Exercise-induced bronchospasm in children and adolescents with allergic rhinitis by treadmill and hyperventilation challenges.

abstract：:The aim of our study was to evaluate the utility of interrupter resistance (R(int)), transcutaneous oximetry and auscultation as outcome measures for a recently suggested tripling-dose methacholine (Mch) challenge in pre-school children. We studied 57 children aged 3-6 years. R(int) was measured at baseline and after ...

journal_title：Respiratory medicine

authors： Kivastik J,Gibson AM,Primhak RA

更新日期：2007-12-01 00:00:00

abstract：INTRODUCTION:Objective of this study was to validate an activity monitor (DynaPort MoveMonitor [MM], McRoberts, The Hague, The Netherlands) against night-vision video analysis during sleep. METHODS:Twenty patients (65 ± 11 years old, mean body-mass-index: 27 ± 6 kg/m(2)) with different chronic lung diseases were recru...

journal_title：Respiratory medicine

authors： Gloeckl R,Damisch T,Prinzen J,van Lummel R,Pengel E,Schoenheit-Kenn U,Kenn K

更新日期：2015-02-01 00:00:00

abstract：:Chronic obstructive pulmonary disease (COPD) is a chronic lung disease that is thought to affect over one million people in Great Britain. The main factor contributing to the development of COPD is tobacco smoke. This paper presents a microsimulation model for the development of COPD, incorporating population dynamics...

journal_title：Respiratory medicine

authors： Tan E,Boessen R,Fishwick D,Klein Entink R,Meijster T,Pronk A,van Duuren-Stuurman B,Warren N

更新日期：2015-12-01 00:00:00

abstract：INTRODUCTION:Dental caries and respiratory tract infections are among the most common infectious diseases worldwide and they both are appearing in the respiratory system. However, their relations are still unclear. This study investigated the association of dental caries on the risk of lower respiratory tract infection...

journal_title：Respiratory medicine

authors： Mehtonen IT,Rantala AK,Hugg TT,Jaakkola MS,Jaakkola JJK

更新日期：2019-01-01 00:00:00

abstract：:We have proposed a clinical treatment guideline for the management of acute, severe asthma and chronic obstructive pulmonarydisease (COPD) using the principles of evidence-based medicine. The content is based upon practical clinical issues in need of consensus. A previous study has shown that this particular area is i...

journal_title：Respiratory medicine

authors： Phanareth K,Hansen LS,Christensen LK,Laursen LC

更新日期：2002-09-01 00:00:00

abstract：:The principals of rehabilitation medicine are to prevent muscle atrophy and improve mobility. Exacerbations of chronic obstructive pulmonary disease (COPD) are associated with muscle atrophy and yet many patients do not undergo pulmonary rehabilitation until they have been in stable health for some time. We investigat...

journal_title：Respiratory medicine

authors： Murphy N,Bell C,Costello RW

更新日期：2005-10-01 00:00:00

abstract：OBJECTIVE:Positive end-expiratory pressure (PEEP) has been viewed as an essential component of mechanical ventilation in acute respiratory distress syndrome (ARDS) and acute lung injury (ALI). However, clinical trials have not yet convincingly demonstrated that high PEEP levels improve survival. The object of this stud...

journal_title：Respiratory medicine

authors： Oba Y,Thameem DM,Zaza T

更新日期：2009-08-01 00:00:00

abstract：PURPOSE:Although pulmonary rehabilitation (PR) improves function in people with chronic obstructive pulmonary disease (COPD), a community-based exercise program may be necessary to maintain functional capacity. We aimed to determine the effectiveness of a post-rehabilitation, community-based maintenance program on exer...

journal_title：Respiratory medicine

authors： Butler SJ,Desveaux L,Lee AL,Beauchamp MK,Brusco NK,Wang W,Goldstein RS,Brooks D

更新日期：2020-01-01 00:00:00

abstract：:Chlorofluorocarbon (CFC)-containing inhalers for use in the treatment of asthma are to be phased out under the terms of the Montreal Protocol (1). In this multi-centre, randomized, double-blind study, the therapeutic equivalence of two formulations of beclomethasone dipropionate (BDP) containing CFC or non-CFC (HFA134...

journal_title：Respiratory medicine

authors： Farmer IS,Middle M,Savic J,Perri VL,Herdman MJ

更新日期：2000-01-01 00:00:00

abstract：:Late allergic reactions (LAR) following allergen challenge occur in different compartments. We studied the kinetics of nasal and bronchial nitric oxide (NO) in mild asthmatics after allergen challenge. Twelve males with intermittent asthma (28 yr, FEV1 97% of predicted, PC20methacholine <8 mg/ml) and known LAR after b...

