Mechanical signaling in plant morphogenesis.

Abstract:

:To control changes in shape during development, the molecular regulatory networks have to interact with the mechanical, structural components of the individual cells, in particular the cytoskeleton and the cell wall. A widely accepted hypothesis proposes that molecular regulation interferes with wall synthesis and stiffness, causing the wall polymers to yield to the internal turgor pressure. However, growth is not only the result of a rigid molecular program instructing the cells precisely what to do. Local differences in growth rates between neighboring cells generate mechanical constraints that can feed back on the regulatory networks and the cytoskeleton. A number of components involved in the perception of these constraints have been identified, although their precise function remains to be determined.

journal_name

Curr Opin Genet Dev

authors

Zhao F,Chen W,Traas J

doi

10.1016/j.gde.2018.04.001

subject

Has Abstract

pub_date

2018-08-01 00:00:00

pages

26-30

eissn

0959-437X

issn

1879-0380

pii

S0959-437X(18)30034-0

journal_volume

51

pub_type

杂志文章,评审
  • Comparative genomics of malaria parasites.

    abstract::In the past few years, the area of comparative genomics of malaria parasites has begun to come of age, with the completion of genome sequencing projects of four Plasmodium species, and several functional genomics studies. A picture is emerging of a parasite genome that is highly adapted to its mammalian and vector hos...

    journal_title:Current opinion in genetics & development

    pub_type: 杂志文章,评审

    doi:10.1016/j.gde.2005.09.001

    authors: Hall N,Carlton J

    更新日期:2005-12-01 00:00:00

  • Nuclear neighborhoods and gene expression.

    abstract::The eukaryotic nucleus is a highly compartmentalized and dynamic environment. Chromosome territories are arranged nonrandomly within the nucleus and numerous studies have indicated that a gene's position in the nucleus can impact its transcriptional activity. Here, we focus on recent advances in our understanding of t...

    journal_title:Current opinion in genetics & development

    pub_type: 杂志文章,评审

    doi:10.1016/j.gde.2009.02.007

    authors: Zhao R,Bodnar MS,Spector DL

    更新日期:2009-04-01 00:00:00

  • Common predisposition alleles for moderately common cancers: bladder cancer.

    abstract::Bladder cancer is the 5th commonest cancer and two major risk factors are smoking and occupational chemical exposure. There is also evidence of a genetic component to its aetiology. Candidate gene studies have mostly focused on genes involved in adduct metabolism and DNA repair, including a recent consortium-based met...

    journal_title:Current opinion in genetics & development

    pub_type: 杂志文章,评审

    doi:10.1016/j.gde.2010.01.002

    authors: Kiltie AE

    更新日期:2010-06-01 00:00:00

  • Genetics of Alzheimer's disease: new evidences for an old hypothesis?

    abstract::Alzheimer's disease (AD) is the prime cause of dementia and presents a strong genetic predisposition (60-80% of the attributable risk). In addition to APOE, a major recognized genetic determinant of AD, systematic, high-throughput genomic approaches have recently allowed the characterization of four new genetic determ...

    journal_title:Current opinion in genetics & development

    pub_type: 杂志文章,评审

    doi:10.1016/j.gde.2011.02.002

    authors: Lambert JC,Amouyel P

    更新日期:2011-06-01 00:00:00

  • Constructive antagonism in limb development.

    abstract::Several advances have been made in our understanding of the control of the growth and patterning of embryonic limbs. Development of the vertebrate limb is dependent on reciprocal interactions between the ectoderm and mesoderm that regulate the structure and function of the apical ectodermal ridge. One key component of...

    journal_title:Current opinion in genetics & development

    pub_type: 杂志文章

    doi:10.1016/s0959-437x(00)00101-5

    authors: Dudley AT,Tabin CJ

    更新日期:2000-08-01 00:00:00

  • RNA-binding proteins as regulators of gene expression.

    abstract::A plethora of post-transcriptional mechanisms are involved in essential steps in the pathway of genetic information expression in eukaryotes. These processes are specified by cis-acting signals on RNAs and are mediated by specific trans-acting factors, including RNA-binding proteins and small complementary RNAs. Recen...

    journal_title:Current opinion in genetics & development

    pub_type: 杂志文章,评审

    doi:10.1016/s0959-437x(97)80148-7

    authors: Siomi H,Dreyfuss G

    更新日期:1997-06-01 00:00:00

  • miSSING LINKS: miRNAs and plant development.

