当前位置： SCI文献检索 > ALIMENTARY PHARMACOLOGY & THERAPEUTICS期刊下所有文献 > Comparative study of characteristics and disease management between subjects with frequent and occasional gastro-oesophageal reflux symptoms.

Comparative study of characteristics and disease management between subjects with frequent and occasional gastro-oesophageal reflux symptoms.

Abstract：

BACKGROUND:Little is known about the distinctive characteristics of subjects with frequent (at least weekly) and occasional gastro-oesophageal reflux symptoms. AIM:To compare the characteristics and disease management of subjects complaining of at least weekly and less frequent gastro-oesophageal reflux symptoms. METHODS:Population-based postal survey carried out in France in 2003 among a representative sample of 8000 subjects. RESULTS:The prevalence of frequent and occasional gastro-oesophageal reflux symptoms was 7.8% and 23.4%, respectively. Compared to subjects with occasional gastro-oesophageal reflux symptoms, those with frequent symptoms were older, suffered from more severe symptoms and felt greater impact on daily living, despite a slightly shorter duration of symptoms. These subjects more often sought medical advice. Most of them had treated the last episode of symptoms primarily with a proton-pump inhibitor and less often with antacids/alginates. The degree of treatment satisfaction was lower in subjects with frequent gastro-oesophageal reflux symptoms, in relation to a more frequently observed persistence of symptoms irrespective of the medication used except for proton-pump inhibitors. CONCLUSIONS:This survey suggests that subjects complaining of frequent or occasional gastro-oesophageal reflux symptoms constitute two distinctive groups. Despite greater healthcare use, the former group shows a lower level of satisfaction with disease management. Nevertheless, a substantial subset of subjects with occasional symptoms also complained of impaired health-related quality of life and sought health care.

journal_name

Aliment Pharmacol Ther

journal_title

Alimentary pharmacology & therapeutics

authors

Bretagne JF,Honnorat C,Richard-Molard B,Caekaert A,Barthélemy P

doi

10.1111/j.1365-2036.2006.02811.x

subject

Has Abstract

pub_date

2006-03-01 00:00:00

pages

607-16

issue

5

eissn

0269-2813

issn

1365-2036

pii

APT2811

journal_volume

23

pub_type

杂志文章

相关文献

ALIMENTARY PHARMACOLOGY & THERAPEUTICS文献大全
  • Pilot study: Gelafundin (polygeline) 4% plus antibiotics in the treatment of high-risk cirrhotic patients with spontaneous bacterial peritonitis.

    abstract：BACKGROUND:Cirrhotic patients with spontaneous bacterial peritonitis (SBP) have elevated rates of renal impairment and mortality. It has been shown that cefotaxime plus albumin infusion decrease renal impairment compared with antibiotic treatment alone, in patients with serum bilirubin >4 mg/dL or creatinine >1 mg/dL. ...

    journal_title：Alimentary pharmacology & therapeutics

    pub_type： 杂志文章

    doi：10.1111/j.1365-2036.2010.04309.x

    authors： Cartier M,Terg R,Lucero R,Muñoz A,Romero G,Levi D,Miguez C,Abecasis R

    更新日期：2010-07-01 00:00:00

  • Risk of colorectal adenomas in patients with coeliac disease.

    abstract：BACKGROUND:Coeliac disease is associated with an increased risk of lymphoma and small bowel malignancy, but most studies have found no increased risk of colorectal cancer. AIM:To compare the prevalence of colorectal adenomas in coeliac disease patients with that in non-coeliac disease controls. METHODS:We identified ...

    journal_title：Alimentary pharmacology & therapeutics

    pub_type： 杂志文章

    doi：10.1111/j.1365-2036.2010.04440.x

    authors： Lebwohl B,Stavsky E,Neugut AI,Green PH

    更新日期：2010-10-01 00:00:00

  • Mycophenolate mofetil in refractory inflammatory bowel disease.

