Systematic review: herbal medicinal products for non-ulcer dyspepsia.

abstract：AIM:To compare the antisecretory effects of rabeprazole and esomeprazole in an open, randomized, two-way crossover, clinical pharmacology study. METHODS:Twenty-four healthy subjects (14 men, 10 women; mean age 26.8 years) received rabeprazole 20 mg or esomeprazole 20 mg daily on days 1-5, with a 14-day 'wash-out'. Int...

journal_title：Alimentary pharmacology & therapeutics

authors： Warrington S,Baisley K,Boyce M,Tejura B,Morocutti A,Miller N

更新日期：2002-07-01 00:00:00

abstract：BACKGROUND:Real-life long-term data on infliximab treatment in ulcerative colitis are limited. AIM:To study the long-term efficacy and safety of infliximab in chronic active ulcerative colitis and possible predictors of colectomy and response were also examined. METHODS:A retrospective multi-centre study of inflixima...

journal_title：Alimentary pharmacology & therapeutics

authors： Angelison L,Almer S,Eriksson A,Karling P,Fagerberg U,Halfvarson J,Thörn M,Björk J,Hindorf U,Löfberg R,Bajor A,Hjortswang H,Hammarlund P,Grip O,Torp J,Marsal J,Hertervig E,Swedish Organization for the Study of Inflammato

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:Antibiotic resistance has increasingly been recognized as the major cause of treatment failure for Helicobacter pylori infection. New therapies for patients with metronidazole- or clarithromycin-resistant H. pylori are needed. AIM:To investigate the role of nitrofurantoin quadruple therapy for the treatment...

journal_title：Alimentary pharmacology & therapeutics

authors： Graham DY,Saeed MA,Hoffman J,El-Zimaity HM,Kwon DH,Osato MS

更新日期：2001-04-01 00:00:00

abstract：BACKGROUND:A short-term course of pegylated-interferon (Peg-IFN), or a long-term treatment with a third generation nucleot(s)ide analogue (NUC), of chronic hepatitis B (CHB) infection achieves viral suppression and may prevent disease progression. Owing to different mechanisms of action of the two regimens, a Peg-IFN a...

journal_title：Alimentary pharmacology & therapeutics

authors： Viganò M,Invernizzi F,Grossi G,Lampertico P

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:In spite of its frequent use in the treatment of irritable bowel disease little is known about mebeverine's mode of action in man. AIM:To examine mebeverine's effect on transit though the gut during lactulose-induced diarrhoea. METHODS:Nine healthy volunteers undertook a two-way randomized crossover study....

journal_title：Alimentary pharmacology & therapeutics

authors： Washington N,Ridley P,Thomas C,Spiller RC,Watts PJ,Wilson CG

更新日期：1998-06-01 00:00:00

abstract：:The efficacy of a nitroimidazole-containing regimen for the treatment of Helicobacter pylori infection is decreased by nitroimidazole resistance. Nitroimidazoles are meta- bolized by H. pylori by several nitro-reductases of which an oxygen-insensitive NADPH nitroreductase encoded by the rdxA gene is the most important...

journal_title：Alimentary pharmacology & therapeutics

authors： Van Der Wouden EJ,Thijs JC,Van Zwet AA,Kleibeuker JH

更新日期：2000-01-01 00:00:00

abstract：:Helicobacter pylori produces a 550 kDa, multimeric, nickel-containing urease that catalyses the hydrolysis of urea to yield ammonia and carbonic acid. The ure gene cluster, comprised of seven genes, encodes the two structural subunits UreA (26.5 kDa) and UreB (60.3 kDa), and five accessory proteins: UreI, UreE, UreF, ...

journal_title：Alimentary pharmacology & therapeutics

authors： Mobley HL

更新日期：1996-04-01 00:00:00

abstract：:The effect of ephedrine, a non-selective adrenoreceptor agonist, and yohimbine, a selective alpha 2-adrenolytic drug, on gastric emptying of a radiolabelled solid meal was examined in groups of 8 (all women) and 15 (4 men and 11 women) obese patients, respectively. Patients were given orally, double-blind in random or...

