Recovery of resting brain connectivity ensuing mild traumatic brain injury.

Abstract:

:Brains reveal amplified plasticity as they recover from an injury. We aimed to define time dependent plasticity changes in patients recovering from mild traumatic brain injury (mTBI). Twenty-five subjects with mild head injury were longitudinally evaluated within 36 h, 3 and 6 months using resting state functional connectivity (RSFC). Region of interest (ROI) based connectivity differences over time within the patient group and in comparison with a healthy control group were analyzed at p < 0.005. We found 33 distinct ROI pairs that revealed significant changes in their connectivity strength with time. Within 3 months, the majority of the ROI pairs had decreased connectivity in mTBI population, which increased and became comparable to healthy controls at 6 months. Within this diffuse decreased connectivity in the first 3 months, there were also few regions with increased connections. This hyper connectivity involved the salience network and default mode network within 36 h, and lingual, inferior frontal and fronto-parietal networks at 3 months. Our findings in a fairly homogenous group of patients with mTBI evaluated during the 6 month window of recovery defines time varying brain connectivity changes as the brain recovers from an injury. A majority of these changes were seen in the frontal and parietal lobes between 3 and 6 months after injury. Hyper connectivity of several networks supported normal recovery in the first 6 months and it remains to be seen in future studies whether this can predict an early and efficient recovery of brain function.

journal_name

Front Hum Neurosci

authors

Bharath RD,Munivenkatappa A,Gohel S,Panda R,Saini J,Rajeswaran J,Shukla D,Bhagavatula ID,Biswal BB

doi

10.3389/fnhum.2015.00513

subject

Has Abstract

pub_date

2015-09-22 00:00:00

pages

513

issn

1662-5161

journal_volume

9

pub_type

杂志文章
  • Quadri-stability of a spatially ambiguous auditory illusion.

    abstract::In addition to vision, audition plays an important role in sound localization in our world. One way we estimate the motion of an auditory object moving towards or away from us is from changes in volume intensity. However, the human auditory system has unequally distributed spatial resolution, including difficulty dist...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2014.01060

    authors: Bainbridge CM,Bainbridge WA,Oliva A

    更新日期:2015-01-15 00:00:00

  • Coupling brain-machine interfaces with cortical stimulation for brain-state dependent stimulation: enhancing motor cortex excitability for neurorehabilitation.

    abstract::Motor recovery after stroke is an unsolved challenge despite intensive rehabilitation training programs. Brain stimulation techniques have been explored in addition to traditional rehabilitation training to increase the excitability of the stimulated motor cortex. This modulation of cortical excitability augments the ...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2014.00122

    authors: Gharabaghi A,Kraus D,Leão MT,Spüler M,Walter A,Bogdan M,Rosenstiel W,Naros G,Ziemann U

    更新日期:2014-03-05 00:00:00

  • Early Neural Markers of Implicit Attitudes: N170 Modulated by Intergroup and Evaluative Contexts in IAT.

    abstract::The Implicit Association Test (IAT) is the most popular measure to evaluate implicit attitudes. Nevertheless, its neural correlates are not yet fully understood. We examined event related potentials (ERPs) in response to face- and word processing while indigenous and non-indigenous participants performed an IAT displa...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2010.00188

    authors: Ibáñez A,Gleichgerrcht E,Hurtado E,González R,Haye A,Manes FF

    更新日期:2010-10-19 00:00:00

  • Attractiveness Modulates Neural Processing of Infant Faces Differently in Males and Females.

    abstract::Consistent attention and proper processing of infant faces by adults are essential for infant survival. Previous behavioral studies showed gender differences in processing infant cues (e.g., crying, laughing or facial attractiveness) and more importantly, the efforts invested in nurturing offspring. The underlying neu...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2017.00551

    authors: Yin L,Fan M,Lin L,Sun D,Wang Z

    更新日期:2017-11-14 00:00:00

  • The experience of mathematical beauty and its neural correlates.

    abstract::Many have written of the experience of mathematical beauty as being comparable to that derived from the greatest art. This makes it interesting to learn whether the experience of beauty derived from such a highly intellectual and abstract source as mathematics correlates with activity in the same part of the emotional...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2014.00068

    authors: Zeki S,Romaya JP,Benincasa DM,Atiyah MF

    更新日期:2014-02-13 00:00:00

  • The Principle of Inverse Effectiveness in Audiovisual Speech Perception.

