion of biomass to the cellular building blocks required for growth. Yet,...

journal_title：Critical reviews in biotechnology

authors： Kopp D,Sunna A

更新日期：2020-11-01 00:00:00

abstract：:Microorganisms produce biosurfactant (BS)/bioemulsifier (BE) with wide structural and functional diversity which consequently results in the adoption of different techniques to investigate these diverse amphiphilic molecules. This review aims to compile information on different microbial screening methods, surface act...

journal_title：Critical reviews in biotechnology

authors： Satpute SK,Banpurkar AG,Dhakephalkar PK,Banat IM,Chopade BA

更新日期：2010-06-01 00:00:00