The changing context of undergraduate medical education.

abstract：:Chemotherapy-induced nausea and vomiting (CINV) remains one of the most debilitating toxicities associated with cancer treatment. In recent decades, significant strides have been made in our understanding of the pathophysiology of CINV, making way to more effective targeted pharmacotherapies, especially 5-hydroxytrypt...

journal_title：Postgraduate medical journal

authors： Tageja N,Groninger H

更新日期：2016-01-01 00:00:00

abstract：:We describe two patients with diabetes mellitus and associated neuropathy, who presented with painless foot swelling and no history of trauma. X-Rays revealed recent underlying fractures-in one of a metatarsus, and the other of a proximal phalanx. These were assumed to be 'stress' fractures unassociated with pain beca...

journal_title：Postgraduate medical journal

authors： Gill G,Benbow S,Tesfaye S,Kaczmarczyk E,Kaye L

更新日期：1997-04-01 00:00:00

abstract：:Various tumours, in particular lymphomas, have been reported in association with azathioprine treatment, both after renal transplantation and in other conditions. A case is reported here of acute myeloid leukaemia associated with azathioprine therapy for rheumatoid arthritis, and this is now the third case reported in...

journal_title：Postgraduate medical journal

authors： Gilmore IT,Holden G,Rodan KS

更新日期：1977-03-01 00:00:00

abstract：BACKGROUND:Right ventricular (RV) fractional area change and tricuspid annular plane systolic excursion (TAPSE) are recognised methods for assessing RV function. However, the way in which these variables are affected by varying degrees of pulmonary hypertension (PH) has not been well characterised. METHODS:RV end-syst...

journal_title：Postgraduate medical journal

authors： López-Candales A,Dohi K,Rajagopalan N,Edelman K,Gulyasy B,Bazaz R

更新日期：2008-01-01 00:00:00

abstract：:Disc herniation at the thoracic the spine level is more common than generally thought. Localisation of pain may be vague and may erroneously point to cardiopulmonary, gastrointestinal, genito-urinary or even psychiatric disease. Magnetic resonance imaging is the investigation of choice, especially if spinal cord compr...

journal_title：Postgraduate medical journal

authors： Pal B,Johnson A

更新日期：1997-07-01 00:00:00

abstract：:The treatment of renal anaemia by recombinant human erythropoietin (EPO) is now well established. Several studies have examined the pharmacokinetics and efficacy of the drug given intravenously, intraperitoneally and subcutaneously and there is increasing evidence that the subcutaneous route has several advantages inc...

journal_title：Postgraduate medical journal

authors： Macdougall IC,Hutton RD,Coles GA,Williams JD

更新日期：1991-01-01 00:00:00

abstract：:We describe the case of an acromegalic woman with primary infertility who was treated with clomiphene, and subsequently developed pituitary apoplexy. ...

journal_title：Postgraduate medical journal

authors： Walker AB,Eldridge PR,MacFarlane IA

更新日期：1996-03-01 00:00:00

abstract：:The toxic effects of paracetamol in overdose quantities are well recognised but the occurrence of anaphylactoid reactions to paracetamol is infrequently identified by consumers and health care professionals. Nevertheless adverse reactions to this drug, even in therapeutic doses, can have fatal or near fatal consequenc...

journal_title：Postgraduate medical journal

authors： Ayonrinde OT,Saker BM

更新日期：2000-08-01 00:00:00

abstract：BACKGROUND:Current treatment for osteoarthritis (OA) is limited. Many patients with OA of the hand have areas of tender subcutaneous thickening in the forearm and upper scapular region. A pilot study showed an improvement in pain from OA at the first carpometacarpal joint after injection of such areas with 0.5% sodium ...

journal_title：Postgraduate medical journal

authors： Smith AS,Doré CJ,Dennis L,Julius A,Mackworth-Young CG

更新日期：2010-06-01 00:00:00

abstract：:Serum thyrotrophin has been measured before and after the intravenous administration of 200 micrograms of thyrotrophin-releasing hormone in 91 white subjects (33 stable diabetic patients and 58 healthy controls), none of whom had any clinical evidence of thyroid or pituitary dysfunction. Seven of the diabetic subjects...

