Evaluation of Serum Des-Gamma-Carboxy Prothrombin for the Diagnosis of Hepatitis B Virus-Related Hepatocellular Carcinoma: A Meta-Analysis.

abstract：Background:Obstructive sleep apnea (OSA) was highly prevalent in patients with type 2 diabetes (T2D). Cathepsin S (CTSS), a cysteine protease, is involved in the inflammatory activity in T2D and hypoxia conditions. The aim of the study was to evaluate whether CTSS could be involved in the inflammatory reaction of OSA i...

journal_title：Disease markers

authors： Wen W,Sun H,Yang Y,Jia Y,Fang F,Qin Y,Zhang M,Wei Y

更新日期：2020-09-25 00:00:00

abstract：:We first investigated the difference in microRNA expression between normal NP cells and degenerative NP cells using gene chip. We have found that the expression of ERK1/2 was decreased with overexpression of miR-155 in normal nucleus pulposus cell. Expression of ERK1/2 was increased with inhibition of miR-155. Overexp...

journal_title：Disease markers

authors： Ye D,Dai L,Yao Y,Qin S,Xie H,Wang W,Liang W

更新日期：2016-01-01 00:00:00

abstract：:Nevirapine (NVP) is an effective nonnucleoside reverse transcriptase inhibitor (NNRTI) of particular interest as it is often used in resource limited countries. However, one of the main concerns with the use of NVP is hepatotoxicity and elevation of liver enzymes as a consequence of highly active antiretroviral therap...

journal_title：Disease markers

authors： Wongtrakul J,Thongtan T,Roytrakul S,Kumrapich B,Janphen K,Praparattanapan J,Supparatpinyo K,Smith DR

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:Particularly interesting new cysteine-histidine rich protein (PINCH) is an important component of the local adhesion complexes and upregulated in several types of malignancies, and involved in the incidence and development of tumours. PINCH expression is also independently correlated with poorer survival in p...

journal_title：Disease markers

authors： Zhu ZL,Yan BY,Zhang Y,Yang YH,Wang ZM,Zhang HZ,Wang MW,Zhang XH,Sun XF

更新日期：2012-01-01 00:00:00

abstract：INTRODUCTION:Amongst the genitourinary cancers, carcinoma of the urinary bladder is one of the leading causes of death in India. Hypermethylation of the CpG islands of gene promoter is one of the earliest and most frequent epigenetic alterations leading to cancer as well as in its development. Several studies have sugg...

journal_title：Disease markers

authors： Ali Hosseini S,Sobti RC,Malekzadeh K,Singh SK,Joshi K

更新日期：2010-01-01 00:00:00

abstract：:The human papilloma virus (HPV) associated with hyperplastic epithelium in an oral denture fibroma was examined by southern blot hybridization. Extracted DNA was hybridized with full length linear HPV type 2a, 6b, 11, 16, 18, 31 and 33 DNAs as a mixed probe only under low stringent conditions. The hybridized bands dig...

journal_title：Disease markers

authors： Yamaguchi T,Shindoh M,Amemiya A,Notani K,Fukuda H,Sakaoka H,Inoue M,Fujinaga K

更新日期：1997-04-01 00:00:00

abstract：Backgrounds:Both pretreatment serum CRP (C-reactive protein) level and ALB (albumin) level have been found to be predictive of survival for multiple malignancies including sarcoma. Since both of the GPS (Glasgow prognostic score) and CAR (C-reactive protein to albumin ratio) are based on the combination of CRP and ALB,...

journal_title：Disease markers

authors： Fang E,Wang X,Feng J,Zhao X

更新日期：2020-01-07 00:00:00

abstract：:Two-dimensional gel analysis (NEPHGE) of the molecules precipitated by the HLA-DR monomorphic antibody L243 showed a single and identical alpha chain spot from two consanguineous cell lines, BM14 and MCF. The latter was derived from a rheumatoid arthritis patient. No apparent structural polymorphism of the HLA-DR beta...

journal_title：Disease markers

authors： Fernandez N,Labeta M,Kurpisz M,Solana R,Festenstein H

更新日期：1986-06-01 00:00:00

abstract：:Respiratory syncytial virus (RSV) is the most common viral respiratory pathogen during infancy world wide. It induces innate and adaptive immune response in host cells. The toll like receptor 4 (TLR4)/CD14 complex is particularly important for the initiation of an innate immune response to RSV. Thus we were interested...

journal_title：Disease markers

authors： Puthothu B,Forster J,Heinzmann A,Krueger M

更新日期：2006-01-01 00:00:00

abstract：:RFLP HLA-DRB1 analysis was performed on a total of 83 children born from HIV-infected mothers, 35 of whom were shown to be HIV-infected, while 48 reverted from seropositivity to seronegativity, indicating that they were not infected. Moreover, 89 healthy children were used as controls. It has been found that DRB1-14a ...

