A review on the nucleic acid constituents in mushrooms: nucleobases, nucleosides and nucleotides.

abstract：:The emergence of new gene-editing technologies is profoundly transforming human therapeutics, agriculture, and industrial biotechnology. Advances in clustered regularly interspaced short palindromic repeats (CRISPR) have created a fertile environment for mass-scale manufacturing of cost-effective products ranging from...

journal_title：Critical reviews in biotechnology

authors： Brinegar K,K Yetisen A,Choi S,Vallillo E,Ruiz-Esparza GU,Prabhakar AM,Khademhosseini A,Yun SH

更新日期：2017-11-01 00:00:00

abstract：:Metabolic engineering is crucial in the development of production strains for platform chemicals, pharmaceuticals and biomaterials from renewable resources. The central carbon metabolism (CCM) of heterotrophs plays an essential role in the conversion of biomass to the cellular building blocks required for growth. Yet,...

journal_title：Critical reviews in biotechnology

authors： Kopp D,Sunna A

更新日期：2020-11-01 00:00:00

abstract：:Innovation holds the potential for economic prosperity. Biotechnology (BT) has proved to be a viable vehicle for the development and utilization of technologies, which has brought not only advances to society, but also career opportunities to nation-states that have enabling conditions. In this review, we assess the c...

journal_title：Critical reviews in biotechnology

authors： Dettenhofer M,Ondrejovič M,Slavica A,Kurtanjek Ž,Tapaloaga D,Rodian Tapaloaga P,Kapur Pojskić L,Durmić-Pašić A,Begović J,Nedović V,Dundar M,Gartland KMA,Miertuš S

更新日期：2019-02-01 00:00:00

abstract：:Phytoremediation uses plants and associated microbes to remove pollutants from the environment and is considered a promising bioremediation method. Compared with well-described single contaminant treatments, the number of studies reporting phytoremediation of soil mixed pollutants has increased recently. Endophytes, i...

journal_title：Critical reviews in biotechnology

authors： He W,Megharaj M,Wu CY,Subashchandrabose SR,Dai CC

更新日期：2020-02-01 00:00:00

abstract：:Filamentous fungi comprise an abundance of gene clusters that encode high-value metabolites, whereas affluent gene clusters remain silent during laboratory conditions. Complex cellular metabolism further limits these metabolite yields. Therefore, diverse strategies such as genetic engineering and chemical mutagenesis ...

journal_title：Critical reviews in biotechnology

authors： Deng H,Bai Y,Fan TP,Zheng X,Cai Y

更新日期：2020-03-01 00:00:00

abstract：:The beneficial effects of endophytes on plant growth are important for agricultural ecosystems because they reduce the need for fertilizers and decrease soil and water pollution while compensating for environmental perturbations. Endophytic fungi are a novel source of bioactive secondary metabolites; moreover, recentl...

journal_title：Critical reviews in biotechnology

authors： Khan AL,Hussain J,Al-Harrasi A,Al-Rawahi A,Lee IJ

更新日期：2015-03-01 00:00:00

abstract：:Bacteriocins produced by lactic acid bacteria (LAB) are well-recognized for their potential as natural food preservatives. These antimicrobial peptides usually do not change the sensorial properties of food products and can be used in combination with traditional preservation methods to ensure microbial stability. In ...

journal_title：Critical reviews in biotechnology

authors： Barbosa AAT,Mantovani HC,Jain S

更新日期：2017-11-01 00:00:00

abstract：:Aerobic granules are the potential tools to develop modern wastewater treatment technologies with improved nutrient removal efficiency. These granules have several promising advantages over conventional activated sludge-based wastewater treatment processes. This technology has the potential of reducing the infrastruct...

journal_title：Critical reviews in biotechnology

authors： Sarma SJ,Tay JH

更新日期：2018-11-01 00:00:00

abstract：:Fungal biopolymers have gained considerable attention from the scientific community for various applications due to their biological and physicochemical properties. The wide applications in several areas, especially in the food industry as a bioemulsifier and in the agricultural area as a biosurfactant, have expanded ...

journal_title：Critical reviews in biotechnology

authors： Luft L,Confortin TC,Todero I,Zabot GL,Mazutti MA

更新日期：2020-12-01 00:00:00

abstract：:Endotoxin is a type of pyrogen that can be found in Gram-negative bacteria. Endotoxin can form a stable interaction with other biomolecules thus making its removal difficult especially during the production of biopharmaceutical drugs. The prevention of endotoxins from contaminating biopharmaceutical products is paramo...

