Republished: Recent advances: personalised use of current Crohn's disease therapeutic options.

abstract：:During the course of an obscure illness in a teenage girl it was eventually realized that the diagnosis was 'epidemic neuromyasthenia'. The illness which occurred between February and September 1976 was characterized by fatigue, pallor, headache, nuchal pain, alterations in mentation, dizziness, nausea and vomiting, p...

journal_title：Postgraduate medical journal

authors： Corridan JP

更新日期：1978-11-01 00:00:00

abstract：:Osteoporosis is a very common disorder, which results in an increase in fracture risk. The annual cost attributable to hip, vertebral, and wrist fractures in England and Wales is pound 1.7 billion. Significant mortality and morbidity are associated with osteoporotic fractures. The method that is most widely used for t...

journal_title：Postgraduate medical journal

authors： Christodoulou C,Cooper C

更新日期：2003-03-01 00:00:00

abstract：:The differing aspects of fibrocystic disease are presented. The various histological components making up the breast account for the variegated presentation of symptoms and findings. Pain, tenderness and nodularity represent the greatest problem with the former two prompting the patient to seek relief. The latter symp...

journal_title：Postgraduate medical journal

authors： Humphrey LJ,Estes NC

更新日期：1979-01-01 00:00:00

abstract：:A patient with a poorly differentiated clear cell adenocarcinoma of the ovary presenting as pyrexia of unknown origin is reported. Following resection of the tumour, her pyrexia resolved completely. ...

journal_title：Postgraduate medical journal

authors： Schofield PM,Kirsop BA,Reginald P,Harington M

更新日期：1985-02-01 00:00:00

abstract：:Relatively simple and rapid procedures have been developed for evaluating the local efficacy of vaginal antifungal agents in vivo in a vaginal candidiasis model in ovariectomized rats. The results of this investigation indicate that the model and methods described are quite suitable for screening potential antifungal ...

journal_title：Postgraduate medical journal

authors： McRipley RJ,Erhard PJ,Schwind RA,Whitney RR

更新日期：1979-09-01 00:00:00

abstract：:Non-invasive assessment of coronary artery patency has been attempted with different imaging modalities over the last few decades. The continuous motion of the heart, the respiratory movement, together with the small and tortuous nature of the coronary arteries, made this a technically challenging task. Over the last ...

journal_title：Postgraduate medical journal

authors： Yerramasu A,Venuraju S,Lahiri A

更新日期：2011-03-01 00:00:00

abstract：:Small bowel perforation occurs in up to 2 percent of patients with abdominal tuberculous. Patients present with an acute abdomen. Resection of the diseased segment and 18 months treatment with anti-tuberculosis drugs is recommended. ...

journal_title：Postgraduate medical journal

authors： Aston NO,de Costa AM

更新日期：1985-03-01 00:00:00

abstract：:A case of post-thyroidectomy hypothyroidism is reported. The patient became euthyroid in three consecutive pregnancies, reverting to hypothyroid within three months of delivery on each occasion. The alteration in thyroid status is attributed to pregnancy related changes in antibody titres, though the laboratory data t...

journal_title：Postgraduate medical journal

authors： Shankar P,Kilvert A,Fox C

更新日期：2001-09-01 00:00:00

abstract：:Bile acid, neutral sterol and faecal fat excretion was studied over a period of 9 weeks in a group of 16 healthy subjects before, during and after administration of fenfluramine. Statistical analysis revealed a significant increase in bile acid excretion during the drug phase (P less than 0.02); and during recovery pe...

journal_title：Postgraduate medical journal

authors： Sian MS,Rains AJ

更新日期：1979-03-01 00:00:00

abstract：:A previously healthy patient developed serologically-proven Yersinia pseudotuberculosis enterocolitis and made a complete recovery. Over a year later, further gastrointestinal symptoms developed and Crohn's disease was diagnosed. The possible relevance to the aetiology of Crohn's disease is discussed. ...

journal_title：Postgraduate medical journal

authors： Treacher DF,Jewell DP

更新日期：1985-02-01 00:00:00

abstract：:We report a case of severe chronic iron deficiency anaemia secondary to blood loss from gastric angiodysplasia. The clinical features, diagnosis and management of this uncommon condition are discussed. ...

