Bifacial stem cell niches in fish and plants.

Abstract:

:Embryonic development is key for determining the architecture and shape of multicellular bodies. However, most cells are produced postembryonically in, at least partly, differentiated organs. In this regard, organismal growth faces common challenges in coordinating expansion and function of body structures. Here we compare two examples for postembryonic growth processes from two different kingdoms of life to reveal common regulatory principles: lateral growth of plants and the enlargement of the fish retina. In both cases, growth is based on stem cell systems mediating radial growth by a bifacial mode of tissue production. Surprisingly, although being evolutionary distinct, we find similar patterns in regulatory circuits suggesting the existence of preferable solutions to a common developmental problem.

journal_name

Curr Opin Genet Dev

authors

Shi D,Tavhelidse T,Thumberger T,Wittbrodt J,Greb T

doi

10.1016/j.gde.2017.02.002

subject

Has Abstract

pub_date

2017-08-01 00:00:00

pages

28-33

eissn

0959-437X

issn

1879-0380

pii

S0959-437X(16)30134-4

journal_volume

45

pub_type

杂志文章,评审
  • Cdks and the Drosophila cell cycle.

    abstract::Cyclin-dependent kinases play essential roles in driving the cell cycle. Much progress has been made in Drosophila over the past year in identifying the specific requirements for individual cyclins in particular cell cycle events. These studies encompass many aspects of the cell cycle, from the addition of a G1 phase ...

    journal_title:Current opinion in genetics & development

    pub_type: 杂志文章,评审

    doi:10.1016/s0959-437x(97)80104-9

    authors: Follette PJ,O'Farrell PH

    更新日期:1997-02-01 00:00:00

  • Mapping the journey from totipotency to lineage specification in the mouse embryo.

    abstract::Understanding the past is to understand the present. Mammalian life, with all its complexity comes from a humble beginning of a single fertilized egg cell. Achieving this requires an enormous diversification of cellular function, the majority of which is generated through a series of cellular decisions during embryoge...

    journal_title:Current opinion in genetics & development

    pub_type: 杂志文章,评审

    doi:10.1016/j.gde.2015.08.002

    authors: Leung CY,Zernicka-Goetz M

    更新日期:2015-10-01 00:00:00

  • Small molecule-induced cellular fate reprogramming: promising road leading to Rome.

    abstract::Cellular fate reprogramming holds great promise to generate functional cell types for replenishing new cells and restoring functional loss. Inspired by transcription factor-induced reprogramming, the field of cellular reprogramming has greatly advanced and developed into divergent streams of reprogramming approaches. ...

    journal_title:Current opinion in genetics & development

    pub_type: 杂志文章,评审

    doi:10.1016/j.gde.2018.05.004

    authors: Li X,Xu J,Deng H

    更新日期:2018-10-01 00:00:00

  • The role of yeast artificial chromosome clones in generating genome maps.

    abstract::The cloning of large DNAs as yeast artificial chromosomes (YACs) holds the promise of greatly expanding the scope of physical genomic mapping. Recent improvements in YAC clone libraries and their screening, as well as in the analysis of YAC-cloned DNA, are beginning to fulfill the potential of this system. ...

    journal_title:Current opinion in genetics & development

    pub_type: 杂志文章,评审

    doi:10.1016/0959-437x(91)80044-m

    authors: Burke DT

    更新日期:1991-06-01 00:00:00

  • Spatial aspects of intracellular information processing.

    abstract::The computational properties of intracellular biochemical networks, for which the cell is assumed to be a 'well-mixed' reactor, have already been widely characterized. What has so far not received systematic treatment is the important role of space in many intracellular computations. Spatial network computations can b...

    journal_title:Current opinion in genetics & development

    pub_type: 杂志文章,评审

    doi:10.1016/j.gde.2009.12.006

    authors: Kinkhabwala A,Bastiaens PI

    更新日期:2010-02-01 00:00:00

  • Transcription and DNA supercoiling.

    abstract::Transcription and supercoiling of the DNA template are interrelated. This review summarizes recent progress in the study of how template topology affects transcription, and how transcription affects template topology inside wild-type and DNA topoisomerase mutant cells. The interplay between DNA supercoiling and transc...

    journal_title:Current opinion in genetics & development

    pub_type: 杂志文章,评审

    doi:10.1016/s0959-437x(05)80096-6

    authors: Wang JC,Lynch AS

    更新日期:1993-10-01 00:00:00

  • The molecular origins of multicellular transitions.

