Systemic effect of peanut agglutinin following intravenous infusion into rats.

abstract：BACKGROUND:Both simple proportions and statistical tests are utilised for symptom-reflux association. We systematically compared three such tests in a clinical setting. AIM:To compare the three commonly used symptom reflux association tests in a large cohort of patients undergoing ambulatory pH monitoring for the eval...

journal_title：Alimentary pharmacology & therapeutics

authors： Kushnir VM,Sathyamurthy A,Drapekin J,Gaddam S,Sayuk GS,Gyawali CP

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Triple therapy currently forms the cornerstone of the treatment of patients with Helicobacter pylori-positive duodenal ulcer. AIM:To establish whether prolonged antisecretory therapy is necessary in patients with active duodenal ulcer. METHODS:A total of 77 patients with H. pylori-positive duodenal ulcer w...

journal_title：Alimentary pharmacology & therapeutics

authors： Tepes B,Krizman I,Gorensek M,Gubina M,Orel I

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND:Crohn's disease (CD) has a high-risk of bowel resection and later surgery for recurrent disease. Recent guidelines recommend colonoscopy 6-12 months following surgery to reduce further surgical intervention through medical therapy intensification. AIMS:To investigate the risk of further surgery at the anast...

journal_title：Alimentary pharmacology & therapeutics

authors： King D,Coupland B,Dosanjh A,Cole A,Adderley NJ,Reulen RC,Patel P,Trudgill NJ

更新日期：2021-01-01 00:00:00

abstract：AIM:To compare endoscopic banding ligation vs. no treatment in cirrhotics with intolerance or contraindications to beta-blockers for prevention of first bleeding in portal hypertension. METHODS:A sample size of 214 was planned with all sizes of varices. However, the trial was stopped due to increased bleeding in 52 pa...

journal_title：Alimentary pharmacology & therapeutics

authors： Triantos C,Vlachogiannakos J,Armonis A,Saveriadis A,Kougioumtzian A,Leandro G,Manolakopoulos S,Tzourmakliotis D,Raptis SA,Burroughs AK,Avgerinos A

更新日期：2005-06-15 00:00:00

abstract：BACKGROUND:The incidence of Barrett's oesophageal adenocarcinoma is increasing more rapidly than any other malignancy in industrialized countries. Cyclo-oxygenase-2 appears to play an important role in gastrointestinal carcinogenesis. Previous studies on cyclo-oxygenase-2 expression in Barrett's oesophageal carcinogene...

journal_title：Alimentary pharmacology & therapeutics

authors： Cheong E,Igali L,Harvey I,Mole M,Lund E,Johnson IT,Rhodes M

更新日期：2003-02-01 00:00:00

abstract：BACKGROUND:The diagnosis of covert hepatic encephalopathy (CHE) by means of portosystemic encephalopathy syndrome (PSE) test is costly and therefore infrequently performed. AIM:To determine the ability of critical flicker frequency (CFF) alone or in combination with laboratory findings, as an initial test to pre-selec...

journal_title：Alimentary pharmacology & therapeutics

authors： Greinert R,Ripoll C,Hollenbach M,Zipprich A

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:It is not clear whether the incidence or early mortality related to peptic ulcer perforation has changed. AIM:To evaluate the incidence and mortality related to peptic ulcer perforation while considering the intake of low-dose aspirin and nonsteroidal anti-inflammatory drugs (NSAIDs). METHODS:We recorded t...

journal_title：Alimentary pharmacology & therapeutics

authors： Taha AS,Angerson WJ,Prasad R,McCloskey C,Gilmour D,Morran CG

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND:CXC chemokines such as interleukin (IL)-8 are neutrophil chemoattractants, the levels of which increase in Helicobacter pylori-infected gastric mucosa. Many investigators have focused on the chemotactic aspects of IL-8: however, CXC chemokines are also reported to have angiogenic activity and to serve as rem...

journal_title：Alimentary pharmacology & therapeutics

authors： Suzuki H,Mori M,Seto K,Shibata F,Nagahashi S,Kawaguchi C,Suzuki M,Matsui H,Watanabe K,Miura S,Ishii H

更新日期：2000-04-01 00:00:00

abstract：BACKGROUND:Intravenous octreotide is an established treatment of oesophageal variceal haemorrhage in the cirrhotic patient. AIM:To examine the organ extraction and splanchnic haemodynamic effects of octreotide in cirrhotic patients with portal hypertension. METHODS:Thirteen patients with cirrhosis had hepatic venous ...

journal_title：Alimentary pharmacology & therapeutics

authors： Ottesen LH,Flyvbjerg A,Møller S,Bendtsen F

更新日期：1998-07-01 00:00:00

abstract：BACKGROUND:More convenient therapies are needed to treat Helicobacter pylori infection successfully. Clarithromycin and amoxycillin are effective against H. pylori both in vivo and in vitro. Recent success with a high dose amoxycillin-metronidazole combination therapy led us to evaluate clarithromycin-amoxycillin dual ...