journal_title：Disease markers

authors： Greggio NA,Cameran M,Giaquinto C,Zacchello F,Koroliuk D,Colizzi V

更新日期：1993-06-01 00:00:00

abstract：BACKGROUND:Autism is among the commonest neurodevelopmental childhood disorders worldwide; its aetiology is still unknown. Iron metabolism alteration in the central nervous system is recently implicated as a risk factor for several neurodegenerative disorders. Haemochromatosis HFE gene polymorphisms (p.H63D and p.C282Y...

journal_title：Disease markers

authors： Gebril OH,Meguid NA

更新日期：2011-01-01 00:00:00

abstract：:Purpose. The aim of this study was to evaluate the sensitivity of pleural C-reactive protein (CRP) biomarker levels in identifying parapneumonic effusions. Methods. A single-center, retrospective review of 244 patients diagnosed with pleural effusions was initiated among patients at the Rabin Medical Center, Petah Tik...

journal_title：Disease markers

authors： Izhakian S,Wasser WG,Fox BD,Vainshelboim B,Kramer MR

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Liver cirrhosis (LC) is the final stage of most of chronic liver diseases and is almost caused by chronic hepatitis B (CHB) in China. Liver biopsy is the reference method for the evaluation of liver cirrhosis. However, it is an invasive procedure with inherent risk. The aim of this study was to construct a n...

journal_title：Disease markers

authors： Cao Y,Hu ZD,Liu XF,Deng AM,Hu CJ

更新日期：2013-01-01 00:00:00

abstract：Background:The role of miR-200c in gastric cancer remains controversial. This study is aimed at clarifying the diagnostic and prognostic value of miR-200c in gastric cancer through a meta-analysis. Methods:A comprehensive literature search of PubMed, Embase, and Ovid library databases was conducted. The studies includ...

journal_title：Disease markers

authors： Huang ZS,Guo XW,Zhang G,Liang LX,Nong B

更新日期：2019-04-04 00:00:00

abstract：Background:Determination of neonate serum's N-acetyl-β-hexosaminidase (HEX) activity and correlation results with Apgar scale and factors routinely determined in newborn serum. Aims:Providing reference values of neonates serum HEX activities, and indicate their diagnostic significance. Study design:The study was perf...

journal_title：Disease markers

authors： Chojnowska S,Kamianowska M,Baran P,Zwierz K,Szczepański M

更新日期：2018-07-02 00:00:00

abstract：:Decreased levels of brain-derived neurotrophic factor (BDNF) are assumed to play a crucial role in the pathophysiology of mild neurocognitive disorders (MNCDs). In this study, we compared plasma BDNF levels (at baseline and after two months of treatment with escitalopram) in patients with the main types of MNCDs and n...

journal_title：Disease markers

authors： Levada OA,Cherednichenko NV,Trailin AV,Troyan AS

更新日期：2016-01-01 00:00:00

abstract：Background:Obese women with gestational diabetes mellitus (GDM) have a higher risk of adverse outcomes than women with obesity or GDM alone. Our study is aimed at investigating the discriminatory power of circulatory Wnt1-inducible signaling pathway protein-1 (WISP1), a novel adipocytokine, on the copresence of prepreg...

journal_title：Disease markers

authors： Liu L,Hu J,Yang L,Wang N,Liu Y,Wei X,Gao M,Wang Y,Ma Y,Wen D

更新日期：2020-04-14 00:00:00

abstract：:Biomarker measurements now support key decisions throughout the drug development process, from lead optimization to regulatory approvals. They are essential for documenting exposure-response relationships, specificity and potency toward the molecular target, untoward effects, and therapeutic applications. In a broader...

journal_title：Disease markers

authors： Swanson BN

更新日期：2002-01-01 00:00:00

abstract：:We aim to identify the mutations of deafness genes using massively parallel DNA sequencing in the 12 Uyghur families. SNPscan method was used to screen against the 124 sites in the common deafness genes in probands. Subjects with SNPscan negativity were subject to massively parallel DNA sequencing for the sequencing o...

journal_title：Disease markers

authors： Chen Y,Lu Y,Kuyaxi P,Cheng J,Zhao J,Zhao Q,Musha P,Zhang H,Yuan H

更新日期：2018-03-05 00:00:00

abstract：:Nasopharyngeal carcinoma (NPC) is a head and neck cancer that is highly found in distinct geographic areas, such as Southeast Asia. The management of NPC remains burdensome as the prognosis is poor due to the late presentation of the disease and the complex nature of NPC pathogenesis. Therefore, it is necessary to fin...

journal_title：Disease markers

authors： Janvilisri T

更新日期：2015-01-01 00:00:00

abstract：:Epithelial cancers, including those of the skin and cervix, are the most common type of cancers in humans. Many recent studies have attempted to use Raman spectroscopy to diagnose these cancers. In this paper, Raman spectral markers related to the temporal and spatial effects of cervical and skin cancers are examined ...

