Abstract:
:Fusarium is an emerging human opportunistic pathogen of growing importance, especially among immunosuppressed haematology patients due to an increased incidence of disseminated infections over the past two decades. This trend is expected only to continue due to the advances in medical and surgical technologies that will prolong the lives of the severely ill, making these patients susceptible to rare opportunistic infections. Production of mycotoxins, enzymes such as proteases, angio-invasive property and an intrinsically resistant nature, makes this genus very difficult to treat. Fusarium is frequently isolated from the cornea and less commonly from nail, skin, blood, tissue, Continuous Ambulatory Peritoneal Dialysis (CAPD) fluid, urine and pleural fluid. Conventional microscopy establishes the genus, but accurate speciation requires multilocus sequence typing with housekeeping genes such as internal transcribed spacer, translation elongation factor-1α and RPB1 and 2 (largest and second largest subunits of RNA polymerase), for which expansive internet databases exist. Identifying pathogenic species is of epidemiological significance, and the treatment includes immune reconstitution by granulocyte-colony-stimulating factor, granulocyte macrophage-colony-stimulating factor and a combination of the most active species - specific antifungals, typically liposomal amphotericin-B and voriconazole. However, patient outcome is difficult to predict even with in vitro susceptibility with these drugs. Therefore, prevention methods and antifungal prophylaxis have to be taken seriously for these vulnerable patients by vigilant healthcare workers. The current available literature on PubMed and Google Scholar using search terms 'Fusarium', 'opportunistic invasive fungi' and 'invasive fusariosis' was summarised for this review.
journal_name
Indian J Med Microbioljournal_title
Indian journal of medical microbiologyauthors
Tupaki-Sreepurna A,Kindo AJdoi
10.4103/ijmm.IJMM_16_24subject
Has Abstractpub_date
2018-01-01 00:00:00pages
8-17issue
1eissn
0255-0857issn
1998-3646pii
IndianJMedMicrobiol_2018_36_1_8_231655journal_volume
36pub_type
杂志文章,评审abstract:Purpose:Helicobacter pylori causes various gastro-intestinal diseases. Antibiotic resistance to commonly used antibiotics for the treatment of H. pylori infection is the major cause for treatment failure. The aim of this study is to determine the antimicrobial susceptibility pattern for clarithromycin and levofloxacin ...
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pub_type: 杂志文章
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abstract:PURPOSE:Various antifungal agents both topical and systemic have been introduced into clinical practice for effectively treating dermatophytic conditions. Dermatophytosis is the infection of keratinised tissues caused by fungal species of genera Trichophyton, Epidermophyton and Microsporum, commonly known as dermatophy...
journal_title:Indian journal of medical microbiology
pub_type: 杂志文章
doi:10.4103/0255-0857.167341
更新日期:2015-10-01 00:00:00
abstract::Disseminated cases of histoplasmosis in acquired immune deficiency syndrome (AIDS) are rarely reported from India. Most of these cases report isolation of this fungus from the bone marrow, lymph node aspirate, spleenic aspirate, and biopsies. We report isolation of Histoplasma capsulatum from the blood of an AIDS pati...
journal_title:Indian journal of medical microbiology
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doi:10.4103/0255-0857.81792
更新日期:2011-04-01 00:00:00
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journal_title:Indian journal of medical microbiology
pub_type: 杂志文章,评审
doi:10.4103/0255-0857.124286
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journal_title:Indian journal of medical microbiology
pub_type: 杂志文章
doi:10.4103/0255-0857.148400
更新日期:2015-01-01 00:00:00
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journal_title:Indian journal of medical microbiology
pub_type: 杂志文章
doi:10.4103/0255-0857.34774
更新日期:2007-07-01 00:00:00
abstract::Five patients with HIV associated cutaneous cryptococcal infection are reported. ...
