5 Hz repetitive transcranial magnetic stimulation over the ipsilesional sensory cortex enhances motor learning after stroke.

Abstract:

:Sensory feedback is critical for motor learning, and thus to neurorehabilitation after stroke. Whether enhancing sensory feedback by applying excitatory repetitive transcranial magnetic stimulation (rTMS) over the ipsilesional primary sensory cortex (IL-S1) might enhance motor learning in chronic stroke has yet to be investigated. The present study investigated the effects of 5 Hz rTMS over IL-S1 paired with skilled motor practice on motor learning, hemiparetic cutaneous somatosensation, and motor function. Individuals with unilateral chronic stroke were pseudo-randomly divided into either Active or Sham 5 Hz rTMS groups (n = 11/group). Following stimulation, both groups practiced a Serial Tracking Task (STT) with the hemiparetic arm; this was repeated for 5 days. Performance on the STT was quantified by response time, peak velocity, and cumulative distance tracked at baseline, during the 5 days of practice, and at a no-rTMS retention test. Cutaneous somatosensation was measured using two-point discrimination. Standardized sensorimotor tests were performed to assess whether the effects might generalize to impact hemiparetic arm function. The active 5 Hz rTMS + training group demonstrated significantly greater improvements in STT performance {response time [F (1, 286.04) = 13.016, p < 0.0005], peak velocity [F (1, 285.95) = 4.111, p = 0.044], and cumulative distance [F (1, 285.92) = 4.076, p = 0.044]} and cutaneous somatosensation [F (1, 21.15) = 8.793, p = 0.007] across all sessions compared to the sham rTMS + training group. Measures of upper extremity motor function were not significantly different for either group. Our preliminary results suggest that, when paired with motor practice, 5 Hz rTMS over IL-S1 enhances motor learning related change in individuals with chronic stroke, potentially as a consequence of improved cutaneous somatosensation, however no improvement in general upper extremity function was observed.

journal_name

Front Hum Neurosci

authors

Brodie SM,Meehan S,Borich MR,Boyd LA

doi

10.3389/fnhum.2014.00143

subject

Has Abstract

pub_date

2014-03-21 00:00:00

pages

143

issn

1662-5161

journal_volume

8

pub_type

杂志文章
  • Scene complexity: influence on perception, memory, and development in the medial temporal lobe.

    abstract::Regions in the medial temporal lobe (MTL) and prefrontal cortex (PFC) are involved in memory formation for scenes in both children and adults. The development in children and adolescents of successful memory encoding for scenes has been associated with increased activation in PFC, but not MTL, regions. However, eviden...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2010.00021

    authors: Chai XJ,Ofen N,Jacobs LF,Gabrieli JD

    更新日期:2010-03-05 00:00:00

  • Social Cues Alter Implicit Motor Learning in a Serial Reaction Time Task.

    abstract::Learning is a central ability for human development. Many skills we learn, such as language, are learned through observation or imitation in social contexts. Likewise, many skills are learned implicitly, that is, without an explicit intent to learn and without full awareness of the acquired knowledge. Here, we asked w...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2018.00197

    authors: Geiger A,Cleeremans A,Bente G,Vogeley K

    更新日期:2018-05-14 00:00:00

  • Anterior Cingulate Cortico-Hippocampal Dysconnectivity in Unaffected Relatives of Schizophrenia Patients: A Stochastic Dynamic Causal Modeling Study.

    abstract::Familial risk plays a significant role in the etiology of schizophrenia (SZ). Many studies using neuroimaging have demonstrated structural and functional alterations in relatives of SZ patients, with significant results found in diverse brain regions involving the anterior cingulate cortex (ACC), caudate, dorsolateral...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2016.00383

    authors: Xi YB,Li C,Cui LB,Liu J,Guo F,Li L,Liu TT,Liu K,Chen G,Xi M,Wang HN,Yin H

    更新日期:2016-07-27 00:00:00

  • Tactile priming modulates the activation of the fronto-parietal circuit during tactile angle match and non-match processing: an fMRI study.

    abstract::The repetition of a stimulus task reduces the neural activity within certain cortical regions responsible for working memory (WM) processing. Although previous evidence has shown that repeated vibrotactile stimuli reduce the activation in the ventrolateral prefrontal cortex, whether the repeated tactile spatial stimul...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2014.00926

    authors: Yang J,Yu Y,Kunita A,Huang Q,Wu J,Sawamoto N,Fukuyama H

    更新日期:2014-12-15 00:00:00

  • High-Resolution MR Imaging of the Human Brainstem In vivo at 7 Tesla.

