Metrizamide myelography in patients with small cell carcinoma of the lung suspected of meningeal carcinomatosis.

abstract：:Chemotherapy is often omitted in elderly patients with glioblastoma multiforme due to a fear of side effects. We applied metronomic chemotherapy with low-dose temozolomide and celecoxib (LD-TEM/CEL) during and after external beam radiotherapy (EBRT) and here report on how this regimen compares to standard temozolomide...

journal_title：Journal of neuro-oncology

authors： Welzel G,Gehweiler J,Brehmer S,Appelt JU,von Deimling A,Seiz-Rosenhagen M,Schmiedek P,Wenz F,Giordano FA

更新日期：2015-09-01 00:00:00

abstract：:Anaplastic oligodendroglioma (AO) is an uncommon intracranial tumor and prognosis is poor. In this study, we assessed the factors affecting the prognosis of AO patients. Seventy AO patients were recruited from 2001 to 2006 in Shanghai Huashan Hospital of Fudan University; all were treated surgically. Kaplan-Meier surv...

journal_title：Journal of neuro-oncology

authors： Yang LS,Huang FP,Zheng K,Zhang HS,Zhou X,Bao XH,Zheng JJ,Chang C,Zhou LF

更新日期：2010-10-01 00:00:00

abstract：:To explore the antitumor mechanism of bacterial cytosine deaminase plus 5-fluorocytosine (CD/5-FCyt) in combination with interferons (IFNs), glioma cells were transduced with recombinant retroviruses expressing CD. The transduced glioma cells become sensitive to the nontoxic prodrug 5-FCyt. Apoptosis, DNA damage, byst...

journal_title：Journal of neuro-oncology

authors： Wang ZH,Samuels S,Gama Sosa MA,Kolodny EH

更新日期：1998-02-01 00:00:00

abstract：:The diagnosis of a high-grade glioma usual is followed by functional impairment(s), cognitive decline and an impaired psycho-social well-being. This might well have a significant and negative impact on the health related quality of life. The purpose of this study was to explore physical activity levels, prevalence and...

journal_title：Journal of neuro-oncology

authors： Piil K,Jakobsen J,Christensen KB,Juhler M,Jarden M

更新日期：2015-09-01 00:00:00

abstract：:Twenty-eight patients with malignant brain tumors (16 with primary brain tumors and 12 with brain metastases) progressing after cranial irradiation with or without chemotherapy received varying doses of intracarotid VP-16. Courses of therapy were repeated every 4 weeks along with computerized axial tomography scan and...

journal_title：Journal of neuro-oncology

authors： Feun LG,Lee YY,Yung WK,Savaraj N,Wallace S

更新日期：1987-01-01 00:00:00

abstract：:From 1974 to 1992, 63 patients diagnosed with low-grade pure or mixed oligo-astrocytoma were seen and treated at our institution. All patients underwent CT scan pre-operatively. There were 20 female and 43 males ranging in age from 12 to 73 years (median age of 33 years). 15 patients had a stereotactic biopsy as the o...

journal_title：Journal of neuro-oncology

authors： Bahary JP,Villemure JG,Choi S,Leblanc R,Olivier A,Bertrand G,Souhami L,Tampieri D,Hazel J

更新日期：1996-02-01 00:00:00

abstract：:Proteasome activity is essential during cAMP-induced terminal differentiation of a murine neuroblastoma cell line (NBP2). However, the mechanisms through which proteasome affects NBP2 differentiation have not been characterized. We hypothesized that proteasome is required to implement the differentiation-mediated effe...

journal_title：Journal of neuro-oncology

authors： Nahreini P,Andreatta C,Hanson A,Prasad KN

更新日期：2003-05-01 00:00:00

abstract：:Vascular endothelial growth factor (VEGF) and its receptors (VEGFR) are central components in the development and progression of glioblastoma. To investigate if genetic variation in VEGF and VEGFR2 is associated with glioblastoma prognosis, we examined blood samples from 154 glioblastoma cases collected in Sweden and ...

journal_title：Journal of neuro-oncology

authors： Sjöström S,Wibom C,Andersson U,Brännström T,Broholm H,Johansen C,Collatz-Laier H,Liu Y,Bondy M,Henriksson R,Melin B

更新日期：2011-09-01 00:00:00

abstract：:Disparities in American health care based on socially-defined patient characteristics such as race, ethnicity, and socioeconomic position are well-documented. We review differences and disparities in incidence, pathobiology, processes and outcomes of care, and survival based on social factors for brain tumors of all h...

journal_title：Journal of neuro-oncology

authors： Curry WT Jr,Barker FG 2nd

更新日期：2009-05-01 00:00:00

abstract：:Sacral chordoma is a vessel-rich and infiltrative tumor, but the fundamental knowledge of its biological behavior remains unknown. This study was designed to investigate the expression levels and contributions of vascular endothelial growth factor (VEGF) and matrix metalloproteinase-9 (MMP-9) in the angiogenesis and r...