    abstract::The discovery of hundreds of plant micro RNAs (miRNAs) has triggered much speculation about their potential roles in plant development. The search for plant genes involved in miRNA processing has revealed common factors such as DICER, and new molecules, including HEN1. Progress is also being made toward identifying mi...

    journal_title:Current opinion in genetics & development

    pub_type: 杂志文章,评审

    doi:10.1016/s0959-437x(03)00081-9

    authors: Hunter C,Poethig RS

    更新日期:2003-08-01 00:00:00

  • Crop evolution: from genetics to genomics.

    abstract::The advent of the genomics age has greatly facilitated the study of crop evolution. While full-scale genome sequencing projects are underway for just a handful of crop plants, recent years have witnessed a tremendous increase in the availability of DNA sequence data for virtually all major crops. Such resources have b...

    journal_title:Current opinion in genetics & development

    pub_type: 杂志文章,评审

    doi:10.1016/j.gde.2007.09.003

    authors: Burke JM,Burger JC,Chapman MA

    更新日期:2007-12-01 00:00:00

  • Chromatin organization: form to function.

    abstract::Recent developments in technology have made it possible to create high resolution genome-wide maps of histone marks, DNA binding proteins and physical interactions along genomic regions. Chromatin features are found together in different combinations, dividing the genome up into domains with distinct functional proper...

    journal_title:Current opinion in genetics & development

    pub_type: 杂志文章,评审

    doi:10.1016/j.gde.2012.11.011

    authors: de Graaf CA,van Steensel B

    更新日期:2013-04-01 00:00:00

  • The mouse alpha-globin cluster: a paradigm for studying genome regulation and organization.

    abstract::The mammalian globin gene clusters provide a paradigm for studying the relationship between genome structure and function. As blood stem cells undergo lineage specification and differentiation to form red blood cells, the chromatin structure and expression of the α-globin cluster change. The gradual activation of the ...

    journal_title:Current opinion in genetics & development

    pub_type: 杂志文章,评审

    doi:10.1016/j.gde.2020.10.003

    authors: Oudelaar AM,Beagrie RA,Kassouf MT,Higgs DR

    更新日期:2020-11-19 00:00:00

  • Mapping the journey from totipotency to lineage specification in the mouse embryo.

    abstract::Understanding the past is to understand the present. Mammalian life, with all its complexity comes from a humble beginning of a single fertilized egg cell. Achieving this requires an enormous diversification of cellular function, the majority of which is generated through a series of cellular decisions during embryoge...

    journal_title:Current opinion in genetics & development

    pub_type: 杂志文章,评审

    doi:10.1016/j.gde.2015.08.002

    authors: Leung CY,Zernicka-Goetz M

    更新日期:2015-10-01 00:00:00

  • Multipotentiality of the neural crest.

    abstract::Multiple neural and non-neural cell types arise from the neural crest (NC) in vertebrate embryos. Recent work has provided evidence for multipotent stem cells and intermediate precursors in the early NC cell population as well as in various NC derivatives in embryos and even in adult. Advances have been made towards u...

    journal_title:Current opinion in genetics & development

    pub_type: 杂志文章,评审

    doi:10.1016/j.gde.2003.08.002

    authors: Le Douarin NM,Dupin E

    更新日期:2003-10-01 00:00:00

  • microRNAs in neurons: manifold regulatory roles at the synapse.

    abstract::The regulation of synapse formation and plasticity in the developing and adult brain underlies a complex interplay of intrinsic genetic programs and extrinsic factors. Recent research identified microRNAs (miRNAs), a class of small non-coding RNAs, as a new functional layer in this regulatory network. Within only a fe...

    journal_title:Current opinion in genetics & development

    pub_type: 杂志文章,评审

    doi:10.1016/j.gde.2011.04.008

    authors: Siegel G,Saba R,Schratt G

    更新日期:2011-08-01 00:00:00

  • Baculoviruses: high-level expression in insect cells.

    abstract::Baculoviruses continue to serve as workhorse vectors for the high-level expression of eukaryotic genes in insect cells; however, numerous researchers are also finding novel uses for these vectors by taking advantage of the unique nature of the viruses and their host cells. Concurrently, the technology involved in cons...

    journal_title:Current opinion in genetics & development

    pub_type: 杂志文章,评审

    doi:10.1016/s0959-437x(05)80348-x

    authors: Miller LK

    更新日期:1993-02-01 00:00:00

  • Retina regeneration in zebrafish.