    abstract：BACKGROUND:Mycophenolate mofetil has been claimed to be effective and well tolerated in refractory inflammatory bowel disease although there is little information regarding its use in clinical practice. AIM:To review our experience in achieving and maintaining remission in refractory inflammatory bowel disease and to ...

    journal_title：Alimentary pharmacology & therapeutics

    pub_type： 杂志文章

    doi：10.1046/j.1365-2036.2003.01581.x

    authors： Ford AC,Towler RJ,Moayyedi P,Chalmers DM,Axon AT

    更新日期：2003-06-01 00:00:00

  • Clinical trial: oral zinc in hepatic encephalopathy.

    abstract：BACKGROUND:Hepatic encephalopathy has a negative effect on patient health-related quality of life (HRQOL). Zinc supplementation has been effective with regard to altered nitrogen metabolism. AIM:To investigate the effectiveness of oral zinc supplementation on hepatic encephalopathy and HRQOL. METHODS:Seventy-nine cir...

    journal_title：Alimentary pharmacology & therapeutics

    pub_type： 杂志文章,随机对照试验

    doi：10.1111/j.1365-2036.2010.04448.x

    authors： Takuma Y,Nouso K,Makino Y,Hayashi M,Takahashi H

    更新日期：2010-11-01 00:00:00

  • Meta-analysis: insulin sensitizers for the treatment of non-alcoholic steatohepatitis.

    abstract：BACKGROUND:Non-alcoholic fatty liver disease generally has a benign course; however, patients with non-alcoholic steatohepatitis (NASH) may progress to cirrhosis and hepatocellular carcinoma. Currently, there is a lack of consensus about optimal NASH treatment. AIM:To assess the efficacy of insulin-sensitizing agents ...

    journal_title：Alimentary pharmacology & therapeutics

    pub_type： 杂志文章,meta分析

    doi：10.1111/j.1365-2036.2010.04467.x

    authors： Rakoski MO,Singal AG,Rogers MA,Conjeevaram H

    更新日期：2010-11-01 00:00:00

  • Review article: can post-operative recurrence in Crohn's disease be prevented?

    abstract：:The decision regarding prophylactic treatment after surgery in Crohn's disease (CD) requires a good estimation of the risk of recurrence. It is also important to consider the consequences of recurrence for the patient, and the risks and benefits of treatment, bearing in mind that it will be given over a long period. S...

    journal_title：Alimentary pharmacology & therapeutics

    pub_type： 杂志文章,评审

    doi：10.1111/j.1365-2036.2006.03055.x

    authors： Lémann M

    更新日期：2006-10-01 00:00:00

  • Review article: intra-oesophageal impedance monitoring for the assessment of bolus transit and gastro-oesophageal reflux.

    abstract：BACKGROUND:Intra-oesophageal impedance monitoring can be used to assess the clearance of a swallowed bolus (oesophageal transit) and to detect gastro-oesophageal reflux independent of its acidity. AIM:To discuss the clinical application of the impedance technique for the assessment of bolus transit and gastro-oesophag...

    journal_title：Alimentary pharmacology & therapeutics

    pub_type： 杂志文章,评审

    doi：10.1111/j.1365-2036.2008.03863.x

    authors： Conchillo JM,Smout AJ

    更新日期：2009-01-01 00:00:00

  • Relationship between the Fibrotest and portal hypertension in patients with liver disease.

    abstract：BACKGROUND:The best technique to estimate portal hypertension (PHT) is to measure the hepatic venous pressure gradient (HVPG), which is an invasive method. AIM:To assess the relationship between the Fibrotest (Biopredictive, Paris, France) and the presence and degree of PHT in patients with liver disease, and to deter...

    journal_title：Alimentary pharmacology & therapeutics

    pub_type： 杂志文章

    doi：10.1111/j.1365-2036.2007.03378.x

    authors： Thabut D,Imbert-Bismut F,Cazals-Hatem D,Messous D,Muntenau M,Valla DC,Moreau R,Poynard T,Lebrec D

