Characterization of uncommon portosystemic collateral circulations in patients with hepatic cirrhosis.

abstract：:Human umbilical cord-derived mesenchymal stem cells (hUCMSCs) represent potential therapeutic tools for solid tumors. However, there are numerous inconsistent results regarding the effects of hUCMSCs on tumors, and the mechanisms underlying this remain poorly understood. The present study further examined this controv...

journal_title：Oncology letters

authors： Yuan Y,Zhou C,Chen X,Tao C,Cheng H,Lu X

更新日期：2018-06-01 00:00:00

abstract：:Peroxiredoxin (Prx) II is an imperative member of the superfamily of peroxidases. It serves an essential role in scavenging organic hydroperoxide and H2O2. It is involved in the development of various malignant tumors. In order to investigate the significance of Prx II expressions level in gastric cancer (GC), downreg...

journal_title：Oncology letters

authors： Niu L,Liu A,Xu W,Yang L,Zhu W,Gu Y

更新日期：2018-10-01 00:00:00

abstract：:The aim of the present study was to identify genes that may serve as markers for breast cancer prognosis by constructing a gene co-expression network and mining modules associated with survival. Two gene expression datasets of breast cancer were downloaded from ArrayExpress and genes from these datasets with a coeffic...

journal_title：Oncology letters

authors： Shi H,Zhang L,Qu Y,Hou L,Wang L,Zheng M

更新日期：2017-10-01 00:00:00

abstract：:Clinical application value was investigated of transvaginal color Doppler ultrasound (TV-CDS) combined with serum tumor markers carbohydrate antigen 125 (CA125), vascular endothelial growth factor (VEGF) and osteopontin (OPN) in the diagnosis of ovarian cancer (OC). One hundred and six patients with OC [malignant tumo...

journal_title：Oncology letters

authors： Yu C,Dou T,Liu Y,Liu R

更新日期：2020-08-01 00:00:00

abstract：:Skeletal muscle is rich in lymphatic vessels, with an abundant blood supply, and it is an infrequent site of cancer metastasis. Previous studies have demonstrated that enhanced secretion of MyoD may occur when skeletal muscle is injured or becomes cancerous. It was hypothesized that MyoD may act as an endogenous cytok...

journal_title：Oncology letters

authors： Cai C,Qin X,Wu Z,Shen Q,Yang W,Zhang S,Duan J,Liang F,Liu C

更新日期：2016-06-01 00:00:00

abstract：:The development of upper tract urothelial carcinoma (UTUC) has been associated with the ingestion of aristolochic acid (AA) in Chinese herbs. The tumors are more malignant and patients have a worse prognosis in China compared with that in Western countries. Recently, whole-genome and exome sequencing of AA-associated ...

journal_title：Oncology letters

authors： Wang Y,Zhang JX,Wang SF,Zhang Y,He HY

更新日期：2020-12-01 00:00:00

abstract：:The aim of the present study was to investigate the effect of HPV16E6 gene integration on the biological behavior of Eca109 and Eca9706 cells. This was evaluated through positive liposome transfection of HPV16E6 into Eca109 cells and Eca9706 cells. The transfection efficiency was evaluated by calculating the ratio of ...

journal_title：Oncology letters

authors： Kang XD,Zheng Y,Chen WG,Cheng M,Zhang D

更新日期：2018-02-01 00:00:00

abstract：:Pyruvate kinase isoenzyme M2 (PKM2) has previously been identified as a tumor biomarker and potential therapeutic target for the treatment of cancer. In the present study, FFJ-3, a structurally modified version of mollugin, an extract of the Traditional Chinese herbal medicine Rubia tinctorum (madder) was used in orde...

journal_title：Oncology letters

authors： Li D,Wei X,Ma M,Jia H,Zhang Y,Kang W,Wang T,Shi X

更新日期：2017-04-01 00:00:00

abstract：:The incidence of intussusception is low in adults, particularly in the descending colon, due to the anatomical attachment of the descending colon to the retroperitoneum. Signet ring cell histology represents ~1% of colon adenocarcinomas and is associated with young patients and a poor clinical outcome. The present stu...

journal_title：Oncology letters

authors： Sun KK,Yang D,Gan M,Wu XY

更新日期：2015-03-01 00:00:00

abstract：:Previous studies have revealed the aberrant expression of a number of microRNAs (miRNA/miRs) in the blood circulation of patients with breast cancer (BC). The aim of the present study was to assess the effect of neoadjuvant chemotherapy on the levels of a panel of BC-associated miRNAs, which are at relatively low (let...

journal_title：Oncology letters

authors： Gezer U,Keskin S,Iğci A,Tükenmez M,Tiryakioğlu D,Cetinkaya M,Dişci R,Dalay N,Eralp Y

更新日期：2014-08-01 00:00:00

abstract：:The putative oncogenic role of ATP/GTP binding protein like 2 (AGBL2) in catalyzing α-tubulin detyrosination has recently been characterized in cancer. However, the status of AGBL2 expression in ovarian cancer and its potential clinical and prognostic significance remain unclear. In the present study, immunohistochemi...

