Implementation of diffusion-weighted magnetic resonance imaging in target delineation of central lung cancer accompanied with atelectasis in precision radiotherapy.

Abstract:

:Radiotherapy, particularly the target delineation of cancer based on scanned images, plays a key role in the planning of cancer treatment. Recently, diffusion-weighted magnetic resonance imaging (DW-MRI) has emerged as a prospective superior procedure compared with intensified computed tomography (CT) and positron emission tomography (PET) in the target delineation of cancer. However, the implication of DW-MRI in lung cancer, the leading cause of cancer-associated mortality worldwide, has not been extensively evaluated. In the present study, the gross target volumes of lung cancer masses delineated using the DW-MRI, CT and PET procedures were compared in a pairwise manner in a group of 27 lung cancer patients accompanied with atelectasis of various levels. The data showed that compared with CT and PET procedures, DW-MRI has a more precise delineation of lung cancer while exhibiting higher reproducibility. Together with the fact that it is non-invasive and cost-effective, these data demonstrate the great application potential of the DW-MRI procedure in cancer precision radiotherapy.

journal_name

Oncol Lett

journal_title

Oncology letters

authors

Zhang X,Fu Z,Gong G,Wei H,Duan J,Chen Z,Chen X,Wang R,Yin Y

doi

10.3892/ol.2017.6479

subject

Has Abstract

pub_date

2017-09-01 00:00:00

pages

2677-2682

issue

3

eissn

1792-1074

issn

1792-1082

pii

OL-0-0-6479

journal_volume

14

pub_type

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