tDCS over the left inferior frontal cortex improves speech production in aphasia.

Abstract:

:In this study, we investigated the combined effect of transcranial direct current stimulation (tDCS) and an intensive Conversational therapy treatment on discourse skills in 12 persons with chronic aphasia. Six short video clips depicting everyday life contexts were prepared. Three videoclips were used to elicit spontaneous conversation during treatment. The remaining three were presented only before and after the therapy. Participants were prompted to talk about the contents of each videoclip while stimulated with tDCS (20 min 1 mA) over the left hemisphere in three conditions: anodic tDCS over the Broca's area, anodic tDCS over the Wernicke's area, and a sham condition. Each experimental condition was performed for 10 consecutive daily sessions with 14 days of intersession interval. After stimulation over Broca's area, the participants produced more Content Units, verbs and sentences than in the remaining two conditions. Importantly, this improvement was still detectable 1 month after the end of treatment and its effects were generalized also to the three videoclips that had been administered at the beginning and at the end of the therapy sessions. In conclusion, anodic tDCS applied over the left Broca's area together with an intensive "Conversational Therapy" treatment improves informative speech in persons with chronic aphasia. We believe that positive tDCS effects may be further extended to other language domains, such as the recovery of speech production.

journal_name

Front Hum Neurosci

authors

Marangolo P,Fiori V,Calpagnano MA,Campana S,Razzano C,Caltagirone C,Marini A

doi

10.3389/fnhum.2013.00539

subject

Has Abstract

pub_date

2013-09-06 00:00:00

pages

539

issn

1662-5161

journal_volume

7

pub_type

杂志文章
  • Paradoxical dopaminergic drug effects in extraversion: dose- and time-dependent effects of sulpiride on EEG theta activity.

    abstract::Dopaminergic drugs frequently produce paradoxical effects depending on baseline performance levels, genotype, or personality traits. The present study for the first time aimed to specify the mechanisms underlying such opposite effects using the following recently reported scenario as an example: depending on the perso...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2013.00117

    authors: Chavanon ML,Wacker J,Stemmler G

    更新日期:2013-04-08 00:00:00

  • Effects of arousal on cognitive control: empirical tests of the conflict-modulated Hebbian-learning hypothesis.

    abstract::An increasing number of empirical phenomena that were previously interpreted as a result of cognitive control, turn out to reflect (in part) simple associative-learning effects. A prime example is the proportion congruency effect, the finding that interference effects (such as the Stroop effect) decrease as the propor...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2014.00023

    authors: Brown SB,van Steenbergen H,Kedar T,Nieuwenhuis S

    更新日期:2014-01-30 00:00:00

  • Comparing Aging and Fitness Effects on Brain Anatomy.

    abstract::Recent studies suggest that cardiorespiratory fitness (CRF) mitigates the brain's atrophy typically associated with aging, via a variety of beneficial mechanisms. One could argue that if CRF is generally counteracting the negative effects of aging, the same regions that display the greatest age-related volumetric loss...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2016.00286

    authors: Fletcher MA,Low KA,Boyd R,Zimmerman B,Gordon BA,Tan CH,Schneider-Garces N,Sutton BP,Gratton G,Fabiani M

    更新日期:2016-06-28 00:00:00

  • A Multi-Target Motor Imagery Training Using Bimodal EEG-fMRI Neurofeedback: A Pilot Study in Chronic Stroke Patients.

    abstract::Traditional rehabilitation techniques present limitations and the majority of patients show poor 1-year post-stroke recovery. Thus, Neurofeedback (NF) or Brain-Computer-Interface applications for stroke rehabilitation purposes are gaining increased attention. Indeed, NF has the potential to enhance volitional control ...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2020.00037

    authors: Lioi G,Butet S,Fleury M,Bannier E,Lécuyer A,Bonan I,Barillot C

    更新日期:2020-02-18 00:00:00

  • Neural Patterns of the Implicit Association Test.

    abstract::The Implicit Association Test (IAT) is a reaction time based categorization task that measures the differential associative strength between bipolar targets and evaluative attribute concepts as an approach to indexing implicit beliefs or biases. An open question exists as to what exactly the IAT measures, and here EEG...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2015.00605

    authors: Healy GF,Boran L,Smeaton AF

    更新日期:2015-11-24 00:00:00

  • Effects of the 2-Repeat Allele of the DRD4 Gene on Neural Networks Associated With the Prefrontal Cortex in Children With ADHD.

