Review article: coeliac disease in later life must not be missed.

abstract：BACKGROUND:There is expanding interest in the role that diet plays in ileoanal pouch function and in the pathogenesis of pouchitis. AIMS:To present a narrative review of published literature regarding the relationship of diet with pouch function and the pathogenesis of pouchitis, and to provide potentially beneficial ...

journal_title：Alimentary pharmacology & therapeutics

authors： Ardalan ZS,Yao CK,Sparrow MP,Gibson PR

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:The long-term outcome of percutaneous acetic acid injection (PAI) and percutaneous ethanol injection (PEI) for treating small hepatocellular carcinoma (HCC) remains unclear. AIM:To compare the long-term outcome of PAI vs. PEI for treating small HCC. METHODS:From July 1998 to July 2004, 125 patients with sm...

journal_title：Alimentary pharmacology & therapeutics

authors： Tsai WL,Cheng JS,Lai KH,Lin CP,Lo GH,Hsu PI,Yu HC,Lin CK,Chan HH,Chen WC,Chen TA,Li WL,Liang HL

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:The hepatic venous pressure gradient (HVPG) is an invasive, but important diagnostic and prognostic marker in cirrhosis with portal hypertension (PHT). During cirrhosis, remodelling of fibrotic tissue by matrix metalloproteinases (MMPs) is a permanent process generating small fragments of degraded extracellu...

journal_title：Alimentary pharmacology & therapeutics

authors： Leeming DJ,Karsdal MA,Byrjalsen I,Bendtsen F,Trebicka J,Nielsen MJ,Christiansen C,Møller S,Krag A

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:The presence of the gastric pathogen, Helicobacter pylori influences acid suppression by proton pump inhibitors and treatment outcome in patients with gastro-oesophageal reflux disease. AIM:To determine the influence of H. pylori infection on effectiveness of rabeprazole in primary and secondary care patien...

journal_title：Alimentary pharmacology & therapeutics

authors： Wit NJ,Boer WA,Geldof H,Hazelhoff B,Bergmans P,Tytgat GN,Smout AJ

更新日期：2004-08-15 00:00:00

abstract：BACKGROUND:Patients with chronic hepatitis B (CHB) need long-term antiviral treatment with nucleos(t)ide analogues (NA). Animal studies suggest that some NA may increase cancer risk, but human data are lacking. AIM:To investigate cancer risks in patients with or without NA treatment. METHODS:We conducted a territory-...

journal_title：Alimentary pharmacology & therapeutics

authors： Wong GL,Tse YK,Yip TC,Chan HL,Tsoi KK,Wong VW

更新日期：2017-05-01 00:00:00

abstract：:In the era of expanding medical therapy for ulcerative colitis, surgery is still a very valid option in those patients, where medicine is not able to control symptoms, both in the acute and chronic stages, and also for those at risk of developing a cancer. The ileal pouch-anal anastomosis (IPAA) will, for the vast maj...

journal_title：Alimentary pharmacology & therapeutics

authors： Oresland T

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND:Helicobacter has been identified in isolated cases of hepato-biliary diseases, but its role in the pathogenesis of these conditions remains unclear. AIM:To determine whether Helicobacter could be detected in bile obtained at endoscopic retrograde cholangiopancreatography, and to evaluate the prevalence of t...

journal_title：Alimentary pharmacology & therapeutics

authors： Fallone CA,Tran S,Semret M,Discepola F,Behr M,Barkun AN

更新日期：2003-02-01 00:00:00

abstract：BACKGROUND:Non-alcoholic fatty liver disease (NAFLD) is associated with colorectal neoplasia. Yet, NAFLD ranges from simple steatosis to steatohepatitis with advanced fibrosis. AIM:To investigate the risk of colorectal neoplasia according to the presence and severity of NAFLD. METHODS:A total of 26 540 asymptomatic a...

journal_title：Alimentary pharmacology & therapeutics

authors： Ahn JS,Sinn DH,Min YW,Hong SN,Kim HS,Jung SH,Gu S,Rhee PL,Paik SW,Son HJ,Gwak GY

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Ingested peanut agglutinin stimulates colonic proliferation in humans. In rats, ingested peanut agglutinin stimulates hormone release and proliferation in the small and large intestines. Peanut agglutinin is absorbed into the circulation but little is known about the systemic effect of this lectin. Therefore...

journal_title：Alimentary pharmacology & therapeutics

authors： Jordinson M,Fitzgerald AJ,Goodlad RA,Brynes A,Grant G,Pignatelli M,Calam J

更新日期：2000-06-01 00:00:00

abstract：BACKGROUND:Budd-Chiari syndrome (BCS) is a rare but fatal disease caused by obstruction in the hepatic venous outflow tract. AIM:To provide an update of the pathophysiology, aetiology, diagnosis, management and follow-up of BCS. METHODS:Analysis of recent literature by using Medline, PubMed and EMBASE databases. RES...