    abstract::The human brainstem, which comprises a multitude of axonal nerve fibers and nuclei, plays an important functional role in the human brain. Depicting its anatomy non-invasively with high spatial resolution may thus in turn help to better relate normal and pathological anatomical variations to medical conditions as well...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2013.00710

    authors: Deistung A,Schäfer A,Schweser F,Biedermann U,Güllmar D,Trampel R,Turner R,Reichenbach JR

    更新日期:2013-10-29 00:00:00

  • Content-specific coordination of listeners' to speakers' EEG during communication.

    abstract::Cognitive neuroscience has recently begun to extend its focus from the isolated individual mind to two or more individuals coordinating with each other. In this study we uncover a coordination of neural activity between the ongoing electroencephalogram (EEG) of two people-a person speaking and a person listening. The ...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2012.00266

    authors: Kuhlen AK,Allefeld C,Haynes JD

    更新日期:2012-10-01 00:00:00

  • The development of an RDoC-based treatment program for adolescent depression: "Training for Awareness, Resilience, and Action" (TARA).

    abstract::Major depressive disorder (MDD) is one of the current leading causes of disability worldwide. Adolescence is a vulnerable period for the onset of depression, with MDD affecting 8-20% of all youth. Traditional treatment methods have not been sufficiently effective to slow the increasing prevalence of adolescent depress...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2014.00630

    authors: Henje Blom E,Duncan LG,Ho TC,Connolly CG,LeWinn KZ,Chesney M,Hecht FM,Yang TT

    更新日期:2014-08-19 00:00:00

  • The effects of acute aerobic activity on cognition and cross-domain transfer to eating behavior.

    abstract::Prior studies have demonstrated that a single session of aerobic exercise can enhance cognitive functioning; specifically, the inhibition facet of executive function (EF). Additionally, previous research has demonstrated that inhibitory abilities are essential for effective dietary self-control. However, it is current...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2014.00267

    authors: Lowe CJ,Hall PA,Vincent CM,Luu K

    更新日期:2014-04-30 00:00:00

  • Towards a Multimodal Model of Cognitive Workload Through Synchronous Optical Brain Imaging and Eye Tracking Measures.

    abstract::Recent advances in neuroimaging technologies have rendered multimodal analysis of operators' cognitive processes in complex task settings and environments increasingly more practical. In this exploratory study, we utilized optical brain imaging and mobile eye tracking technologies to investigate the behavioral and neu...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2019.00375

    authors: İşbilir E,Çakır MP,Acartürk C,Tekerek AŞ

    更新日期:2019-10-23 00:00:00

  • Self-awareness, self-regulation, and self-transcendence (S-ART): a framework for understanding the neurobiological mechanisms of mindfulness.

    abstract::Mindfulness-as a state, trait, process, type of meditation, and intervention has proven to be beneficial across a diverse group of psychological disorders as well as for general stress reduction. Yet, there remains a lack of clarity in the operationalization of this construct, and underlying mechanisms. Here, we provi...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2012.00296

    authors: Vago DR,Silbersweig DA

    更新日期:2012-10-25 00:00:00

  • Corrigendum: Who Deserves My Trust? Cue-Elicited Feedback Negativity Tracks Reputation Learning in Repeated Social Interactions.

    abstract::[This corrects the article DOI: 10.3389/fnhum.2017.00307.]. ...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章,已发布勘误

    doi:10.3389/fnhum.2019.00083

    authors: Li D,Meng L,Ma Q

    更新日期:2019-03-06 00:00:00

  • Efficacy and Brain Imaging Correlates of an Immersive Motor Imagery BCI-Driven VR System for Upper Limb Motor Rehabilitation: A Clinical Case Report.

    abstract::To maximize brain plasticity after stroke, a plethora of rehabilitation strategies have been explored. These include the use of intensive motor training, motor-imagery (MI), and action-observation (AO). Growing evidence of the positive impact of virtual reality (VR) techniques on recovery following stroke has been sho...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2019.00244

    authors: Vourvopoulos A,Jorge C,Abreu R,Figueiredo P,Fernandes JC,Bermúdez I Badia S

    更新日期:2019-07-11 00:00:00

  • Children with Spastic Cerebral Palsy Experience Difficulties Adjusting Their Gait Pattern to Weight Added to the Waist, While Typically Developing Children Do Not.

    abstract::The prevalence of childhood overweight and obesity is increasing in the last decades, also in children with Cerebral Palsy (CP). Even though it has been established that an increase in weight can have important negative effects on gait in healthy adults and children, it has not been investigated what the effect is of ...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2016.00657

    authors: Meyns P,Van Gestel L,Bar-On L,Goudriaan M,Wambacq H,Aertbeliën E,Bruyninckx H,Molenaers G,De Cock P,Ortibus E,Desloovere K