journal_title：Alimentary pharmacology & therapeutics

authors： Jonderko K,Kucio C

更新日期：1991-08-01 00:00:00

abstract：BACKGROUND:Proton pump inhibitors including omeprazole and lansoprazole inhibit gastric acid secretion by selectively and non-competitively inactivating the H+, K+ ATPase molecules of the parietal cell, but possibly only those that are actively secreting acid. This might imply that stimulation of acid secretion by a me...

journal_title：Alimentary pharmacology & therapeutics

authors： Hatlebakk JG,Katz PO,Camacho-Lobato L,Castell DO

更新日期：2000-10-01 00:00:00

abstract：BACKGROUND:Ursodeoxycholic acid (UDCA) prolongs transplantation-free survival in primary biliary cirrhosis (PBC). However, the optimal therapeutic dose has not been established. AIM:To compare the effects of UDCA administered in daily doses of 10 vs. 20 mg/kg on symptoms, liver biochemistry and biliary UDCA enrichment...

journal_title：Alimentary pharmacology & therapeutics

authors： Van Hoogstraten HJ,De Smet MB,Renooij W,Breed JG,Engels LG,Den Ouden-Muller JW,Rijk MC,Smit AM,Zwertbroek R,Hop WC,van Berge Henegouwen GP,Schalm SW,van Buuren HR

更新日期：1998-10-01 00:00:00

abstract：BACKGROUND:Therapeutic options for achalasia include pharmacological therapy, surgical myotomy, pneumatic dilatation and intrasphincteric botulinum toxin injection. AIM:To compare botulinum toxin injection with pneumatic dilatation in a randomized trial. PATIENTS/METHODS:Forty adults with newly diagnosed achalasia we...

journal_title：Alimentary pharmacology & therapeutics

authors： Mikaeli J,Fazel A,Montazeri G,Yaghoobi M,Malekzadeh R

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND:Direct-acting antiviral (DAA) regimens have shown high efficacy and tolerability for patients with HCV genotype 1/1b (GT1/1b) in clinical trials. However, robust real-world evidence of interferon (IFN)-free DAA treatment for HCV GT1-infected patients in Asia is still lacking. AIM:To systematically review an...

journal_title：Alimentary pharmacology & therapeutics

authors： Ji F,Wei B,Yeo YH,Ogawa E,Zou B,Stave CD,Li Z,Dang S,Furusyo N,Cheung RC,Nguyen MH

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Twice-daily dosing is increasingly used to improve gastric acid control, although not all proton-pump inhibitors are more effective when doses are split. Standard dose esomeprazole provides better gastric acid control than other standard dose proton-pump inhibitors. AIMS:To compare the effect of standard do...

journal_title：Alimentary pharmacology & therapeutics

authors： Hammer J,Schmidt B

更新日期：2004-05-15 00:00:00

abstract：BACKGROUND:The Gut and Obesity Asia (GO ASIA) workgroup was formed to study the relationships between obesity and gastrointestinal diseases in the Asia Pacific region. AIM:To study factors associated with nonalcoholic steatohepatitis (NASH) and advanced fibrosis, and medical treatment of biopsy-proven nonalcoholic fat...

journal_title：Alimentary pharmacology & therapeutics

authors： Chan WK,Treeprasertsuk S,Imajo K,Nakajima A,Seki Y,Kasama K,Kakizaki S,Fan JG,Song MJ,Yoon SK,Dan YY,Lesmana L,Ho KY,Goh KL,Wong VW

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Fistulae will develop in approximately one-third of patients with Crohn's disease. With an expected spontaneous healing rate of only 10%, fistulizing Crohn's disease requires a comprehensive strategy with a medical and possible surgical approach. AIM:To summarize the current literature evaluating various me...

