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Perceived 10-year change in respiratory health: reliability and predictive ability.

Abstract：

OBJECTIVE:To investigate the usefulness of a self-reported respiratory health transition question over 10 years through reliability, ability to capture long-term asthma trajectory and predictive ability. SETTINGS:In two 20-year cohorts (Asthma-E3N, n = 16,371, 61-88 years; EGEA, n = 1254, 27-82 years), perceived 10-year change in respiratory health ("Overall, in the last 10 years, do you think that your bronchial or respiratory health has changed?" if yes: "Has it improved/deteriorated?") was studied in relation with change in respiratory medication dispensation and lung function, with change in asthma status measured over the same period of time, and with subsequent asthma-related outcomes. RESULTS:Perceived deterioration (14% in Asthma-E3N) was associated with increased dispensations of respiratory medications over time (from 17% with >2 dispensations in 2004 to 26% in 2010). Report of perceived deterioration (13% in EGEA) was related to a lung function decline steeper by 9.3 mL/year as compared to perceived improvement. In both cohorts, change (improvement or deterioration) was more often perceived by participants with than without asthma (>45% vs <20%) and was dominant among participants with persistent current asthma (77%). Perceived deterioration was related to poorer asthma control 7 years later and to higher use of oral corticosteroids in the following 18 months. CONCLUSION:The proposed simple self-reported respiratory health transition question over 10 years allows predicting part of the long-term trajectory of asthma.

journal_name

Respir Med

journal_title

Respiratory medicine

authors

Sanchez M,Varraso R,Bousquet J,Clavel-Chapelon F,Pison C,Kauffmann F,Humbert M,Siroux V

doi

10.1016/j.rmed.2014.11.010

subject

Has Abstract

pub_date

2015-02-01 00:00:00

pages

188-99

issue

2

eissn

0954-6111

issn

1532-3064

pii

S0954-6111(14)00417-X

journal_volume

109

pub_type

杂志文章

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