    更新日期:2016-12-23 00:00:00

  • Electrocorticographic Activation within Human Auditory Cortex during Dialog-Based Language and Cognitive Testing.

    abstract::Current models of cortical speech and language processing include multiple regions within the temporal lobe of both hemispheres. Human communication, by necessity, involves complex interactions between regions subserving speech and language processing with those involved in more general cognitive functions. To assess ...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2016.00202

    authors: Nourski KV,Steinschneider M,Rhone AE

    更新日期:2016-05-04 00:00:00

  • Calibrating Doppler imaging of preterm intracerebral circulation using a microvessel flow phantom.

    abstract:INTRODUCTION:Preterm infants are born during critical stages of brain development, in which the adaptive capacity of the fetus to extra-uterine environment is limited. Inadequate brain perfusion has been directly linked to preterm brain damage. Advanced high-frequency ultrasound probes and processing algorithms allow v...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2014.01068

    authors: Camfferman FA,Ecury-Goossen GM,La Roche JE,de Jong N,van 't Leven W,Vos HJ,Verweij MD,Nasserinejad K,Cools F,Govaert P,Dudink J

    更新日期:2015-01-13 00:00:00

  • Comparing Aging and Fitness Effects on Brain Anatomy.

    abstract::Recent studies suggest that cardiorespiratory fitness (CRF) mitigates the brain's atrophy typically associated with aging, via a variety of beneficial mechanisms. One could argue that if CRF is generally counteracting the negative effects of aging, the same regions that display the greatest age-related volumetric loss...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2016.00286

    authors: Fletcher MA,Low KA,Boyd R,Zimmerman B,Gordon BA,Tan CH,Schneider-Garces N,Sutton BP,Gratton G,Fabiani M

    更新日期:2016-06-28 00:00:00

  • Relationship of the Acoustic Startle Response and Its Modulation to Adaptive and Maladaptive Behaviors in Typically Developing Children and Those With Autism Spectrum Disorders: A Pilot Study.

    abstract::Background: Autism spectrum disorder (ASD) is associated with persistent impairments in adaptive functioning across multiple domains of daily life. Thus, investigation of the biological background of both adaptive and maladaptive behaviors may shed light on developing effective interventions for improving social adapt...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2019.00005

    authors: Ebishima K,Takahashi H,Stickley A,Nakahachi T,Sumiyoshi T,Kamio Y

    更新日期:2019-01-22 00:00:00

  • Neural correlates of moral and non-moral emotion in female psychopathy.

    abstract::This study presents the first neuroimaging investigation of female psychopathy in an incarcerated population. Prior studies have found that male psychopathy is associated with reduced limbic and paralimbic activation when processing emotional stimuli and making moral judgments. The goal of this study was to investigat...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2014.00741

    authors: Harenski CL,Edwards BG,Harenski KA,Kiehl KA

    更新日期:2014-09-25 00:00:00

  • Sensitivity to Auditory Spectral Width in the Fetus and Infant - An fMEG Study.

    abstract::Auditory change detection is crucial for the development of the auditory system and a prerequisite for language development. In neonates, stimuli with broad spectral width like white noise (WN) elicit the highest response compared to pure tone and combined tone stimuli. In the current study we addressed for the first ...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2013.00917

    authors: Muenssinger J,Matuz T,Schleger F,Draganova R,Weiss M,Kiefer-Schmidt I,Wacker-Gussmann A,Govindan RB,Lowery CL,Eswaran H,Preissl H

    更新日期:2013-12-31 00:00:00

  • Incorporation of Multiple-Days Information to Improve the Generalization of EEG-Based Emotion Recognition Over Time.

    abstract::Current studies have got a series of satisfying accuracies in EEG-based emotion classification, but most of the classifiers used in previous studies are totally time-limited. To produce generalizable results, the emotion classifier should be stable over days, in which the day-to-day variations of EEG should be appropr...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2018.00267

    authors: Liu S,Chen L,Guo D,Liu X,Sheng Y,Ke Y,Xu M,An X,Yang J,Ming D

    更新日期:2018-06-29 00:00:00

  • Does richness lose its luster? Effects of extensive practice on semantic richness in visual word recognition.

    abstract::Previous studies have reported facilitatory effects of semantic richness on word recognition (e.g., Yap et al., 2012). These effects suggest that word meaning is an important contributor to lexical decision task (LDT) performance, but what are the effects of repeated LDT practice on these semantic contributions? The c...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2012.00234

    authors: Hargreaves IS,Pexman PM

    更新日期:2012-08-14 00:00:00

  • Methodological lessons in neurophenomenology: Review of a baseline study and recommendations for research approaches.

