Abstract:
:Nitrilases are widely distributed in nature and are able to hydrolyze nitriles into their corresponding carboxylic acids and ammonia. In industry, nitrilases have been used as green biocatalysts for the production of high value-added products. To date, biocatalysts are considered to be important alternatives to chemical catalysts due to increasing environmental problems and resource scarcity. This review provides an overview of recent advances of nitrilases in aspects of distribution, enzyme screening, molecular structure and catalytic mechanism, protein engineering, and their potential applications in industry.
journal_name
Crit Rev Biotechnoljournal_title
Critical reviews in biotechnologyauthors
Shen JD,Cai X,Liu ZQ,Zheng YGdoi
10.1080/07388551.2020.1827367subject
Has Abstractpub_date
2021-02-01 00:00:00pages
72-93issue
1eissn
0738-8551issn
1549-7801journal_volume
41pub_type
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