journal_title：Alimentary pharmacology & therapeutics

authors： Khan F,Armstrong MJ,Mehrzad H,Chen F,Neil D,Brown R,Cain O,Tripathi D

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Steroid-refractory ulcerative colitis (UC) remains a challenging condition warranting surgery upon failure of pharmacological treatment. Calcineurin inhibitors or infliximab are alternatives in this situation. Data on the efficacy and safety of tacrolimus in this setting are limited. AIM:To study the short-...

journal_title：Alimentary pharmacology & therapeutics

authors： Schmidt KJ,Herrlinger KR,Emmrich J,Barthel D,Koc H,Lehnert H,Stange EF,Fellermann K,Büning J

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:The association between ulcerative colitis and cytomegalovirus (CMV) has been recognised for over 50 years; and the role of CMV in ulcerative colitis in general, and steroid resistance in particular, remains a topic of ongoing controversy. The outcome for patients with CMV reactivation appears worse than tha...

journal_title：Alimentary pharmacology & therapeutics

authors： Sager K,Alam S,Bond A,Chinnappan L,Probert CS

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:The nonselective 5-HT(4) receptor agonists, cisapride and tegaserod have been associated with cardiovascular adverse events (AEs). AIM:To perform a systematic review of the safety profile, particularly cardiovascular, of 5-HT(4) agonists developed for gastrointestinal disorders, and a nonsystematic summary ...

journal_title：Alimentary pharmacology & therapeutics

authors： Tack J,Camilleri M,Chang L,Chey WD,Galligan JJ,Lacy BE,Müller-Lissner S,Quigley EM,Schuurkes J,De Maeyer JH,Stanghellini V

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative pathogen of coronavirus disease 2019 (COVID-19), became a global threat to human health. Liver impairment has been frequently reported as a common manifestation, although its clinical significance is still unclear, particularly in pa...

journal_title：Alimentary pharmacology & therapeutics

authors： Garrido I,Liberal R,Macedo G

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Little is known about the distinctive characteristics of subjects with frequent (at least weekly) and occasional gastro-oesophageal reflux symptoms. AIM:To compare the characteristics and disease management of subjects complaining of at least weekly and less frequent gastro-oesophageal reflux symptoms. MET...

journal_title：Alimentary pharmacology & therapeutics

authors： Bretagne JF,Honnorat C,Richard-Molard B,Caekaert A,Barthélemy P

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:Erythromycin is a potent stimulator of gastrointestinal motility. Recent studies have examined the use of intravenous erythromycin to clear the stomach of blood before oesophago-gastroduodenoscopy (EGD) for acute upper gastrointestinal haemorrhage (UGIH). These studies have shown clinical effectiveness. AIM...

journal_title：Alimentary pharmacology & therapeutics

authors： Winstead NS,Wilcox CM

更新日期：2007-11-15 00:00:00

abstract：:Corticosteroids are highly effective in inducing clinical remission in patients with active Crohn's disease. However, the role of corticosteroids in the treatment of this disease is primarily ameliorative because they are ineffective in maintaining remission or healing mucosal lesions. Nearly half of the patients who ...

journal_title：Alimentary pharmacology & therapeutics

authors： Rutgeerts PJ

更新日期：2001-10-01 00:00:00

abstract：BACKGROUND:Cannabinoid (CB) receptors have been located in brain areas involved in the triggering of TLESRs as well as in the nodose ganglion from which vagal afferents emanate. The distribution of CB(1) receptors has been investigated in the human gastrointestinal mucosa, as expression of inflammatory process. AIM:To...

journal_title：Alimentary pharmacology & therapeutics

authors： Calabrese C,Spisni E,Liguori G,Lazzarini G,Valerii MC,Strillacci A,Gionchetti P,Pagotto U,Campieri M,Rizzello F

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:Mild impairments of cognition or 'Brain fog' are often reported by patients with coeliac disease but the nature of these impairments has not been systematically investigated. AIM:This longitudinal pilot study investigated relationships between cognitive function and mucosal healing in people with newly diag...

journal_title：Alimentary pharmacology & therapeutics

authors： Lichtwark IT,Newnham ED,Robinson SR,Shepherd SJ,Hosking P,Gibson PR,Yelland GW

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:The long-term time trends of multiple gastrointestinal diseases are characterised by a striking rise and fall. These temporal changes provide important clues about disease aetiology. AIM:To highlight the importance of Helicobacter pylori infection in shaping the temporal trends of many common gastrointestin...

journal_title：Alimentary pharmacology & therapeutics

authors： Sonnenberg A

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:The incidence of irritable bowel syndrome is uncertain. We aimed to determine the incidence of clinically diagnosed irritable bowel syndrome in the community. METHODS:Using the Rochester Epidemiology Project, all diagnoses of irritable bowel syndrome made among adult residents of Olmsted County, Minnesota, ...