journal_title：Alimentary pharmacology & therapeutics

authors： Bressler B,Sands BE

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:Recently, a rapid-release 100-mg 13C-urea tablet with citrate supplement (Diabact UBT) showed excellent performance in a European population. AIM:To investigate the accuracy of a 50-mg tablet-based 13C-urea breath test protocol. METHODS:: Consecutive dyspeptic patients referred for upper endoscopy were rec...

journal_title：Alimentary pharmacology & therapeutics

authors： Wong WM,Lam SK,Lai KC,Chu KM,Xia HH,Wong KW,Cheung KL,Lin SK,Wong BC

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:The efficacy of each probiotic should be evaluated separately. Previously, we have shown that Lactobacillus GG (LGG) is effective in treating acute gastroenteritis (AGE) in children. AIM:To update our 2007 meta-analysis on the effectiveness of LGG in treating AGE in children. METHODS:The Cochrane Library, ...

journal_title：Alimentary pharmacology & therapeutics

authors： Szajewska H,Skórka A,Ruszczyński M,Gieruszczak-Białek D

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Dramatic changes in the prevalence and pattern of gastrointestinal disease has taken place in Asia in recent years. AIM:To compare the prevalence of duodenal (DU) and gastric ulcers (GU), erosive oesophagitis (EO), gastric cancer (GCA) and oesophageal cancer (OCA) and Helicobacter pylori infection over a 10...

journal_title：Alimentary pharmacology & therapeutics

authors： Goh KL,Wong HT,Lim CH,Rosaida MS

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:The presenting symptoms of coeliac disease are often subtle and the diagnosis is frequently delayed or overlooked. Therefore, especially elderly patients may be denied the benefits conferred by gluten free diet which can be dramatically life-changing. AIM:To review the occurrence, clinical features, diagnos...

journal_title：Alimentary pharmacology & therapeutics

authors： Collin P,Vilppula A,Luostarinen L,Holmes GKT,Kaukinen K

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:In patients with idiopathic non-cirrhotic portal hypertension (INCPH), the usual recommended strategy for management of variceal bleeding is the same as that in cirrhosis. However, this policy has been challenged by the different natural history between INCPH and cirrhosis. AIM:To compare outcomes after tra...

journal_title：Alimentary pharmacology & therapeutics

authors： Lv Y,Li K,He C,Luo B,Zhang B,Liu H,Wang Z,Guo W,Wang Q,Chen H,Bai W,Yuan X,Yu T,Li X,Yuan J,Han N,Zhu Y,Niu J,Xie H,Wang J,Chen L,Yin Z,Fan D,Li Z,Han G

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Patient-reported outcome (PRO) measures historically used in inflammatory bowel disease have been considered inadequate to support future drug labelling claims by regulatory agencies. AIMS:To develop PRO tools for use in Crohn's disease (CD) and ulcerative colitis (UC) following guidance issued by the US FD...

journal_title：Alimentary pharmacology & therapeutics

authors： Dulai PS,Jairath V,Khanna R,Ma C,McCarrier KP,Martin ML,Parker CE,Morris J,Feagan BG,Sandborn WJ

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Although the use of tumour necrosis factor (TNF) antagonists is increasingly codified, several unresolved issues remain. AIM:To conduct a French national survey on TNF antagonists use in inflammatory bowel disease (IBD). METHODS:A postal questionnaire was sent to all French gastroenterologists among whom 4...

journal_title：Alimentary pharmacology & therapeutics

authors： Oussalah A,Roblin X,Laharie D,Filippi J,Flamant M,Faure P,Phelip JM,Bigard MA,Peyrin-Biroulet L

更新日期：2009-10-15 00:00:00

abstract：BACKGROUND:Ingested peanut agglutinin stimulates colonic proliferation in humans. In rats, ingested peanut agglutinin stimulates hormone release and proliferation in the small and large intestines. Peanut agglutinin is absorbed into the circulation but little is known about the systemic effect of this lectin. Therefore...

