Abstract:
:A multichannel continuous-flow apparatus for dissolution rate measurements is described. Typical data are presented to demonstrate its utility for studies with bulk drug powders as well as with tablets and capsules without any change of setup. Procedures are given for the preparation of powder samples for dissolution studies and for a simple method of changing pH for "retard" tablets. The precision in dissolution rates obtained with this apparatus and method is 1-10% mean RSD. The advantages of the method are flexibility, reproducibility, and ability to obtain data in integral or differential form.
journal_name
J Pharm Scijournal_title
Journal of pharmaceutical sciencesauthors
Cakiryildiz C,Mehta PJ,Rahmen W,Schoenleber Ddoi
10.1002/jps.2600641024subject
Has Abstractpub_date
1975-10-01 00:00:00pages
1692-7issue
10eissn
0022-3549issn
1520-6017pii
S0022-3549(15)40415-0journal_volume
64pub_type
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journal_title:Journal of pharmaceutical sciences
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journal_title:Journal of pharmaceutical sciences
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journal_title:Journal of pharmaceutical sciences
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doi:
更新日期:1975-02-01 00:00:00
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