    abstract::Multicellularity has evolved multiple times independently from a variety of ancestral unicellular lineages. Past research on multicellularity was focused more on explaining why it was repeatedly invented and less so on the molecular foundations associated with each transition. Several recent comparative functional ana...

    journal_title:Current opinion in genetics & development

    pub_type: 杂志文章,评审

    doi:10.1016/j.gde.2008.09.004

    authors: Rokas A

    更新日期:2008-12-01 00:00:00

  • Congenital nephrotic syndromes.

    abstract::Many acquired and familial renal diseases in man lead to kidney dysfunction and nephrotic syndrome. These diseases share a common pathological fate in the form of glomerular dysfunction and proteinuria. Classification of the disease is difficult because the onset of pathological appearance in congenital nephrotic synd...

    journal_title:Current opinion in genetics & development

    pub_type: 杂志文章,评审

    doi:10.1016/s0959-437x(00)00197-0

    authors: Khoshnoodi J,Tryggvason K

    更新日期:2001-06-01 00:00:00

  • Utilization of genomic signatures to direct use of primary chemotherapy.

    abstract::The success of treatment of cancer patients depends on matching the most effective therapeutic regimen with the characteristics of the individual patient, balancing benefit against risk of adverse events. The primary challenge in achieving this goal is the heterogeneity of the disease, recognizing that breast, lung, c...

    journal_title:Current opinion in genetics & development

    pub_type: 杂志文章,评审

    doi:10.1016/j.gde.2008.01.018

    authors: Potti A,Nevins JR

    更新日期:2008-02-01 00:00:00

  • Functional impact of the human mobilome.

    abstract::The human genome is replete with interspersed repetitive sequences derived from the propagation of mobile DNA elements. Three families of human retrotransposons remain active today: LINE1, Alu, and SVA elements. Since 1988, de novo insertions at previously recognized disease loci have been shown to generate highly pen...

    journal_title:Current opinion in genetics & development

    pub_type: 杂志文章,评审

    doi:10.1016/j.gde.2013.02.007

    authors: Babatz TD,Burns KH

    更新日期:2013-06-01 00:00:00

  • The fight of viruses against apoptosis.

    abstract::The induction of apoptosis of virus-infected cells is an important host defense mechanism against invading pathogens. Some viruses express anti-apoptotic proteins that efficiently block apoptosis induced by death receptors or in response to stress signaled through mitochondria. Viral interference with host cell apopto...

    journal_title:Current opinion in genetics & development

    pub_type: 杂志文章,评审

    doi:10.1016/s0959-437x(98)80066-x

    authors: Tschopp J,Thome M,Hofmann K,Meinl E

    更新日期:1998-02-01 00:00:00

  • Selfish operons: the evolutionary impact of gene clustering in prokaryotes and eukaryotes.

    abstract::The Selfish Operon Model postulates that the organization of bacterial genes into operons is beneficial to the constituent genes in that proximity allows horizontal cotransfer of all genes required for a selectable phenotype; eukaryotic operons formed for very different reasons. Horizontal transfer of selfish operons ...

    journal_title:Current opinion in genetics & development

    pub_type: 杂志文章,评审

    doi:10.1016/s0959-437x(99)00025-8

    authors: Lawrence J

    更新日期:1999-12-01 00:00:00

  • Colonial ascidians as model organisms for the study of germ cells, fertility, whole body regeneration, vascular biology and aging.

    abstract::Colonial ascidians are marine invertebrate chordates that are the closest invertebrate relative to the vertebrates. Colonies of Botryllus schlosseri undergo a continuous asexual reproduction process that involves the regeneration of entire new bodies, which include all somatic and germline tissues. This adult regenera...

    journal_title:Current opinion in genetics & development

    pub_type: 杂志文章,评审

    doi:10.1016/j.gde.2016.06.001

    authors: Kassmer SH,Rodriguez D,De Tomaso AW

    更新日期:2016-08-01 00:00:00

  • Establishing myogenic identity during somitogenesis.

    abstract::Over the past year, interest has focused on identifying signalling molecules--including Wnts, Sonic hedgehog, BMP-4, and noggin--that divert somitic mesodermal cells into the muscle lineage, either by induction or derepression. New mouse mutants have also provided insights into somite formation and differentiation, as...

    journal_title:Current opinion in genetics & development

    pub_type: 杂志文章,评审

    doi:10.1016/s0959-437x(97)80011-1

    authors: Tajbakhsh S,Cossu G

    更新日期:1997-10-01 00:00:00

  • Pathophysiology and biochemistry of cardiovascular disease.