journal_title：Alimentary pharmacology & therapeutics

authors： al-Assi MT,Genta RM,Karttunen TJ,Graham DY

更新日期：1994-08-01 00:00:00

abstract：BACKGROUND:Non-ulcer dyspepsia is predominantly a self-managed condition, although it accounts for a significant number of general practitioner consultations and hospital referrals. Herbal medicinal products are often used for the relief of dyspeptic symptoms. AIMS:: To critically assess the evidence for and against h...

journal_title：Alimentary pharmacology & therapeutics

authors： Thompson Coon J,Ernst E

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND:Faecal calprotectin is a reliable tool for predicting Crohn's disease (CD) relapse in patients with sustained remission. Prediction of relapse with faecal calprotectin has been less studied in patients with severe CD treated with anti-TNF. AIM:To identify an association between faecal calprotectin concentra...

journal_title：Alimentary pharmacology & therapeutics

authors： Laharie D,Mesli S,El Hajbi F,Chabrun E,Chanteloup E,Capdepont M,Razaire S,de Lédinghen V,Zerbib F

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:No prognostic tools are established for alcohol-related liver disease (ALD). Collagen proportionate area (CPA) measurement is a technique that quantifies fibrous tissue in liver biopsies using digital image analysis. AIM:To assess the predictive value of CPA on hepatic decompensation and liver-related morta...

journal_title：Alimentary pharmacology & therapeutics

authors： Israelsen M,Guerrero Misas M,Koutsoumourakis A,Huang Y,Thiele M,Hall A,Rasmussen D,Covelli C,Buzzetti E,Prat LI,Roccarina D,Detlefsen S,Luong TV,Quaglia A,Krag A,Jeffrey G,Pinzani M,Tsochatzis EA

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Occult biliary stones escape detection on conventional investigations, and clinico-biochemical systems proposed for predicting biliary pancreatitis has low predictive values. AIM:To evaluate the accuracy of clinico-biochemical parameters for prediction of biliary pancreatitis in patients undergoing endoscop...

journal_title：Alimentary pharmacology & therapeutics

authors： Liu CL,Fan ST,Lo CM,Tso WK,Wong Y,Poon RT,Lam CM,Wong BC,Wong J

更新日期：2005-09-01 00:00:00

abstract：:The goals of the Baveno workshops were to develop consensus definitions of key events related to portal hypertension and variceal bleeding, and to produce guidelines to facilitate the conduct and reporting of clinical trials. The consensus definitions concern the diagnosis of active bleeding, failure to control bleedi...

journal_title：Alimentary pharmacology & therapeutics

authors： de Franchis R

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND:Helicobacter pylori is one of the most prevalent global pathogens and can lead to gastrointestinal disease including peptic ulcers, gastric marginal zone lymphoma and gastric carcinoma. AIM:To review recent trends in H. pylori antibiotic resistance rates, and to discuss diagnostics and treatment paradigms. ...

journal_title：Alimentary pharmacology & therapeutics

authors： Thung I,Aramin H,Vavinskaya V,Gupta S,Park JY,Crowe SE,Valasek MA

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Patients with inflammatory bowel disease (IBD) are at increased risk of osteoporosis. A number of studies have emerged in recent years indicating that tumour necrosis factor (TNF) blockade appears to have a beneficial effect on bone mineral density (BMD) in IBD patients. AIMS:To provide a review of the avai...

journal_title：Alimentary pharmacology & therapeutics

authors： Veerappan SG,O'Morain CA,Daly JS,Ryan BM

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:Gastroparesis is a chronic disorder caused by stomach pump failure and characterized by profound nausea, vomiting and epigastric pain. Most often, the cause is unapparent and of the known associations, diabetes is the most common. Diagnosis is usually made using an isotope-labelled test meal. Treatment is in...

journal_title：Alimentary pharmacology & therapeutics

authors： Patrick A,Epstein O

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:Fibroblast growth factors play an important role in (patho)physiological processes such as wound healing and tissue repair. We previously showed that basic fibroblast growth factor is actively involved in inflammatory bowel disease processes. In the present retrospective study, we assessed whether serum basi...

journal_title：Alimentary pharmacology & therapeutics

authors： Gao Q,Hogezand RA,Lamers CB,Verspaget HW

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND:The approval of the tyrosine kinase inhibitor sorafenib in 2007 marked a milestone in the treatment of hepatocellular carcinoma, as sorafenib was the first systemic therapy to show a survival benefit in patients with advanced hepatocellular carcinoma. Since then many drugs failed in the first- and second-lin...

