The human brain-from cells to society.


:In December 2011, the European Science Foundation (ESF) brought together experts from a wide range of disciplines to discuss the issues that will influence the development of a healthier, more brain-aware European society. This perspective summarizes the main outcomes of that discussion and highlights important considerations to support improved mental health in Europe, including: The development of integrated neuropsychotherapeutic approaches to the treatment of psychiatric disorders.The development of more valid disease models for research into psychiatric disorders.An improved understanding of the relationship between biology and environment, particularly in relation to developmental plasticity and emerging pathology.More comparative studies to explore how scientific concepts relating to the human brain are received and understood in different sociocultural contexts.Research into the legal and ethical implications of recent developments in the brain sciences, including behavioral screening and manipulation, and emerging neurotechnologies. The broad geographical spread of the consulted experts across the whole of Europe, along with the wide range of disciplines they represent, gives these conclusions a strong scientific and pan-European endorsement. The next step will be to look closely into these five selected topics, in terms of research strategy, science policy, societal implications, and legal and ethical frameworks.


Front Hum Neurosci


Hoogland E,Patten I,Berghmans S




Has Abstract


2013-08-07 00:00:00








  • APOE2 Is Associated with Spatial Navigational Strategies and Increased Gray Matter in the Hippocampus.

    abstract::The Apolipoprotein E (APOE) gene has a strong association with Alzheimer's disease (AD). The ε4 allele is a well-documented genetic risk factor of AD. In contrast, the ε2 allele of the APOE gene is known to be protective against AD. Much of the focus on the APOE gene has been on the ε4 allele in both young and older a...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章


    authors: Konishi K,Bhat V,Banner H,Poirier J,Joober R,Bohbot VD

    更新日期:2016-07-13 00:00:00

  • The lesioned brain: still a small-world?

    abstract::The intra-arterial amobarbital procedure (IAP or Wada test) is used to determine language lateralization and contralateral memory functioning in patients eligible for neurosurgery because of pharmaco-resistant epilepsy. During unilateral sedation, functioning of the contralateral hemisphere is assessed by means of neu...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章


    authors: Douw L,van Dellen E,Baayen JC,Klein M,Velis DN,Alpherts WC,Heimans JJ,Reijneveld JC,Stam CJ

    更新日期:2010-11-11 00:00:00

  • Increased Awakenings From Non-rapid Eye Movement Sleep Explain Differences in Dream Recall Frequency in Healthy Individuals.

    abstract:Background:Dreaming is a universal experience, yet there is considerable inter-individual variability in dream recall frequency (DRF). One dominant model, the "arousal-retrieval" model, posits that intra-sleep wakefulness is required for dream traces to be encoded into long-term storage, essentially proposing that a be...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章


    authors: van Wyk M,Solms M,Lipinska G

    更新日期:2019-10-15 00:00:00

  • Somatotopy in the Human Somatosensory System.

    abstract::Previous functional magnetic resonance imaging (fMRI) studies have demonstrated digit somatotopy in primary somatosensory cortex (SI), and even shown that at high spatial resolution it is possible to resolve within-digit somatotopy. However, fMRI studies have failed to resolve the spatial organisation of digit represe...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章


    authors: Sanchez Panchuelo RM,Besle J,Schluppeck D,Humberstone M,Francis S

    更新日期:2018-06-12 00:00:00

  • The influence of the amplitude of low-frequency fluctuations on resting-state functional connectivity.

    abstract::Studies of brain functional connectivity have provided a better understanding of organization and integration of large-scale brain networks. Functional connectivity using resting-state functional magnetic resonance imaging (fMRI) is typically based upon the correlations of the low-frequency fluctuation of fMRI signals...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章


    authors: Di X,Kim EH,Huang CC,Tsai SJ,Lin CP,Biswal BB

    更新日期:2013-04-02 00:00:00

  • Selective theta-synchronization of choice-relevant information subserves goal-directed behavior.

