Interferon receptors during treatment of chronic hepatitis B with interferon.

abstract：:Humans and Helicobacter pylori have evolved and adapted over tens of thousands of years. Yet peptic ulcer disease appeared to be rare prior to the 19th century. The prevalence of peptic ulcer disease increased between 1850 and 1900 and culminated in a cohort at high risk that was born at the end of the 19th century. T...

journal_title：Journal of gastroenterology and hepatology

authors： Roberts-Thomson IC

更新日期：2018-07-01 00:00:00

abstract：:A 54-year-old woman who was being treated with 10 million units (mu) of natural interferon (IFN)-alpha per day for chronic active hepatitis C at a local clinic, developed coma on the fourth day of treatment. On admission to Yamagata University Hospital, she was still in a state of semicoma with severe hyponatraemia (1...

journal_title：Journal of gastroenterology and hepatology

authors： Mabe K,Shinzawa H,Yamatani K,Takeda T,Ishibashi M,Yamada N,Misawa H,Wakabayashi H,Togashi H,Takahashi T

更新日期：1997-07-01 00:00:00

abstract：:Although the incidence of bleeding from gastric varices is relatively low (10%-36%), the bleeding is massive once it has occurred and it increases the patient's mortality. The management of esophageal variceal bleeding is highly differentiated with several effective treatments available. In contrast, bleeding from gas...

journal_title：Journal of gastroenterology and hepatology

authors： Hashizume M,Akahoshi T,Tomikawa M

更新日期：2011-01-01 00:00:00

abstract：:Ceftriaxone-associated sludge has been a fascinating story. The occurrence is novel and unique. It has produced a model of gall-bladder sludge in humans. This phenomenon has taught us a great deal about biliary lipid and organic anion excretion by the liver, and the physical chemistry of calcium and calcium sensitive ...

journal_title：Journal of gastroenterology and hepatology

authors： Kim YS,Kestell MF,Lee SP

更新日期：1992-11-01 00:00:00

abstract：BACKGROUND AND AIM:We recently conducted a randomized placebo-controlled trial on the efficacy and safety of rikkunshito, a standardized Japanese herbal medicine, for the treatment of functional dyspepsia (FD). The present post-hoc study aimed to evaluate the differences in clinical characteristics between responders a...

journal_title：Journal of gastroenterology and hepatology

authors： Togawa K,Matsuzaki J,Kobayakawa M,Fukushima Y,Suzaki F,Kasugai K,Nishizawa T,Naito Y,Hayakawa T,Kamiya T,Andoh T,Yoshida H,Tokura Y,Nagata H,Mori M,Kato K,Hosoda H,Takebayashi T,Miura S,Uemura N,Joh T,Hibi T,S

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND AND AIM:Although several meta-analyses suggested that sequential therapy (SQT) is superior to standard triple therapy (STT) for the eradication of Helicobacter pylori, these results were mainly based on the studies from Italy. The aim of this study was to assess the efficacy of 10-day SQT for H. pylori infec...

journal_title：Journal of gastroenterology and hepatology

authors： Yoon H,Lee DH,Kim N,Park YS,Shin CM,Kang KK,Oh DH,Jang DK,Chung JW

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND AND AIM:The oral manifestations of familial adenomatous polyposis (FAP) have been reported in the recent literature. Therefore, there has been growing interest in the characterization of the dento-osseous anomalies because they may precede colorectal cancer and may be used as a diagnostic marker. This system...

journal_title：Journal of gastroenterology and hepatology

authors： Almeida FT,Pachêco-Pereira C,Porporatti AL,Flores-Mir C,Leite AF,De Luca Canto G,Guerra EN

更新日期：2016-03-01 00:00:00

abstract：:The prevalence of patients presenting with fatty liver disease (FLD) in China has approximately doubled over the past two decades. At present, FLD, which is typically diagnosed by imaging, is highly prevalent (≈ 27% urban population) in China and is mainly related to obesity and metabolic syndrome (MetS). However, the...

journal_title：Journal of gastroenterology and hepatology

authors： Fan JG

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND AND AIM:Opioid-induced constipation (OIC) is a frequent adverse event (AE) that impairs patients' quality of life (QOL). Peripherally acting μ-opioid receptor antagonists (PAMORAs) have been recognized as a treatment option for OIC, but the effect consistent across the studies has not been evaluated. METHOD...

journal_title：Journal of gastroenterology and hepatology

authors： Nishie K,Yamamoto S,Yamaga T,Horigome N,Hanaoka M

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND AND AIMS:According to reports in Japanese patients, 1 week of Helicobacter pylori eradication therapy alone is not adequate for healing of gastric ulcers; 7-8 weeks of anti-ulcer therapy are subsequently required. We compared a gastroprotective drug, sofalcone, and an H(2)-receptor antagonist, cimetidine, in...