    abstract::Unlike mammals, zebrafish are able to regenerate a damaged retina. Key to this regenerative response are Müller glia that respond to retinal injury by undergoing a reprogramming event that allows them to divide and generate a retinal progenitor that is multipotent and responsible for regenerating all major retinal neu...

    journal_title:Current opinion in genetics & development

    pub_type: 杂志文章,评审

    doi:10.1016/j.gde.2016.05.009

    authors: Wan J,Goldman D

    更新日期:2016-10-01 00:00:00

  • Message in a nucleus: signaling to the transcriptional machinery.

    abstract::Tissue differentiation and signal transduction involve dramatic changes in gene expression. These changes can be brought about by the expression or activation of sequence-specific transcription factors. In order to regulate their target genes, such factors must navigate the intricate chromatin environment and engage t...

    journal_title:Current opinion in genetics & development

    pub_type: 杂志文章,评审

    doi:10.1016/j.gde.2008.07.007

    authors: Carrera I,Treisman JE

    更新日期:2008-10-01 00:00:00

  • The structure-function link of compensated chromatin in Drosophila.

    abstract::All the aspects of transcription are controlled by complexes that modify or remodel chromatin at the level of individual genes, gene clusters, or whole chromosomes. The MSL complex that is responsible for dosage compensation in Drosophila is an example of complexes that operate at the whole-chromosome level on the tra...

    journal_title:Current opinion in genetics & development

    pub_type: 杂志文章,评审

    doi:10.1016/j.gde.2009.10.004

    authors: Lucchesi JC

    更新日期:2009-12-01 00:00:00

  • Establishing myogenic identity during somitogenesis.

    abstract::Over the past year, interest has focused on identifying signalling molecules--including Wnts, Sonic hedgehog, BMP-4, and noggin--that divert somitic mesodermal cells into the muscle lineage, either by induction or derepression. New mouse mutants have also provided insights into somite formation and differentiation, as...

    journal_title:Current opinion in genetics & development

    pub_type: 杂志文章,评审

    doi:10.1016/s0959-437x(97)80011-1

    authors: Tajbakhsh S,Cossu G

    更新日期:1997-10-01 00:00:00

  • Lessons on immune tolerance from the monogenic disease APS1.

    abstract::Autoimmunity is a complex disease process that results from a breakdown in the ability of the immune system to discriminate self from non-self. One approach to unraveling how autoimmunity occurs is to study monogenic diseases, for which a single gene defect is responsible. Recent work on the monogenic autoimmune disea...

    journal_title:Current opinion in genetics & development

    pub_type: 杂志文章,评审

    doi:10.1016/j.gde.2007.04.001

    authors: DeVoss JJ,Anderson MS

    更新日期:2007-06-01 00:00:00

  • Papillomaviruses and human oncogenesis.

    abstract::During the past year, significant advances have been made in understanding the functions of the oncoproteins, E6 and E7, of human papillomaviruses that are associated with malignant genital tumors. In addition, important new information is now available on the responses of both the keratinocyte and of the individual f...

    journal_title:Current opinion in genetics & development

    pub_type: 杂志文章,评审

    doi:10.1016/s0959-437x(05)80329-6

    authors: Gissmann L

    更新日期:1992-02-01 00:00:00

  • The fight of viruses against apoptosis.

    abstract::The induction of apoptosis of virus-infected cells is an important host defense mechanism against invading pathogens. Some viruses express anti-apoptotic proteins that efficiently block apoptosis induced by death receptors or in response to stress signaled through mitochondria. Viral interference with host cell apopto...

    journal_title:Current opinion in genetics & development

    pub_type: 杂志文章,评审

    doi:10.1016/s0959-437x(98)80066-x

    authors: Tschopp J,Thome M,Hofmann K,Meinl E

    更新日期:1998-02-01 00:00:00

  • Regulation of p21ras by GTPase activating proteins and guanine nucleotide exchange proteins.

    abstract::Ras proteins play a critical role in controlling normal cellular growth and, when activated by mutation, in causing malignant transformation. Regulation of p21ras is achieved by GTPase activating proteins, which control the rate of hydrolysis of GTP to GDP, and also by GDP dissociation stimulators, which catalyze the ...

    journal_title:Current opinion in genetics & development

    pub_type: 杂志文章,评审

    doi:10.1016/s0959-437x(05)80315-6

    authors: Downward J

    更新日期:1992-02-01 00:00:00

  • The role of Wnt genes in vertebrate development.