    abstract::Objective: Genetic variation, especially polymorphism of the dopamine D4 receptor gene (DRD4), has been linked to deficits in self-regulation and executive functions and to attention deficit hyperactivity disorder (ADHD), and is related to the structural and functional integrity of the default mode network (DMN), the ...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2018.00279

    authors: Qian A,Tao J,Wang X,Liu H,Ji L,Yang C,Ye Q,Chen C,Li J,Cheng J,Wang M,Zhao K

    更新日期:2018-07-12 00:00:00

  • Functional Imaging of the Human Brainstem during Somatosensory Input and Autonomic Output.

    abstract::Over the past half a century, many investigations in experimental animal have explored the functional roles of specific regions in the brainstem. Despite the accumulation of a considerable body of knowledge in, primarily, anesthetized preparations, relatively few studies have explored brainstem function in awake human...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章,评审

    doi:10.3389/fnhum.2013.00569

    authors: Henderson LA,Macefield VG

    更新日期:2013-09-17 00:00:00

  • Dysregulated left inferior parietal activity in schizophrenia and depression: functional connectivity and characterization.

    abstract::The inferior parietal cortex (IPC) is a heterogeneous region that is known to be involved in a multitude of diverse different tasks and processes, though its contribution to these often-complex functions is yet poorly understood. In a previous study we demonstrated that patients with depression failed to deactivate th...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2013.00268

    authors: Müller VI,Cieslik EC,Laird AR,Fox PT,Eickhoff SB

    更新日期:2013-06-12 00:00:00

  • The Impact of Monaural Beat Stimulation on Anxiety and Cognition.

    abstract::Application of auditory beat stimulation has been speculated to provide a promising new tool with which to alleviate symptoms of anxiety and to enhance cognition. In spite of reportedly similar EEG effects of binaural and monaural beats, data on behavioral effects of monaural beats are still lacking. Therefore, we exa...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2017.00251

    authors: Chaieb L,Wilpert EC,Hoppe C,Axmacher N,Fell J

    更新日期:2017-05-15 00:00:00

  • An Electromyographic Analysis of the Effects of Cognitive Fatigue on Online and Anticipatory Action Control.

    abstract::Cognitive fatigue is a problem for the safety of critical systems (e.g., aircraft) as it can lead to accidents, especially during unexpected events. In order to determine the extent to which it disrupts adaptive capabilities, we evaluated its effect on online and anticipatory control. Despite numerous studies conducte...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2020.615046

    authors: Salomone M,Burle B,Fabre L,Berberian B

    更新日期:2021-01-11 00:00:00

  • Reduced Pain Sensation and Reduced BOLD Signal in Parietofrontal Networks during Religious Prayer.

    abstract::Previous studies suggest that religious prayer can alter the experience of pain via expectation mechanisms. While brain processes related to other types of top-down modulation of pain have been studied extensively, no research has been conducted on the potential effects of active religious coping. Here, we aimed at in...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2017.00337

    authors: Elmholdt EM,Skewes J,Dietz M,Møller A,Jensen MS,Roepstorff A,Wiech K,Jensen TS

    更新日期:2017-06-28 00:00:00

  • Temporal dynamics of attentional selection in adult male carriers of the fragile X premutation allele and adult controls.

    abstract::Carriers of the fragile X premutation allele (fXPCs) have an expanded CGG trinucleotide repeat size within the FMR1 gene and are at increased risk of developing fragile x-associated tremor/ataxia syndrome (FXTAS). Previous research has shown that male fXPCs with FXTAS exhibit cognitive decline, predominantly in execut...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2015.00037

    authors: Wong LM,Tassone F,Rivera SM,Simon TJ

    更新日期:2015-02-05 00:00:00

  • The Dancing Brain: Structural and Functional Signatures of Expert Dance Training.

    abstract::Dance - as a ritual, therapy, and leisure activity - has been known for thousands of years. Today, dance is increasingly used as therapy for cognitive and neurological disorders such as dementia and Parkinson's disease. Surprisingly, the effects of dance training on the healthy young brain are not well understood desp...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2017.00566

    authors: Burzynska AZ,Finc K,Taylor BK,Knecht AM,Kramer AF

    更新日期:2017-11-27 00:00:00

  • Neurofeminism and feminist neurosciences: a critical review of contemporary brain research.