journal_title：Oncology letters

authors： He WP,Wang LL

更新日期：2019-11-01 00:00:00

abstract：:Decoy receptor 3 (DcR3) is a tumor necrosis factor receptor, which may inhibit apoptosis. The aim of the present study was to investigate the clinical significance of DcR3 upregulation in patients with chronic hepatitis B (CHB) and hepatic fibrosis. A total of 128 patients with a clinical diagnosis of CHB who underwen...

journal_title：Oncology letters

authors： Lou X,Hou Y,Cao H,Zhao J,Zhu F

更新日期：2018-07-01 00:00:00

abstract：:Management of multinodular hepatocellular carcinoma (HCC) in the intermediate Barcelona Clinic Liver Cancer (BCLC)-B stage is controversial. The aim of the present study as to identify the subgroup of patients with BCLC-B HCC who could benefit from liver resection. The present study retrospectively analyzed the outcom...

journal_title：Oncology letters

authors： Matsukuma S,Sakamoto K,Tokuhisa Y,Tokumitsu Y,Matsui H,Kanekiyo S,Tomochika S,Iida M,Suzuki N,Takeda S,Ueno T,Wada H,Kobayashi S,Saeki I,Eguchi H,Sakon M,Sakaida I,Nagano H

更新日期：2018-11-01 00:00:00

abstract：:Resistance to oxaliplatin (L-OHP) is a major obstacle to successful chemotherapy in colorectal cancer (CRC). In the present study, the ability of gambogic acid (GA) to reverse L-OHP resistance in CRC LoVo cells was investigated. L-OHP-resistant LoVo/L-OHP cells were established by exposing them to increasing concentra...

journal_title：Oncology letters

authors： Wang Q,Wei J,Wang C,Zhang T,Huang D,Wei F,He F,Cai W,Yang P,Zeng S,Li W,Cao J

更新日期：2018-08-01 00:00:00

abstract：:Increasing numbers of extrapleural solitary fibrous tumours (SFTs), including the prostate SFT, have been reported over the last 10-years. Prostate SFT is relatively uncommon, with <20 cases reported in the literature worldwide. In the present study, a prostate SFT case, which was initially misdiagnosed as benign pros...

journal_title：Oncology letters

authors： Yang W,Sun F,Liu H,Wang G,Shi P,Shao Z,Guo F

更新日期：2015-09-01 00:00:00

abstract：:Gastric cancer is a common malignancy in China, with the second highest mortality rate worldwide. Advanced gastric cancer usually exhibits a poor prognosis with a low 5-year survival rate. Therefore, developing novel drugs for the treatment of this cancer will be beneficial for patients. Demethylzeylasteral, an extrac...

journal_title：Oncology letters

authors： Yang Y,Zhao M,Hu T,Su F,Qian F,Wang Z

更新日期：2021-01-01 00:00:00

abstract：:Comprehensive gene screening with transposons is a novel procedure for the systematic identification of resistant genes. The present study aimed to use this technique to identify candidate radioresistant genes in esophageal squamous cell carcinoma. A transposon is a base sequence that can translocate to another locati...

journal_title：Oncology letters

authors： Takesue T,Kawakubo H,Hayashida T,Tsutsui M,Miyao K,Fukuda K,Nakamura R,Takahashi T,Wada N,Takeuchi H,Kitagawa Y

更新日期：2017-10-01 00:00:00

abstract：:Targeted therapy of non-small cell lung cancer (NSCLC) patients with mutations in the epidermal growth factor receptor (EGFR) gene has been associated with improved prognosis. However, there is a shortage on data from real-world clinical practice in management of EGFR-positive NSCLC patients in Poland. The present stu...

journal_title：Oncology letters

authors： Ramlau R,Krawczyk P,Dziadziuszko R,Chmielewska I,Milanowski J,Olszewski W,Stencel K,Ramlau-Piątek K,Segiet A,Skroński M,Grudny J,Chorostowska-Wynimko J

更新日期：2017-11-01 00:00:00

abstract：:Severe hemorrhage following a prostatectomy is a rare and serious complication. A 63-year-old male with severe hemorrhage following radical prostatectomy which led to hypovolemic shock presented at our department and was treated with superselective internal iliac arterial embolization. At 6 months follow-up, the patie...

journal_title：Oncology letters

authors： Cheng S,Xu L,Li G,Chen Y,Hu H,Zhang Z,Ding G

更新日期：2012-09-01 00:00:00

abstract：:FP3 (KH902/KH903) is a novel vascular endothelial growth factor (VEGF) blocker with antiangiogenic properties. Previous studies revealed that FP3, a humanized fusion protein that combines ligand binding elements from the extracellular domains of VEGF receptors 1 and 2 and the Fc portion of IgG1, has an inhibitory effe...

