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Recent progress in human telomere RNA structure and function.

Abstract：

:Human telomeric DNA is transcribed into telomeric RNA in cells. Telomeric RNA performs the fundamental biological functions such as regulation and protection of chromosome ends. This digest highlights the human telomere RNA G-quadruplex structures, telomere RNA functions, G-quadruplex-binding small molecules, and future prospects.

journal_name

Bioorg Med Chem Lett

journal_title

Bioorganic & medicinal chemistry letters

authors

Xu Y

doi

10.1016/j.bmcl.2018.06.021

subject

Has Abstract

pub_date

2018-08-15 00:00:00

pages

2577-2584

issue

15

eissn

0960-894X

issn

1464-3405

pii

S0960-894X(18)30510-9

journal_volume

28

pub_type

杂志文章,评审

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