Stomach cancer among New Mexico's American Indians, Hispanic whites, and non-Hispanic whites.

Abstract:

:Stomach cancer incidence rates vary by ethnic group in New Mexico, with American Indians and Hispanic Whites at higher risk than the state's non-Hispanic White population. To further characterize the descriptive epidemiology of this disease in New Mexico, we investigated temporal trends in stomach cancer mortality and incidence rates. Stomach cancer mortality rates declined over a 25-year period (1958-1982) among New Mexico's Hispanic and non-Hispanic Whites. Birth cohort analysis suggests that much of the decline was achieved prior to 1968. Stomach cancer mortality rates did not drop among American Indians during the same period. Stomach cancer incidence rates remained constant for Hispanic Whites, non-Hispanic Whites, and American Indian males over a 13-year period (1969-1982), but more than doubled among American Indian females. Although environmental factors have been implicated in the etiology of stomach cancer, little is currently known about the distribution of such risk factors among the ethnic groups described in this report. The environmental and biological correlates of sex, ethnicity, and socioeconomic status that determine stomach cancer risk merit further investigation in New Mexico.

journal_name

Cancer Res

journal_title

Cancer research

authors

Wiggins CL,Becker TM,Key CR,Samet JM

subject

Has Abstract

pub_date

1989-03-15 00:00:00

pages

1595-9

issue

6

eissn

0008-5472

issn

1538-7445

journal_volume

49

pub_type

杂志文章
  • Importance of epidermal growth factor in implantation and growth of mouse mammary tumor in female nude mice.

    abstract::In female nude mice, epidermal growth factor (EGF) was present at a mean concentration of 42.8 +/- 16.9 (SD) ng/mg wet tissue in the submandibular gland and 0.28 +/- 0.13 ng/ml in the plasma. Sialoadenectomy (removal of the submandibular glands) decreased circulating EGF to undetectable levels (less than 0.1 ng/ml). T...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:

    authors: Tsutsumi O,Tsutsumi A,Oka T

    更新日期:1987-09-01 00:00:00

  • Mesothelial cell transformation requires increased AP-1 binding activity and ERK-dependent Fra-1 expression.

    abstract::Mesothelioma is a unique and insidious tumor associated historically with occupational exposure to asbestos. The transcription factor, activator protein-1 (AP-1) is a major target of asbestos-induced signaling pathways. Here, we demonstrate that asbestos-induced mesothelial cell transformation is linked to increases i...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:

    authors: Ramos-Nino ME,Timblin CR,Mossman BT

    更新日期:2002-11-01 00:00:00

  • Therapeutic efficacy of long duration-low temperature whole body hyperthermia when combined with tumor necrosis factor and carboplatin in rats.

    abstract::This study examines the effects of a combined modality regimen of long duration-low temperature whole body hyperthermia (6 h at 40.0 degrees C; LL-WBH), recombinant human tumor necrosis factor-alpha (TNF) and carboplatin (CBDCA) on a transplantable fibrosarcoma as well as normal tissue. We compare LL-WBH with short du...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:

    authors: Sakaguchi Y,Makino M,Kaneko T,Stephens LC,Strebel FR,Danhauser LL,Jenkins GN,Bull JM

    更新日期:1994-04-15 00:00:00

  • Inhibition of hepatic phosphoenolpyruvate carboxykinase by avian reticuloendotheliosis viruses.

    abstract::Severe weight loss is associated with many malignant diseases of humans and animals. Avian reticuloendotheliosis viruses (RE viruses) induce runting in experimentally infected chickens. Chickens infected with a replication-competent RE virus, reticuloendotheliosis-associated virus, weighed 30-50% less than control bir...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:

    authors: Garry RF,Shackleford GM,Berry LJ,Bose HR Jr

    更新日期:1985-10-01 00:00:00

  • Expression pattern of chemokine receptor 6 (CCR6) and CCR7 in squamous cell carcinoma of the head and neck identifies a novel metastatic phenotype.