    abstract::We assessed how synchronous speech listening and lipreading affects speech recognition in acoustic noise. In simple audiovisual perceptual tasks, inverse effectiveness is often observed, which holds that the weaker the unimodal stimuli, or the poorer their signal-to-noise ratio, the stronger the audiovisual benefit. S...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2019.00335

    authors: van de Rijt LPH,Roye A,Mylanus EAM,van Opstal AJ,van Wanrooij MM

    更新日期:2019-09-26 00:00:00

  • Contagious itch: what we know and what we would like to know.

    abstract::All humans experience itch in the course of their life. Even a discussion on the topic of itch or seeing people scratch can evoke the desire to scratch. These events are coined "contagious itch" and are very common. We and others have shown that videos showing people scratching and pictures of affected skin or insects...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章,评审

    doi:10.3389/fnhum.2015.00057

    authors: Schut C,Grossman S,Gieler U,Kupfer J,Yosipovitch G

    更新日期:2015-02-11 00:00:00

  • Examining neural correlates of skill acquisition in a complex videogame training program.

    abstract::Acquisition of complex skills is a universal feature of human behavior that has been conceptualized as a process that starts with intense resource dependency, requires effortful cognitive control, and ends in relative automaticity on the multi-faceted task. The present study examined the effects of different theoretic...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2012.00115

    authors: Prakash RS,De Leon AA,Mourany L,Lee H,Voss MW,Boot WR,Basak C,Fabiani M,Gratton G,Kramer AF

    更新日期:2012-05-15 00:00:00

  • The ethology of empathy: a taxonomy of real-world targets of need and their effect on observers.

    abstract::Empathy is inherently interpersonal, but the majority of research has only examined observers. Targets of need have been largely held constant through hypothetical and fictionalized depictions of sympathetic distress and need. In the real world, people's response to life stressors varies widely-from stoicism to resili...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2013.00488

    authors: Preston SD,Hofelich AJ,Stansfield RB

    更新日期:2013-08-22 00:00:00

  • "Brain MR spectroscopy in autism spectrum disorder-the GABA excitatory/inhibitory imbalance theory revisited".

    abstract::Magnetic resonance spectroscopy (MRS) from voxels placed in the left anterior cingulate cortex (ACC) was measured from 14 boys with Autism Spectrum Disorder (ASD) and 24 gender and age-matched typically developing (TD) control group. Our main aims were to compare the concentration of γ-aminobutyric acid (GABA) between...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2015.00365

    authors: Brix MK,Ersland L,Hugdahl K,Grüner R,Posserud MB,Hammar Å,Craven AR,Noeske R,Evans CJ,Walker HB,Midtvedt T,Beyer MK

    更新日期:2015-06-22 00:00:00

  • Motivational salience and genetic variability of dopamine D2 receptor expression interact in the modulation of interference processing.

    abstract::Dopamine has been implicated in the fine-tuning of complex cognitive and motor function and also in the anticipation of future rewards. This dual function of dopamine suggests that dopamine might be involved in the generation of active motivated behavior. The DRD2 TaqIA polymorphism of the dopamine D2 receptor gene (r...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2013.00250

    authors: Richter A,Richter S,Barman A,Soch J,Klein M,Assmann A,Libeau C,Behnisch G,Wüstenberg T,Seidenbecher CI,Schott BH

    更新日期:2013-06-05 00:00:00

  • Attachment Representations and Brain Asymmetry during the Processing of Autobiographical Emotional Memories in Late Adolescence.

    abstract::Frontal and parietal asymmetries have repeatedly been shown to be related to specific functional mechanisms involved in emotion regulation. From a developmental perspective, attachment representations based on experiences with the caregiver are theorized to serve regulatory functions and influence how individuals deal...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2016.00644

    authors: Kungl MT,Leyh R,Spangler G

    更新日期:2016-12-26 00:00:00

  • Linking neuroscientific research on decision making to the educational context of novice students assigned to a multiple-choice scientific task involving common misconceptions about electrical circuits.

    abstract::Functional magnetic resonance imaging was used to identify the brain-based mechanisms of uncertainty and certainty associated with answers to multiple-choice questions involving common misconceptions about electric circuits. Twenty-two scientifically novice participants (humanities and arts college students) were aske...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2014.00014

    authors: Potvin P,Turmel E,Masson S

    更新日期:2014-01-27 00:00:00

  • Different Resting State EEG Features in Children from Switzerland and Saudi Arabia.

