Review article: in vivo imaging by endocytoscopy.

abstract：BACKGROUND:Dermatitis herpetiformis forms part of the same spectrum of gluten-sensitive disorders as coeliac disease yet may have different risks of morbidity and mortality. AIMS:To quantify the risks of fracture, malignancy and mortality in people with dermatitis herpetiformis compared with the general population. M...

journal_title：Alimentary pharmacology & therapeutics

authors： Lewis NR,Logan RF,Hubbard RB,West J

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:Ulcerative colitis with diverticulosis (UCD), segmental colitis associated with diverticulosis (SCAD) and acute uncomplicated diverticulitis (AUD) may affect the same colonic regions, but the real incidence of these entities in clinical practice is unknown. AIM:To assess the incidence and the endoscopic fin...

journal_title：Alimentary pharmacology & therapeutics

authors： Tursi A,Elisei W,Giorgetti GM,Aiello F,Brandimarte G

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:No validated patient-reported outcome (PRO) measure exists for functional dyspepsia (FD) assessment. Verbal descriptions of different upper abdominal symptoms may be poorly distinguishable to patients. AIM:To investigate whether understanding of FD symptoms is enhanced by pictograms symbolising the nature o...

journal_title：Alimentary pharmacology & therapeutics

authors： Tack J,Carbone F,Holvoet L,Vanheel H,Vanuytsel T,Vandenberghe A

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:Gastrointestinal (GI) symptoms are common in soldiers in combat or high-pressure operational situations and often lead to compromised performance. Underlying mechanisms are unclear, but neuroendocrine dysregulation, immune activation and increased intestinal permeability may be involved in stress-related GI ...

journal_title：Alimentary pharmacology & therapeutics

authors： Li X,Kan EM,Lu J,Cao Y,Wong RK,Keshavarzian A,Wilder-Smith CH

更新日期：2013-04-01 00:00:00

abstract：:Alginate-based raft-forming formulations have been marketed word-wide for over 30 years under various brand names, including Gaviscon. They are used for the symptomatic treatment of heartburn and oesophagitis, and appear to act by a unique mechanism which differs from that of traditional antacids. In the presence of g...

journal_title：Alimentary pharmacology & therapeutics

authors： Mandel KG,Daggy BP,Brodie DA,Jacoby HI

更新日期：2000-06-01 00:00:00

abstract：:The efforts of clinical researchers, lay organizations and pharmaceutical companies have increased the public profile of irritable bowel syndrome and made it a respectable diagnosis. Diagnostic symptom criteria encourage a firm clinical diagnosis, which is the foundation of a logical management strategy. This begins w...

journal_title：Alimentary pharmacology & therapeutics

authors： Thompson WG

更新日期：2002-08-01 00:00:00

abstract：BACKGROUND:In a previous study, the use of a citric acid test meal produced a rapid dose-dependent increase in urease activity that was significantly greater than that resulting from a pudding meal, ascorbic acid or sodium citrate. The mechanism was hypothesized to be related to the ability of citric acid to delay gast...

journal_title：Alimentary pharmacology & therapeutics

authors： Shiotani A,Saeed A,Yamaoka Y,Osato MS,Klein PD,Graham DY

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND:Pneumatic dilation has re-emerged as a first line treatment for achalasia, but conclusions are limited by the relatively small numbers of patients studied and the lack of long term follow-up. AIM:To summarise and analyse 29 available studies evaluating pneumatic dilation for achalasia with focus on efficacy...

journal_title：Alimentary pharmacology & therapeutics

authors： Katzka DA,Castell DO

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Crohn's disease (CD) has a high-risk of bowel resection and later surgery for recurrent disease. Recent guidelines recommend colonoscopy 6-12 months following surgery to reduce further surgical intervention through medical therapy intensification. AIMS:To investigate the risk of further surgery at the anast...

journal_title：Alimentary pharmacology & therapeutics

authors： King D,Coupland B,Dosanjh A,Cole A,Adderley NJ,Reulen RC,Patel P,Trudgill NJ

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Infliximab reduces mucosal inflammation in some, but not all, patients with Crohn's disease. AIM:To monitor clinical data and changes in mucosal cytokine levels after infliximab treatment to identify differences between responders and non-responders. METHODS:Twenty-six patients with fistulating Crohn's dis...

journal_title：Alimentary pharmacology & therapeutics

authors： Agnholt J,Dahlerup JF,Buntzen S,Tøttrup A,Nielsen SL,Lundorf E

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND:Vasoactive medications such as vasopressin, somatostatin and their analogues (terlipressin, vapreotide and octreotide) are commonly used for the treatment of acute variceal bleeding. However, the risks and benefits of these interventions are not well understood. AIM:To undertake a meta-analysis of the effic...