journal_title：Respiratory medicine

authors： Korn S,Beier J,Heilmann C,Kornmann O,Buhl R,Michael Beeh K

更新日期：2005-12-01 00:00:00

abstract：OBJECTIVE:To improve physicians' ability to discriminate tuberculous from malignant pleural effusions through a simple clinical algorithm that avoids pleural biopsy. DESIGN:We retrospectively compared the clinical and pleural fluid features of 238 adults with pleural effusion who satisfied diagnostic criteria for tube...

journal_title：Respiratory medicine

authors： Porcel JM,Alemán C,Bielsa S,Sarrapio J,Fernández de Sevilla T,Esquerda A

更新日期：2008-08-01 00:00:00

abstract：AIM:To examine tobacco use among teenagers, identify factors related to tobacco use, as well as evaluate the outcome of a smoking prevention program. METHODS:From age 7/8 to 14/15, annual questionnaires about asthma and allergy have been completed in the OLIN paediatric study in Northern Sweden. From 12/13 years, ques...

journal_title：Respiratory medicine

authors： Hedman L,Bjerg A,Perzanowski M,Sundberg S,Rönmark E

更新日期：2007-03-01 00:00:00

abstract：:Fifty patients with tropical eosinophilia were studied clinically and physiologically, before and after a standard 3-week course of diethylcarbamazine. Before treatment the main physiological abnormality was a reduction in the carbon monoxide transfer factor. One month after the start of treatment most patients had sh...

journal_title：Respiratory medicine

authors： Vijayan VK,Rao KV,Sankaran K,Venkatesan P,Prabhakar R

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:Combination therapy with inhaled corticosteroids (ICS) and long-acting β(2)-adrenergic agonists (LABA) is reported to have superior effects on controlling asthma symptoms to ICS alone; however, there is no molecular-based evidence to explain the clinical effects. Here, the effect of the ICS/LABA combination ...

journal_title：Respiratory medicine

authors： Essilfie-Quaye S,Ito K,Ito M,Kharitonov SA,Barnes PJ

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:GINA guideline recommends stepping down treatment of asthma patients where control is achieved. The aim of this analysis was to estimate the costs and health outcomes associated with step down of controlled patients on high dose fluticasone/salmeterol (FP/S 1000/100 μg daily) to either medium dose FP/S (500/...

journal_title：Respiratory medicine

authors： Paggiaro P,Patel S,Nicolini G,Pradelli L,Zaniolo O,Papi A

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Local and systemic inflammation is implicated in the pathophysiology of Obstructive Sleep Apnea (OSA). Exhaled breath condensate (EBC) is a non-invasive sampling method for the lower airways. However, it is important to consider the potential effect of the systemic origin whereas systemic inflammation is sig...

journal_title：Respiratory medicine

authors： Antonopoulou S,Loukides S,Papatheodorou G,Roussos C,Alchanatis M

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND:Stepping down from combination asthma therapy (inhaled corticosteroids (ICS) + long-acting β2 agonists (LABA)) is often avoided due to fear of exacerbations, which may lead to overmedication in well-controlled asthma. A better knowledge about the predictors of outcome might encourage clinicians to start step...

journal_title：Respiratory medicine

authors： Koskela HO,Purokivi MK,Kokkarinen J

更新日期：2016-08-01 00:00:00

abstract：:Various cells including polymorphonuclear leukocytes, alveolar macrophages and type-II pneumocytes may be a source of exhaled hydrogen peroxide (H2O2) in airways of humans. H2O2 can convert into hydroxyl radicals leading to peroxidative damage of airways structures and formation of volatile thiobarbituric acid-reactiv...

journal_title：Respiratory medicine

authors： Szkudlarek U,Maria L,Kasielski M,Kaucka S,Nowak D

更新日期：2003-06-01 00:00:00

abstract：OBJECTIVE:To investigate the usefulness of a self-reported respiratory health transition question over 10 years through reliability, ability to capture long-term asthma trajectory and predictive ability. SETTINGS:In two 20-year cohorts (Asthma-E3N, n = 16,371, 61-88 years; EGEA, n = 1254, 27-82 years), perceived 10-ye...

journal_title：Respiratory medicine

authors： Sanchez M,Varraso R,Bousquet J,Clavel-Chapelon F,Pison C,Kauffmann F,Humbert M,Siroux V

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:Lung fibrosis is attributed to derangements in extracellular matrix remodeling, a process driven by collagen turnover. We examined the association of two collagen biomarkers, carboxy-terminal telopeptide of collagen type I (ICTP) and amino-terminal propeptide of type III procollagen (PIIINP), with subclinica...

journal_title：Respiratory medicine

authors： Madahar P,Duprez DA,Podolanczuk AJ,Bernstein EJ,Kawut SM,Raghu G,Barr RG,Gross MD,Jacobs DR Jr,Lederer DJ