    abstract::Background: Cultural neuroscience is an emerging research field concerned with studying the influences of different cultures on brain anatomy and function. In this study, we examined whether different cultural or genetic influences might influence the resting state electroencephalogram (EEG) in young children (mean ag...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2016.00559

    authors: Alahmadi N,Evdokimov SA,Kropotov YJ,Müller AM,Jäncke L

    更新日期:2016-11-02 00:00:00

  • Magnitude Processing in the Brain: An fMRI Study of Time, Space, and Numerosity as a Shared Cortical System.

    abstract::Continuous dimensions, such as time, space, and numerosity, have been suggested to be subserved by common neurocognitive mechanisms. Neuroimaging studies that have investigated either one or two dimensions simultaneously have consistently identified neural correlates in the parietal cortex of the brain. However, studi...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2016.00500

    authors: Skagerlund K,Karlsson T,Träff U

    更新日期:2016-10-05 00:00:00

  • Bi-Dimensional Approach Based on Transfer Learning for Alcoholism Pre-disposition Classification via EEG Signals.

    abstract::Recent statistics have shown that the main difficulty in detecting alcoholism is the unreliability of the information presented by patients with alcoholism; this factor confusing the early diagnosis and it can reduce the effectiveness of treatment. However, electroencephalogram (EEG) exams can provide more reliable da...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2020.00365

    authors: Zhang H,Silva FHS,Ohata EF,Medeiros AG,Rebouças Filho PP

    更新日期:2020-09-18 00:00:00

  • 5 Hz repetitive transcranial magnetic stimulation over the ipsilesional sensory cortex enhances motor learning after stroke.

    abstract::Sensory feedback is critical for motor learning, and thus to neurorehabilitation after stroke. Whether enhancing sensory feedback by applying excitatory repetitive transcranial magnetic stimulation (rTMS) over the ipsilesional primary sensory cortex (IL-S1) might enhance motor learning in chronic stroke has yet to be ...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2014.00143

    authors: Brodie SM,Meehan S,Borich MR,Boyd LA

    更新日期:2014-03-21 00:00:00

  • Transcranial Magnetic Stimulation Reveals Executive Control Dissociation in the Rostral Prefrontal Cortex.

    abstract::Although previous studies have shown that the rostral prefrontal cortex (rPFC) plays a crucial role in executive tasks, the various functions of the rPFC in the humans are still understudied. Here we used transcranial magnetic stimulation (TMS) with continuous theta burst stimulation (cTBS) to interfere with the execu...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2017.00464

    authors: He W,Fan C,Li L

    更新日期:2017-09-22 00:00:00

  • Methodological Problems With Online Concussion Testing.

    abstract::Reaction time testing is widely used in online computerized concussion assessments, and most concussion studies utilizing the metric have demonstrated varying degrees of difference between concussed and non-concussed individuals. The problem with most of these online concussion assessments is that they predominantly r...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2020.509091

    authors: Holden J,Francisco E,Tommerdahl A,Lensch R,Kirsch B,Zai L,Pearce AJ,Favorov OV,Dennis RG,Tommerdahl M

    更新日期:2020-10-01 00:00:00

  • Relationship of the Acoustic Startle Response and Its Modulation to Adaptive and Maladaptive Behaviors in Typically Developing Children and Those With Autism Spectrum Disorders: A Pilot Study.

    abstract::Background: Autism spectrum disorder (ASD) is associated with persistent impairments in adaptive functioning across multiple domains of daily life. Thus, investigation of the biological background of both adaptive and maladaptive behaviors may shed light on developing effective interventions for improving social adapt...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2019.00005

    authors: Ebishima K,Takahashi H,Stickley A,Nakahachi T,Sumiyoshi T,Kamio Y

    更新日期:2019-01-22 00:00:00

  • Directional organization and shape formation: new illusions and Helmholtz's Square.

    abstract::According to Helmholtz's Square illusion, a square appears wider when it is filled with vertical lines and higher when filled with horizontal lines (Helmholtz von, 1866). Recently, Pinna (2010a) demonstrated that the grouping of small squares on the basis of the similarity principle influences also perception of their...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2015.00092

    authors: Pinna B

    更新日期:2015-03-03 00:00:00

  • Comparing Aging and Fitness Effects on Brain Anatomy.