journal_title：Critical reviews in biotechnology

authors： Dullah EC,Ongkudon CM

更新日期：2017-03-01 00:00:00

abstract：:Microbial diversity provides an immense reservoir of functions and supports key steps in maintaining ecosystem balance through matter decomposition processes and nutrient recycling. The use of microorganisms for biomolecule production is now common, but often involves single-strain cultures. In this review, we highlig...

journal_title：Critical reviews in biotechnology

authors： Jobard M,Pessiot J,Nouaille R,Fonty G,Sime-Ngando T

更新日期：2017-02-01 00:00:00

abstract：:Hydrodynamic cavitation (HC) is a process technology with potential for application in different areas including environmental, food processing, and biofuels production. Although HC is an undesirable phenomenon for hydraulic equipment, the net energy released during this process is enough to accelerate certain chemica...

journal_title：Critical reviews in biotechnology

authors： Terán Hilares R,Ramos L,da Silva SS,Dragone G,Mussatto SI,Santos JCD

更新日期：2018-06-01 00:00:00

abstract：:Starting with a brief history of solid-state fermentation (SSF), major aspects of SSF are reviewed, which include factors affecting SSF, biomass, fermentors, modeling, industrial microbial enzymes, organic acids, secondary metabolites, and bioremediation. Physico-chemical and environmental factors such as inoculum typ...

journal_title：Critical reviews in biotechnology

authors： Krishna C

更新日期：2005-01-01 00:00:00

abstract：:Prokaryotic expression systems are superior in producing valuable recombinant proteins, enzymes and therapeutic products. Conventional microbial technology is evolving gradually and amalgamated with advanced technologies in order to give rise to improved processes for the production of metabolites, recombinant biophar...

journal_title：Critical reviews in biotechnology

authors： Gupta SK,Shukla P

更新日期：2016-12-01 00:00:00

abstract：:The 2014 Ebola outbreak, the largest recorded, took us largely unprepared, with no available vaccine or specific treatment. In this context, the World Health Organization declared that the humanitarian use of experimental therapies against Ebola Virus (EBOV) is ethical. In particular, an experimental treatment consist...

journal_title：Critical reviews in biotechnology

authors： González-González E,Alvarez MM,Márquez-Ipiña AR,Trujillo-de Santiago G,Rodríguez-Martínez LM,Annabi N,Khademhosseini A

更新日期：2017-02-01 00:00:00

abstract：:The role of selenium (Se) in human health and diseases has been discussed in detail in several recent reviews, with the main conclusion being that selenium deficiency is recognised as a global problem which urgently needs resolution. Since selenium content in plant-based food depends on its availability from soil, the...

journal_title：Critical reviews in biotechnology

authors： Fisinin VI,Papazyan TT,Surai PF

更新日期：2009-01-01 00:00:00

abstract：:Erythritol is a natural sweetener commonly used in the food and pharmaceutical industries. Produced by microorganisms as an osmoprotectant, it is an ideal sucrose substitute for diabetics or overweight persons due to its almost zero calorie content. Currently, erythritol is produced on an industrial scale through the ...

journal_title：Critical reviews in biotechnology

authors： Rzechonek DA,Dobrowolski A,Rymowicz W,Mirończuk AM

更新日期：2018-06-01 00:00:00

abstract：:Triacylglycerol (TAG) serves as an energy reservoir and phospholipids as build blocks of biomembrane to support plant life. They also provide human with foods and nutrients. Multi-compartmentalized biosynthesis, trafficking or cross-membrane transport of lipid intermediates or precursors and their regulatory mechanism...

journal_title：Critical reviews in biotechnology

authors： Manan S,Chen B,She G,Wan X,Zhao J

更新日期：2017-08-01 00:00:00

abstract：:With more and more plastics being employed in human lives and increasing pressure being placed on capacities available for plastic waste disposal, the need for biodegradable plastics and biodegradation of plastic wastes has assumed increasing importance in the last few years. This review looks at the technological adv...

journal_title：Critical reviews in biotechnology

authors： Zheng Y,Yanful EK,Bassi AS

更新日期：2005-10-01 00:00:00

abstract：:Affinity tags are vital tools for the production of high-throughput recombinant proteins. Several affinity tags, such as the hexahistidine tag, maltose-binding protein, streptavidin-binding peptide tag, calmodulin-binding peptide, c-Myc tag, glutathione S-transferase and FLAG tag, have been introduced for recombinant ...