    abstract::Over the past decade, many potential candidates for molecules involved in pattern formation in the vertebrate embryo have been identified. Manipulation of the expression of some of these factors has generated fascinating results that have allowed investigators to address their roles in embryogenesis. One such family c...

    journal_title:Current opinion in genetics & development

    pub_type: 杂志文章,评审

    doi:10.1016/s0959-437x(05)80172-8

    authors: Dickinson ME,McMahon AP

    更新日期:1992-08-01 00:00:00

  • Epigenetic variation and inheritance in mammals.

    abstract::What determines phenotype is one of the most fundamental questions in biology. Historically, the search for answers had focused on genetic or environmental variants, but recent studies in epigenetics have revealed a third mechanism that can influence phenotypic outcomes, even in the absence of genetic or environmental...

    journal_title:Current opinion in genetics & development

    pub_type: 杂志文章,评审

    doi:10.1016/j.gde.2006.09.002

    authors: Rakyan VK,Beck S

    更新日期:2006-12-01 00:00:00

  • Ctrl-Alt-inDel: genome editing to reprogram a cell in the clinic.

    abstract::Genome editing with engineered nucleases (zinc finger, TAL effector, or CRISPR/Cas9-based) enables `write' access to regulatory programs executed by primary human cells. A decade of its clinical development, along with a reduction of conventional gene therapy to medical and commercial practice, has made cell reprogram...

    journal_title:Current opinion in genetics & development

    pub_type: 杂志文章,评审

    doi:10.1016/j.gde.2018.05.005

    authors: Urnov FD

    更新日期:2018-10-01 00:00:00

  • Mechanotransduction in cardiovascular morphogenesis and tissue engineering.

    abstract::Cardiovascular morphogenesis involves cell behavior and cell identity changes that are activated by mechanical forces associated with heart function. Recently, advances in in vivo imaging, methods to alter blood flow, and computational modelling have greatly advanced our understanding of how forces produced by heart c...

    journal_title:Current opinion in genetics & development

    pub_type: 杂志文章,评审

    doi:10.1016/j.gde.2019.08.002

    authors: Duchemin AL,Vignes H,Vermot J,Chow R

    更新日期:2019-08-01 00:00:00

  • Investigating the principles of morphogen gradient formation: from tissues to cells.

    abstract::Morphogen gradients regulate the patterning and growth of many tissues, hence a key question is how they are established and maintained during development. Theoretical descriptions have helped to explain how gradient shape is controlled by the rates of morphogen production, spreading and degradation. These effective r...

    journal_title:Current opinion in genetics & development

    pub_type: 杂志文章,评审

    doi:10.1016/j.gde.2012.08.004

    authors: Kicheva A,Bollenbach T,Wartlick O,Jülicher F,Gonzalez-Gaitan M

    更新日期:2012-12-01 00:00:00

  • Facts about FACT and transcript elongation through chromatin.

    abstract::The regulation of transcription elongation within the context of chromatin is a topic of great interest. Even though chromatin presents a barrier to transcription by the PolII machinery in vitro, this process is rather efficient in vivo. Importantly, the chromatin structure of the actively transcribed genes is altered...

    journal_title:Current opinion in genetics & development

    pub_type: 杂志文章,评审

    doi:10.1016/j.gde.2004.02.004

    authors: Belotserkovskaya R,Reinberg D

    更新日期:2004-04-01 00:00:00

  • Recent advances in understanding chromatin remodeling by Swi/Snf complexes.

    abstract::Members of the Swi/Snf family of chromatin-remodeling complexes play critical roles in transcriptional control. Recent studies have made significant advances in our understanding of the fundamental aspects of Swi/Snf complexes, including the roles of specific subunits, the repression of transcription, and the mechanis...

    journal_title:Current opinion in genetics & development

    pub_type: 杂志文章,评审

    doi:10.1016/s0959-437x(03)00022-4

    authors: Martens JA,Winston F

    更新日期:2003-04-01 00:00:00

  • Molecular genetics of tooth development.

    abstract::Organogenesis depends upon a well-ordered series of inductive events involving coordination of molecular pathways that regulate the generation and patterning of specific cell types. Key questions in organogenesis involve the identification of the molecular mechanisms by which proteins interact to organize distinct pat...

    journal_title:Current opinion in genetics & development

    pub_type: 杂志文章,评审

    doi:10.1016/j.gde.2009.09.002

    authors: Bei M

    更新日期:2009-10-01 00:00:00