Sex Differences in Gray Matter Volume of the Right Anterior Hippocampus Explain Sex Differences in Three-Dimensional Mental Rotation.

Abstract:

:Behavioral studies have reported that males perform better than females in 3-dimensional (3D) mental rotation. Given the important role of the hippocampus in spatial processing, the present study investigated whether structural differences in the hippocampus could explain the sex difference in 3D mental rotation. Results showed that after controlling for brain size, males had a larger anterior hippocampus, whereas females had a larger posterior hippocampus. Gray matter volume (GMV) of the right anterior hippocampus was significantly correlated with 3D mental rotation score. After controlling GMV of the right anterior hippocampus, sex difference in 3D mental rotation was no longer significant. These results suggest that the structural difference between males' and females' right anterior hippocampus was a neurobiological substrate for the sex difference in 3D mental rotation.

journal_name

Front Hum Neurosci

authors

Wei W,Chen C,Dong Q,Zhou X

doi

10.3389/fnhum.2016.00580

subject

Has Abstract

pub_date

2016-11-15 00:00:00

pages

580

issn

1662-5161

journal_volume

10

pub_type

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