journal_title：Journal of neuro-oncology

authors： Chen KW,Yang HL,Lu J,Wang GL,Ji YM,Wu GZ,Zhu LF,Liu JY,Chen XQ,Gu YP

更新日期：2011-02-01 00:00:00

abstract：:Primary brain tumor patients experience high levels of distress. The purpose of this cross-sectional, retrospective study is to evaluate the level and different sources of psychosocial distress and how these pertain to health-related quality of life (HRQoL). The Primary and Recurrent Glioma registry at Duke's The Pres...

journal_title：Journal of neuro-oncology

authors： Randazzo DM,McSherry F,Herndon JE 2nd,Affronti ML,Lipp ES,Flahiff C,Miller E,Woodring S,Freeman M,Healy P,Minchew J,Boulton S,Desjardins A,Vlahovic G,Friedman HS,Keir S,Peters KB

更新日期：2017-09-01 00:00:00

abstract：:Meningioma is a common intracranial tumor, originating from the meninges of the skull or spinal canal. Most meningiomas are benign tumors, however atypical or anaplastic tumors can be found in 6% of cases. Patients with asymptomatic small benign meningiomas can be followed without therapy, but in symptomatic patients ...

journal_title：Journal of neuro-oncology

authors： Sioka C,Kyritsis AP

更新日期：2009-03-01 00:00:00

abstract：:Central neurocytoma was originally described as a rare benign neuronal tumor. However, progression and local recurrences after surgery are well recognized. Stereotactic radiosurgery is another option for treatment of CN. In order to evaluate the efficacy of SRS, we performed a quantitative systematic review of the ava...

journal_title：Journal of neuro-oncology

authors： Park HK,Steven D C

更新日期：2012-05-01 00:00:00

abstract：:Macrophages play an important role in the regulation of malignant tumors. Although glioma contains abundance of macrophages, their role in apoptosis of glioma is not known. We stimulated macrophages with lipopolysaccharide and culture supernatants of activated macrophages were collected to treat glioma cells. The resu...

journal_title：Journal of neuro-oncology

authors： Chen GG,Chu YS,Chak EC,Leung BC,Poon WS

更新日期：2002-05-01 00:00:00

abstract：:One objection to using cell cultures for studying the proliferation of tumors is the potential for phenotypic changes that may occur in vitro. Here, we compared the antigen pattern expression of cultured meningioma cells with that of the primary tumor. Cell cultures established from 9 intracranial meningiomas and depa...

journal_title：Journal of neuro-oncology

authors： Pallini R,Casalbore P,Mercanti D,Maggiano N,Larocca LM

更新日期：2000-08-01 00:00:00

abstract：:Recurrent gliomas are most often treated by chemotherapy. However, these tumors typically acquire resistance to most drugs administered, and patients will usually die of recurrent tumor. Factors which may play a role include overexpression of putative multidrug resistance genes, such as the multidrug resistance gene 1...

journal_title：Journal of neuro-oncology

authors： Liang BC

更新日期：1996-08-01 00:00:00

abstract：:Thirty-one patients with metastatic brain tumors that either failed to respond or recurred after conventional therapy were treated by intra-arterial infusion of 100 mg/m2 of 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) into either a carotid or vertebral artery. Five patients (three with lung cancer, one with breast can...

journal_title：Journal of neuro-oncology

authors： Cascino TL,Byrne TN,Deck MD,Posner JB

更新日期：1983-01-01 00:00:00

abstract：:The aim of the study was to examine associations between occupational exposure to metals and meningioma risk in the international INTEROCC study. INTEROCC is a seven-country population-based case-control study including 1906 adult meningioma cases and 5565 population controls. Incident cases were recruited between 200...

journal_title：Journal of neuro-oncology

authors： Sadetzki S,Chetrit A,Turner MC,van Tongeren M,Benke G,Figuerola J,Fleming S,Hours M,Kincl L,Krewski D,McLean D,Parent ME,Richardson L,Schlehofer B,Schlaefer K,Blettner M,Schüz J,Siemiatycki J,Cardis E

更新日期：2016-12-01 00:00:00

abstract：:Despite total macroscopic resection of meningiomas relapses do occur in these tumours, possibly because of microscopic clusters of neoplastic cells left in the dura mater or in the arachnoid membrane. The invasiveness of the neoplastic cells of human meningiomas has been related to expression of matrix-metalloproteina...

journal_title：Journal of neuro-oncology

authors： Barresi V,Vitarelli E,Tuccari G,Barresi G

更新日期：2011-04-01 00:00:00

abstract：:When surgery and radiation are no longer treatment options, salvage systemic therapy has been used for recurrent meningiomas with little compelling evidence to suggest effectiveness. Patients with surgery and radiation refractory recurrent meningiomas were treated with the oral multifunctional tyrosine kinase inhibito...

journal_title：Journal of neuro-oncology

authors： Raizer JJ,Grimm SA,Rademaker A,Chandler JP,Muro K,Helenowski I,Rice L,McCarthy K,Johnston SK,Mrugala MM,Chamberlain M

