Abstract:
:Dr. Masur and colleagues(1) from the Childhood Absence Epilepsy Study Group tried to answer a few important questions regarding childhood absence epilepsy (CAE) in their article "Pretreatment cognitive deficits and treatment effects on attention in childhood absence epilepsy." First, they wanted to know whether children with absence epilepsy have any problems with thinking before starting medications. If the children have problems with thinking, the authors wanted to identify the specific types of thinking problems the children have. The authors also wanted to assess what effect seizure medications have on attention in these children. In principle, medications could improve or worsen attention. The possible effects of medication on attention may or may not depend on whether the medications control the seizures.
journal_name
Neurologyjournal_title
Neurologyauthors
Thio LLdoi
10.1212/01.wnl.0000436060.67147.25subject
Has Abstractpub_date
2013-10-29 00:00:00pages
e138-9issue
18eissn
0028-3878issn
1526-632Xpii
81/18/e138journal_volume
81pub_type
杂志文章相关文献
NEUROLOGY文献大全abstract::We report of a woman aged 52 years born to consanguineous parents and seeking treatment for progressive dementia and delusion. Neurologic examination revealed dementia and emotional instability, indifference, and confabulation. There was also mild spasticity of the bilateral lower limbs. MRI revealed diffuse white mat...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000123117.11264.0e
更新日期:2004-05-11 00:00:00
abstract:OBJECTIVE:We investigated if tau, microtubular binding protein, in serum and ventricular CSF (vCSF) in patients with severe traumatic brain injury (TBI) during the initial posttraumatic days correlated to 1-year outcome.
METHODS:Patients with severe TBI (n = 39, Glasgow Coma Scale score journal_title:Neurology pub_type: 杂志文章 doi:10.1212/01.wnl.0000242732.06714.0f 更新日期:2006-11-14 00:00:00
abstract:OBJECTIVE:To determine the frequency of Lewy bodies (LB) in progressive supranuclear palsy (PSP). BACKGROUND:LB are characteristic of PD, but are also found in normal controls and in other neurodegenerative diseases, especially AD. METHOD:The authors evaluated the brains of 72 consecutive cases of pathologically conf...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.57.9.1675
更新日期:2001-11-13 00:00:00
abstract:OBJECTIVE:This study correlated the extent of abnormalities detected by different magnetic resonance imaging (MRI) techniques [proton density (PD)-weighted, T1-weighted, and magnetization transfer imaging (MTI)] with the overall cognitive, frontal lobe, and memory impairments in patients with MS. PATIENTS:There were 3...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.50.6.1601
更新日期:1998-06-01 00:00:00
abstract:OBJECTIVE:Unilateral temporoparietal injury may result in an attentional deficit for stimuli presented in contralesional space. Thus, bilateral temporoparietal degeneration associated with Alzheimer disease (AD) might result in a bilateral attentional disturbance. Tests for hemispatial neglect, however, primarily asses...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000276956.65528.d4
更新日期:2007-09-11 00:00:00
abstract::Patients with myotonic dystrophy often develop respiratory failure caused by alveolar hypoventilation. Abnormalities in the ventilatory response to hypoxia and hypercapnia may explain this phenomenon. Accordingly, hypoxic and hypercapnic responses were measured in seven patients with myotonic dystrophy who had only mi...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.27.12.1125
更新日期:1977-12-01 00:00:00
abstract::Ten patients with refractory temporal lobe epilepsy performed a word-position association learning task every 24 hours during video EEG monitoring. On 55 occasions recall performance was tested 30 minutes and 24 hours after the initial learning phase. Patients with left- but not right-sided temporal lobe epilepsy exhi...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.57.1.125
更新日期:2001-07-10 00:00:00
abstract::Systematic screening of many compounds in animal models led to identification of the established antiepileptic drugs (AEDs). By contrast, the newer AEDs were specifically designed to enhance an inhibitory process or to inhibit a specific excitatory pathway. However, it was later discovered that some of the designed dr...