    abstract::Atherosclerosis is the major cause of cardiovascular disease. Hypercholesterolaemia, hypertension and cigarette smoking are the common risk factors for atherosclerosis. These risk factors unite behind a convergence of mechanism, involving oxidation and inflammation in the artery wall that, with time, gives rise to cha...

    journal_title:Current opinion in genetics & development

    pub_type: 杂志文章,评审

    doi:10.1016/j.gde.2004.04.012

    authors: Scott J

    更新日期:2004-06-01 00:00:00

  • The genetics of Parkinson's disease.

    abstract::The effort to map the entire human genome has led recently to the important milestone publication in late 1999 of the complete sequence of chromosome 22. This has been facilitated by increasingly sophisticated tools for genetic analysis and the ensuing wealth of detailed genetic information. The quest for genetic fact...

    journal_title:Current opinion in genetics & development

    pub_type: 杂志文章,评审

    doi:10.1016/s0959-437x(00)00082-4

    authors: de Silva HR,Khan NL,Wood NW

    更新日期:2000-06-01 00:00:00

  • Retina regeneration in zebrafish.

    abstract::Unlike mammals, zebrafish are able to regenerate a damaged retina. Key to this regenerative response are Müller glia that respond to retinal injury by undergoing a reprogramming event that allows them to divide and generate a retinal progenitor that is multipotent and responsible for regenerating all major retinal neu...

    journal_title:Current opinion in genetics & development

    pub_type: 杂志文章,评审

    doi:10.1016/j.gde.2016.05.009

    authors: Wan J,Goldman D

    更新日期:2016-10-01 00:00:00

  • Targeting multi-cellular organisms.

    abstract::For many years, biologists' efforts in achieving gene targeting by homologous recombination in multicellular organisms have been hampered by the difficulty in culturing pluripotent stem cells. Recent advances have eliminated this requirement for several animal species. For large mammals, cloning by nuclear transfer ha...

    journal_title:Current opinion in genetics & development

    pub_type: 杂志文章,评审

    doi:10.1016/s0959-437x(03)00018-2

    authors: Gong M,Rong YS

    更新日期:2003-04-01 00:00:00

  • Recent advances in understanding chromatin remodeling by Swi/Snf complexes.

    abstract::Members of the Swi/Snf family of chromatin-remodeling complexes play critical roles in transcriptional control. Recent studies have made significant advances in our understanding of the fundamental aspects of Swi/Snf complexes, including the roles of specific subunits, the repression of transcription, and the mechanis...

    journal_title:Current opinion in genetics & development

    pub_type: 杂志文章,评审

    doi:10.1016/s0959-437x(03)00022-4

    authors: Martens JA,Winston F

    更新日期:2003-04-01 00:00:00

  • Microsatellites and their application to population genetic studies.

    abstract::Microsatellites may soon become the markers of choice for molecular population genetic studies. However, our knowledge of these simple repetitive sequences and how they evolve in natural populations is far from complete. We highlight some recent results of population studies and advances in our ability to interpret so...

    journal_title:Current opinion in genetics & development

    pub_type: 杂志文章,评审

    doi:10.1016/0959-437x(93)90017-j

    authors: Bruford MW,Wayne RK

    更新日期:1993-12-01 00:00:00

  • Synthetic transcription factors for cell fate reprogramming.

    abstract::The ability to reprogram cell lineage specification through the activity of master regulatory transcription factors has transformed disease modeling, drug screening, and cell therapy for regenerative medicine. Recent advances in the engineering of synthetic transcription factors to modulate endogenous gene expression ...

    journal_title:Current opinion in genetics & development

    pub_type: 杂志文章,评审

    doi:10.1016/j.gde.2018.05.001

    authors: Black JB,Gersbach CA

    更新日期:2018-10-01 00:00:00

  • Polarity determination in the Drosophila eye.

    abstract::In the Drosophila eye, photoreceptor clusters are arranged with mirror-image symmetry about the dorso-ventral midline. Recent work indicates critical rôles for Wingless and JAK/STAT signalling in setting up long-range gradients of positional information that determine this symmetry. Furthermore, important functions ha...

    journal_title:Current opinion in genetics & development

    pub_type: 杂志文章,评审

    doi:10.1016/S0959-437X(99)80067-7

    authors: Strutt H,Strutt D

    更新日期:1999-08-01 00:00:00

  • How genetic modifiers influence the phenotype of spinal muscular atrophy and suggest future therapeutic approaches.

