A Multi-Target Motor Imagery Training Using Bimodal EEG-fMRI Neurofeedback: A Pilot Study in Chronic Stroke Patients.

Abstract:

:Traditional rehabilitation techniques present limitations and the majority of patients show poor 1-year post-stroke recovery. Thus, Neurofeedback (NF) or Brain-Computer-Interface applications for stroke rehabilitation purposes are gaining increased attention. Indeed, NF has the potential to enhance volitional control of targeted cortical areas and thus impact on motor function recovery. However, current implementations are limited by temporal, spatial or practical constraints of the specific imaging modality used. In this pilot work and for the first time in literature, we applied bimodal EEG-fMRI NF for upper limb stroke recovery on four stroke-patients with different stroke characteristics and motor impairment severity. We also propose a novel, multi-target training approach that guides the training towards the activation of the ipsilesional primary motor cortex. In addition to fMRI and EEG outcomes, we assess the integrity of the corticospinal tract (CST) with tractography. Preliminary results suggest the feasibility of our approach and show its potential to induce an augmented activation of ipsilesional motor areas, depending on the severity of the stroke deficit. Only the two patients with a preserved CST and subcortical lesions succeeded in upregulating the ipsilesional primary motor cortex and exhibited a functional improvement of upper limb motricity. These findings highlight the importance of taking into account the variability of the stroke patients' population and enabled to identify inclusion criteria for the design of future clinical studies.

journal_name

Front Hum Neurosci

authors

Lioi G,Butet S,Fleury M,Bannier E,Lécuyer A,Bonan I,Barillot C

doi

10.3389/fnhum.2020.00037

subject

Has Abstract

pub_date

2020-02-18 00:00:00

pages

37

issn

1662-5161

journal_volume

14

pub_type

杂志文章
  • Resting-State Fluctuations of EEG Sensorimotor Rhythm Reflect BOLD Activities in the Pericentral Areas: A Simultaneous EEG-fMRI Study.

    abstract::Blockade of the scalp electroencephalographic (EEG) sensorimotor rhythm (SMR) is a well-known phenomenon following attempted or executed motor functions. Such a frequency-specific power attenuation of the SMR occurs in the alpha and beta frequency bands and is spatially registered at primary somatosensory and motor co...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2017.00356

    authors: Tsuchimoto S,Shibusawa S,Mizuguchi N,Kato K,Ebata H,Liu M,Hanakawa T,Ushiba J

    更新日期:2017-07-06 00:00:00

  • An Electromyographic Analysis of the Effects of Cognitive Fatigue on Online and Anticipatory Action Control.

    abstract::Cognitive fatigue is a problem for the safety of critical systems (e.g., aircraft) as it can lead to accidents, especially during unexpected events. In order to determine the extent to which it disrupts adaptive capabilities, we evaluated its effect on online and anticipatory control. Despite numerous studies conducte...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2020.615046

    authors: Salomone M,Burle B,Fabre L,Berberian B

    更新日期:2021-01-11 00:00:00

  • An Increase in Postural Load Facilitates an Anterior Shift of Processing Resources to Frontal Executive Function in a Postural-Suprapostural Task.

    abstract::Increase in postural-demand resources does not necessarily degrade a concurrent motor task, according to the adaptive resource-sharing hypothesis of postural-suprapostural dual-tasking. This study investigated how brain networks are organized to optimize a suprapostural motor task when the postural load increases and ...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2016.00420

    authors: Huang CY,Chang GC,Tsai YY,Hwang IS

    更新日期:2016-08-19 00:00:00

  • Real-Time Prediction of Observed Action Requires Integrity of the Dorsal Premotor Cortex: Evidence From Repetitive Transcranial Magnetic Stimulation.

    abstract::Studying brain mechanisms underlying the prediction of observed action, the dorsal premotor cortex (PMd) has been suggested a key area. The present study probed this notion using repetitive transcranial magnetic stimulation (rTMS) to test whether interference in this area would affect the accuracy in predicting the ti...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2018.00101

    authors: Brich LFM,Bächle C,Hermsdörfer J,Stadler W

    更新日期:2018-03-23 00:00:00

  • Resting Heart Rate Variability, Facets of Rumination and Trait Anxiety: Implications for the Perseverative Cognition Hypothesis.

    abstract::The perseverative cognition hypothesis (PCH) posits that perseveration, defined as the repetitive or sustained activation of cognitive representations of a real or imagined stressor, is a primary mechanism linking psychological (or stress) vulnerability with poor health and disease. Resting vagally mediated heart rate...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2017.00520

    authors: Williams DP,Feeling NR,Hill LK,Spangler DP,Koenig J,Thayer JF

    更新日期:2017-10-31 00:00:00

  • Attachment Representations and Brain Asymmetry during the Processing of Autobiographical Emotional Memories in Late Adolescence.

