Abstract:
:Embryonic development is key for determining the architecture and shape of multicellular bodies. However, most cells are produced postembryonically in, at least partly, differentiated organs. In this regard, organismal growth faces common challenges in coordinating expansion and function of body structures. Here we compare two examples for postembryonic growth processes from two different kingdoms of life to reveal common regulatory principles: lateral growth of plants and the enlargement of the fish retina. In both cases, growth is based on stem cell systems mediating radial growth by a bifacial mode of tissue production. Surprisingly, although being evolutionary distinct, we find similar patterns in regulatory circuits suggesting the existence of preferable solutions to a common developmental problem.
journal_name
Curr Opin Genet Devjournal_title
Current opinion in genetics & developmentauthors
Shi D,Tavhelidse T,Thumberger T,Wittbrodt J,Greb Tdoi
10.1016/j.gde.2017.02.002subject
Has Abstractpub_date
2017-08-01 00:00:00pages
28-33eissn
0959-437Xissn
1879-0380pii
S0959-437X(16)30134-4journal_volume
45pub_type
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