journal_title：Alimentary pharmacology & therapeutics

authors： Locke GR 3rd,Yawn BP,Wollan PC,Melton LJ 3rd,Lydick E,Talley NJ

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND:Deregulation of mammalian target of rapamycin (mTOR) signalling is common in human hepatocellular carcinoma (HCC). AIM:To determine the maximum tolerated dose (MTD) of the oral mTOR inhibitor everolimus in advanced HCC patients. METHODS:Patients with locally advanced or metastatic HCC (Child-Pugh class A o...

journal_title：Alimentary pharmacology & therapeutics

authors： Shiah HS,Chen CY,Dai CY,Hsiao CF,Lin YJ,Su WC,Chang JY,Whang-Peng J,Lin PW,Huang JD,Chen LT

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Vasoactive medications such as vasopressin, somatostatin and their analogues (terlipressin, vapreotide and octreotide) are commonly used for the treatment of acute variceal bleeding. However, the risks and benefits of these interventions are not well understood. AIM:To undertake a meta-analysis of the effic...

journal_title：Alimentary pharmacology & therapeutics

authors： Wells M,Chande N,Adams P,Beaton M,Levstik M,Boyce E,Mrkobrada M

更新日期：2012-06-01 00:00:00

abstract：AIM:To assess the decline in Helicobacter pylori antibodies after eradication of infection. METHODS:The H. pylori status was determined at entry (D0) by culture and histology performed on antral biopsies and after eradication treatment at day 42 (day 42) and after 6 months (M6) by the 13C-urea breath test. The EIA kit...

journal_title：Alimentary pharmacology & therapeutics

authors： Bergey B,Marchildon P,Peacock J,Mégraud F

更新日期：2003-09-15 00:00:00

abstract：BACKGROUND:Intrahepatic non-hypervascular hypointense nodules (NHHNs) detected during the hepatobiliary phase of gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid-enhanced magnetic resonance imaging (EOB-MRI) have the potential to transition into typical hypervascular hepatocellular carcinoma (HCC). However, ...

journal_title：Alimentary pharmacology & therapeutics

authors： Toyoda H,Tada T,Yasuda S,Mizuno K,Sone Y,Kaneoka Y,Maeda A,Akita T,Tanaka J,Kumada T

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Epidemiological data concerning hepatitis B are scarce in France. AIM:To describe epidemiological, clinical, virological and histological features of HBsAg-positive patients followed at non-academic hospitals in France. METHODS:Clinical, biological, virological and histological data of all HBsAg-positive c...

journal_title：Alimentary pharmacology & therapeutics

authors： Cadranel JF,Lahmek P,Causse X,Bellaiche G,Bettan L,Fontanges T,Medini A,Henrion J,Chousterman M,Condat B,Hervio P,Periac P,Eugène C,Moindrot H,Grasset D,Nouel O,Pilette C,Szostak-Talbodec N,Cayla JM,Si-Ahmed SN,Du

更新日期：2007-08-15 00:00:00

abstract：BACKGROUND:Small bowel bacterial overgrowth is common in Crohn's disease but its treatment is not clearly defined. Metronidazole and ciprofloxacin are effective antibiotics in active Crohn's disease. AIM:To investigate the efficacy of metronidazole and ciprofloxacin in the treatment of bacterial overgrowth in patients...

journal_title：Alimentary pharmacology & therapeutics

authors： Castiglione F,Rispo A,Di Girolamo E,Cozzolino A,Manguso F,Grassia R,Mazzacca G

更新日期：2003-12-01 00:00:00

abstract：BACKGROUND:A variety of tests have been proposed for colorectal cancer (CRC), giving rise to uncertainty regarding the optimal approach. The efficacy and effectiveness of different tests are related to both screened participation and the detection rate. AIM:To perform a meta-analysis on adherence and detection rates o...

journal_title：Alimentary pharmacology & therapeutics

authors： Hassan C,Giorgi Rossi P,Camilloni L,Rex DK,Jimenez-Cendales B,Ferroni E,Borgia P,Zullo A,Guasticchi G,HTA Group.

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:None of the proposed materials tested for the management of perianal fistulae has proven to be a definitive treatment. AIM:To assess a new repair scaffold and drug delivery device conceived to target perianal fistula repair. METHODS:Poly(D,L-lactide-co-glycolide) porous microspheres containing either antib...

journal_title：Alimentary pharmacology & therapeutics

authors： Blaker JJ,Pratten J,Ready D,Knowles JC,Forbes A,Day RM

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:Risk benefit strategies in managing inflammatory bowel diseases (IBD) are dependent upon understanding the risks of uncontrolled inflammation vs those of treatments. Malignancy and mortality in IBD have been associated with disease-related inflammation and immune suppression, but data are limited due to thei...

journal_title：Alimentary pharmacology & therapeutics

authors： Joosse ME,Aardoom MA,Kemos P,Turner D,Wilson DC,Koletzko S,Martin-de-Carpi J,Fagerberg UL,Spray C,Tzivinikos C,Sladek M,Shaoul R,Roma-Giannikou E,Bronsky J,Serban DE,Ruemmele FM,Garnier-Lengline H,Veres G,Hojsak I,K

更新日期：2018-09-01 00:00:00