journal_title：Postgraduate medical journal

authors： Tung KT,Millar AB

更新日期：1987-10-01 00:00:00

abstract：:Fourteen patients suffering from various degrees of bone dysplasia and mental handicap with superimposed neuroses or psychotic episodes are reported. Known biochemical and chromosomal causes are noted. Mental states associated with syndromes and mental malfunctioning or impairment because of skeletal defects or other ...

journal_title：Postgraduate medical journal

authors： Jancar J

更新日期：1977-08-01 00:00:00

abstract：:Four studies have been carried out on propofol in this department, one being part of a multicentre trial. The minimum induction dose in unpremedicated patients was found to be 2.5 mg/kg. Propofol has been shown to be an acceptable induction agent, although with an incidence of pain on injection which is much higher wh...

journal_title：Postgraduate medical journal

authors： Grounds RM,Morgan M,Lumley J

更新日期：1985-01-01 00:00:00

abstract：PURPOSE OF STUDY:The aim of the study is to describe the prevalence of illicit drug use in England and Wales using data from the UK Survey of Non-Medical Use of Prescription Drugs (NMURx) programme and to compare against the well-established Crime Survey England and Wales (CSEW). The rationale is that recreational and ...

journal_title：Postgraduate medical journal

authors： Ng FL,Rockhill K,Black J,May KP,Whittington MD,Wood DM,Dargan PI,Green JL

更新日期：2018-11-01 00:00:00

abstract：:Rhabdomyolysis is a rare but potentially fatal complication of hyperosmolar states. We report a case of severe hyperosmolar non-ketotic diabetic coma causing rhabdomyolysis in a young man. Despite very high levels of creatine kinase there was no detectable myoglobinuria. Creatine kinase estimation should be a standard...

journal_title：Postgraduate medical journal

authors： Trump D,O'Hanlon S,Rinsler M,Sharp P

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:There are wide variations in survival after cardiopulmonary resuscitation. The aim of this survey was to describe how equipment provision of resuscitation trolleys was deployed in a range of clinical ward areas. METHODS:The equipment in randomly selected resuscitation trolleys in all 14 South West Thames Re...

journal_title：Postgraduate medical journal

authors： Hogh L,Kane I,Bhalla A,Ward MC

更新日期：2005-06-01 00:00:00

abstract：:This paper reviews briefly the place of ipratropium bromide in the treatment of airways obstruction. Oxitropium bromide, a new quaternary ammonium compound derived from scopolamine was shown to be as effective a bronchodilator in a dose of 200 micrograms by inhalation as ipratropium bromide 80 micrograms in 20 patient...

journal_title：Postgraduate medical journal

authors： Anderson G

更新日期：1983-01-01 00:00:00

abstract：BACKGROUND:Post-radiation large vessel injury has not received as much attention as microvascular irradiation injury. A few studies have shown that common carotid intima-media thickness (IMT) is increased after radiotherapy to the head and neck. However, in most of these studies, the irradiated subjects also had other ...

journal_title：Postgraduate medical journal

authors： Shariat M,Alias NA,Biswal BM

更新日期：2008-11-01 00:00:00

abstract：:The characteristics of three combinations of thiopentone and etomidate [in the ratios of thiopentone (mg):etomidate (mg) of 5:1, 13:1 and 25:1] have been compared with the individual agents alone for the induction of anaesthesia. The incidence of pain on injection and abnormal movements was less with the combination c...

journal_title：Postgraduate medical journal

authors： Slater RM,Pollard BJ,Young TM,Hunt LP

更新日期：1990-07-01 00:00:00

abstract：:Clinical, endocrinological and computed tomographic features of three patients with unusual manifestations or complications of craniofacial involvement of fibrous dysplasia are presented. One patient with polyostotic fibrous dysplasia presented in late pregnancy with acute onset of bilateral optic nerve compression an...

