Abstract:
:We assembled a collection of 73 Capnocytophaga canimorsus isolates obtained from blood cultures taken from patients treated at Helsinki University Hospital (Helsinki, Finland) during 2000-2017. We serotyped these isolates by PCR and Western blot and attempted to correlate pathogen serovar with patient characteristics. Our analyses showed, in agreement with previous research, that 3 C. canimorsus serovars (A-C) caused most (91.8%) human infections, despite constituting only 7.6% of isolates found in dogs. The 3 fatalities that occurred in our cohort were equally represented by these serovars. We found 2 untypeable isolates, which we designated serovars J and K. We did not detect an association between serovar and disease severity, immune status, alcohol abuse, or smoking status, but dog bites occurred more frequently among patients infected with non-A-C serovars. Future research is needed to confirm serovar virulence and develop strategies to reduce risk for these infections in humans.
journal_name
Emerg Infect Disjournal_title
Emerging infectious diseasesauthors
Hess E,Renzi F,Karhunen P,Dol M,Lefèvre A,Antikainen J,Carlier E,Hästbacka J,Cornelis GRdoi
10.3201/eid2412.172060subject
Has Abstractpub_date
2018-12-01 00:00:00pages
2195-2201issue
12eissn
1080-6040issn
1080-6059journal_volume
24pub_type
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