journal_title:Neurology
pub_type: 杂志文章,评审
doi:
更新日期:2000-01-01 00:00:00
abstract::The childhood type fo dermatomyositis, which occurs in children and young adults, shows a specific constellation of pathologic changes in muscle. Capillary necrosis leads to capillary loss, generally starting on the periphery of muscle fascicles. Electron microscopy discloses undulating tubules in endothelial cells, l...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.26.10.952
更新日期:1976-10-01 00:00:00
abstract:OBJECTIVE:To characterize disease severity and distribution of disability in pediatric-onset multiple sclerosis (POMS) and to develop an optimized modeling scale for measuring disability, we performed a multicenter retrospective analysis of disability scores in 873 persons with POMS over time and compared this to previ...
journal_title:Neurology
pub_type: 杂志文章,多中心研究
doi:10.1212/WNL.0000000000010414
更新日期:2020-09-29 00:00:00
abstract::One hundred and eight patients with independent, multifocal, spike discharges in the EEG were studied. The abnormality occurred at all ages but was more frequent between 4 and 7 years. The basic EEG activity in wake tracing was invariably slow for the age of the patient. The majority of the patients with independent m...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.26.7.667
更新日期:1976-07-01 00:00:00
abstract::A 41-year-old man presented with bilateral posterior cerebral artery infarcts. He had visual object agnosia and prosopagnosia with preservation of reading abilities. There was also defective visual memory, topographic orientation, and color perception, as well as simultanagnosia. From the clinical facts and CT finding...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.34.7.947
更新日期:1984-07-01 00:00:00
abstract::We have discovered a new Italian pedigree with autosomal-dominant ALS. The pedigree, at present, comprises 75 members distributed in five generations. ALS was diagnosed in eight patients. The mean +/- SD age of onset of the disease was 46.8 +/- 13.5 years, with a range of 29 to 63 years. The mean +/- SD duration of th...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.44.2.347
更新日期:1994-02-01 00:00:00
abstract::The authors conducted a randomized, double-blind, placebo-controlled, twofold crossover study in 16 patients with MS who presented with severe spasticity to investigate safety, tolerability, and efficacy of oral Delta(9)-Tetrahydrocannabinol (THC) and Cannabis sativa plant extract. Both drugs were safe, but adverse ev...
journal_title:Neurology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1212/wnl.58.9.1404
更新日期:2002-05-14 00:00:00
abstract:BACKGROUND:In patients with trigeminal neuralgia, results of clinical examination of sensory function are normal. Reflex and evoked potential studies have already provided information on large-afferent (non-nociceptive) function. Using laser-evoked potentials (LEP), the authors sought information on small-afferent (noc...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.56.12.1722
更新日期:2001-06-26 00:00:00
abstract::The apolipoprotein E gene has been associated with various types of dementia. We studied the connection between the APOE gene and the risk and onset of disease in 34 patients with clinically diagnosed frontal lobe dementia (FLD) derived from a population-based study in the Netherlands. A significant increased risk of ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.48.6.1526
更新日期:1997-06-01 00:00:00
abstract:OBJECTIVE:To determine whether whole-brain, event-related fMRI can distinguish healthy older adults with known Alzheimer disease (AD) risk factors (family history, APOE epsilon4) from controls using a semantic memory task involving discrimination of famous from unfamiliar names. METHODS:Sixty-nine cognitively asymptom...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0b013e3181b389ad
更新日期:2009-08-25 00:00:00
abstract::The authors describe a case of syphilitic amyotrophy in a 37-year-old man presenting with subacute progressive painless weakness in the right arm. Syphilitic amyotrophy is still an existing differential diagnosis of painless and progressive weakness. The authors explore potential obstacles in the diagnostic workup and...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000046584.72672.d3
更新日期:2003-02-11 00:00:00
abstract::A patient received an overdose of intravascular contrast medium and experienced protracted seizures associated with radiographic evidence of prolonged retention of the contrast agent in the cerebral cortex, basal ganglia, and thalami. This is only the second report and the first survivor of a similar neurologic syndro...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.43.4.836
更新日期:1993-04-01 00:00:00
abstract::We present a new benign eating disorder associated with lesions involving parts of the right anterior cerebral hemisphere. This "gourmand" syndrome describes a preoccupation with food and a preference for fine eating. Two exemplary case reports illustrate this new syndrome. Analysis of the clinical and anatomical data...
