Is dietary fibre truly protective against colon cancer? A systematic review and meta-analysis.

Abstract:

:Colorectal cancer is the third most common cancer worldwide. Growing evidence shows that about 47% of cases of colorectal cancer can be prevented by a healthy lifestyle. We performed a systematic review and meta-analysis aimed to evaluate the association between dietary fibre intake and the risk of colon cancer. We performed a structured computer search on PubMed, including epidemiological studies reporting results of dietary fibre intake and risk of colon cancer in women or men. We compared subjects exposed to the highest versus the lowest consumption. The search strategy identified 376 papers. After screening, 25 datasets were included in our meta-analysis. Results suggest a protective role of dietary fibre intake on colon cancer risk ES = 0.74 (95% CI = 0.67-0.82), p value = .000, but, moderate statistical heterogeneity (χ2 = 42.73, p value = .011) was found. Due to the high mortality of colorectal cancer, it is important to identify effective preventive measures, especially those of a healthy lifestyle, such as a healthy diet.

journal_name

Int J Food Sci Nutr

authors

Gianfredi V,Salvatori T,Villarini M,Moretti M,Nucci D,Realdon S

doi

10.1080/09637486.2018.1446917

subject

Has Abstract

pub_date

2018-12-01 00:00:00

pages

904-915

issue

8

eissn

0963-7486

issn

1465-3478

journal_volume

69

pub_type

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