journal_title：Postgraduate medical journal

authors： Small M,Cohen HN,MacLean JA,Beastall GH,MacCuish AC

更新日期：1986-06-01 00:00:00

abstract：:Candida albicans peritonitis developed in a 48-year-old man with a perforated gastric ulcer who subsequently was treated with intravenous amphotericin B. The drug penetrated well into the inflamed peritoneal cavity and eradicated the organism from the peritoneal fluid. Nevertheless, at post-mortem, Candida organisms w...

journal_title：Postgraduate medical journal

authors： Peterson LR,Kelty RH,Hall WH,Votava HJ

更新日期：1978-05-01 00:00:00

abstract：:We report a case of endocarditis associated with a highly gentamicin-resistant enterococcus that failed to respond to conventional antibiotic combination therapy. Clinical resolution was achieved following cardiac surgery and antimicrobial treatment dictated by in vitro testing of the patient's organism. Laboratories ...

journal_title：Postgraduate medical journal

authors： Holliman R,Smyth E

更新日期：1989-06-01 00:00:00

abstract：OBJECTIVES:Obesity is an increasing problem in the UK and bariatric surgery is likely to increase in volume in the future. While substantial weight loss is the primary outcome following bariatric surgery, the effect on obesity-related morbidity, mortality and quality of life (QOL) is equally important. This study repor...

journal_title：Postgraduate medical journal

authors： Titi M,Jenkins JT,Modak P,Galloway DJ

更新日期：2007-07-01 00:00:00

abstract：:Secondary hyperkalaemic paralysis is a rare condition often mimicking the Guillain-Barré syndrome. There have been a few case reports of hyperkalaemia caused by renal failure, trauma, and drugs where the presentation has been with muscle weakness. A case of hyperkalaemic paralysis caused by an angiotensin converting e...

journal_title：Postgraduate medical journal

authors： Dutta D,Fischler M,McClung A

更新日期：2001-02-01 00:00:00

abstract：:A 27 year old woman with hepato-lenticular degeneration (Wilson's disease) was found to have primary hepatocellular carcinoma (PHC) three and a half years after she was started on treatment with D-penicillamine. The tumour was resected since when she has remained well. Her liver function tests were normal throughout t...

journal_title：Postgraduate medical journal

authors： Guan R,Oon CJ,Wong PK,Foong WC,Wee A

更新日期：1985-04-01 00:00:00

abstract：:The abnormalities of erythrocytes, leucocytes, thrombocytes and coagulation that have been reported, particularly in more recent years, to be associated with hyperthyroidism are surveyed. Several areas are highlighted where further investigations could lead to clinically useful insights, improved information about the...

journal_title：Postgraduate medical journal

authors： Ford HC,Carter JM

更新日期：1988-10-01 00:00:00

abstract：:Fasting plasma and urinary calcium and urinary hydroxyproline are known to rise at the menopause, reflecting increased bone resorption. Oestradiol valerate and cyclic oestradiol valerate/DL-norgestrel are shown to reduce this evidence of increased bone loss. It is concluded that these preparations will be effective in...

journal_title：Postgraduate medical journal

authors： Crilly RG,Marshall DH,Nordin BE

更新日期：1978-01-01 00:00:00

abstract：:The Mirizzi syndrome is an unusual presentation of gallstones which occurs when a gallstone becomes impacted in either Hartmann's pouch of the gallbladder or the cystic duct, causing obstruction of the common hepatic duct by extrinsic compression. The diagnosis of this syndrome is of importance because surgery in its ...

journal_title：Postgraduate medical journal

authors： Pemberton M,Wells AD

更新日期：1997-08-01 00:00:00

abstract：BACKGROUND:Circulating nitric oxide (NO) and lipid levels are closely associated with coronary artery disease (CAD). It is unclear whether the rs1799983 polymorphism in endothelial nitric oxide synthase (NOS3) gene is associated with plasma levels of NO and lipids. This systematic review and meta-analysis (Preferred Re...

journal_title：Postgraduate medical journal

authors： Luo Z,Jia A,Lu Z,Muhammad I,Adenrele A,Song Y

更新日期：2019-07-01 00:00:00

abstract：:Submucosal dissection of the oesophagus is a rare oesophageal disorder. We report a patient who had recurrent episodes of dissection and achalasia. Both recurrence and the association with achalasia are to our knowledge unique. ...