journal_title:Neurology
pub_type: 杂志文章,评审
doi:10.1212/wnl.48.5.1185
更新日期:1997-05-01 00:00:00
abstract::A 33-year-old man with complex partial seizures developed de novo hypertension after the initiation of carbamazepine, which resolved on discontinuation. Although rare, a variety of cardiovascular effects including hypertension have been reported with carbamazepine. Numerous mechanisms may be responsible; however, shar...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.59.2.275
更新日期:2002-07-23 00:00:00
abstract::Forty-seven consecutive patients presenting acutely with repetitive symptoms indicative of anterior circulation ischemia ("crescendo" transient ischemic attacks) were evaluated to identify clinical features that might reliably predict the presence of significant stenosis, ulceration, or both in the presumably symptoma...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.38.2.198
更新日期:1988-02-01 00:00:00
abstract::We studied a 55-year-old woman with macrosquare wave jerks and macrosaccadic oscillations with a vertical component. The oscillations almost completely disappeared after administration of diazepam, clonazepam, thiamylal, or phenobarbital. A disorder of GABAergic tonic inhibitory system from the substantia nigra to sup...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.36.9.1230
更新日期:1986-09-01 00:00:00
abstract::The authors correlated neurologic features of rostral lateral pontine infarct (rLPI) with lesion location on MRI. rLPI is a motor-sensory stroke presenting as crural monoparesis or crural dominant hemiparesis and segmental superficial or deep sensory disturbances. The dorsolateral pontine base causes crural paresis wi...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000072323.19180.b7
更新日期:2003-07-08 00:00:00
abstract:OBJECTIVE:To use punch skin biopsies to evaluate the loss of intra-epidermal nerve fibers in sensory neuropathies. BACKGROUND:Previous assessments of epidermal nerve fibers have been constrained by relatively insensitive staining techniques and variability in quantification. METHODS:Punch skin biopsies were performed...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.45.10.1848
更新日期:1995-10-01 00:00:00
abstract:OBJECTIVES:To investigate the relationship between markers of vitamin B(12) status and brain volume loss per year over a 5-year period in an elderly population. METHODS:A prospective study of 107 community-dwelling volunteers aged 61 to 87 years without cognitive impairment at enrollment. Volunteers were assessed year...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000325581.26991.f2
更新日期:2008-09-09 00:00:00
abstract::Clinical presentation of carotid artery dissection (CAD) is variable, including acute or subacute headache, cervical pain, or focal neurologic deficit that occurs spontaneously, after a high-speed neck manipulation, or trauma. Isolated lower cranial nerve palsy in carotid dissection is uncommon. ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0b013e31828727e8
更新日期:2013-03-12 00:00:00
abstract::Serum levels of creatine phosphokinase (CPK) and pyruvic kinase (PK) were determined in 42 controls, 57 patients with various neuromuscular disorders, and 23 female relatives of Duchenne dystrophy patients. CPK and PK enzyme activities were increased in comparable numbers of muscle disease patients and female carriers...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.28.10.1047
更新日期:1978-10-01 00:00:00
abstract::We studied reciprocal inhibition by recording the changes in firing probability of single motor units of the tibialis anterior muscle following stimulation of low-threshold afferents in the posterior tibial nerve. In 15 patients with cerebral palsy, the inhibition was as great or greater than normal. We found no evide...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.40.4.653
更新日期:1990-04-01 00:00:00
abstract::Because Hughlings Jackson directed that his personal documents be destroyed upon his death, none of his own clinical records are known. However, we have discovered several pages of notes in the Royal London Hospital Archive written in 1893 by Jackson to his House Physician at Queen Square concerning his proposals for ...
journal_title:Neurology
pub_type: 传,历史文章,杂志文章
doi:10.1212/01.wnl.0000230142.89488.a0
更新日期:2006-08-22 00:00:00