    abstract::Frontal and parietal asymmetries have repeatedly been shown to be related to specific functional mechanisms involved in emotion regulation. From a developmental perspective, attachment representations based on experiences with the caregiver are theorized to serve regulatory functions and influence how individuals deal...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2016.00644

    authors: Kungl MT,Leyh R,Spangler G

    更新日期:2016-12-26 00:00:00

  • Comparing the Neural Correlates of Conscious and Unconscious Conflict Control in a Masked Stroop Priming Task.

    abstract::Although previous studies have suggested that conflict control can occur in the absence of consciousness, the brain mechanisms underlying unconscious and conscious conflict control remain unclear. The current study used a rapid event-related functional magnetic resonance imaging design to collect data from 24 particip...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2016.00297

    authors: Jiang J,Bailey K,Xiang L,Zhang L,Zhang Q

    更新日期:2016-06-20 00:00:00

  • Hyperactivation of the habenula as a link between depression and sleep disturbance.

    abstract::Depression occurs frequently with sleep disturbance such as insomnia. Sleep in depression is associated with disinhibition of the rapid eye movement (REM) sleep. Despite the coincidence of the depression and sleep disturbance, neural substrate for depressive behaviors and sleep regulation remains unknown. Habenula is ...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章,评审

    doi:10.3389/fnhum.2013.00826

    authors: Aizawa H,Cui W,Tanaka K,Okamoto H

    更新日期:2013-12-10 00:00:00

  • Somatosensory evoked field in response to visuotactile stimulation in 3- to 4-year-old children.

    abstract::A child-customized magnetoencephalography system was used to investigate somatosensory evoked field (SEF) in 3- to 4-year-old children. Three stimulus conditions were used in which the children received tactile-only stimulation to their left index finger or visuotactile stimulation. In the two visuotactile conditions,...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2014.00170

    authors: Remijn GB,Kikuchi M,Shitamichi K,Ueno S,Yoshimura Y,Nagao K,Tsubokawa T,Kojima H,Higashida H,Minabe Y

    更新日期:2014-03-24 00:00:00

  • Feedback-Related Negativity and Frontal Midline Theta Reflect Dissociable Processing of Reinforcement.

    abstract::Prediction errors (PEs) encode representations of rewarding and aversive experiences and are critical to reinforcement processing. The feedback-related negativity (FRN), a component of the event-related potential (ERP) that is sensitive to valenced feedback, is believed to reflect PE signals. Reinforcement is also stu...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2019.00452

    authors: Rawls E,Miskovic V,Moody SN,Lee Y,Shirtcliff EA,Lamm C

    更新日期:2020-01-09 00:00:00

  • The Brain Is Faster than the Hand in Split-Second Intentions to Respond to an Impending Hazard: A Simulation of Neuroadaptive Automation to Speed Recovery to Perturbation in Flight Attitude.

    abstract::The goal of this research is to test the potential for neuroadaptive automation to improve response speed to a hazardous event by using a brain-computer interface (BCI) to decode perceptual-motor intention. Seven participants underwent four experimental sessions while measuring brain activity with magnetoencephalograp...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2016.00187

    authors: Callan DE,Terzibas C,Cassel DB,Sato MA,Parasuraman R

    更新日期:2016-04-27 00:00:00

  • Effector-Specific Characterization of Brain Dynamics in Manual vs. Oculomotor Go/NoGo Tasks.

    abstract::Motor inhibitory control (IC), the ability to suppress unwanted actions, has been previously shown to rely on domain-general IC processes that are involved in a wide range of IC tasks. Nevertheless, the existence of effector-specific regions and activation patterns that would differentiate manual vs. oculomotor respon...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2020.600667

    authors: Simonet M,Ruggeri P,Barral J

    更新日期:2020-12-03 00:00:00

  • Examining the role of the temporo-parietal network in memory, imagery, and viewpoint transformations.

    abstract::The traditional view of the medial temporal lobe (MTL) focuses on its role in episodic memory. However, some of the underlying functions of the MTL can be ascertained from its wider role in supporting spatial cognition in concert with parietal and prefrontal regions. The MTL is strongly implicated in the formation of ...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2014.00709

    authors: Dhindsa K,Drobinin V,King J,Hall GB,Burgess N,Becker S

    更新日期:2014-09-16 00:00:00

  • Change in Brainstem Gray Matter Concentration Following a Mindfulness-Based Intervention is Correlated with Improvement in Psychological Well-Being.