journal_title：Postgraduate medical journal

authors： Hooper TL,Gholkar J,Smith SR,Manns JJ,Moussalli H

更新日期：1986-10-01 00:00:00

abstract：:A woman aged 35 years from the Philippines presented with epigastric discomfort associated with an epigastric mass. On examination the liver was markedly enlarged. ...

journal_title：Postgraduate medical journal

authors： Kreel L

更新日期：1989-04-01 00:00:00

abstract：:In recent years, the short Synacthen test (SS) has become the most widely used test to assess adrenal reserve. Despite its frequent use, there are still several areas related to the short Synacthen test (SST), which have no consensus including the optimum sampling times, that is, whether a 60 min post-Synacthen admini...

journal_title：Postgraduate medical journal

authors： Dineen R,Mohamed A,Gunness A,Rakovac A,Cullen E,Barnwell N,Neary C,Behan LA,Boran G,Gibney J,Sherlock M

更新日期：2020-02-01 00:00:00

abstract：:There is evidence that acetylcholine antagonists at the neuromuscular junction and elsewhere can act by blocking the ionic channels opened by acetylcholine as well as by competing with acetylcholine for receptor sites. This type of uncompetitive antagonism can be distinguished from competitive antagonism in various wa...

journal_title：Postgraduate medical journal

authors： Rang HP

更新日期：1981-01-01 00:00:00

abstract：:Primary gastric lymphoma is a rare tumour. It is thought that low grade gastric mucosa associated lymphoid tissue lymphoma has not been previously reported to occur in a patient with gastrojejunostomy. This report describes such a case. The patient presented with bleeding from non-healing stomal ulcers. The ulcers hea...

journal_title：Postgraduate medical journal

authors： Misra SP,Misra V,Dwivedi M

更新日期：2005-02-01 00:00:00

abstract：:Quantitative lipoprotein level data was obtained from healthy subjects and patients with ischaemic heart disease or peripheral vascular disease in four European communities. Hypertriglyceridaemia, due mainly to an increase in VLDL triglyceride, was commoner in London and Uppsala than in Naples and Geneva. In three com...

journal_title：Postgraduate medical journal

authors： Lewis B,Carlson LA,Mancini M,Micheli H

更新日期：1975-01-01 00:00:00

abstract：:A 33-year-old housewife with a 14-year history of relapsing polyneuropathy of unknown cause who has apparently responded to azathioprine therapy is described. The place of this form of treatment in idiopathic polyneuropathy is discussed. ...

journal_title：Postgraduate medical journal

authors： Pentland B

更新日期：1980-10-01 00:00:00

abstract：:Three patients with lung carcinoid related Cushing's syndrome (LCRCS) treated at Frenchay Hospital, Bristol between 1984 and 1994 are described. The first patient presented with hyperpigmentation 13 years after bilateral adrenalectomy. The second patient had no recurrence or metastases 14 years after removal of a typi...

journal_title：Postgraduate medical journal

authors： Amer KM,Ibrahim NB,Forrester-Wood CP,Saad RA,Scanlon M

更新日期：2001-07-01 00:00:00

abstract：:The new formulation of propofol appears to be approximately equipotent to the previous formulation when used as an infusion to supplement nitrous oxide anaesthesia in patients premedicated with morphine. Preliminary haemodynamic studies indicate that the emulsion formulation causes more arterial hypotension than the o...

journal_title：Postgraduate medical journal

authors： Coates DP,Prys-Roberts C,Spelina KR,Monk CR,Norley I

更新日期：1985-01-01 00:00:00

abstract：:Herniation of a thoracic disc in an acromegalic giant is reported. Degenerative changes in the spine in association with dorsal kyphosis, and the additional strain, resulted in the disc prolapse. ...

journal_title：Postgraduate medical journal

authors： Chhang WH,Sharma BS,Dash RJ,Kak VK

更新日期：1989-07-01 00:00:00

abstract：:A patient with long-standing ischaemic heart disease and severe low output congestive cardiac failure received numerous diuretics, which gradually became ineffective. Resistant oedema was treated by adding demeclocycline to the current diuretic regime of frusemide and metolazone. Diuresis resulted, oedema disappeared ...

journal_title：Postgraduate medical journal

authors： Bonser RS,Ghose RR

更新日期：1980-02-01 00:00:00