journal_title：Journal of gastroenterology and hepatology

authors： Higuchi K,Watanabe T,Tanigawa T,Tominaga K,Fujiwara Y,Arakawa T

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND AND AIM:Colorectal cancer screening is recommended for average-risk persons beginning at age 50. However, information about the incidence and risk factors of precursor adenoma in preceding decades is limited. The aim of this study was to determine the prevalence and risk factors of colorectal adenoma in pers...

journal_title：Journal of gastroenterology and hepatology

authors： Chung SJ,Kim YS,Yang SY,Song JH,Park MJ,Kim JS,Jung HC,Song IS

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND AND AIMS:The relationship between gastroesophageal reflux disease and sliding hernia is controversial, especially following distal partial gastrectomy in patients with gastric cancer. The aim of this study was to examine the relationship between gastroesophageal reflux disease and sliding hernia of the esoph...

journal_title：Journal of gastroenterology and hepatology

authors： Fujiwara Y,Nakao K,Inoue T,Koishi K,Nishio Y,Yagyu R,Nakagawa K,Yamamura T

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND AND AIM:Hepatic arterial infusion (HAI) chemotherapy has a number of limitations, including a low rate of complete response and frequent extrahepatic recurrence, in colorectal cancer patients with non-resectable hepatic metastases. METHODS:Twenty-nine colorectal cancer patients with non-resectable hepatic m...

journal_title：Journal of gastroenterology and hepatology

authors： Kim JC,Kim HC,Lee KH,Yu CS,Kim TW,Chang HM,Ryu MH,Kim JH,Ha HK,Lee MG

更新日期：2006-06-01 00:00:00

abstract：:The identification of activated hepatic stellate cells and related cell types as key fibrogenic effectors during liver injury has led to intense evaluation of transcriptional events underlying their behavior. While initial studies focused on characterizing interactions between transcription factors and regulatory regi...

journal_title：Journal of gastroenterology and hepatology

authors： Friedman SL

更新日期：2006-10-01 00:00:00

abstract：:Three clinicopathological phases of chronic hepatitis B virus (HBV) infection are identified. First, is immune tolerance of HBV. High levels of viraemia are associated with normal alanine aminotransferase (ALT) levels and minimal histological lesions. More than 30-40% of hepatocytes have the hepatitis B core antigen (...

journal_title：Journal of gastroenterology and hepatology

authors： Chu CM,Liaw YF

更新日期：1997-10-01 00:00:00

abstract：INTRODUCTION:The aim of the present study was to determine whether rats with moderately fatty liver could withstand a 90% hepatectomy, which rats with normal livers can survive. MATERIAL AND METHODS:Nine-week-old male Wistar rats were used. Normal rat chow was fed to the normal liver group, and fat-enriched rat chow w...

journal_title：Journal of gastroenterology and hepatology

authors： Morioka D,Watanabe K,Makino H,Saito S,Ueda M,Kubota T,Sekido H,Matsuo K,Ichikawa Y,Endo I,Togo S,Shimada H

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND AND AIMS:Aberrant right subclavian artery (ARSA) is the most common congenital anomaly of the aortic arch occurring in 0.4-2.0% of the general population. Instead of arising from the brachiocephalic artery, the ARSA arises as the last branch from the aortic arch. The aim of this study was to determine the pr...

journal_title：Journal of gastroenterology and hepatology

authors： Yusuf TE,Levy MJ,Wiersema MJ,Clain JE,Harewood GC,Rajan E,Topazian MD,Wang KK

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND:Cyanoacrylate injection is highly effective and is regarded as the treatment of choice in bleeding gastric varices in Europe, but intravenous injection of cyanoacrylate is not allowed in the USA and Japan because it may cause embolisms in other organs. Accordingly, we developed a new endoscopic combined trea...

journal_title：Journal of gastroenterology and hepatology

authors： Yoshida T,Harada T,Shigemitsu T,Takeo Y,Miyazaki S,Okita K

更新日期：1999-07-01 00:00:00

abstract：BACKGROUND AND AIM:Liver stiffness measurement (LSM) with transient elastography is a non-invasive and reliable test for liver fibrosis. However a small proportion of patients may have unreliable LSM or LSM failure. The aim of the present study was to investigate the factors associated with unreliable LSM or LSM failur...

journal_title：Journal of gastroenterology and hepatology

authors： Wong GL,Wong VW,Chim AM,Yiu KK,Chu SH,Li MK,Chan HL

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:Frequent viral breakthroughs limit the usefulness of lamivudine in the treatment of chronic hepatitis B (CHB). The purpose of the present study was to evaluate the effects of precore stop codon mutation (G to A mutation at nucleotide 1896; A(1896)) of hepatitis B virus (HBV) on the occurrence of viral breakt...

journal_title：Journal of gastroenterology and hepatology

authors： Shin JW,Chung YH,Choi MH,Kim JA,Ryu SH,Jang MK,Kim IS,Park NH,Lee HC,Lee YS,Suh DJ

