Abstract:
:To investigate the effectiveness of nutritional supplement Bao Khi Khang as an adjuvant therapy in acute exacerbations of chronic obstructive pulmonary disease (COPD) compared to conventional therapy alone. This was a prospective, randomized, open-label controlled trial in 60 patients presenting with acute exacerbation of COPD. Patients were randomized into two groups, the control and the experimental groups. The control group was treated with the standard therapeutic protocol (Antimicrobial+Corticosteroids+Bronchodilator+Mucolytic drugs). The experimental group was treated with Bao Khi Khang tablets combined with the standard therapeutic protocol. The treatment outcomes, including clinical and paraclinical parameters of exacerbation of COPD, were compared between the experimental group and the control group at day 15 and 30. This study was conducted according to protocol: 01.2014-HTNCKH. The results showed a significant reduction of major COPD exacerbation symptoms in experimental group. The favorable progresses in mMRC scale and COPD Assessment Test score before and after treatment, between experimental group and control group, were statistically different. Symptom control such as cough, copious sputum secretion, and bacterial infection was 90% effective (very good 50.0%, good 40.0%) in experimental group compared to 50% (very good 20%, good 30.0%) in control group. No adverse side effects were observed in experimental group. Bao Khi Khang nutritional supplement could be an effective and safe adjuvant therapy in acute exacerbations of COPD. Further interventional studies are required to confirm these findings.
journal_name
J Med Foodjournal_title
Journal of medicinal foodauthors
Hoang BX,Han B,Nguyen HX,Dang KTdoi
10.1089/jmf.2017.0115subject
Has Abstractpub_date
2018-10-01 00:00:00pages
1053-1059issue
10eissn
1096-620Xissn
1557-7600journal_volume
21pub_type
杂志文章,随机对照试验abstract::Ganoderma lucidum has been widely used to treat various diseases, including cancer, diabetes, and neurasthenia in many Asian countries. This randomized, double-blind, placebo-controlled parallel study aimed to investigate the efficacy and safety of a polysaccharide extract of G. lucidum (Ganopoly) in Chinese patients ...
journal_title:Journal of medicinal food
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
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abstract::The medical ethnobotanical knowledge propagated over generations in the coastal regions of the Eastern Mediterranean, including Lebanon, is one that has built on several ancient cultures and civilizations of these regions. Recent interest in medical ethnobotany and the use of medicinal herbs in treating or preventing ...
journal_title:Journal of medicinal food
pub_type: 杂志文章,评审
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journal_title:Journal of medicinal food
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journal_title:Journal of medicinal food
pub_type: 杂志文章
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journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2014.0125
更新日期:2015-05-01 00:00:00
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journal_title:Journal of medicinal food
pub_type: 杂志文章
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journal_title:Journal of medicinal food
pub_type: 杂志文章
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abstract::Kimchi is a traditional Korean food manufactured by fermenting vegetables with probiotic lactic acid bacteria (LAB). Many bacteria are involved in the fermentation of kimchi, but LAB become dominant while the putrefactive bacteria are suppressed during salting of baechu cabbage and the fermentation. The addition of ot...
journal_title:Journal of medicinal food
pub_type: 杂志文章,评审
doi:10.1089/jmf.2013.3083
更新日期:2014-01-01 00:00:00
abstract::Essential to human health, selenium (Se) has enzymatic functions of fundamental importance to human biology due to its effects on DNA damage repair, its antioxidant properties, and cancer prevention. The best studied relationships between Se and the immune system is its role in the functions of neutrophils and of lymp...
journal_title:Journal of medicinal food
pub_type: 杂志文章,随机对照试验
doi:10.1089/jmf.2015.0145
更新日期:2016-06-01 00:00:00
abstract::Carob (Ceratonia siliqua L.) contains a wide variety of polyphenols with high antioxidant properties. In this study, we investigated the effects of aqueous extract of carob pods (AECP) on emotional behavior impairments and metabolic disorders in ovariectomized (OVX) rats. Female Wistar rats were assigned to three grou...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2019.0187
更新日期:2020-09-01 00:00:00
abstract::Esophageal cancer (EC) is commonly diagnosed in South Africa (SA), with high incidences occurring in SA's black population. Moringa oleifera (MO), a multipurpose tree, is used traditionally for its nutritional and medicinal properties. It has been used for the treatment of a variety of ailments, including cancer. We i...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2015.0113
更新日期:2016-04-01 00:00:00
abstract::Safety of intravenous (i.v.) or intrapulmonary administration of different concentrations of honey and their effects on blood sugar, renal and liver function tests, bone marrow function, lipid profile, and carbon tetrachloride (CCl(4))-induced liver damage were studied. Healthy sheep of either sex, 6-8 months old, wer...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/10966200360716652
更新日期:2003-10-01 00:00:00
abstract::Phenethyl isothiocyanate (PITC) is the hydrolysis product of the glucosinolate gluconasturtiin in cruciferous vegetables. This study was conducted to determine whether PITC inhibits 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced inflammation in the mouse ear. Topical application of 5 nmol of TPA to mouse ears mark...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2010.1296
更新日期:2011-04-01 00:00:00
abstract::The oxidation of lipids is an autocatalytic process consisting of a number of well-defined interrelated chemical reactions. Its importance has long been recognized in the food and polymer industry, and recent advances in the understanding of vascular diseases have shown that lipid peroxidation also contributes to huma...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.1999.2.163
更新日期:1999-01-01 00:00:00
abstract::With an increasing understanding of the health benefit of lycopene, how to preserve lycopene during food processing and storage has caused much attention. Lycopene belongs to the carotenoid family and mostly exists in nature as the all-trans form. Heat, light, oxygen, and different food matrices are factors that have ...