    abstract::Individuals can improve their levels of psychological well-being (PWB) through utilization of psychological interventions, including the practice of mindfulness meditation, which is defined as the non-judgmental awareness of experiences in the present moment. We recently reported that an 8-week-mindfulness-based stres...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2014.00033

    authors: Singleton O,Hölzel BK,Vangel M,Brach N,Carmody J,Lazar SW

    更新日期:2014-02-18 00:00:00

  • Magnitude Processing in the Brain: An fMRI Study of Time, Space, and Numerosity as a Shared Cortical System.

    abstract::Continuous dimensions, such as time, space, and numerosity, have been suggested to be subserved by common neurocognitive mechanisms. Neuroimaging studies that have investigated either one or two dimensions simultaneously have consistently identified neural correlates in the parietal cortex of the brain. However, studi...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2016.00500

    authors: Skagerlund K,Karlsson T,Träff U

    更新日期:2016-10-05 00:00:00

  • Association of hair iron levels with creativity and psychological variables related to creativity.

    abstract::Creativity generally involves the conception of original and valuable ideas. Previous studies have suggested an association between creativity and the dopaminergic system, and that physical activity facilitates creativity. Iron plays a key role in the dopaminergic system and physical activity. Here, we newly investiga...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2013.00875

    authors: Takeuchi H,Taki Y,Sekiguchi A,Nouchi R,Kotozaki Y,Nakagawa S,Miyauchi CM,Iizuka K,Yokoyama R,Shinada T,Yamamoto Y,Hanawa S,Araki T,Hashizume H,Kunitoki K,Sassa Y,Kawashima R

    更新日期:2013-12-18 00:00:00

  • Digital Biomarkers for the Early Detection of Mild Cognitive Impairment: Artificial Intelligence Meets Virtual Reality.

    abstract::Elderly people affected by Mild Cognitive Impairment (MCI) usually report a perceived decline in cognitive functions that deeply impacts their quality of life. This subtle waning, although it cannot be diagnosable as dementia, is noted by caregivers on the basis of their relative's behaviors. Crucially, if this condit...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2020.00245

    authors: Cavedoni S,Chirico A,Pedroli E,Cipresso P,Riva G

    更新日期:2020-07-24 00:00:00

  • Effective Connectivity within the Default Mode Network: Dynamic Causal Modeling of Resting-State fMRI Data.

    abstract::The Default Mode Network (DMN) is a brain system that mediates internal modes of cognitive activity, showing higher neural activation when one is at rest. Nowadays, there is a lot of interest in assessing functional interactions between its key regions, but in the majority of studies only association of Blood-oxygen-l...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2016.00014

    authors: Sharaev MG,Zavyalova VV,Ushakov VL,Kartashov SI,Velichkovsky BM

    更新日期:2016-02-01 00:00:00

  • Neuromagnetic vistas into typical and atypical development of frontal lobe functions.

    abstract::The frontal lobes are involved in many higher-order cognitive functions such as social cognition executive functions and language and speech. These functions are complex and follow a prolonged developmental course from childhood through to early adulthood. Magnetoencephalography (MEG) is ideal for the study of develop...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章,评审

    doi:10.3389/fnhum.2014.00453

    authors: Taylor MJ,Doesburg SM,Pang EW

    更新日期:2014-06-18 00:00:00

  • Repeating with the right hemisphere: reduced interactions between phonological and lexical-semantic systems in crossed aphasia?

    abstract::Knowledge on the patterns of repetition amongst individuals who develop language deficits in association with right hemisphere lesions (crossed aphasia) is very limited. Available data indicate that repetition in some crossed aphasics experiencing phonological processing deficits is not heavily influenced by lexical-s...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2013.00675

    authors: De-Torres I,Dávila G,Berthier ML,Walsh SF,Moreno-Torres I,Ruiz-Cruces R

    更新日期:2013-10-18 00:00:00

  • Cortical Neural Synchronization Underlies Primary Visual Consciousness of Qualia: Evidence from Event-Related Potentials.

    abstract::This article reviews three experiments on event-related potentials (ERPs) testing the hypothesis that primary visual consciousness (stimulus self-report) is related to enhanced cortical neural synchronization as a function of stimulus features. ERP peak latency and sources were compared between "seen" trials and "not ...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章,评审

    doi:10.3389/fnhum.2016.00310

    authors: Babiloni C,Marzano N,Soricelli A,Cordone S,Millán-Calenti JC,Del Percio C,Buján A

    更新日期:2016-06-30 00:00:00

  • Neurophysiological correlates of anhedonia in feedback processing.