    abstract::Neurophenomenological (NP) methods integrate objective and subjective data in ways that retain the statistical power of established disciplines (like cognitive science) while embracing the value of first-person reports of experience. The present paper positions neurophenomenology as an approach that pulls from traditi...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2013.00608

    authors: Bockelman P,Reinerman-Jones L,Gallagher S

    更新日期:2013-10-10 00:00:00

  • Electrical Stimulation Mapping of Brain Function: A Comparison of Subdural Electrodes and Stereo-EEG.

    abstract::Despite technological and interpretative advances, the non-invasive modalities used for pre-surgical evaluation of patients with drug-resistant epilepsy (DRE), fail to generate a concordant anatomo-electroclinical hypothesis for the location of the seizure onset zone in many patients. This requires chronic monitoring ...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2020.611291

    authors: Grande KM,Ihnen SKZ,Arya R

    更新日期:2020-12-07 00:00:00

  • Abnormal asymmetry of brain connectivity in schizophrenia.

    abstract::Recently, a growing body of data has revealed that beyond a dysfunction of connectivity among different brain areas in schizophrenia patients (SCZ), there is also an abnormal asymmetry of functional connectivity compared with healthy subjects. The loss of the cerebral torque and the abnormalities of gyrification, with...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章,评审

    doi:10.3389/fnhum.2014.01010

    authors: Ribolsi M,Daskalakis ZJ,Siracusano A,Koch G

    更新日期:2014-12-22 00:00:00

  • What Can the Organization of the Brain's Default Mode Network Tell us About Self-Knowledge?

    abstract::Understanding ourselves has been a fundamental topic for psychologists and philosophers alike. In this paper we review the evidence linking specific brain structures to self-reflection. The brain regions most associated with self-reflection are the posterior cingulate and medial prefrontal (mPFC) cortices, together kn...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2013.00391

    authors: Moran JM,Kelley WM,Heatherton TF

    更新日期:2013-07-17 00:00:00

  • Individual structural differences in left inferior parietal area are associated with schoolchildrens' arithmetic scores.

    abstract::Arithmetic skill is of critical importance for academic achievement, professional success and everyday life, and childhood is the key period to acquire this skill. Neuroimaging studies have identified that left parietal regions are a key neural substrate for representing arithmetic skill. Although the relationship bet...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2013.00844

    authors: Li Y,Hu Y,Wang Y,Weng J,Chen F

    更新日期:2013-12-06 00:00:00

  • Hypnosis as neurophenomenology.

    abstract::Hypnosis research binds phenomenology and neuroscience. Here we show how recent evidence probing the impact of hypnosis and suggestion can inform and advance a neurophenomenological approach. In contrast to meditative practices that involve lengthy and intensive training, hypnosis induces profound alterations in subje...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2013.00469

    authors: Lifshitz M,Cusumano EP,Raz A

    更新日期:2013-08-15 00:00:00

  • Behind the Scenes of Developmental Language Disorder: Time to Call Neuropsychology Back on Stage.

    abstract::Although the Developmental Language Disorder (DLD), also known as Specific Language Impairment in children has been the focus of unceasing scientific attention for decades, the nature and mechanisms of this disorder remain unclear. Most importantly, we still cannot reliably identify children requiring urgent intervent...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章,评审

    doi:10.3389/fnhum.2018.00517

    authors: Tomas E,Vissers C

    更新日期:2019-01-09 00:00:00

  • Probabilistic atlases of default mode, executive control and salience network white matter tracts: an fMRI-guided diffusion tensor imaging and tractography study.

    abstract::Diffusion tensor imaging (DTI) is a powerful MRI technique that can be used to estimate both the microstructural integrity and the trajectories of white matter pathways throughout the central nervous system. This fiber tracking (aka, "tractography") approach is often carried out using anatomically-defined seed points ...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2015.00585

    authors: Figley TD,Bhullar N,Courtney SM,Figley CR

    更新日期:2015-11-03 00:00:00

  • A predictive nature for tactile awareness? Insights from damaged and intact central-nervous-system functioning.

    abstract::In the present paper, we will attempt to gain hints regarding the nature of tactile awareness in humans. At first, we will review some recent literature showing that an actual tactile experience can emerge in absence of any tactile stimulus (e.g., tactile hallucinations, tactile illusions). According to the current mo...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2015.00287

    authors: Pia L,Garbarini F,Burin D,Fossataro C,Berti A

    更新日期:2015-05-19 00:00:00