journal_title：Critical reviews in biotechnology

authors： Soleimanpour S,Hassannia T,Motiee M,Amini AA,Rezaee SA

更新日期：2017-05-01 00:00:00

abstract：:Terpenes are natural products with a remarkable diversity in their chemical structures and they hold a significant market share commercially owing to their distinct applications. These potential molecules are usually derived from terrestrial plants, marine and microbial sources. In vitro production of terpenes using p...

journal_title：Critical reviews in biotechnology

authors： Paramasivan K,Mutturi S

更新日期：2017-12-01 00:00:00

abstract：:Vitamin C (L-ascorbic acid; AsA) is the major soluble antioxidant found in plants and is also an essential component of human nutrition. Although numerous biotechnological methods have been exploited to increase its yield, pressures such as commercial competition and environmental concerns make it urgent to find a new...

journal_title：Critical reviews in biotechnology

authors： Zhang L,Wang Z,Xia Y,Kai G,Chen W,Tang K

更新日期：2007-07-01 00:00:00

abstract：:Over the past few decades, a considerable attention has been focused on the microbial polyhydroxyalkanoates (PHAs) owing to its multifaceted properties, i.e. biodegradability, biocompatibility, non-toxicity and thermo-plasticity. This article presents a critical review of the foregoing research, current trends and fut...

journal_title：Critical reviews in biotechnology

authors： Masood F,Yasin T,Hameed A

更新日期：2015-01-01 00:00:00

abstract：:Triterpenoid saponins are structurally diverse secondary metabolites. They are the main active ingredient of many medicinal plants and have a wide range of pharmacological effects. Traditional production of triterpenoid saponins, directly extracted from cultivated plants, cannot meet the rapidly growing demand of phar...

journal_title：Critical reviews in biotechnology

authors： Yao L,Wang J,He J,Huang L,Gao W

更新日期：2021-01-20 00:00:00

abstract：:Salt-tolerant plants grow in a wide variety of saline habitats, from coastal regions, salt marshes and mudflats to inland deserts, salt flats and steppes. Halophytes living in these extreme environments have to deal with frequent changes in salinity level. This can be done by developing adaptive responses including th...

journal_title：Critical reviews in biotechnology

authors： Ksouri R,Ksouri WM,Jallali I,Debez A,Magné C,Hiroko I,Abdelly C

更新日期：2012-12-01 00:00:00

abstract：:Due to serious eutrophication in water bodies, nitrogen removal has become a critical stage for wastewater treatment plants (WWTPs) over past decades. Conventional biological nitrogen removal processes are based on nitrification and denitrification (N/DN), and are suffering from several major drawbacks, including subs...

journal_title：Critical reviews in biotechnology

authors： Liu T,Hu S,Guo J

更新日期：2019-08-01 00:00:00

abstract：:Corynebacterium glutamicum, a Gram-positive bacterium, has been widely used for the industrial production of amino acids, such as glutamate and lysine, for decades. Due to several characteristics - its ability to secrete properly folded and functional target proteins into culture broth, its low levels of endogenous ex...

journal_title：Critical reviews in biotechnology

authors： Liu X,Zhang W,Zhao Z,Dai X,Yang Y,Bai Z

更新日期：2017-06-01 00:00:00

abstract：:Many algae have immense capability to sorb metals, and there is considerable potential for using them to treat wastewaters. Metal sorption involves binding on the cell surface and to intracellular ligands. The adsorbed metal is several times greater than intracellular metal. Carboxyl group is most important for metal ...

journal_title：Critical reviews in biotechnology

authors： Mehta SK,Gaur JP

更新日期：2005-07-01 00:00:00

abstract：:Second generation biofuel production depends on lignocellulosic (LC) biomass transformation into simple sugars and their subsequent fermentation into alcohols. However, the main obstacle in this process is the efficient breakdown of the recalcitrant cellulose to sugar monomers. Hence, efficient feedstock pretreatment ...

journal_title：Critical reviews in biotechnology

authors： Portillo Mdel C,Saadeddin A

更新日期：2015-01-01 00:00:00

abstract：:Microorganisms have the tendency to accumulate at interfaces through the release of extracellular polymeric substances to form aggregates such as films or flocs. This physical association leads to different modes of interactions among cells and the subsequent development of functionally and metabolically diverse conso...

journal_title：Critical reviews in biotechnology

authors： Srivastava A,Seo SH,Ko SR,Ahn CY,Oh HM

更新日期：2018-12-01 00:00:00