Sex-specific differences in cannabinoid-induced extracellular-signal-regulated kinase phosphorylation in the cingulate cortex, prefrontal cortex, and nucleus accumbens of Lister Hooded rats.

abstract：:The present experiments investigated the validity and utility of measuring the habituation of a nose-poke response to assess memory in mice. Mice were placed in an operant chamber equipped with two holes in one wall. Nose-poke responses were recorded by the interruption of a photo-beam across the openings of the holes...

journal_title：Behavioural pharmacology

authors： Brodkin J

更新日期：1999-09-01 00:00:00

abstract：:Baclofen has shown promise in treating substance use disorders and also reduced binge frequency in an open-label trial. This placebo-controlled, double-blind, crossover study further assessed the effects of baclofen on binge eating. Twelve individuals who self-reported binge eating completed the study. Data were colle...

journal_title：Behavioural pharmacology

authors： Corwin RL,Boan J,Peters KF,Ulbrecht JS

更新日期：2012-09-01 00:00:00

abstract：:In a previous short-term study, salvianolic acid B was reported to have a protective effect on cerebral ischemia. Here, we investigated whether salvianolic acid B improves the recovery of motor function after cerebral ischemia in a 14-day investigation. Cerebral ischemia was induced by middle cerebral artery occlusion...

journal_title：Behavioural pharmacology

authors： Tang M,Feng W,Zhang Y,Zhong J,Zhang J

更新日期：2006-09-01 00:00:00

abstract：:Ultrasonic vocalizations are widely used to examine affective states in rats, yet relatively few studies explore the acoustic features of vocalizations, especially in relation to drug exposure, and no studies have explored alterations in acoustic features over time. The goal of this study was to examine nicotine- and ...

journal_title：Behavioural pharmacology

authors： Swalve N,Mulholland MM,Li M

更新日期：2019-08-01 00:00:00

abstract：:Parkinson's disease (PD) is a neurodegenerative disorder classically associated with motor symptoms, but several nonmotor disturbances appear decades before the clinical diagnosis of the disease. A variety of hypotheses exist to explain the onset of PD, and neuroinflammation is one of the most investigated processes. ...

journal_title：Behavioural pharmacology

authors： Rodrigues LS,Fagotti J,D S Targa A,D Noseda AC,L Ilkiwa J,Chuproski AP,W C Dorieux F,D Dos Santos P,M S Lima M

更新日期：2019-12-01 00:00:00

abstract：:Alcohol consumption acutely increases smoking behavior, but the reverse relationship, the acute effects of smoking on alcohol intake, largely has been ignored. We examined whether smoking acutely increases the reinforcing value of alcohol, first in the absence of recent alcohol intake and then following an alcohol pre...

journal_title：Behavioural pharmacology

authors： Perkins KA,Fonte C,Grobe JE

更新日期：2000-02-01 00:00:00

abstract：:Neuropsychiatric disorders, such as addiction, are associated with cognitive impairment, including learning and memory deficits. Previous research has demonstrated that the chronic use of methamphetamine (METH) induces long-term cognitive impairment and cannabidiol (CBD), as a neuroprotectant, can reverse spatial memo...

journal_title：Behavioural pharmacology

authors： Razavi Y,Shabani R,Mehdizadeh M,Haghparast A

更新日期：2020-06-01 00:00:00

abstract：:Appetitive behaviours occur in a state of behavioural and physiological activation that allows the optimal performance of these goal-directed behaviours. Here, we tested the hypothesis that histamine neurons under the command of the infralimbic cortex are important to provide behavioural activation. Extracellular hist...

journal_title：Behavioural pharmacology

authors： Riveros ME,Forray MI,Torrealba F

更新日期：2015-06-01 00:00:00

abstract：:Previous studies have shown that ethanol produces conditioned place preference (CPP) in mice when injections are given immediately before exposure to the conditioned stimulus (CS). Paradoxically, however, injection of ethanol immediately after the CS produces conditioned place aversion (CPA). Four experiments were con...

journal_title：Behavioural pharmacology

authors： Cunningham CL,Henderson CM

更新日期：2000-11-01 00:00:00

abstract：:A symposium held at the 50th annual meeting of the Behavioral Pharmacology Society in May 2007 reviewed progress in the human behavioral pharmacology of drug abuse. Studies on drug self-administration in humans are reviewed that assessed reinforcing and subjective effects of drugs of abuse. The close parallels observe...

journal_title：Behavioural pharmacology

authors： Comer SD,Bickel WK,Yi R,de Wit H,Higgins ST,Wenger GR,Johanson CE,Kreek MJ