    更新日期：2007-08-01 00:00:00

  • Systematic review: worldwide variation in the frequency of coeliac disease and changes over time.

    abstract：BACKGROUND:Coeliac disease (CD), originally thought to be largely confined to Northern Europe and Australasia and uncommon in North America and the Middle East, is now recognised to be equally common in all these countries. It is still thought to be rare in the Orient and Sub-Saharan Africa. AIM:To assess geographical...

    journal_title：Alimentary pharmacology & therapeutics

    pub_type： 杂志文章,评审

    doi：10.1111/apt.12373

    authors： Kang JY,Kang AH,Green A,Gwee KA,Ho KY

    更新日期：2013-08-01 00:00:00

  • Age-dependent eradication of Helicobacter pylori with dual therapy.

    abstract：BACKGROUND:Combined treatment using an acid-inhibiting drug with antibiotics can cure Helicobacter pylori infection. However, eradication rates are highly variable, especially if a proton pump inhibitor is used with amoxycillin. Therefore it is important to define factors/predictors of the clinical outcome. METHODS:In...

    journal_title：Alimentary pharmacology & therapeutics

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1046/j.1365-2036.1997.00210.x

    authors： Treiber G,Ammon S,Klotz U

    更新日期：1997-08-01 00:00:00

  • Clarithromycin-amoxycillin therapy for Helicobacter pylori infection.

    abstract：BACKGROUND:More convenient therapies are needed to treat Helicobacter pylori infection successfully. Clarithromycin and amoxycillin are effective against H. pylori both in vivo and in vitro. Recent success with a high dose amoxycillin-metronidazole combination therapy led us to evaluate clarithromycin-amoxycillin dual ...

    journal_title：Alimentary pharmacology & therapeutics

    pub_type： 临床试验,杂志文章

    doi：10.1111/j.1365-2036.1994.tb00313.x

    authors： al-Assi MT,Genta RM,Karttunen TJ,Graham DY

    更新日期：1994-08-01 00:00:00

  • Effect of mefenamic acid on bowel transit time in healthy adult volunteers.

    abstract：:The effect of mefenamic acid on bowel transit time was investigated. Seven healthy adult male subjects of age 39 +/- 2.4 years (mean +/- S.E.M.) received placebo or mefenamic acid (500 mg t.d.s) orally in randomized order for five days, with a 7-day washout between studies. On the third morning after starting the drug...

    journal_title：Alimentary pharmacology & therapeutics

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1111/j.1365-2036.1990.tb00488.x

    authors： Rashid MU,Bateman DN

    更新日期：1990-08-01 00:00:00

  • Efficacy of esomeprazole for resolution of symptoms of heartburn and acid regurgitation in continuous users of non-steroidal anti-inflammatory drugs.

    abstract：BACKGROUND:The use of non-steroidal anti-inflammatory drugs (NSAIDs) is often associated with upper gastrointestinal symptoms such as heartburn and acid regurgitation. AIM:To assess the efficacy of esomeprazole 20 and 40 mg for resolution of heartburn and acid regurgitation in continuous NSAIDs. METHODS:A post hoc an...

    journal_title：Alimentary pharmacology & therapeutics

    pub_type： 杂志文章,meta分析

    doi：10.1111/j.1365-2036.2006.03210.x

    authors： Hawkey CJ,Jones RH,Yeomans ND,Scheiman JM,Talley NJ,Goldstein JL,Ahlbom H,Naesdal J

    更新日期：2007-04-01 00:00:00

  • Depression is associated with non-alcoholic fatty liver disease among adults in the United States.

    abstract：BACKGROUND:Currently, the relationship between depression and non-alcoholic fatty liver disease (NAFLD) is not clearly defined. AIM:To determine whether depression is associated with NAFLD and NAFLD-related advanced fibrosis in a large population sample. METHODS:We performed a cross-sectional analysis using the 2007-...