    abstract::Theta activity reflects a state of rhythmic modulation of excitability at the level of single neuron membranes, within local neuronal groups and between distant nodes of a neuronal network. A wealth of evidence has shown that during theta states distant neuronal groups synchronize, forming networks of spatially confin...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章


    authors: Womelsdorf T,Vinck M,Leung LS,Everling S

    更新日期:2010-11-02 00:00:00

  • The neural basis of monitoring goal progress.

    abstract::The neural basis of progress monitoring has received relatively little attention compared to other sub-processes that are involved in goal directed behavior such as motor control and response inhibition. Studies of error-monitoring have identified the dorsal anterior cingulate cortex (dACC) as a structure that is sens...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章


    authors: Benn Y,Webb TL,Chang BP,Sun YH,Wilkinson ID,Farrow TF

    更新日期:2014-09-10 00:00:00

  • Using MEG to Understand the Progression of Light Sleep and the Emergence and Functional Roles of Spindles and K-Complexes.

    abstract::We used tomographic analysis of MEG signals to characterize regional spectral changes in the brain at sleep onset and during light sleep. We identified two key processes that may causally link to loss of consciousness during the quiet or "core" periods of NREM1. First, active inhibition in the frontal lobe leads to de...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章


    authors: Ioannides AA,Liu L,Poghosyan V,Kostopoulos GK

    更新日期:2017-06-16 00:00:00

  • Optic ataxia as a model to investigate the role of the posterior parietal cortex in visually guided action: evidence from studies of patient M.H.

    abstract::Optic ataxia is a neuropsychological disorder that affects the ability to interact with objects presented in the visual modality following either unilateral or bilateral lesions of the posterior parietal cortex (PPC). Patients with optic ataxia fail to reach accurately for objects, particularly when they are presented...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章


    authors: Cavina-Pratesi C,Connolly JD,Milner AD

    更新日期:2013-07-16 00:00:00

  • Corrigendum "fNIRS-based brain-computer interfaces: a review".

    abstract::[This corrects the article on p. 3 in vol. 9, PMID: 25674060.]. ...

    journal_title:Frontiers in human neuroscience

    pub_type: 已发布勘误


    authors: Naseer N,Hong KS

    更新日期:2015-03-26 00:00:00

  • Drift and ownership toward a distant virtual body.

    abstract::In body ownership illusions participants feel that a mannequin or virtual body (VB) is their own. Earlier results suggest that body ownership over a body seen from behind in extra personal space is possible when the surrogate body is visually stroked and tapped on its back, while spatially and temporal synchronous tac...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章


    authors: Pomés A,Slater M

    更新日期:2013-12-25 00:00:00

  • Electrophysiological correlates associated with contributions of perceptual and conceptual fluency to familiarity.

    abstract::The present research manipulated the fluency of unstudied items using masked repetition priming procedures during an explicit recognition test. Based on fluency-attribution accounts, which posit that familiarity can be driven by multiple forms of fluency, the relationship between masked priming-induced fluency and fam...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章


    authors: Wang W,Li B,Gao C,Xiao X,Guo C

    更新日期:2015-06-05 00:00:00

  • Spinal Cord Excitability and Sprint Performance Are Enhanced by Sensory Stimulation During Cycling.

    abstract::Spinal cord excitability, as assessed by modulation of Hoffmann (H-) reflexes, is reduced with fatiguing isometric contractions. Furthermore, spinal cord excitability is reduced during non-fatiguing arm and leg cycling. Presynaptic inhibition of Ia terminals is believed to contribute to this suppression of spinal cord...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章


    authors: Pearcey GEP,Noble SA,Munro B,Zehr EP

    更新日期:2017-12-18 00:00:00

  • Human Memories Can Be Linked by Temporal Proximity.

    abstract::Real-world memories involve the integration of multiple events across time, yet the mechanisms underlying this integration is unknown. Recent rodent studies show that distinct memories encoded within a few hours, but not several days, share a common neural ensemble, and a common fate whereby later fear conditioning ca...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章


    authors: Yetton BD,Cai DJ,Spoormaker VI,Silva AJ,Mednick SC

    更新日期:2019-09-13 00:00:00

  • The Saccadic Re-Centering Bias is Associated with Activity Changes in the Human Superior Colliculus.