journal_title：Alimentary pharmacology & therapeutics

authors： Wells M,Chande N,Adams P,Beaton M,Levstik M,Boyce E,Mrkobrada M

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Symptoms of lactose intolerance are often attributed to lactose malabsorption but, as this relationship has not been demonstrated when a small dose of lactose similar to that contained in one cup of milk is ingested by intolerant patients, psychological factors may play a role in altered symptom perception. ...

journal_title：Alimentary pharmacology & therapeutics

authors： Tomba C,Baldassarri A,Coletta M,Cesana BM,Basilisco G

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Tacrolimus is a calcineurin inhibitor commonly used for prophylaxis of rejection in renal and liver transplantation. There are limited but favourable data regarding its possible use in patients with inflammatory bowel disease (IBD). AIMS:To evaluate the efficacy and safety of tacrolimus in patients with IBD...

journal_title：Alimentary pharmacology & therapeutics

authors： Rodríguez-Lago I,Castro-Poceiro J,Fernández-Clotet A,Mesonero F,López-Sanromán A,López-García A,Márquez L,Clos-Parals A,Cañete F,Vicuña M,Nantes Ó,Merino O,Matallana V,Gordillo J,Elorza A,Vicente R,Casanova MJ,Ferreiro-

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Coeliac disease (CD), originally thought to be largely confined to Northern Europe and Australasia and uncommon in North America and the Middle East, is now recognised to be equally common in all these countries. It is still thought to be rare in the Orient and Sub-Saharan Africa. AIM:To assess geographical...

journal_title：Alimentary pharmacology & therapeutics

authors： Kang JY,Kang AH,Green A,Gwee KA,Ho KY

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:Increased risk of cardiovascular and cerebrovascular disease in liver transplant recipients results in particular from the side effects of calcineurin inhibitor-based immunosuppressive therapy. Several studies have demonstrated a more favourable outcome for patients receiving tacrolimus (TAC) as compared wit...

journal_title：Alimentary pharmacology & therapeutics

authors： Beckebaum S,Klein C,Varghese J,Sotiropoulos GC,Saner F,Schmitz K,Gerken G,Paul A,Cicinnati VR

更新日期：2009-10-15 00:00:00

abstract：BACKGROUND:Subtotal or total colectomy or proctocolectomy with permanent ileostomy (TC-PI) may be a treatment option for medically refractory colonic Crohn's disease (CD). AIM:To perform a systematic review and meta-analysis to evaluate the rate, risk factors and outcomes of CD recurrence after TC-PI. METHODS:In a sy...

journal_title：Alimentary pharmacology & therapeutics

authors： Fumery M,Dulai PS,Meirick P,Farrell AM,Ramamoorthy S,Sandborn WJ,Singh S

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:Helicobacter pylori eradication is a challenge in patients allergic to penicillin, especially those who have failed a first-eradication trial. AIM:To assess the efficacy and tolerability of H. pylori first-line treatment and rescue options in patients allergic to penicillin. METHODS:Prospective single cent...

journal_title：Alimentary pharmacology & therapeutics

authors： Gisbert JP,Gisbert JL,Marcos S,Olivares D,Pajares JM

更新日期：2005-11-15 00:00:00

abstract：BACKGROUND:Although highly prevalent, little is known about the economic impact of functional dyspepsia (FD). AIMS:To quantify FD patients' health care utilisation patterns and to estimate direct and indirect costs of FD to patients. METHODS:ICD-9 codes identified adult patients with dyspepsia. A validated questionna...

journal_title：Alimentary pharmacology & therapeutics

authors： Lacy BE,Weiser KT,Kennedy AT,Crowell MD,Talley NJ

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Helicobacter pylori infection elicits persistent neutrophil infiltration in gastric mucosa. The expression of cyclooxygenase (COX)-2 and inhibition of apoptosis in the neutrophils could contribute to the pathogenesis of H. pylori infection. Rebamipide, a mucosal protective and ulcer-healing drug, has been kn...

journal_title：Alimentary pharmacology & therapeutics

authors： Kim JS,Kim JM,Jung HC,Song IS

更新日期：2003-07-01 00:00:00

abstract：:Chemotherapy and radiotherapy, whilst highly effective in the treatment of neoplasia, can also cause damage to healthy tissue. In particular, the alimentary tract may be badly affected. Severe inflammation, lesioning and ulceration can occur. Patients may experience intense pain, nausea and gastro-enteritis. They are ...

journal_title：Alimentary pharmacology & therapeutics

authors： Duncan M,Grant G

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:Studies have shown that past alcohol consumption reduces response rates in patients with chronic hepatitis C treated with interferon monotherapy. AIM:To clarify the importance of alcohol consumption on response rates in patients undergoing treatment with pegylated interferon and ribavirin. METHODS:In a sin...