    journal_title：Alimentary pharmacology & therapeutics

    pub_type： 杂志文章

    doi：10.1111/apt.15395

    authors： Kim D,Yoo ER,Li AA,Tighe SP,Cholankeril G,Harrison SA,Ahmed A

    更新日期：2019-09-01 00:00:00

  • Predictors of severe outcomes associated with Clostridium difficile infection in patients with inflammatory bowel disease.

    abstract：BACKGROUND:The increasing incidence of Clostridium difficile (C. difficile) infection (CDI) among patients with inflammatory bowel disease is well recognised. However, most studies have focused on demonstrating that CDI is associated with adverse outcomes in IBD patients. Few have attempted to identify predictors of se...

    journal_title：Alimentary pharmacology & therapeutics

    pub_type： 杂志文章,多中心研究

    doi：10.1111/j.1365-2036.2012.05022.x

    authors： Ananthakrishnan AN,Guzman-Perez R,Gainer V,Cai T,Churchill S,Kohane I,Plenge RM,Murphy S

    更新日期：2012-04-01 00:00:00

  • Effect of Helicobacter pylori eradication on duodenal ulcer scar in patients with no clinical history of duodenal ulcer.

    abstract：BACKGROUND:Helicobacter pylori eradication has become the standard treatment for duodenal ulcer. However, there is no relevant evidence for antibacterial treatment of the white scar stage of duodenal ulcer (duodenal ulcer scar) in patients with no past history of duodenal ulcer. AIM:To investigate whether H. pylori er...

    journal_title：Alimentary pharmacology & therapeutics

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1046/j.1365-2036.2002.01174.x

    authors： Kim JS,Kim SG,Choi IJ,Park MJ,Kim BG,Jung HC,Song IS

    更新日期：2002-02-01 00:00:00

  • Clinical, endoscopic and radiographic outcomes with ustekinumab in medically-refractory Crohn's disease: real world experience from a multicentre cohort.

    abstract：BACKGROUND:Ustekinumab is a monoclonal antibody targeting interleukins-12 and -23, with efficacy in Crohn's disease (CD) demonstrated in clinical trials. AIM:To assess the real-world clinical, endoscopic and radiographic response and remission outcomes achieved with ustekinumab in medically-refractory CD. METHODS:A r...

    journal_title：Alimentary pharmacology & therapeutics

    pub_type： 杂志文章,多中心研究

    doi：10.1111/apt.14016

    authors： Ma C,Fedorak RN,Kaplan GG,Dieleman LA,Devlin SM,Stern N,Kroeker KI,Seow CH,Leung Y,Novak KL,Halloran BP,Huang VW,Wong K,Blustein PK,Ghosh S,Panaccione R

    更新日期：2017-05-01 00:00:00

  • Systematic review: has disease outcome in Crohn's disease changed during the last four decades?

    abstract：BACKGROUND:Disease outcome in Crohn's disease might have changed during the last four decades. Disease outcome measurement in Crohn's disease has methodological difficulties because of patient selection and lack of proper definition of diagnostic and outcome measurement criteria. AIM:To assess possible changes in dise...

    journal_title：Alimentary pharmacology & therapeutics

    pub_type： 杂志文章,评审

    doi：10.1111/j.1365-2036.2004.02123.x

    authors： Wolters FL,Russel MG,Stockbrügger RW

    更新日期：2004-09-01 00:00:00

  • A regional audit of iatrogenic perforation of tumours of the oesophagus and cardia.

    abstract：INTRODUCTION:With the rising incidence of oesophageal cancer, palliative treatment has an increasingly important role. With median survival unlikely to exceed 6 months, in advanced disease the palliative therapy chosen must not hasten patient's demise. AIM:To establish the outcome of both modern and historical palliat...