journal_title：Oncology letters

authors： Jin K,Lan H,Cao F,Xu Z,Han N,Li G,He K,Teng L

更新日期：2012-05-01 00:00:00

abstract：:It is unclear how microRNA (miR)-494 inhibits the proliferation of cervical cancer cells by altering the expression of SOCS6. Therefore, the present study aimed to investigate the molecular mechanism underlying miR-494 regulation of suppressor of cytokine signaling 6 (SOCS6) in human cervical cancer samples and the hu...

journal_title：Oncology letters

authors： Cheng L,Kong B,Zhao Y,Jiang J

更新日期：2018-03-01 00:00:00

abstract：:Osteosarcoma is a malignant tumor derived from the skeletal system, often occurring in bone tissues, and it is the most common malignant tumor in the skeletal system, with more than 90% of cases being highly malignant. The present study was designed to explore the regulatory effects of microRNA (miR)-19a on the prolif...

journal_title：Oncology letters

authors： Chen J,Chen Z

更新日期：2020-11-01 00:00:00

abstract：:For individualized bevacizumab-based therapy, non-invasive biomarkers are necessary. This study assessed the predictive value of plasma vascular endothelial growth factor (VEGF)-A, soluble VEGF receptor (sVEGFR)-1 and sVEGFR-2 levels as biomarkers for clinical response and survival in advanced colorectal cancer (CRC) ...

journal_title：Oncology letters

authors： Aoyagi Y,Iinuma H,Horiuchi A,Shimada R,Watanabe T

更新日期：2010-03-01 00:00:00

abstract：:The aim of the study was to determine whether interleukin-8 (IL-8) affects human SKOV3 ovarian cancer cell migration and invasion by targeting silencing of IL-8 expression. Silencing small-interfering RNA (siRNA) targeting IL-8 gene was constructed to infect SKOV3 cells by lentiviral vector. The expression of IL-8 and...

journal_title：Oncology letters

authors： Li Y,Liu L,Yin Z,Xu H,Li S,Tao W,Cheng H,Du L,Zhou X,Zhang B

更新日期：2017-02-01 00:00:00

abstract：:Cell adhesion molecule (CADM) genes encode immunoglobulin superfamily molecules, which are involved in cell-cell adhesion in a number of human epithelia. Through the maintenance of epithelia, CADM genes protect against malignant conversion and metastasis. Whilst numerous in vitro studies have investigated the molecula...

journal_title：Oncology letters

authors： Saito M,Goto A,Abe N,Saito K,Maeda D,Ohtake T,Murakami Y,Takenoshita S

更新日期：2018-02-01 00:00:00

abstract：:Aquaporin 5 (AQP5), a water channel protein, is highly expressed in non-small cell lung cancer (NSCLC) tissues compared with adjacent normal tissues. AQP5 expression in lung cancer tissues is associated with a poor prognosis. The present study aimed to analyze the expression of AQP5 and investigate its role in primary...

journal_title：Oncology letters

authors： Song T,Yang H,Ho JC,Tang SC,Sze SC,Lao L,Wang Y,Zhang KY

更新日期：2015-06-01 00:00:00

abstract：:The aim of the present study was to investigate whether ultrasound combined with microbubbles was able to enhance liposome-mediated transfection of genes into human prostate cancer cells, and to examine the association between autophagy and tumor protein P53 (P53). An MTT assay was used to evaluate cell viability, whi...

journal_title：Oncology letters

authors： Wang YU,Chen YN,Zhang W,Yang YU,Bai WK,Shen E,Hu B

更新日期：2016-01-01 00:00:00

abstract：:Radiotherapy, particularly the target delineation of cancer based on scanned images, plays a key role in the planning of cancer treatment. Recently, diffusion-weighted magnetic resonance imaging (DW-MRI) has emerged as a prospective superior procedure compared with intensified computed tomography (CT) and positron emi...

journal_title：Oncology letters

authors： Zhang X,Fu Z,Gong G,Wei H,Duan J,Chen Z,Chen X,Wang R,Yin Y

更新日期：2017-09-01 00:00:00

abstract：:Lymph node metastasis is the primary site of metastasis for patients with gallbladder cancer (GBC). Vascular endothelial growth factor-C (VEGF-C) has been implicated in the control of lymphangiogenesis and lymph node metastasis in various malignant tumors. However, the function of circulating VEGF-C is unclear and it ...

journal_title：Oncology letters

authors： Jiang L,Liu M,Cai X,Xie L,She F,Chen Y

更新日期：2018-11-01 00:00:00

abstract：:Mangiferin, a flavonoid extracted from the mango tree, possesses anti-inflammatory, antibacterial, anti-herpes simplex and antitumor activity, and is able to affect immune function. The present study investigated the anticancer effects of mangiferin treatment on PC3 human prostate cancer cells, and the potential under...

journal_title：Oncology letters

authors： Li M,Ma H,Yang L,Li P

更新日期：2016-01-01 00:00:00