    abstract::Both complex disorders and monogenetic diseases are often modulated in their phenotype by further genetic, epigenetic or extrinsic factors. This gives rise to extensive phenotypic variability and potentially protection from disease manifestations, known as incomplete penetrance. Approaches including whole transcriptom...

    journal_title:Current opinion in genetics & development

    pub_type: 杂志文章,评审

    doi:10.1016/j.gde.2013.03.003

    authors: Wirth B,Garbes L,Riessland M

    更新日期:2013-06-01 00:00:00

  • Patterning the cerebral cortex: traveling with morphogens.

    abstract::The neocortex represents the brain structure that has been subjected to a major expansion in its relative size during the course of mammalian evolution. An exquisite coordination of appropriate growth of competent territories along multiple axes and their spatial patterning is required for regionalization of the corti...

    journal_title:Current opinion in genetics & development

    pub_type: 杂志文章,评审

    doi:10.1016/j.gde.2010.05.003

    authors: Borello U,Pierani A

    更新日期:2010-08-01 00:00:00

  • Spore development in Bacillus subtilis.

    abstract::Cell-cell and starvation signals are funneled through the phosphorelay to initiate sporulation by activating the transcription regulator SpoOA. Activation of SpoOA leads to synthesis of the transcription factors sigmaF and sigmaE. Substantial advances have been made in our understanding of the signal circuitry of the ...

    journal_title:Current opinion in genetics & development

    pub_type: 杂志文章,评审

    doi:10.1016/s0959-437x(96)80080-3

    authors: Piggot PJ

    更新日期:1996-10-01 00:00:00

  • Temporal dynamics, spatial range, and transcriptional interpretation of the Dorsal morphogen gradient.

    abstract::Dorsoventral pattern of Drosophila embryo is specified by the nuclear localization gradient of the transcription factor Dorsal. Genetic and genomic studies of this morphogen gradient provided important insights into spatial control of gene expression in development. Recent live imaging experiments revealed hitherto un...

    journal_title:Current opinion in genetics & development

    pub_type: 杂志文章,评审

    doi:10.1016/j.gde.2012.08.005

    authors: Rushlow CA,Shvartsman SY

    更新日期:2012-12-01 00:00:00

  • Functional genetics of early human development.

    abstract::Understanding the genetic underpinning of early human development is of great interest not only for basic developmental and stem cell biology but also for regenerative medicine, infertility treatments, and better understanding the causes of congenital disease. Our current knowledge has mainly been generated with the u...

    journal_title:Current opinion in genetics & development

    pub_type: 杂志文章,评审

    doi:10.1016/j.gde.2018.04.005

    authors: Ortega NM,Winblad N,Plaza Reyes A,Lanner F

    更新日期:2018-10-01 00:00:00

  • New insight into BRAF mutations in cancer.

    abstract::There has been much recent progress in our understanding of the role played by the RAS-RAF-MEK-ERK cascade in human cancer. RAS is an oncogene and this pathway is known to promote proliferation and malignant transformation. More recently, however, RAF has become the focus of attention, particularly in melanoma, where ...

    journal_title:Current opinion in genetics & development

    pub_type: 杂志文章,评审

    doi:10.1016/j.gde.2006.12.005

    authors: Dhomen N,Marais R

    更新日期:2007-02-01 00:00:00

  • Horizontal transfer of mitochondria between mammalian cells: beyond co-culture approaches.

    abstract::Current dogma holds that genes are the property of individual mammalian cells and partition between daughter cells during cell division. However, and rather unexpectedly, recent research has demonstrated horizontal cell-to-cell transfer of mitochondria and mitochondrial DNA in several mammalian cell culture systems. F...

    journal_title:Current opinion in genetics & development

    pub_type: 杂志文章,评审

    doi:10.1016/j.gde.2016.04.003

    authors: Berridge MV,McConnell MJ,Grasso C,Bajzikova M,Kovarova J,Neuzil J

    更新日期:2016-06-01 00:00:00

  • Rodent models of genetic disease.

    abstract::The genetic study of rats and mice using natural variants, natural mutations, chemical or radiation induced mutations, engineered mutations and conditional engineered mutations has provided the tools for investigating the genetics of disease. The completion of the mouse genomic sequence and progress towards sequencing...

    journal_title:Current opinion in genetics & development

    pub_type: 杂志文章,评审

    doi:10.1016/s0959-437x(03)00051-0

    authors: Cox RD,Brown SD

    更新日期:2003-06-01 00:00:00