    abstract::Disturbances in feedback processing and a dysregulation of the neural circuit in which the cingulate cortex plays a key role have been frequently observed in depression. Since depression is a heterogeneous disease, instead of focusing on the depressive state in general, this study investigated the relations between th...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2013.00096

    authors: Mies GW,Van den Berg I,Franken IH,Smits M,Van der Molen MW,Van der Veen FM

    更新日期:2013-03-26 00:00:00

  • Subthreshold Electrical Noise Applied to the Plantar Foot Enhances Lower-Limb Cutaneous Reflex Generation.

    abstract::Reflex responses generated by cutaneous mechanoreceptors of the plantar foot are important for the maintenance of balance during postural tasks and gait. With aging, reflex generation, particularly from fast adapting type I receptors, is reduced, which likely contributes to impaired postural stability in this populati...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2020.00351

    authors: Sharma T,Peters RM,Bent LR

    更新日期:2020-08-26 00:00:00

  • A FreeSurfer-compliant consistent manual segmentation of infant brains spanning the 0-2 year age range.

    abstract::We present a detailed description of a set of FreeSurfer compatible segmentation guidelines tailored to infant MRI scans, and a unique data set of manually segmented acquisitions, with subjects nearly evenly distributed between 0 and 2 years of age. We believe that these segmentation guidelines and this dataset will h...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2015.00021

    authors: de Macedo Rodrigues K,Ben-Avi E,Sliva DD,Choe MS,Drottar M,Wang R,Fischl B,Grant PE,Zöllei L

    更新日期:2015-02-18 00:00:00

  • Sex Differences in Categorical Adaptation for Faces and Chinese Characters during Early Perceptual Processing.

    abstract::Previous event-related potential studies support sex differences in the N170 response during face and word processing; however, it remains unclear whether N170 categorical adaptation for faces and words is different between women and men. Using an adaptation paradigm, in which an adaptor and subsequent test stimulus a...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2017.00656

    authors: Zhu C,Ma X,Ji L,Chen S,Cao X

    更新日期:2018-01-12 00:00:00

  • Balance Impairments after Brachial Plexus Injury as Assessed through Clinical and Posturographic Evaluation.

    abstract:OBJECTIVE:To investigate whether a sensorimotor deficit of the upper limb following a brachial plexus injury (BPI) affects the upright balance. DESIGN:Eleven patients with a unilateral BPI and 11 healthy subjects were recruited. The balance assessment included the Berg Balance Scale (BBS), the number of feet touches o...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2015.00715

    authors: Souza L,Lemos T,Silva DC,de Oliveira JM,Guedes Corrêa JF,Tavares PL,Oliveira LA,Rodrigues EC,Vargas CD

    更新日期:2016-01-25 00:00:00

  • Focal dystonia in musicians: linking motor symptoms to somatosensory dysfunction.

    abstract::Musician's dystonia (MD) is a neurological motor disorder characterized by involuntary contractions of those muscles involved in the play of a musical instrument. It is task-specific and initially only impairs the voluntary control of highly practiced musical motor skills. MD can lead to a severe decrement in a musici...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2013.00297

    authors: Konczak J,Abbruzzese G

    更新日期:2013-06-25 00:00:00

  • Illuminating the dark matter of social neuroscience: Considering the problem of social interaction from philosophical, psychological, and neuroscientific perspectives.

    abstract::Successful human social interaction depends on our capacity to understand other people's mental states and to anticipate how they will react to our actions. Despite its importance to the human condition, the exact mechanisms underlying our ability to understand another's actions, feelings, and thoughts are still a mat...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2012.00190

    authors: Przyrembel M,Smallwood J,Pauen M,Singer T

    更新日期:2012-06-21 00:00:00

  • Evaluating the relationship between change in performance on training tasks and on untrained outcomes.

    abstract::Training interventions for older adults are designed to remediate performance on trained tasks and to generalize, or transfer, to untrained tasks. Evidence for transfer is typically based on the trained group showing greater improvement than controls on untrained tasks, or on a correlation between gains in training an...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2014.00617

    authors: Zelinski EM,Peters KD,Hindin S,Petway KT 2nd,Kennison RF

    更新日期:2014-08-13 00:00:00

  • Assessment of hemispheric dominance for receptive language in pediatric patients under sedation using magnetoencephalography.

    abstract::Non-invasive assessment of hemispheric dominance for receptive language using magnetoencephalography (MEG) is now a well-established procedure used across several epilepsy centers in the context of pre-surgical evaluation of children and adults while awake, alert and attentive. However, the utility of MEG for the same...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2014.00657

    authors: Rezaie R,Narayana S,Schiller K,Birg L,Wheless JW,Boop FA,Papanicolaou AC

    更新日期:2014-08-21 00:00:00