journal_title：Alimentary pharmacology & therapeutics

authors： Jordinson M,Fitzgerald AJ,Goodlad RA,Brynes A,Grant G,Pignatelli M,Calam J

更新日期：2000-06-01 00:00:00

abstract：:The mode of transmission of Helicobacter pylori is largely unknown and is a matter of circumstantial evidence and speculation rather than fact. However, the principle evidence is of two sorts: the epidemiological data, providing evidence of possible risk factors associated with transmission, and the identification of ...

journal_title：Alimentary pharmacology & therapeutics

authors： Vaira D,Holton J,Ricci C,Menegatti M,Gatta L,Berardi S,Tampieri A,Miglioli M

更新日期：2001-06-01 00:00:00

abstract：BACKGROUND:Drug-induced liver injury may be immunologically mediated or metabolically induced. Peripheral eosinophilia and liver eosinophilia in suspected drug-induced liver injury generally supports the role of drug aetiology. AIM:To assess the importance of eosinophilia and hepatic necrosis on outcome in patients wi...

journal_title：Alimentary pharmacology & therapeutics

authors： Björnsson E,Kalaitzakis E,Olsson R

更新日期：2007-06-15 00:00:00

abstract：:Both duodenal and gastric ulcer disease are closely associated with Helicobacter pylori infection. An infected individual has an estimated lifetime risk of 10-20% for the development of peptic ulcer disease, which is at least 3-4 fold higher than in non-infected subjects. H. pylori infection can be diagnosed in 90-100...

journal_title：Alimentary pharmacology & therapeutics

authors： Kuipers EJ,Thijs JC,Festen HP

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:Oral tacrolimus, approved for the prophylaxis of organ rejection in liver or kidney transplants, has been reported to be effective in anecdotal cases of refractory inflammatory bowel disease. AIM:To evaluate the usefulness of low-dose oral tacrolimus in refractory inflammatory bowel disease. METHODS:Thirty...

journal_title：Alimentary pharmacology & therapeutics

authors： Baumgart DC,Wiedenmann B,Dignass AU

更新日期：2003-05-15 00:00:00

abstract：BACKGROUND:Both simple proportions and statistical tests are utilised for symptom-reflux association. We systematically compared three such tests in a clinical setting. AIM:To compare the three commonly used symptom reflux association tests in a large cohort of patients undergoing ambulatory pH monitoring for the eval...

journal_title：Alimentary pharmacology & therapeutics

authors： Kushnir VM,Sathyamurthy A,Drapekin J,Gaddam S,Sayuk GS,Gyawali CP

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Grey Zone (GZ) is an ill-defined situation including patients falling between inactive carrier (IC) state and HBeAg-negative chronic hepatitis B (HBeAg-negative CHB). AIMS:To assess the long-term outcomes of GZ patients compared to IC in the absence of treatment. METHODS:Retrospective analysis of 287 IC an...

journal_title：Alimentary pharmacology & therapeutics

authors： Bonacci M,Lens S,Mariño Z,Londoño MC,Rodríguez-Tajes S,Mas A,García-López M,Pérez-Del-Pulgar S,Sánchez-Tapias JM,Forns X

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:Cross-sectional imaging techniques, including ultrasonography (US), computed tomography (CT) and magnetic resonance imaging (MRI), are increasingly used for evaluation of Crohn's disease (CD). Aim  To perform an assessment of the diagnostic accuracy of cross-sectional imaging techniques for diagnosis of CD, ...

journal_title：Alimentary pharmacology & therapeutics

authors： Panés J,Bouzas R,Chaparro M,García-Sánchez V,Gisbert JP,Martínez de Guereñu B,Mendoza JL,Paredes JM,Quiroga S,Ripollés T,Rimola J

更新日期：2011-07-01 00:00:00