    abstract::Recent studies suggest that cardiorespiratory fitness (CRF) mitigates the brain's atrophy typically associated with aging, via a variety of beneficial mechanisms. One could argue that if CRF is generally counteracting the negative effects of aging, the same regions that display the greatest age-related volumetric loss...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2016.00286

    authors: Fletcher MA,Low KA,Boyd R,Zimmerman B,Gordon BA,Tan CH,Schneider-Garces N,Sutton BP,Gratton G,Fabiani M

    更新日期:2016-06-28 00:00:00

  • Different influences on lexical priming for integrative, thematic, and taxonomic relations.

    abstract::Word pairs may be integrative (i.e., combination of two concepts into one meaningful entity; e.g., fruit-cake), thematically related (i.e., connected in time and place; e.g., party-cake), and/or taxonomically related (i.e., shared features and category co-members; e.g., muffin-cake). Using participant ratings and comp...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2012.00205

    authors: Jones LL,Golonka S

    更新日期:2012-07-11 00:00:00

  • Corrigendum: Who Deserves My Trust? Cue-Elicited Feedback Negativity Tracks Reputation Learning in Repeated Social Interactions.

    abstract::[This corrects the article DOI: 10.3389/fnhum.2017.00307.]. ...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章,已发布勘误

    doi:10.3389/fnhum.2019.00083

    authors: Li D,Meng L,Ma Q

    更新日期:2019-03-06 00:00:00

  • Effects of Age on Long Term Memory for Degraded Speech.

    abstract::Prior research suggests that acoustical degradation impacts encoding of items into memory, especially in elderly subjects. We here aimed to investigate whether acoustically degraded items that are initially encoded into memory are more prone to forgetting as a function of age. Young and old participants were tested wi...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2016.00473

    authors: Thiel CM,Özyurt J,Nogueira W,Puschmann S

    更新日期:2016-09-21 00:00:00

  • Optic ataxia as a model to investigate the role of the posterior parietal cortex in visually guided action: evidence from studies of patient M.H.

    abstract::Optic ataxia is a neuropsychological disorder that affects the ability to interact with objects presented in the visual modality following either unilateral or bilateral lesions of the posterior parietal cortex (PPC). Patients with optic ataxia fail to reach accurately for objects, particularly when they are presented...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2013.00336

    authors: Cavina-Pratesi C,Connolly JD,Milner AD

    更新日期:2013-07-16 00:00:00

  • Diffusion tensor imaging studies on arcuate fasciculus in stroke patients: a review.

    abstract::Aphasia is one of the most common and devastating sequelae of stroke. The arcuate fasciculus (AF), an important neural tract for language function, connects Broca's and Wernicke's areas. In this review article, previous diffusion tensor imaging (DTI) studies on the AF in stroke patients were reviewed with regard to th...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章,评审

    doi:10.3389/fnhum.2013.00749

    authors: Jang SH

    更新日期:2013-11-01 00:00:00

  • Neuro-Immunity Controls Obesity-Induced Pain.

    abstract::The prevalence of obesity skyrocketed over the past decades to become a significant public health problem. Obesity is recognized as a low-grade inflammatory disease and is linked with several comorbidities such as diabetes, circulatory disease, common neurodegenerative diseases, as well as chronic pain. Adipocytes are...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章,评审

    doi:10.3389/fnhum.2020.00181

    authors: Eichwald T,Talbot S

    更新日期:2020-06-09 00:00:00

  • Decreased small-world functional network connectivity and clustering across resting state networks in schizophrenia: an fMRI classification tutorial.

    abstract::Functional network connectivity (FNC) is a method of analyzing the temporal relationship of anatomical brain components, comparing the synchronicity between patient groups or conditions. We use functional-connectivity measures between independent components to classify between Schizophrenia patients and healthy contro...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2013.00520

    authors: Anderson A,Cohen MS

    更新日期:2013-09-02 00:00:00

  • Comparison of the Working Memory Load in N-Back and Working Memory Span Tasks by Means of EEG Frequency Band Power and P300 Amplitude.

    abstract::According to theoretical accounts, both, N-back and complex span tasks mainly require working memory (WM) processing. In contrast, simple span tasks conceptually mainly require WM storage. Thus, conceptually, an N-back task and a complex span task share more commonalities as compared to a simple span task. In the curr...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2017.00006

    authors: Scharinger C,Soutschek A,Schubert T,Gerjets P

    更新日期:2017-01-25 00:00:00