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND AND AIM:The number of colonoscopies required to reach satisfactory adenoma detection rate (ADR) is not well established. The aim of this study was to identify the appropriate number of procedures required to attain satisfactory ADR for those well-trained endoscopists who have a cecal intubation rate (CIR) ≥ ...

journal_title：Journal of gastroenterology and hepatology

authors： Dong Z,Sun H,Li B,Zhang Q,Sun K,Wang Z,Qian X,Wang J,Zhan T,Jiang Y,Chen Y,Xu S

更新日期：2020-10-26 00:00:00

abstract：BACKGROUND AND AIM:We have previously found high incidence of inflammatory bowel disease (IBD) in Australia. A population-based registry was established to assess disease severity, frequency of complications, and prognostic factors. METHODS:Incident cases were prospectively identified over 4 years. Early disease sever...

journal_title：Journal of gastroenterology and hepatology

authors： Niewiadomski O,Studd C,Hair C,Wilson J,Ding NS,Heerasing N,Ting A,McNeill J,Knight R,Santamaria J,Prewett E,Dabkowski P,Dowling D,Alexander S,Allen B,Popp B,Connell W,Desmond P,Bell S

更新日期：2015-09-01 00:00:00

abstract：:First-degree relatives of colorectal cancer patients are at increased risk for developing colorectal neoplasms. In order to assess the potentiality of colonoscopy screening in this high-risk population, 213 asymptomatic family members (age range 30-69 years, mean 42.8 years) of those patients with colorectal cancer re...

journal_title：Journal of gastroenterology and hepatology

authors： Wu CS,Tung SY,Chen PC,Kuo YC

更新日期：1995-05-01 00:00:00

abstract：:The mechanism of phagocytosis by Kupffer cells has been shown to be related to the Ca(2+)-calmodulin and the actomyosin systems. However the role of the transmembrane signal transmitter, G-protein, is still unknown. In this study, a quantitative evaluation of phagocytosis by Kupffer cells of rats in culture and the ef...

journal_title：Journal of gastroenterology and hepatology

authors： Hirose M,Watanabe S,Ueno T,Kitami N,Sato N

更新日期：1993-07-01 00:00:00

abstract：BACKGROUND AND AIM:To study the histological changes caused by transfection of the hepatocyte growth factor (HGF) gene using electroporation (EP) in a non-alcoholic steatohepatitis (NASH) cirrhotic liver model. METHODS:NASH cirrhotic livers were prepared by administering a choline-deficient diet to 5-week-old male Wis...

journal_title：Journal of gastroenterology and hepatology

authors： Kiyama S,Yamada T,Iwata H,Sekino T,Matsuo H,Yoshida N,Miyahara T,Umeda Y,Matsuno Y,Kimura M,Matsumoto K,Nakamura T,Takemura H

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND AND AIM:We previously reported that hypothermic machine perfusion (HMP) for liver preservation is feasible, but hepatic microcirculatory dysfunction and significant liver damage remain major obstacles in its application when the preservation is extended to 24 h. The underlying injury mechanism is not well un...

journal_title：Journal of gastroenterology and hepatology

authors： Xu H,Lee CY,Clemens MG,Zhang JX

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND AND AIM:Chronic inflammation is a major contributor to the initiation and progression of cancers. Lactobacillus helveticus NS8, which was originally separated from fermented koumiss, exhibited anti-inflammatory functions in our prior studies. In this study, NS8 was investigated for its potential to prevent c...

journal_title：Journal of gastroenterology and hepatology

authors： Rong J,Liu S,Hu C,Liu C

更新日期：2019-07-01 00:00:00

abstract：:There is an increasing burden in digestive cancer in the coming years. With the advancement of endoscopic therapy, new molecular target therapy and minimally invasive ablation therapy, the treatment of digestive cancer will become more complicated. In Asia where gastric cancer and hepatocellular carcinoma are still pr...

journal_title：Journal of gastroenterology and hepatology

authors： Sung J

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND AND AIMS:To evaluate and compare laparoscopic splenectomy and partial splenic embolization as supportive intervention for cirrhotic patients with hypersplenism to overcome peripheral cytopenia before the initiation of and during interferon therapy or anticancer therapy for hepatocellular carcinoma. METHODS:...

journal_title：Journal of gastroenterology and hepatology

authors： Tomikawa M,Akahoshi T,Sugimachi K,Ikeda Y,Yoshida K,Tanabe Y,Kawanaka H,Takenaka K,Hashizume M,Maehara Y

更新日期：2010-02-01 00:00:00

abstract：:Alcoholic liver disease (ALD) remains a leading cause of death in the USA. Defining mechanisms for liver cell death in ALD in order to develop potential new agents for therapeutic intervention is a major focus of the authors' work. Abnormal cytokine metabolism is a major feature of ALD, and a thorough understanding of...

journal_title：Journal of gastroenterology and hepatology

authors： Barve S,Joshi-Barve S,Song Z,Hill D,Hote P,Deaciuc I,McClain C

更新日期：2006-10-01 00:00:00