journal_title：Alimentary pharmacology & therapeutics

authors： Pinter M,Peck-Radosavljevic M

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:Factors associated with mortality and disease progression in non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) are poorly understood. AIMS:To assess the impact of liver disease severity, demographics and comorbidities on all-cause mortality and liver disease progression in a...

journal_title：Alimentary pharmacology & therapeutics

authors： Canbay A,Kachru N,Haas JS,Sowa JP,Meise D,Ozbay AB

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:Gastro-oesophageal reflux is thought to cause chronic laryngitis through laryngopharyngeal reflux. Response of laryngitis to treatment with acid-suppressive therapy supports this causal link. AIM:To determine the prevalence of gastro-oesophageal reflux disease in patients with chronic laryngitis and respons...

journal_title：Alimentary pharmacology & therapeutics

authors： Qua CS,Wong CH,Gopala K,Goh KL

更新日期：2007-02-01 00:00:00

abstract：:In a double-blind crossover study, lower oesophageal sphincter pressure (LOSP) and distal oesophageal motility were studied in eight healthy volunteers following a single intravenous dose of omeprazole or placebo. Lower oesophageal sphincter pressure was determined before and at intervals up to 120 min after intraveno...

journal_title：Alimentary pharmacology & therapeutics

authors： Chakraborty TK,De Caestecker JS,Pryde A,Heading RC

更新日期：1987-12-01 00:00:00

abstract：BACKGROUND:Pregabalin has a broad spectrum of analgesic and antihyperalgesic activity in both basic and clinical studies. However, its mechanisms and sites of action have yet to be determined in humans. AIMS:To assess the antinociceptive effect of pregabalin on experimental gut pain in patients with visceral hyperalge...

journal_title：Alimentary pharmacology & therapeutics

authors： Olesen SS,Graversen C,Olesen AE,Frøkjaer JB,Wilder-Smith O,van Goor H,Valeriani M,Drewes AM

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Optimal management approach is not well defined for subjects who fail initial first- and second-line Helicobacter pylori eradication attempts and are dealt on a case-by-case basis by the specialists. AIM:To evaluate the efficacy and safety of standard and 'rescue' eradication therapies at primary and second...

journal_title：Alimentary pharmacology & therapeutics

authors： Qasim A,Sebastian S,Thornton O,Dobson M,McLoughlin R,Buckley M,O'Connor H,O'Morain C

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:There is no consensus on the standard treatment of gastric mucosa-associated lymphoid tissue (MALT) lymphoma for Helicobacter pylori-negative patients and for patients with persistent disease despite H. pylori eradication. AIM:To evaluate the comparative efficacy and safety of alkylating agents and rituxima...

journal_title：Alimentary pharmacology & therapeutics

authors： Amiot A,Lévy M,Copie-Bergman C,Dupuis J,Szablewski V,Le Baleur Y,Baia M,Belhadj K,Sobhani I,Leroy K,Haioun C,Delchier JC

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:There is expanding interest in the role that diet plays in ileoanal pouch function and in the pathogenesis of pouchitis. AIMS:To present a narrative review of published literature regarding the relationship of diet with pouch function and the pathogenesis of pouchitis, and to provide potentially beneficial ...

journal_title：Alimentary pharmacology & therapeutics

authors： Ardalan ZS,Yao CK,Sparrow MP,Gibson PR

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:Endocytoscopy (EC) enables in vivo microscopic imaging at 1400-fold magnification, thereby allowing the analysis of mucosal structures at the cellular level. In contrast to fluorescence imaging with confocal laser endomicroscopy which allows analysis of mucosal structures up to 250 μm in depth, EC is based o...

journal_title：Alimentary pharmacology & therapeutics

authors： Neumann H,Fuchs FS,Vieth M,Atreya R,Siebler J,Kiesslich R,Neurath MF

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:Haemorrhage from ruptured oesophageal varices is a common cause of death in people with cirrhosis. Guidelines recommend screening for varices at time of cirrhosis diagnosis and throughout the course of the disease. Conventional gastroscopy is the criterion standard for variceal screening; however, is invasiv...

journal_title：Alimentary pharmacology & therapeutics

authors： Wickremeratne T,Turner S,O'Beirne J

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:Crohn's disease (CD) and ulcerative colitis (UC) are chronic inflammatory diseases of the intestine, which frequently require surgery for complications or failure of medical therapy. AIM:To seek evidence and provide direction for clinicians on optimal strategies to enable steroid free remission in inflammat...

journal_title：Alimentary pharmacology & therapeutics

authors： Panaccione R,Rutgeerts P,Sandborn WJ,Feagan B,Schreiber S,Ghosh S

更新日期：2008-09-15 00:00:00