    abstract::Being able to effectively explore our visual world is of fundamental importance, and it has been suggested that the straight-ahead gaze (primary position) might play a special role in this context. We employed fMRI in humans to investigate how neural activity might be modulated for saccades relative to this putative d...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章


    authors: Krebs RM,Schoenfeld MA,Boehler CN,Song AW,Woldorff MG

    更新日期:2010-11-01 00:00:00

  • BDNF Val66Met polymorphism influences age differences in microstructure of the Corpus Callosum.

    abstract::Brain-derived neurotrophic factor (BDNF) plays an important role in neuroplasticity and promotes axonal growth, but its secretion, regulated by a BDNF gene, declines with age. The low-activity (met) allele of common polymorphism BDNF val66met is associated with reduced production of BDNF. We examined whether age-relat...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章


    authors: Kennedy KM,Rodrigue KM,Land SJ,Raz N

    更新日期:2009-08-20 00:00:00

  • Differential Brain Activity in Regions Linked to Visuospatial Processing During Landmark-Based Navigation in Young and Healthy Older Adults.

    abstract::Older adults have difficulties in navigating unfamiliar environments and updating their wayfinding behavior when faced with blocked routes. This decline in navigational capabilities has traditionally been ascribed to memory impairments and dysexecutive function, whereas the impact of visual aging has often been overlo...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章


    authors: Ramanoël S,Durteste M,Bécu M,Habas C,Arleo A

    更新日期:2020-10-29 00:00:00

  • Brightness/darkness induction and the genesis of a contour.

    abstract::Visual contours often result from the integration or interpolation of fragmented edges. The strength of the completion increases when the edges share the same contrast polarity (CP). Here we demonstrate that the appearance in the perceptual field of this integrated unit, or contour of invariant CP, is concomitant with...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章


    authors: Roncato S

    更新日期:2014-10-20 00:00:00

  • Functional and Brain Activation Changes Following Specialized Upper-Limb Exercise in Parkinson's Disease.

    abstract::For the management of Parkinson's disease (PD), the concept of forced exercise (FE) has drawn interest. In PD subjects, the FE executed with lower limbs has been shown to lessen symptoms and to promote brain adaptive changes. Our study is aimed to investigate the effect of an upper-limb exercise, conceptually comparab...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章


    authors: Messa LV,Ginanneschi F,Momi D,Monti L,Battisti C,Cioncoloni D,Pucci B,Santarnecchi E,Rossi A

    更新日期:2019-10-15 00:00:00

  • Neural activity tied to reading predicts individual differences in extended-text comprehension.

    abstract::Reading comprehension depends on neural processes supporting the access, understanding, and storage of words over time. Examinations of the neural activity correlated with reading have contributed to our understanding of reading comprehension, especially for the comprehension of sentences and short passages. However, ...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章


    authors: Mossbridge JA,Grabowecky M,Paller KA,Suzuki S

    更新日期:2013-11-06 00:00:00

  • Hyperscanning: A Valid Method to Study Neural Inter-brain Underpinnings of Social Interaction.

    abstract::Social interactions are a crucial part of human life. Understanding the neural underpinnings of social interactions is a challenging task that the hyperscanning method has been trying to tackle over the last two decades. Here, we review the existing literature and evaluate the current state of the hyperscanning method...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章,评审


    authors: Czeszumski A,Eustergerling S,Lang A,Menrath D,Gerstenberger M,Schuberth S,Schreiber F,Rendon ZZ,König P

    更新日期:2020-02-28 00:00:00

  • Cognitive Function Impairments Linked to Alcohol and Cannabis Use During Adolescence: A Study of Gender Differences.

    abstract::Major neurocognitive changes occur during adolescence, making this phase one of the most critical developmental periods of life. Furthermore, this phase in life is also the time in which youth substance use begins. Several studies have demonstrated the differential associations of alcohol and cannabis use concerning t...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章


    authors: Noorbakhsh S,Afzali MH,Boers E,Conrod PJ

    更新日期:2020-04-07 00:00:00

  • Dissociation between Semantic Representations for Motion and Action Verbs: Evidence from Patients with Left Hemisphere Lesions.