    journal_title：Alimentary pharmacology & therapeutics

    pub_type： 杂志文章,多中心研究

    doi：10.1111/j.1365-2036.2005.02324.x

    authors： Jethwa P,Lala A,Powell J,McConkey CC,Gillison EW,Spychal RT

    更新日期：2005-02-15 00:00:00

  • Fatty liver indices in the multiethnic United States National Health and Nutrition Examination Survey.

    abstract：BACKGROUND:Validated non-invasive measures of fatty liver are needed that can be applied across populations and over time. A fatty liver index (FLI) including body mass index, waist circumference, triglycerides and gamma glutamyltransferase (GGT) activity was developed in an Italian municipality, but has not been valid...

    journal_title：Alimentary pharmacology & therapeutics

    pub_type： 杂志文章

    doi：10.1111/apt.13012

    authors： Ruhl CE,Everhart JE

    更新日期：2015-01-01 00:00:00

  • Circulating microRNA146b-5p is superior to C-reactive protein as a novel biomarker for monitoring inflammatory bowel disease.

    abstract：BACKGROUND:Owing to the importance of early treatment, simple and reliable methods for monitoring inflammatory bowel disease (IBD) are needed. AIMS:To determine whether circulating microRNAs are reliable biomarkers for IBD monitoring. METHODS:Serum levels of 17 candidate microRNAs were measured by quantitative real-t...

    journal_title：Alimentary pharmacology & therapeutics

    pub_type： 杂志文章

    doi：10.1111/apt.15159

    authors： Chen P,Li Y,Li L,Yu Q,Chao K,Zhou G,Qiu Y,Feng R,Huang S,He Y,Chen B,Chen M,Zeng Z,Zhang S

    更新日期：2019-03-01 00:00:00

  • Clinical predictors of fibrosis in patients with chronic liver disease.

    abstract：BACKGROUND:Patients with chronic liver disease and components of metabolic syndrome may be at higher risk for fibrosis. AIM:To assess the impact of clinicodemographic factors on hepatic fibrosis in CLD. METHODS:Of 1028 chronic liver disease patients, 964 were included in the analysis. Extensive clinico-demographic an...

    journal_title：Alimentary pharmacology & therapeutics

    pub_type： 杂志文章

    doi：10.1111/j.1365-2036.2010.04266.x

    authors： Stepanova M,Aquino R,Alsheddi A,Gupta R,Fang Y,Younossi Z

    更新日期：2010-05-01 00:00:00

  • Predictors of relapse following infliximab de-escalation in patients with inflammatory bowel disease: the value of a strategy based on therapeutic drug monitoring.

    abstract：BACKGROUND:There are limited data concerning infliximab drug monitoring during de-escalation of the treatment of inflammatory bowel disease (IBD). AIM:To define the rate and the predictors of relapse following infliximab de-escalation in IBD patients in remission. METHODS:All IBD patients at a single referral centre ...

    journal_title：Alimentary pharmacology & therapeutics

    pub_type： 杂志文章

    doi：10.1111/apt.15046

    authors： Lucidarme C,Petitcollin A,Brochard C,Siproudhis L,Dewitte M,Landemaine A,Bellissant E,Bouguen G

    更新日期：2019-01-01 00:00:00

  • Review article: the medical management of Crohn's disease.

    abstract：:The choice of medical therapies for Crohn's disease continues to grow. Although our understanding of the mechanisms of the disease is incomplete, increasing knowledge of the pathogenesis of inflammation in general and Crohn's disease in particular allows targeting of therapies at various points in the immunoinflammato...

    journal_title：Alimentary pharmacology & therapeutics

    pub_type： 杂志文章,评审

    doi：10.1111/j.1365-2036.1996.tb00173.x

    authors： Elton E,Hanauer SB

    更新日期：1996-02-01 00:00:00

  • A population-based study of coeliac disease, neurodegenerative and neuroinflammatory diseases.