journal_title：Alimentary pharmacology & therapeutics

authors： Chang A,Skole K,Gautam M,Schmutz J,Black M,Thomas R,Horwitz B,Friedenberg FK

更新日期：2005-10-15 00:00:00

abstract：BACKGROUND:The diagnosis of covert hepatic encephalopathy (CHE) by means of portosystemic encephalopathy syndrome (PSE) test is costly and therefore infrequently performed. AIM:To determine the ability of critical flicker frequency (CFF) alone or in combination with laboratory findings, as an initial test to pre-selec...

journal_title：Alimentary pharmacology & therapeutics

authors： Greinert R,Ripoll C,Hollenbach M,Zipprich A

更新日期：2016-09-01 00:00:00

abstract：:In a double-blind, placebo-controlled study of SK&F 94482 (BMY-25368) (400-mg, post-evening meal, for 7 days in 11 healthy subjects), there was a significant 75% decrease in median integrated 24-h intragastric acidity during dosing with the drug (218 mmol h/L) compared with placebo (883 mmol h/L; P = 0.003). The singl...

journal_title：Alimentary pharmacology & therapeutics

authors： Gavey CJ,Smith JT,Nwokolo CU,Pounder RE

更新日期：1989-12-01 00:00:00

abstract：AIM:To study the effect of prokinetic treatment with cisapride in patients with constipation-predominant irritable bowel syndrome. PATIENTS AND METHODS:Ninety-six patients were randomly assigned to treatment with either cisapride 5 mg three times daily or placebo three times daily for a period of 12 weeks. The dosage ...

journal_title：Alimentary pharmacology & therapeutics

authors： Schütze K,Brandstätter G,Dragosics B,Judmaier G,Hentschel E

更新日期：1997-04-01 00:00:00

abstract：BACKGROUND:Tegaserod, a 5-hydroxytryptamine-4 receptor agonist, enhances gastric emptying, but its effects on proximal stomach function have not been studied. AIM:To study the effect of tegaserod on gastric compliance, accommodation and perception of distension in humans. METHODS:Nineteen healthy volunteers (10 femal...

journal_title：Alimentary pharmacology & therapeutics

authors： Tack J,Vos R,Janssens J,Salter J,Jauffret S,Vandeplassche G

更新日期：2003-11-15 00:00:00

abstract：BACKGROUND:Helicobacter-negative gastritis has been increasingly reported. Molecular techniques as the polymerase chain reaction (PCR) may detect bacterial DNA in histologically negative gastritis. AIM:To evaluate of Helicobacter PCR in gastric biopsies for the daily diagnostics of Helicobacter-negative gastritis. ME...

journal_title：Alimentary pharmacology & therapeutics

authors： Kiss S,Zsikla V,Frank A,Willi N,Cathomas G

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:In 1997-1998, 6127 asymptomatic children aged 2-4 years were screened for coeliac disease (CD) by anti-endomysium (EmA) testing in the Netherlands. After 6 (+/-2) months, biopsies were performed in 57 seropositive children; 31(54%) had villous atrophy, but 26 (46%), all HLA-DQ2/DQ8 positive, had normal histo...

journal_title：Alimentary pharmacology & therapeutics

authors： Hogen Esch CE,Csizmadia GD,van Hoogstraten IM,Schreurs MW,Mearin ML,von Blomberg BM

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND:Benzodiazepines are used as sedatives for some intestinal procedures and as hypnotics, and this is the reason for studying their effects on duodenojejunal motility. METHODS:Antroduodenojejunal manometry was performed in 13 healthy volunteers on two different occasions, when placebo or midazolam were given i...

journal_title：Alimentary pharmacology & therapeutics

authors： Castedal M,Björnsson E,Abrahamsson H

更新日期：2000-05-01 00:00:00

abstract：BACKGROUND:It is not clear whether the incidence or early mortality related to peptic ulcer perforation has changed. AIM:To evaluate the incidence and mortality related to peptic ulcer perforation while considering the intake of low-dose aspirin and nonsteroidal anti-inflammatory drugs (NSAIDs). METHODS:We recorded t...

journal_title：Alimentary pharmacology & therapeutics

authors： Taha AS,Angerson WJ,Prasad R,McCloskey C,Gilmour D,Morran CG

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND:Proton pump inhibitors may interfere with the accuracy of the (13)C-urea breath test, but little information is available on the effect of standard doses of various proton pump inhibitors on this test. AIM:To evaluate the effect of short-term standard doses of omeprazole, lansoprazole and pantoprazole on th...

journal_title：Alimentary pharmacology & therapeutics

authors： Parente F,Sainaghi M,Sangaletti O,Imbesi V,Maconi G,Anderloni A,Bianchi Porro G

更新日期：2002-03-01 00:00:00