    abstract::To date, feminist approaches to neurosciences have evaluated the debates surrounding practices of knowledge production within and research results of contemporary brain research. Consequently, neurofeminist scholars have critically examined gendered impacts of neuroscientific research. Feminist neuroscientists also de...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章,评审

    doi:10.3389/fnhum.2014.00546

    authors: Schmitz S,Höppner G

    更新日期:2014-07-25 00:00:00

  • Mindfulness-induced selflessness: a MEG neurophenomenological study.

    abstract::Contemporary philosophical and neurocognitive studies of the self have dissociated two distinct types of self-awareness: a "narrative" self-awareness (NS) weaving together episodic memory, future planning and self-evaluation into a coherent self-narrative and identity, and a "minimal" self-awareness (MS) focused on pr...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2013.00582

    authors: Dor-Ziderman Y,Berkovich-Ohana A,Glicksohn J,Goldstein A

    更新日期:2013-09-24 00:00:00

  • Developmental aspects of cortical excitability and inhibition in depressed and healthy youth: an exploratory study.

    abstract:OBJECTIVES:The objective of this post-hoc exploratory analysis was to examine the relationship between age and measures of cortical excitability and inhibition. METHODS:Forty-six participants (24 with major depressive disorder and 22 healthy controls) completed MT, SICI, ICF, and CSP testing in a cross-sectional proto...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2014.00669

    authors: Croarkin PE,Nakonezny PA,Lewis CP,Zaccariello MJ,Huxsahl JE,Husain MM,Kennard BD,Emslie GJ,Daskalakis ZJ

    更新日期:2014-09-02 00:00:00

  • Enhanced Functional Connectivity between the Bilateral Primary Motor Cortices after Acupuncture at Yanglingquan (GB34) in Right-Hemispheric Subcortical Stroke Patients: A Resting-State fMRI Study.

    abstract::Increasing neuroimaging researches in stroke rehabilitation had revealed the neural mechanisms of rehabilitation therapy. However, little was known about the neural mechanisms of acupuncture therapy in subcortical stroke patients. The aim of this study was to investigate the changes of functional connectivity (FC) bet...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2017.00178

    authors: Ning Y,Li K,Fu C,Ren Y,Zhang Y,Liu H,Cui F,Zou Y

    更新日期:2017-04-10 00:00:00

  • The Immediate and Sustained Positive Effects of Meditation on Resilience Are Mediated by Changes in the Resting Brain.

    abstract::While recent studies have explored the maintenance of the effect of meditation on stress resilience, the underlying neural mechanisms have not yet been investigated. The present study conducted a highly controlled residential study of a 4-day meditation intervention to investigate the brain functional changes and long...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2019.00101

    authors: Kwak S,Lee TY,Jung WH,Hur JW,Bae D,Hwang WJ,Cho KIK,Lim KO,Kim SY,Park HY,Kwon JS

    更新日期:2019-03-26 00:00:00

  • Attention in a bayesian framework.

    abstract::The behavioral phenomena of sensory attention are thought to reflect the allocation of a limited processing resource, but there is little consensus on the nature of the resource or why it should be limited. Here we argue that a fundamental bottleneck emerges naturally within Bayesian models of perception, and use this...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2012.00100

    authors: Whiteley L,Sahani M

    更新日期:2012-06-14 00:00:00

  • Sex Differences in Gray Matter Volume of the Right Anterior Hippocampus Explain Sex Differences in Three-Dimensional Mental Rotation.

    abstract::Behavioral studies have reported that males perform better than females in 3-dimensional (3D) mental rotation. Given the important role of the hippocampus in spatial processing, the present study investigated whether structural differences in the hippocampus could explain the sex difference in 3D mental rotation. Resu...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2016.00580

    authors: Wei W,Chen C,Dong Q,Zhou X

    更新日期:2016-11-15 00:00:00

  • Action video game play and transfer of navigation and spatial cognition skills in adolescents who are blind.

    abstract::For individuals who are blind, navigating independently in an unfamiliar environment represents a considerable challenge. Inspired by the rising popularity of video games, we have developed a novel approach to train navigation and spatial cognition skills in adolescents who are blind. Audio-based Environment Simulator...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2014.00133

    authors: Connors EC,Chrastil ER,Sánchez J,Merabet LB

    更新日期:2014-03-11 00:00:00

  • Synchronous Neural Oscillation Between the Right Inferior Fronto-Parietal Cortices Contributes to Body Awareness.