    abstract::This multiple single case study contrasted left hemisphere stroke patients (N = 6) to healthy age-matched control participants (N = 15) on their understanding of action (e.g., holding, clenching) and motion verbs (e.g., crumbling, flowing). The tasks required participants to correctly identify the matching verb or ass...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章


    authors: Taylor LJ,Evans C,Greer J,Senior C,Coventry KR,Ietswaart M

    更新日期:2017-02-14 00:00:00

  • Applying the neuroscience of creativity to creativity training.

    abstract::This article investigates how neuroscience in general, and neuroscience of creativity in particular, can be used in teaching "applied creativity" and the usefulness of this approach to creativity training. The article is based on empirical data and our experiences from the Applied NeuroCreativity (ANC) program, taught...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章


    authors: Onarheim B,Friis-Olivarius M

    更新日期:2013-10-16 00:00:00

  • Strong Functional Connectivity among Homotopic Brain Areas Is Vital for Motor Control in Unilateral Limb Movement.

    abstract::The mechanism underlying brain region organization for motor control in humans remains poorly understood. In this functional magnetic resonance imaging (fMRI) study, right-handed volunteers were tasked to maintain unilateral foot movements on the right and left sides as consistently as possible. We aimed to identify t...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章


    authors: Wei P,Zhang Z,Lv Z,Jing B

    更新日期:2017-07-12 00:00:00

  • Automatic processing of unattended lexical information in visual oddball presentation: neurophysiological evidence.

    abstract::Previous electrophysiological studies of automatic language processing revealed early (100-200 ms) reflections of access to lexical characteristics of speech signal using the so-called mismatch negativity (MMN), a negative ERP deflection elicited by infrequent irregularities in unattended repetitive auditory stimulati...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章


    authors: Shtyrov Y,Goryainova G,Tugin S,Ossadtchi A,Shestakova A

    更新日期:2013-08-09 00:00:00

  • Designing Guiding Systems for Brain-Computer Interfaces.

    abstract::Brain-Computer Interface (BCI) community has focused the majority of its research efforts on signal processing and machine learning, mostly neglecting the human in the loop. Guiding users on how to use a BCI is crucial in order to teach them to produce stable brain patterns. In this work, we explore the instructions a...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章


    authors: Kosmyna N,Lécuyer A

    更新日期:2017-07-31 00:00:00

  • Long-latency TMS-evoked potentials during motor execution and inhibition.

    abstract::Transcranial magnetic stimulation (TMS) has often been used in conjunction with electroencephalography (EEG), which is effective for the direct demonstration of cortical reactivity and corticocortical connectivity during cognitive tasks through the spatio-temporal pattern of long-latency TMS-evoked potentials (TEPs). ...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章


    authors: Yamanaka K,Kadota H,Nozaki D

    更新日期:2013-11-12 00:00:00

  • Global Epileptic Seizure Identification With Affinity Propagation Clustering Partition Mutual Information Using Cross-Layer Fully Connected Neural Network.

    abstract::A longstanding challenge in epilepsy research and practice is the need to classify synchronization patterns hidden in multivariate electroencephalography (EEG) data that is routinely superimposed with intensive noise. It is essential to select a suitable feature extraction method to achieve high recognition performanc...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章


    authors: Wang F,Ke H

    更新日期:2018-10-02 00:00:00

  • Action video game play and transfer of navigation and spatial cognition skills in adolescents who are blind.

    abstract::For individuals who are blind, navigating independently in an unfamiliar environment represents a considerable challenge. Inspired by the rising popularity of video games, we have developed a novel approach to train navigation and spatial cognition skills in adolescents who are blind. Audio-based Environment Simulator...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章


    authors: Connors EC,Chrastil ER,Sánchez J,Merabet LB

    更新日期:2014-03-11 00:00:00