journal_title:Journal of medicinal food
pub_type: 杂志文章,评审
doi:10.1089/jmf.2005.8.413
更新日期:2005-01-01 00:00:00
abstract::In this article, we report the cloning of an aspartic protease (AP) from flowers of Arctium minus (Hill) Bernh. (Asteraceae) along with the use of depigmented aqueous flower extracts, as a source of APs, for the hydrolysis of whey proteins. The isolated cDNA encoded a protein product with 509 amino acids called arctiu...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2014.0101
更新日期:2015-08-01 00:00:00
abstract::Overwhelming evidence indicates that consumption of fruits and vegetables with antioxidant properties correlates with reduced risk for cancers, including leukemia. Carrots contain beneficial agents, such as β-carotene and polyacetylenes, which could be effective in the treatment of leukemia. This study investigated th...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2010.0284
更新日期:2011-11-01 00:00:00
abstract::Hyacinth bean, Dolichos lablab or Lablab purpureus, has been used for centuries in India and China as an edible pod and animal forage, as well as to treat diarrhea and other gastrointestinal disease in traditional Korean medicine. Recently, we have demonstrated that D. lablab extract (DLL-Ex) prevented free fatty acid...
journal_title:Journal of medicinal food
pub_type: 杂志文章
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abstract::Aerial parts of Medicago sativa L. have been used as food and its consumption has been associated with health benefits, one among the most important being menopausal symptoms control. This work was aimed to explore possible pharmacological effects of two new alfalfa-derived products that have recently emerged as daily...
journal_title:Journal of medicinal food
pub_type: 杂志文章
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abstract::This 12-week, double-blind, placebo-controlled study investigated the effects of fertilized egg powder (Young Tissue Extract; YT®) intake on outcome measures for depression. Fifty-five patients with depression were randomly assigned to receive YTE, YTE plus Melissa officinalis, or placebo for 12 weeks. At baseline, th...
journal_title:Journal of medicinal food
pub_type: 杂志文章,随机对照试验
doi:10.1089/jmf.2010.0146
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abstract::Adipose tissue is a key organ with substantial senescent cell accumulation under both obesity and aging conditions. Chia seed is an ancient seed and is the richest plant source of α-linolenic acid. We aimed to determine how cellular senescence markers will be altered in adipose tissue of senescence-accelerated mouse-p...
journal_title:Journal of medicinal food
pub_type: 杂志文章
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abstract::The leaves and pods of the drumstick tree are used as food and medicine in some Asian and African countries. Although relatively high concentrations of beta-carotene and lutein have been reported in the leaves, the bioavailability of these carotenoids from this source is unknown. We have analyzed the digestive stabili...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2006.250
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abstract::The anti-ulcer potentials of aqueous (AE) and methanol (ME) extracts of whole unripe Carica papaya fruit were evaluated using ethanol- and indomethacin-induced gastric ulcer models in rats. The effect of the extracts on small intestinal propulsion was also investigated. The extracts significantly reduced the ulcer ind...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2008.0197
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abstract::Aqueous extracts of Gynura procumbens (Lour.) Merr. were orally administered to spontaneously hypertensive (SHR) rats for 4 weeks, and antihypertensive effects were determined. Oral administration of 500 mg/kg of G. procumbens (Lour.) Merr. extract (GPE) resulted in significantly lower blood pressure in SHR rats compa...
journal_title:Journal of medicinal food
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doi:10.1089/jmf.2006.9.587
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abstract::Red ginseng (Panax ginseng C.A. Meyer) is the most widely recognized medicinal herb due to its remedial effects in various disorders, such as cancers, diabetes, and heart problems. In this study, we investigated the anticancer effect of fermented red ginseng extract (f-RGE; provided by Jeonju Biomaterials Institute, J...
journal_title:Journal of medicinal food
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abstract::Telfairia occidentalis (fluted pumpkin) is one of the commonly consumed leafy vegetables in Nigeria. In order to justify its inclusion in herbal preparations in African traditional medicine, the possible hypolipidemic effect of this vegetable was investigated in rats fed a cholesterol-rich diet. The ability of Questra...
journal_title:Journal of medicinal food
pub_type: 杂志文章
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abstract::This study was designed to investigate the effect of heating, storage, and ultraviolet exposure on antimicrobial activity of garlic juice and its bacteriocidal activity against common human pathogens. Antimicrobial activity of fresh garlic juice was tested against Escherichia coli, Staphylococcus aureus, Streptococcus...
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abstract::Glyceollins, which are derived from daidzein in soybean in response to various stimuli or stresses, have been reported to activate antioxidant/detoxifying enzymes in a nuclear factor (erythroid-derived 2)-like 2 (Nrf2)-dependent manner, in addition to exerting anti-inflammatory effects in murine macrophages. As the Nr...
journal_title:Journal of medicinal food
pub_type: 杂志文章
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abstract::Dietary patterns high in fat influence local and systemic oxidative stress through adipose tissue (AT) accrual and increased reactive oxygen species generation. Lycopene, a carotenoid with antioxidant functionality, may mitigate excess oxidative stress, yet the lipophilic nature of this compound may limit its function...
journal_title:Journal of medicinal food
pub_type: 杂志文章
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abstract::Problems associated with current treatment regimens have generated a considerable interest in alternative approaches for the eradication of Helicobacter pylori infections using phytochemical compounds. In an attempt to identify potential sources of such compounds, the antimicrobial activity of five solvent extracts of...
journal_title:Journal of medicinal food
pub_type: 杂志文章
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