    abstract::The right inferior fronto-parietal network monitors the current status of the musculoskeletal system and builds-up and updates our postural model. The kinesthetic illusion induced by tendon vibration has been utilized in experiments on the modulation of body awareness. The right inferior fronto-parietal cortices activ...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2019.00330

    authors: Takeuchi N,Sudo T,Oouchida Y,Mori T,Izumi SI

    更新日期:2019-09-24 00:00:00

  • Neural Activity and Decoding of Action Observation Using Combined EEG and fNIRS Measurement.

    abstract::In a social world, observing the actions of others is fundamental to understanding what they are doing, as well as their intentions and feelings. Studies of the neural basis and decoding of action observation are important for understanding action-related processes and have implications for cognitive, social neuroscie...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2019.00357

    authors: Ge S,Wang P,Liu H,Lin P,Gao J,Wang R,Iramina K,Zhang Q,Zheng W

    更新日期:2019-10-15 00:00:00

  • Origins Matter: Culture Impacts Cognitive Testing in Parkinson's Disease.

    abstract::Cognitive decline is common in Parkinson's disease (PD), and precise cognitive assessment is important for diagnosis, prognosis, and treatment. To date, there are no studies in PD investigating cultural bias on neuropsychological tests. Clinical practice in multicultural societies such as, Toronto Canada where nearly ...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2019.00269

    authors: Statucka M,Cohn M

    更新日期:2019-08-08 00:00:00

  • Effector-Specific Characterization of Brain Dynamics in Manual vs. Oculomotor Go/NoGo Tasks.

    abstract::Motor inhibitory control (IC), the ability to suppress unwanted actions, has been previously shown to rely on domain-general IC processes that are involved in a wide range of IC tasks. Nevertheless, the existence of effector-specific regions and activation patterns that would differentiate manual vs. oculomotor respon...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2020.600667

    authors: Simonet M,Ruggeri P,Barral J

    更新日期:2020-12-03 00:00:00

  • Extrastriate visual cortex reorganizes despite sequential bilateral occipital stroke: implications for vision recovery.

    abstract::The extent of visual cortex reorganization following injury remains controversial. We report serial functional magnetic resonance imaging (fMRI) data from a patient with sequential posterior circulation strokes occurring 3 weeks apart, compared with data from an age-matched healthy control subject. At 8 days following...

    journal_title:Frontiers in human neuroscience

    pub_type:

    doi:10.3389/fnhum.2015.00224

    authors: Brodtmann A,Puce A,Darby D,Donnan G

    更新日期:2015-04-28 00:00:00

  • Transient Global Amnesia: An Electrophysiological Disorder Based on Cortical Spreading Depression-Transient Global Amnesia Model.

    abstract::Transient global amnesia (TGA) is a benign memory disorder with etiologies that have been debated for a long time. The prevalence of stressful events before a TGA attack makes it hard to overlook these precipitating factors, given that stress has the potential to organically effect the brain. Cortical spreading depres...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2020.602496

    authors: Ding X,Peng D

    更新日期:2020-12-08 00:00:00

  • Longitudinal Diffusion Tensor Imaging-Based Assessment of Tract Alterations: An Application to Amyotrophic Lateral Sclerosis.

    abstract::Objective: The potential of magnetic resonance imaging (MRI) as a technical biomarker for cerebral microstructural alterations in neurodegenerative diseases is under investigation. In this study, a framework for the longitudinal analysis of diffusion tensor imaging (DTI)-based mapping was applied to the assessment of ...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2017.00567

    authors: Baldaranov D,Khomenko A,Kobor I,Bogdahn U,Gorges M,Kassubek J,Müller HP

    更新日期:2017-12-05 00:00:00

  • An Event Related Field Study of Rapid Grammatical Plasticity in Adult Second-Language Learners.

    abstract::The present study used magnetoencephalography (MEG) to investigate how Spanish adult learners of Basque respond to morphosyntactic violations after a short period of training on a small fragment of Basque grammar. Participants (n = 17) were exposed to violation and control phrases in three phases (pretest, training, g...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2017.00012

    authors: Bastarrika A,Davidson DJ

    更新日期:2017-01-24 00:00:00

  • Influences of Head Motion Regression on High-Frequency Oscillation Amplitudes of Resting-State fMRI Signals.

    abstract::High-frequency oscillations (HFOs, >0.1 Hz) of resting-state fMRI (rs-fMRI) signals have received much attention in recent years. Denoising is critical for HFO studies. Previous work indicated that head motion (HM) has remarkable influences on a variety of rs-fMRI metrics, but its influences on rs-fMRI HFOs are still ...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2016.00243

    authors: Yuan BK,Zang YF,Liu DQ

    更新日期:2016-05-26 00:00:00