更新日期：2010-07-01 00:00:00

abstract：:The interactions of -adrenoceptors and acute restraint stress with morphine state-dependent memory of passive avoidance were examined in mice. Memory acquired following pre-training morphine administration (5 mg/kg, i.p.) was dose- and time-dependently retrieved by pre-test morphine; this effect was reversible by yohi...

journal_title：Behavioural pharmacology

authors： Homayoun H,Khavandgar S,Zarrindast MR

更新日期：2003-02-01 00:00:00

abstract：:In previous studies, it was shown that apomorphine-induced stereotyped behaviour could be conditioned when apomorphine was repeatedly paired with sensory stimuli (CS). Since in these experiments, the sum of various sensory stimuli were applied, it seemed of interest to use each sensory stimulus separately in order to ...

journal_title：Behavioural pharmacology

authors： Ferger B,Kuschinsky K

更新日期：1995-01-01 00:00:00

abstract：:Nitrous oxide (N2O) effects were evaluated, as a behavioural model of inert gas narcosis, in rats performing a vigilance task in which they were required to respond to a slight luminous increment of the house-light. A dose-related decrease of correct responses was produced by the tested range of concentrations of N2O ...

journal_title：Behavioural pharmacology

authors： Courtière A,Hardouin J

更新日期：1997-10-01 00:00:00

abstract：:Rats were maintained on a daily regimen involving a 2h opportunity to take both water and a sweetened alcoholic beverage (12% ethanol, 0.25% saccharin). After 3 weeks on this regimen, rats regularly take substantial amounts of alcohol. After stabilization, injections of alpha(2)-adrenergic antagonists were administere...

journal_title：Behavioural pharmacology

authors： Reid LD,Delconte JD,Amendola CA,Nichols ML,Krupsky GW,Dharia NS,Hubbell CL

更新日期：1994-08-01 00:00:00

abstract：:Behavioral sensitization to amphetamine-like psychostimulants is manifest as a progressive increase in drug-induced anxiety and paranoia which can culminate in psychopathologies, such as paranoid psychosis and panic attacks. Sensitization may also mediate the facilitation of drug relapse in addicts by increasing the r...

journal_title：Behavioural pharmacology

authors： Kalivas PW,Sorg BA,Hooks MS

更新日期：1993-01-01 00:00:00

abstract：:A previous study from this laboratory reported an antiaversive effect of the beta-adrenoceptor blocker propranolol microinjected into the dorsal periaqueductal grey (DPAG) of the rat, that was antagonized by the 5-HT(2) receptor blocker ritanserin. The present results show that microinjection into the DPAG of isamolta...

journal_title：Behavioural pharmacology

authors： Nogueira RL,Graeff FG

更新日期：1991-02-01 00:00:00

abstract：:The interoceptive stimulus induced by clozapine (5 mg/kg, i.p.) has been characterized in an operant drug discrimination procedure in the rat using a wide range of receptor subtype-selective agonists and antagonists. Only the muscarinic receptor antagonist scopolamine generalized fully to clozapine (>80%). Partial gen...

journal_title：Behavioural pharmacology

authors： Goudie AJ,Smith JA,Taylor A,Taylor MA,Tricklebank MD

更新日期：1998-12-01 00:00:00

abstract：:The prototypic cannabinoid CB1 antagonist SR 141716A is one important pharmacologic tool for examining CB1 receptors that mediate the behavioral and physiologic effects of delta9-tetrahydrocannabinol (delta9-THC). This study examined the effects of SR 141716A on the rate-decreasing, hypothermic and discriminative stim...

journal_title：Behavioural pharmacology

authors： McMahon LR,Amin MR,France CP

更新日期：2005-09-01 00:00:00

abstract：:Fragile X syndrome is an X-linked form of mental retardation including, among others, symptoms such as stereotypic behaviour, hyperactivity, hyperarousal, and cognitive deficits. We hypothesized that hyperactivity and/or compromised attentional, cognitive functions may lead to impaired performance in cognitive tasks i...

journal_title：Behavioural pharmacology

authors： Ventura R,Pascucci T,Catania MV,Musumeci SA,Puglisi-Allegra S

更新日期：2004-09-01 00:00:00

abstract：:Effects of environmental modulation of methamphetamine (MA)-induced behavior on the establishment and mode of expression of behavioral sensitization were examined. Rats received daily injection of MA for 10 days (1mg/kg, s.c.). Half of them were immediately returned to the home cage (home cage group) and the other hal...