    abstract::Squamous cell carcinoma of the head and neck (SCCHN) metastasizes predictably to cervical lymph nodes, with low rates of distant metastases. Tumor cells can express various receptors that facilitate such metastatic spread to lymph nodes and other nonlymphoid organs. Chemokine receptors (CCR), normally expressed on lym...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:10.1158/0008-5472.can-03-2968

    authors: Wang J,Xi L,Hunt JL,Gooding W,Whiteside TL,Chen Z,Godfrey TE,Ferris RL

    更新日期:2004-03-01 00:00:00

  • Prognostically important chromosomal aberrations in soft tissue sarcomas: a report of the Chromosomes and Morphology (CHAMP) Study Group.

    abstract::Cytogenetic analysis has not only provided important information on the pathogenesis of soft tissue tumors but, by disclosing distinct chromosomal rearrangements in different histopathological entities, has also come to serve as a valuable diagnostic tool. Little is known as yet about the potential prognostic impact o...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:

    authors: Mertens F,Strömberg U,Mandahl N,Dal Cin P,De Wever I,Fletcher CD,Mitelman F,Rosai J,Rydholm A,Sciot R,Tallini G,Van Den Berghe H,Vanni R,Willén H

    更新日期:2002-07-15 00:00:00

  • Evidence of cumulative gene losses with progression of premalignant epithelial lesions to carcinoma of the bronchus.

    abstract::Human bronchial carcinoma is thought to develop through progressive stages from basal cell hyperplasia to squamous metaplasia, dysplasia, carcinoma in situ, and finally invasive cancer. In this study, we used tissue microdissection to examine loss of heterozygosity of chromosomes 3p21, 5q21, and 9p21 at each stage of ...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:

    authors: Thiberville L,Payne P,Vielkinds J,LeRiche J,Horsman D,Nouvet G,Palcic B,Lam S

    更新日期:1995-11-15 00:00:00

  • Suppression of the negative regulator LRIG1 contributes to ErbB2 overexpression in breast cancer.

    abstract::The ErbB2 receptor tyrosine kinase is overexpressed in approximately 25% of breast tumors and contributes to poor patient prognosis and therapeutic resistance. Here, we examine the role of the recently discovered ErbB negative regulator LRIG1 in ErbB2(+) breast cancer. We observe that LRIG1 protein levels are signific...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:10.1158/0008-5472.CAN-07-6316

    authors: Miller JK,Shattuck DL,Ingalla EQ,Yen L,Borowsky AD,Young LJ,Cardiff RD,Carraway KL 3rd,Sweeney C

    更新日期:2008-10-15 00:00:00

  • Mapping of ER gene CpG island methylation-specific polymerase chain reaction.

    abstract::Southern analysis has shown that DNA from 25% of primary estrogen receptor (ER) alpha-negative breast tumors displays aberrant methylation at one site within the ER gene CpG island. To examine more sites and increase sensitivity, we developed a methylation-specific PCR assay to map methylation of the entire ER CpG isl...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:

    authors: Lapidus RG,Nass SJ,Butash KA,Parl FF,Weitzman SA,Graff JG,Herman JG,Davidson NE

    更新日期:1998-06-15 00:00:00

  • Complete regression of mouse hepatoma transplanted after partial hepatectomy and the immunological mechanism of such regression.

    abstract::We have investigated the effect of partial hepatectomy (HEP) on tumor growth. MH-134 hepatoma cells, which were inoculated in syngeneic C3H/He mice from 3 to 10 days after HEP, grew with a linear increase in size until 7 days, began to regress, and disappeared 14 days after the inoculation. The survival rate was 100%,...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:

    authors: Ono M,Tanaka N,Orita K

    更新日期:1986-10-01 00:00:00

  • Frequent loss of heterozygosity on chromosomes 1q, 5q, and 17p in human gastric carcinomas.

    abstract::Recently, loss or inactivation of genes at specific chromosomal loci has been considered to be one of the important mechanisms during the development of human tumors. In order to identify tumor suppressor genes for gastric carcinoma, we performed restriction fragment length polymorphism analysis on 48 human gastric ca...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:

    authors: Sano T,Tsujino T,Yoshida K,Nakayama H,Haruma K,Ito H,Nakamura Y,Kajiyama G,Tahara E

    更新日期:1991-06-01 00:00:00

  • Intrathecal gene therapy for malignant leptomeningeal neoplasia.

