Abstract:
OBJECTIVES:We modeled triple trajectories of tobacco, alcohol, and marijuana use from adolescence to adulthood as predictors of antisocial personality disorder (ASPD) and generalized anxiety disorder (GAD). METHODS:We assessed urban African American and Puerto Rican participants (n = 816) in the Harlem Longitudinal Development Study, a psychosocial investigation, at 4 time waves (mean ages = 19, 24, 29, and 32 years). We used Mplus to obtain the 3 variable trajectories of tobacco, alcohol, and marijuana use from time 2 to time 5 and then conducted logistic regression analyses. RESULTS:A 5-trajectory group model, ranging from the use of all 3 substances (23%) to a nonuse group (9%), best fit the data. Membership in the trajectory group that used all 3 substances was associated with an increased likelihood of both ASPD (adjusted odds ratio [AOR] = 6.83; 95% CI = 1.14, 40.74; P < .05) and GAD (AOR = 4.35; 95% CI = 1.63, 11.63; P < .001) in adulthood, as compared with the nonuse group, with control for earlier proxies of these conditions. CONCLUSIONS:Adults with comorbid tobacco, alcohol, and marijuana use should be evaluated for use of other substances and for ASPD, GAD, and other psychiatric disorders. Treatment programs should address the use of all 3 substances to decrease the likelihood of comorbid psychopathology.
journal_name
Am J Public Healthjournal_title
American journal of public healthauthors
Brook JS,Lee JY,Rubenstone E,Brook DW,Finch SJdoi
10.2105/AJPH.2014.301880subject
Has Abstractpub_date
2014-08-01 00:00:00pages
1413-20issue
8eissn
0090-0036issn
1541-0048journal_volume
104pub_type
杂志文章abstract::In 1974 and 1975, a selective tuberculosis screening program was conducted in a small mining community in Ottawa County, Oklahoma. Former miners, 50 years of age and over, who had abnormal chest radiographs consistent with silicosis or inactive tuberculosis and positive tuberculin skin tests, were offered isoniazid pr...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/ajph.72.12.1404
更新日期:1982-12-01 00:00:00
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journal_title:American journal of public health
pub_type: 历史文章,杂志文章
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journal_title:American journal of public health
pub_type: 杂志文章
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journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/AJPH.2004.047779
更新日期:2005-03-01 00:00:00
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journal_title:American journal of public health
pub_type: 杂志文章,多中心研究
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更新日期:2007-08-01 00:00:00
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journal_title:American journal of public health
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更新日期:1997-05-01 00:00:00
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journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/AJPH.2014.302012
更新日期:2014-08-01 00:00:00
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pub_type: 历史文章,杂志文章
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更新日期:2000-02-01 00:00:00
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doi:10.2105/AJPH.2008.149906
更新日期:2009-11-01 00:00:00
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journal_title:American journal of public health
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doi:10.2105/AJPH.2012.300670
更新日期:2012-12-01 00:00:00
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journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/AJPH.2016.303270
更新日期:2016-10-01 00:00:00
abstract::The relationship between corneal arcus (arcus senilis) and mortality from coronary heart disease (CHD) and cardiovascular disease (CVD) is examined in a prospective study of White men (n = 3,930) and women non-hormone users (n = 2,139), ages 30-69, followed for an average of 8.4 years as part of the Lipid Research Cli...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/ajph.80.10.1200
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journal_title:American journal of public health
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更新日期:1999-05-01 00:00:00
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journal_title:American journal of public health
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pub_type: 杂志文章,多中心研究
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更新日期:2001-01-01 00:00:00
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journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/ajph.81.12.1630
更新日期:1991-12-01 00:00:00
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更新日期:2004-04-01 00:00:00
abstract::We analyzed the variation in the risk of AIDS in US Blacks, Hispanics, and other racial/ethnic groups relative to that in Whites (non-Hispanic) by geographic area and mode of acquiring HIV infection, based on data reported between June 1, 1981 and January 18, 1988 to the Centers for Disease Control and 1980 US census ...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/ajph.78.12.1539
更新日期:1988-12-01 00:00:00