更新日期：2014-03-01 00:00:00

abstract：:Measurement of oxygen pressure (pO2) in tumor tissue is important, because pO2 is a major factor for radiosensitivity in malignant glioma treatment. We attempted to elucidate the changes in pO2 level in glioblastoma tissue of patients under various conditions. Eighteen patients with newly diagnosed glioblastoma were r...

journal_title：Journal of neuro-oncology

authors： Beppu T,Kamada K,Yoshida Y,Arai H,Ogasawara K,Ogawa A

更新日期：2002-05-01 00:00:00

abstract：:Combination of procarbazine, lomustine and vincristine (PCV) with radiation therapy (RT) has been associated with longer survival in patients with anaplastic oligodendroglioma (AO) and anaplastic oligoastrocytoma (AOA), especially in those with chromosome 1p/19q codeletion. We report a multicenter retrospective study ...

journal_title：Journal of neuro-oncology

authors： Minniti G,Arcella A,Scaringi C,Lanzetta G,Di Stefano D,Scarpino S,Pace A,Giangaspero F,Osti MF,Enrici RM

更新日期：2014-01-01 00:00:00

abstract：:A prospective study was performed in patients treated with cisplatin to evaluate the occurrence and degree of central, peripheral and autonomic neuropathy and to determine the most accurate method to study this neuropathy. Twelve patients were examined before, during and after treatment. Evaluation included neurologic...

journal_title：Journal of neuro-oncology

authors： Boogerd W,ten Bokkel Huinink WW,Dalesio O,Hoppenbrouwers WJ,van der Sande JJ

更新日期：1990-12-01 00:00:00

abstract：:Dysembryoplastic neuroepithelial tumors (DNET) are usually benign lesions that arise in cortical regions and are discovered after new onset of seizure. These lesions have many different imaging characteristics. We report a patient with a presumed low-grade medial temporal lobe lesion that was followed for many years w...

journal_title：Journal of neuro-oncology

authors： Jensen RL,Caamano E,Jensen EM,Couldwell WT

更新日期：2006-05-01 00:00:00

abstract：PURPOSE:The purpose of our study was to determine the statistical significance of thresholds of relative cerebral blood volume (rCBV), apparent diffusion coefficient (ADC) and ADC ratios in grading cerebral gliomas. MATERIALS AND METHODS:In this retrospective study, 51 patients with histopathologically confirmed prima...

journal_title：Journal of neuro-oncology

authors： Arvinda HR,Kesavadas C,Sarma PS,Thomas B,Radhakrishnan VV,Gupta AK,Kapilamoorthy TR,Nair S

更新日期：2009-08-01 00:00:00

abstract：:Despite the accumulating evidences of high chemosensitivity especially in anaplastic oligodendrogliomas with loss of chromosomes 1p and 19q, the optimal management strategy for low-grade tumors using the 1p/19q information remains controversial. We have treated all low-grade oligodendrogliomas by a chemotherapy-preced...

journal_title：Journal of neuro-oncology

authors： Iwadate Y,Matsutani T,Hasegawa Y,Shinozaki N,Higuchi Y,Saeki N

更新日期：2011-05-01 00:00:00

abstract：:Choroid plexus carcinoma (CPC) arising in the infant poses several treatment dilemmas. The tumor is often not totally resectable at presentation given its large size and tendency to invade adjacent brain. Because of its predisposition to regrow and metastasize, some form of postoperative cytotoxic therapy is required....

journal_title：Journal of neuro-oncology

authors： Allen J,Wisoff J,Helson L,Pearce J,Arenson E

更新日期：1992-01-01 00:00:00

abstract：:The aim of this investigation was to define characteristic properties of cellular energy metabolism in meningiomas in vitro dependent on the histological subtype. We analysed marker enzymes of representative metabolic pathways localized in the mitochondria (respiratory chain, citric acid cycle, beta-oxidation of fatty...

journal_title：Journal of neuro-oncology

authors： Herting B,Meixensberger J,Roggendorf W,Reichmann H

更新日期：2003-11-01 00:00:00

abstract：:Twenty-eight patients who were previously treated by aggressive surgery and radiation and were diagnosed with supratentorial malignant gliomas received a combination of nimustine hydrochloride; 1-(4-amino-2-methyl-5-pyrimidinyl) methyl-3-(2-chloroethyl)-3-nitrosourea hydrochloride (ACNU), cisplatin and etoposide (ACE ...

journal_title：Journal of neuro-oncology

authors： Beppu T,Yoshida Y,Arai H,Wada T,Suzuki M,Ogawa A,Hakozaki S,Kubo N

更新日期：2000-09-01 00:00:00

abstract：:Approximately half of surgically-treated patients with low-grade-glioma (LGG) suffer recurrence or metastasis. Currently there is no effective drug treatment. While the selective COX-2 inhibitor celecoxib showed anti-neoplastic activity against several malignant tumors, its effects against LGG remain to be elucidated....

journal_title：Journal of neuro-oncology

authors： Sato A,Mizobuchi Y,Nakajima K,Shono K,Fujihara T,Kageji T,Kitazato K,Matsuzaki K,Mure H,Kuwayama K,Sumi A,Saya H,Sampetrean O,Nagahirao S

更新日期：2017-04-01 00:00:00