更新日期：2018-07-01 00:00:00

abstract：:Both albuterol and nedocromil sodium have been recognized to possess certain anti-inflammatory properties. However, there are no data on the impact of these drugs on the pathophysiology of the bronchial extracellular matrix in asthma characterized by enhanced tenascin (Tn) expression, known to occur proportional to th...

journal_title：Respiratory medicine

authors： Altraja A,Laitinen A,Meriste S,Marran S,Märtson T,Sillastu H,Laitinen LA

更新日期：1999-07-01 00:00:00

abstract：:In patients with asthma, exercise-induced symptoms are well recognized and frequently limiting. Currently available beta 2-receptor agonists have a short duration of action and breakthrough symptoms may occur. We studied the efficacy of the recently developed long acting inhaled beta 2-agonist salmeterol with respect ...

journal_title：Respiratory medicine

authors： Newnham DM,Ingram CG,Earnshaw J,Palmer JB,Dhillon DP

更新日期：1993-08-01 00:00:00

abstract：:During an epidemiological investigation of asthma in an occupational setting, 1126 subjects completed a modified Medical Research Council respiratory questionnaire, then underwent airway responsiveness measurements as PD20FEV1 to methacholine. Previous experience of bronchoconstriction was assessed in the 481 subjects...

journal_title：Respiratory medicine

authors： Stenton SC,Beach JR,Avery AJ,Hendrick DJ

更新日期：1995-03-01 00:00:00

abstract：BACKGROUND:Pleuroparenchymal fibroelastosis (PPFE) has been described in hypersensitivity pneumonitis (HP) yet its functional implications are unclear. Combined pulmonary fibrosis and emphysema (CPFE) has occasionally been described in never-smokers with HP, but epidemiological data regarding its prevalence is sparse. ...

journal_title：Respiratory medicine

authors： Jacob J,Odink A,Brun AL,Macaluso C,de Lauretis A,Kokosi M,Devaraj A,Desai S,Renzoni E,Wells AU

更新日期：2018-05-01 00:00:00

abstract：INTRODUCTION:Non-invasive positive pressure ventilation (NIPPV) is an effective treatment in respiratory failure. Continuous positive pressure (CPAP) may also be useful in acute hypoxaemic patients. Supplementary oxygen is usually necessary in both systems. However, the inspired oxygen fraction (FiO2) delivered by a NI...

journal_title：Respiratory medicine

authors： Samolski D,Antón A,Güell R,Sanz F,Giner J,Casan P

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:This study evaluated the dose-response and dosing interval of the novel long-acting muscarinic receptor antagonist (LAMA) GSK573719 in patients with COPD. METHODS:This randomized, double-blind, placebo-controlled, 3-way cross-over, incomplete block study evaluated 5 once-daily doses of GSK573719 (62.5-1000 ...

journal_title：Respiratory medicine

authors： Donohue JF,Anzueto A,Brooks J,Mehta R,Kalberg C,Crater G

更新日期：2012-07-01 00:00:00

abstract：:This study aims to investigate the possibility of additional value of leukotriene receptor antagonist (LTA) on dyspnea score, arterial blood gases (ABG), pulmonary function tests (PFTs), and quality of life (St. George QoL) in chronic obstructive pulmonary disease (COPD) patients. In this randomized, prospective, sing...

journal_title：Respiratory medicine

authors： Celik P,Sakar A,Havlucu Y,Yuksel H,Turkdogan P,Yorgancioglu A

更新日期：2005-04-01 00:00:00

abstract：:Prolonged cough is a common problem in patients seen in general practice. Using a simple method of sputum induction and processing of sputum samples, we determined whether eosinophilic airway inflammation could be a cause of undiagnosed prolonged cough. Eighty-two patients who had had cough for more than 1 month were ...

journal_title：Respiratory medicine

authors： Rytilä P,Metso T,Petäys T,Sohlman A,Työlahti H,Kohonen-Jalonen P,Kiviniemi P,Haahtela T

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Lung deposition of inhaled steroids, likely to be of benefit in the anti-inflammatory treatment of asthma in young children, is low. This is explained by age specific anatomical and physiological characteristics as well as poor cooperation with aerosol therapy. However, total lung deposition and the ratio of...

journal_title：Respiratory medicine

authors： Schueepp KG,Devadason SG,Roller C,Minocchieri S,Moeller A,Hamacher J,Wildhaber JH

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:Tracheal collapse is a weakness of the tracheal wall leading to expiratory central airway collapse of more than 50% compared to inspiration. It has previously been discussed whether the collapsibility of the greater airways is a stable or a dynamic condition. Indeed, other well-known lung diseases such as as...

journal_title：Respiratory medicine

authors： Nygaard M,Hilberg O,Rasmussen F,Bendstrup E

更新日期：2019-01-01 00:00:00