journal_title：Disease markers

authors： Keller MD,Kanter EM,Lieber CA,Majumder SK,Hutchings J,Ellis DL,Beaven RB,Stone N,Mahadevan-Jansen A

更新日期：2008-01-01 00:00:00

abstract：:Chromosomal aneuploidy consists the leading cause of fetal death in our species. Around 50% of spontaneous abortions until 15 weeks of gestational age are chromosomally aneuploid, with trisomies accounting for 50% of the abnormal abortions. Trisomy 21 is the most common chromosome abnormality in liveborns and is usual...

journal_title：Disease markers

authors： Kokotas H,Grigoriadou M,Mikkelsen M,Giannoulia-Karantana A,Petersen MB

更新日期：2009-01-01 00:00:00

abstract：:Basal cell carcinoma (BCC) is the world's leading skin cancer in terms of frequency at the moment and its incidence continues to rise each year, leading to profound negative psychosocial and economic consequences. UV exposure is the most important environmental factor in the development of BCC in genetically predispos...

journal_title：Disease markers

authors： Lupu M,Caruntu C,Ghita MA,Voiculescu V,Voiculescu S,Rosca AE,Caruntu A,Moraru L,Popa IM,Calenic B,Greabu M,Costea DE

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:The apolipoprotein (apo) B/apoA-I ratio represents the balance between apoB-rich atherogenic particles and apoA-I-rich antiatherogenic particles, and this ratio is considered to be a marker of cardiovascular risk. Although many studies have demonstrated the importance of the apoB/apoA-I ratio in predicting t...

journal_title：Disease markers

authors： Kaneva AM,Potolitsyna NN,Bojko ER,Odland JØ

更新日期：2015-01-01 00:00:00

abstract：:Tumor-induced osteomalacia (TIO) is a rare acquired paraneoplastic disorder and fibroblast growth factor 23 (FGF23) plays a key role in its pathogenesis. This study was conducted to describe a novel FGF23 detecting procedure and describe clinical features of the disease. Fourteen TIO cases were retrieved and FGF23 exp...

journal_title：Disease markers

authors： Hu F,Jiang C,Zhang Q,Shi H,Wei L,Wang Y

更新日期：2016-01-01 00:00:00

abstract：Background:Cardiovascular disease (CVD) risks persist in patients despite the use of conventional treatments. This might be due to chronic inflammation as reflected in epidemiological studies associating circulating low-grade inflammatory markers with CVD recurrent events. Here, we explored this potential link by asses...

journal_title：Disease markers

authors： Khadir A,Kavalakatt S,Dehbi M,Alarouj M,Bennakhi A,Tiss A,Elkum N

更新日期：2018-12-13 00:00:00

abstract：BACKGROUND:We aimed to determine whether serum soluble CD30 (sCD30) could identify recipients at high risk for unfavorable early and late kidney transplant outcomes. METHODS:Serum sCD30 was measured on the day of kidney transplantation and on the 4th day posttransplant. We assessed the value of these measurements in p...

journal_title：Disease markers

authors： Trailin AV,Ostapenko TI,Nykonenko TN,Nesterenko SN,Nykonenko OS

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVES:Increases in red blood cell distribution width (RDW) and NT-proBNP (N-terminal pro-B-type natriuretic peptide) predict the mortality of chronic heart failure patients undergoing cardiac resynchronization therapy (CRT). It was hypothesized that RDW is independent of and possibly even superior to NT-proBNP fro...

journal_title：Disease markers

authors： Boros AM,Perge P,Jenei Z,Karády J,Zima E,Molnár L,Becker D,Gellér L,Prohászka Z,Merkely B,Széplaki G

更新日期：2016-01-01 00:00:00

abstract：Objective:Long noncoding RNAs (lncRNAs) have been strongly associated with various types of cancer. The present study aimed at exploring the diagnostic and prognostic value of lncRNA Zinc finger protein 667-antisense RNA 1 (ZNF667-AS1) in glioma patients. Patients and Methods. The expressions of ZNF667-AS1 were detecte...

journal_title：Disease markers

authors： Yuan Q,Gao C,Lai XD,Chen LY,Lai TB

更新日期：2020-11-16 00:00:00

abstract：BACKGROUND:Previous studies on the role of inflammation in the pathophysiology of sickle cell disease (SCD) suggested that the CCR5Δ32 allele, which is responsible for the production of truncated C-C chemokine receptor type 5 (CCR5), could confer a selective advantage on patients with SCD because it leads to a less eff...

journal_title：Disease markers

authors： Lopes MP,Santos MN,Faber EW,Bezerra MA,Hatzlhofer BL,Albuquerque DM,Zaccariotto TR,Ribeiro DM,Araújo Ada S,Costa FF,Sonati Mde F

更新日期：2014-01-01 00:00:00