journal_title:Indian journal of medical microbiology
pub_type: 杂志文章
doi:
更新日期:2002-07-01 00:00:00
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journal_title:Indian journal of medical microbiology
pub_type: 杂志文章
doi:
更新日期:2002-01-01 00:00:00
abstract:PURPOSE:Opportunistic viral infections cause increased morbidity and mortality among human immunodeficiency virus (HIV) infected individuals, especially those who are not on antiretroviral treatment. Early diagnosis of these opportunistic viruses will be able to reduce the risk of disease progression with appropriate i...
journal_title:Indian journal of medical microbiology
pub_type: 杂志文章
doi:10.4103/0255-0857.53202
更新日期:2009-07-01 00:00:00
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journal_title:Indian journal of medical microbiology
pub_type: 杂志文章
doi:10.4103/ijmm.IJMM_17_136
更新日期:2018-01-01 00:00:00
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journal_title:Indian journal of medical microbiology
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doi:
更新日期:2001-04-01 00:00:00
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journal_title:Indian journal of medical microbiology
pub_type: 杂志文章
doi:10.4103/ijmm.IJMM_20_136
更新日期:2020-07-01 00:00:00
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journal_title:Indian journal of medical microbiology
pub_type: 杂志文章
doi:10.4103/0255-0857.62491
更新日期:2010-04-01 00:00:00
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journal_title:Indian journal of medical microbiology
pub_type: 杂志文章
doi:10.4103/0255-0857.124308
更新日期:2014-01-01 00:00:00
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journal_title:Indian journal of medical microbiology
pub_type: 杂志文章
doi:10.4103/ijmm.IJMM_18_82
更新日期:2018-10-01 00:00:00
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journal_title:Indian journal of medical microbiology
pub_type: 杂志文章
doi:10.4103/0255-0857.154853
更新日期:2015-04-01 00:00:00
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journal_title:Indian journal of medical microbiology
pub_type: 杂志文章
doi:10.4103/0255-0857.38870
更新日期:2008-01-01 00:00:00
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journal_title:Indian journal of medical microbiology
pub_type: 杂志文章
doi:
更新日期:2003-07-01 00:00:00
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journal_title:Indian journal of medical microbiology
pub_type: 杂志文章
doi:10.4103/0255-0857.158576
更新日期:2015-07-01 00:00:00
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journal_title:Indian journal of medical microbiology
pub_type: 杂志文章
doi:
更新日期:2003-04-01 00:00:00
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journal_title:Indian journal of medical microbiology
pub_type: 杂志文章
doi:
更新日期:2004-04-01 00:00:00
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journal_title:Indian journal of medical microbiology
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更新日期:2016-04-01 00:00:00
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journal_title:Indian journal of medical microbiology
pub_type: 杂志文章
doi:10.4103/0255-0857.195353
更新日期:2016-10-01 00:00:00
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journal_title:Indian journal of medical microbiology
pub_type:
doi:10.4103/ijmm.IJMM_20_257
更新日期:2020-07-01 00:00:00
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journal_title:Indian journal of medical microbiology
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doi:
更新日期:2001-10-01 00:00:00
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journal_title:Indian journal of medical microbiology
pub_type: 杂志文章
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更新日期:2019-07-01 00:00:00
abstract:PURPOSE:Malassezia yeasts are globally distributed agents of pityriasis versicolor and are implicated in the pathogenesis of seborrhoeic and atopic dermatitis. The aim of this study is to identify the Malassezia species obtained from pityriasis versicolor patients, using morphological, biochemical, physiological as wel...
journal_title:Indian journal of medical microbiology
pub_type: 杂志文章
doi:10.4103/0255-0857.55445
更新日期:2009-10-01 00:00:00
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journal_title:Indian journal of medical microbiology
pub_type: 杂志文章
doi:10.4103/0255-0857.37354
更新日期:2007-10-01 00:00:00
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journal_title:Indian journal of medical microbiology
pub_type: 杂志文章
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更新日期:2008-10-01 00:00:00
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journal_title:Indian journal of medical microbiology
pub_type: 杂志文章
doi:10.4103/0255-0857.43578
更新日期:2008-10-01 00:00:00