    abstract：BACKGROUND:It has been suggested that coeliac disease (CD) is associated with several neurological diseases. However, the evidence of such an association is inconclusive as earlier research has often been based on small numbers with retrospective data collection. AIM:To use Cox regression to examine the risk of neurol...

    journal_title：Alimentary pharmacology & therapeutics

    pub_type： 杂志文章

    doi：10.1111/j.1365-2036.2007.03329.x

    authors： Ludvigsson JF,Olsson T,Ekbom A,Montgomery SM

    更新日期：2007-06-01 00:00:00

  • Accuracy of the stool antigen test in the diagnosis of Helicobacter pylori infection before treatment and in patients on omeprazole therapy.

    abstract：AIM:To evaluate the Helicobacter pylori stool antigen (HpSA) test in the assessment of H. pylori infection and the effect of omeprazole treatment on its accuracy. METHODS:Study 1: 140 dyspeptic patients were enrolled in the study and defined as H. pylori positive if histology and rapid urease test, or culture alone we...

    journal_title：Alimentary pharmacology & therapeutics

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1046/j.1365-2036.2001.00907.x

    authors： Manes G,Balzano A,Iaquinto G,Ricci C,Piccirillo MM,Giardullo N,Todisco A,Lioniello M,Vaira D

    更新日期：2001-01-01 00:00:00

  • The organ extraction and splanchnic haemodynamic effects of octreotide in cirrhotic patients.

    abstract：BACKGROUND:Intravenous octreotide is an established treatment of oesophageal variceal haemorrhage in the cirrhotic patient. AIM:To examine the organ extraction and splanchnic haemodynamic effects of octreotide in cirrhotic patients with portal hypertension. METHODS:Thirteen patients with cirrhosis had hepatic venous ...

    journal_title：Alimentary pharmacology & therapeutics

    pub_type： 临床试验,杂志文章

    doi：10.1046/j.1365-2036.1998.00353.x

    authors： Ottesen LH,Flyvbjerg A,Møller S,Bendtsen F

    更新日期：1998-07-01 00:00:00

  • Only four days of quadruple therapy can effectively cure Helicobacter pylori infection.

    abstract：AIM:To determine whether 4 days of quadruple therapy using bismuth, tetracycline and metronidazole combined with omeprazole is effective treatment for Helicobacter pylori infection. METHODS:Non-ulcer dyspepsia, as well as chronic peptic ulcer patients with biopsy-proven H. pylori infection received 4 days of quadruple...

    journal_title：Alimentary pharmacology & therapeutics

    pub_type： 临床试验,杂志文章

    doi：10.1111/j.1365-2036.1995.tb00432.x

    authors： De Boer WA,Driessen WM,Tytgat GN

    更新日期：1995-12-01 00:00:00

  • Review article: the incidence and risk factors for irritable bowel syndrome in population-based studies.

    abstract：BACKGROUND:In the absence of prior gastrointestinal infection, the risk factors for irritable bowel syndrome (IBS) are not well established. AIM:To identify the incidence and risk factors for IBS in general population samples METHODS: Narrative review of population-based studies. Electronic databases were searched usi...

    journal_title：Alimentary pharmacology & therapeutics

    pub_type： 杂志文章,评审

    doi：10.1111/apt.15396

    authors： Creed F

    更新日期：2019-09-01 00:00:00

  • Review article: the management of Crohn's disease and ulcerative colitis during pregnancy and lactation.

    abstract：BACKGROUND:Inflammatory bowel diseases (IBD) commonly affect young patients in the reproductive phase of their lives. The chronic and relapsing nature of IBD and the potential need for medical or surgical interventions raise concerns about family planning issues. AIM:To review the current knowledge on IBD management i...

    journal_title：Alimentary pharmacology & therapeutics

    pub_type： 杂志文章,评审

    doi：10.1111/apt.12949

    authors： Schulze H,Esters P,Dignass A

    更新日期：2014-11-01 00:00:00