journal_title：Behavioural pharmacology

authors： Ohmori T,Abekawa T,Koyama T

更新日期：1995-03-01 00:00:00

abstract：:Serotonin-selective reuptake inhibitors (SSRIs) have been shown to enhance the locomotor stimulatory, discriminative-stimulus, and convulsive effects of cocaine in rodents. A pharmacokinetic mechanism for the interaction is supported by increases in the brain levels of cocaine by fluoxetine treatment. Furthermore, the...

journal_title：Behavioural pharmacology

authors： Soto PL,Hiranita T,Katz JL

更新日期：2009-12-01 00:00:00

abstract：:Treatments for the positive and negative symptoms of schizophrenia have been explored for decades, but no completely successful therapy has been found as yet. Metabotropic glutamate receptor 5 (mGluR5), which potentiates N-methyl-D-aspartate receptors in brain regions implicated in schizophrenia, has become a novel dr...

journal_title：Behavioural pharmacology

authors： Wu Z,Yang Z,Zhang M,Bao X,Han F,Li L

更新日期：2018-02-01 00:00:00

abstract：:Drug withdrawal is often conceptualized as an aversive state that motivates drug-seeking and drug-taking behaviors in humans. Stress is more difficult to define, but is also frequently associated with aversive states. Here we describe evidence for the simple theory that drug withdrawal is a stress-like state, on the b...

journal_title：Behavioural pharmacology

authors： Chartoff EH,Carlezon WA Jr

更新日期：2014-09-01 00:00:00

abstract：:This study was conducted to evaluate the effects of exposure to diphenyl diselenide (PhSe)2 on cognitive impairment induced by scopolamine, a muscarinic antagonist, using the Y-maze and Morris water maze tests in mice. One hour before the tests, mice were treated with (PhSe)2 (50 mg/kg, oral) and 30 min later memory i...

journal_title：Behavioural pharmacology

authors： Souza AC,Brüning CA,Leite MR,Zeni G,Nogueira CW

更新日期：2010-09-01 00:00:00

abstract：:The purpose of this experiment was to examine the substitution patterns produced by opioids with activity at the mu receptor in pigeons trained to discriminate the delta opioid BW373U86 from saline. A low dose of naltrindole (0.1 mg/kg) produced at least a 16-fold rightward shift in the dose-effect curve for the stimu...

journal_title：Behavioural pharmacology

authors： Picker MJ,Cook CD

更新日期：1998-07-01 00:00:00

abstract：:Sensorimotor gating disruptions are seen in various psychiatric illnesses with putatively different pathologies, including schizophrenia and bipolar disorder. Interestingly, mice lacking the dopamine (DA) transporter (DAT) gene display markedly increased levels of DA, deficits in sensorimotor gating, and hyperactivity...

journal_title：Behavioural pharmacology

authors： Powell SB,Young JW,Ong JC,Caron MG,Geyer MA

更新日期：2008-09-01 00:00:00

abstract：:Rats were given fixed-time, 1-min food-pellet delivery sessions, for 3 h every day, which resulted in over drinking (schedule-induced polydipsia). In previous research, groups of animals came to prefer solutions of cocaine or lidocaine to concurrently presented water, if the drugs were first offered in a glucose/sacch...

journal_title：Behavioural pharmacology

authors： Falk JL,Yosef E,Schwartz A,Lau CE

更新日期：1999-02-01 00:00:00

abstract：:Few studies have investigated the effects of chronic cannabinoid exposure on memory performance and whether tolerance occurs to cannabinoid-induced memory impairment. Here, we studied the effects of repeated exposure to Delta-tetrahydrocannabinol (THC: 1 mg/kg) on spatial memory and zif268 expression in mice. One grou...

journal_title：Behavioural pharmacology

authors： Boucher AA,Vivier L,Metna-Laurent M,Brayda-Bruno L,Mons N,Arnold JC,Micheau J

更新日期：2009-02-01 00:00:00

abstract：:There is a growing realization that the severity of the core symptoms of autism spectrum disorders and schizophrenia is associated with gastrointestinal dysfunction. Nonetheless, the mechanisms underlying such comorbidities remain unknown. Several genetic and environmental factors have been linked to a higher suscepti...

journal_title：Behavioural pharmacology

authors： Morais LH,Felice D,Golubeva AV,Moloney G,Dinan TG,Cryan JF

更新日期：2018-04-01 00:00:00

abstract：:The non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist dizocilpine (MK-801) (0.08 and 0.12 mg/kg, i.p.) was used to examine whether spatial memory is learned state-dependently. Rats pre-treated with drug or saline were trained for 9 days in an eight-arm radial maze, in which four arms were baited. On the ...

journal_title：Behavioural pharmacology

authors： Kretschmer BD,Fink S

更新日期：1999-07-01 00:00:00