journal_title：Postgraduate medical journal

authors： Daly BD,Chow CC,Cockram CS

更新日期：1994-01-01 00:00:00

abstract：:The Wolff-Parkinson-White syndrome can rarely present with pre-excited atrial fibrillation. In this condition the short refractory period of the accessory pathway can lead to rapid atrioventricular conduction. There is then a danger that at high heart rates the irregular broad complex tachycardia that results can dete...

journal_title：Postgraduate medical journal

authors： Adlam D,Azeem T

更新日期：2003-05-01 00:00:00

abstract：:The gross and microscopic features of an unusual case of neurocutaneous melanosis are described. This is an example of the rare association between a primary central nervous system malignant melanoma and a giant congenital melanocytic naevus of 'bathing trunk' distribution. ...

journal_title：Postgraduate medical journal

authors： Salisbury JR,Rose PE

更新日期：1989-06-01 00:00:00

abstract：:The insulin resistance/metabolic syndrome is characterised by the variable coexistence of hyperinsulinaemia, obesity, dyslipidaemia, and hypertension. The pathogenesis of the syndrome has multiple origins, but obesity and sedentary lifestyle coupled with diet and still largely unknown genetic factors clearly interact ...

journal_title：Postgraduate medical journal

authors： Kolovou GD,Anagnostopoulou KK,Cokkinos DV

更新日期：2005-06-01 00:00:00

abstract：:Although several modalities are available to investigate oesophageal motility disorders, manometry is the gold standard. The procedure is increasingly available in district general hospitals but the clinical utility of this investigation in this setting remains unclear. The aim in this study was to evaluate the use an...

journal_title：Postgraduate medical journal

authors： Ragunath K,Williams JG

更新日期：2002-01-01 00:00:00

abstract：:It has long been recognised that intensive efforts are needed to reform medical education in order to meet the future needs of populations worldwide. Pressure for changes to the organisation, content and delivery of both undergraduate and postgraduate medical education has greatly increased in the last two decades. Th...

journal_title：Postgraduate medical journal

authors： Parsell GJ,Bligh J

更新日期：1995-07-01 00:00:00

abstract：:Patients with Gardner's syndrome are increasingly found to have polyps on routine upper gastrointestinal endoscopy, and their risk of developing periampullary carcinoma is between 3-12%. We report a 45 year old man with Gardner's syndrome who presented with periampullary carcinoma 5 years after colectomy. Review of th...

journal_title：Postgraduate medical journal

authors： Sinha J,Williamson RC

更新日期：1988-11-01 00:00:00

abstract：:Three women were admitted to the surgical wards with acute gastro-intestinal symptoms and despite good clinical (pigmentation, hypotension) and biochemical (hyponatraemia, acidosis) evidence of Addisonian crisis had unnecessary investigations with delay in the diagnosis and appropriate management of this medical emerg...

journal_title：Postgraduate medical journal

authors： Small M,MacCuish AC,Thomson JA

更新日期：1987-05-01 00:00:00

abstract：:Three patients are described in whom one or more carotid territory transient ischaemic attacks (TIAs) were preceded by sneezing, straining, or bending over. It is argued that the mechanism involved dislodgment of embolic material from the site of carotid atheroma. This mechanism should be considered as an alternative ...

journal_title：Postgraduate medical journal

authors： Harrison MJ

更新日期：1999-03-01 00:00:00

abstract：:Infection with hepatitis B virus (HBV) is much more common in tropical than in temperate countries. Visitors to the tropics are thus at risk from HBV, though the degree of risk, and the routes of infection involved are uncertain. We report serological markers of HBV in two groups of 2nd World War soldiers, who served ...

journal_title：Postgraduate medical journal

authors： Gill GV,Bell DR,Vandervelde EM

更新日期：1991-01-01 00:00:00

abstract：:Largyngotracheal and pharyngoesophageal tears following minor blunt trauma to the neck are uncommon. A child with such an injury is reported and the modes of diagnosis and management are discussed. Patients may initially present with minimal signs and symptoms, but their condition may deteriorate rapidly or insidiousl...

journal_title：Postgraduate medical journal

authors： Back GW,Banfield G

更新日期：1999-09-01 00:00:00