    abstract::In meningeal carcinomatosis, retroviral vector-producer cells can be introduced into the thecal sac and circulate in the cerebrospinal fluid to reach malignant tumor cells in the leptomeninges, release vector particles, and selectively infect and transfer a gene of interest to these cells. Gene transfer experiments wi...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:

    authors: Ram Z,Walbridge S,Oshiro EM,Viola JJ,Chiang Y,Mueller SN,Blaese RM,Oldfield EH

    更新日期:1994-04-15 00:00:00

  • p14ARF silencing by promoter hypermethylation mediates abnormal intracellular localization of MDM2.

    abstract::The INK4a/ARF locus encodes two distinct tumor suppressors, p16INK4a and p14ARF. Although the contribution of p16INK4a to human tumorigenesis through point mutation, deletion, and hypermethylation has been widely documented, little is known about specific p14ARF lesions and their consequences. Recent data indicate tha...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:

    authors: Esteller M,Cordon-Cardo C,Corn PG,Meltzer SJ,Pohar KS,Watkins DN,Capella G,Peinado MA,Matias-Guiu X,Prat J,Baylin SB,Herman JG

    更新日期:2001-04-01 00:00:00

  • Selective antitumor effect of novel protease-mediated photodynamic agent.

    abstract::A new approach to selective photodynamic therapy (PDT) was developed by designing chlorin e6 (Ce6)-containing macromolecules, which are sensitive to tumor-associated proteases. The agents are nontoxic in their native state but become fluorescent and produce singlet oxygen on protease conversion. Coupled with optimized...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:10.1158/0008-5472.CAN-06-0448

    authors: Choi Y,Weissleder R,Tung CH

    更新日期:2006-07-15 00:00:00

  • Targeting the Chromosomal Passenger Complex Subunit INCENP Induces Polyploidization, Apoptosis, and Senescence in Neuroblastoma.

    abstract::Chromosomal passenger complex (CPC) has been demonstrated to be a potential target of cancer therapy by inhibiting Aurora B or survivin in different types of cancer including neuroblastoma. However, chemical inhibition of either Aurora B or survivin does not target CPC specifically due to off-target effects or CPC-ind...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:10.1158/0008-5472.CAN-19-0695

    authors: Sun M,Veschi V,Bagchi S,Xu M,Mendoza A,Liu Z,Thiele CJ

    更新日期:2019-10-01 00:00:00

  • Semaphorin 7A Promotes Macrophage-Mediated Lymphatic Remodeling during Postpartum Mammary Gland Involution and in Breast Cancer.

    abstract::Postpartum mammary gland involution is a tissue remodeling event that occurs in all mammals in the absence of nursing or after weaning to return the gland to the pre-pregnant state. The tissue microenvironment created by involution has proven to be tumor promotional. Here we report that the GPI-linked protein semaphor...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:10.1158/0008-5472.CAN-18-1642

    authors: Elder AM,Tamburini BAJ,Crump LS,Black SA,Wessells VM,Schedin PJ,Borges VF,Lyons TR

    更新日期:2018-11-15 00:00:00

  • Microsatellite instability of germ cell tumors is associated with resistance to systemic treatment.

    abstract::Systemic cisplatin-based chemotherapy cures > or =90% of patients with metastatic germ cell tumors (GCTs). The biological basis of this exquisite chemo-sensitivity and the resistant phenotype encountered in 10-15% of patients with GCT is yet unclear. A defective mismatch repair pathway leading to microsatellite instab...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:

    authors: Mayer F,Gillis AJ,Dinjens W,Oosterhuis JW,Bokemeyer C,Looijenga LH

    更新日期:2002-05-15 00:00:00

  • Amplification of cyclin genes in colorectal carcinomas.

    abstract::The genetic status of cyclin genes was examined in a panel of 47 colorectal carcinoma cell lines. Cyclin D2 was found to be amplified in one tumor and cyclin E in another. In each of the two cases, the amplified cyclin gene was overexpressed at the protein or mRNA level. Cyclin D1, previously shown to be amplified in ...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:

    authors: Leach FS,Elledge SJ,Sherr CJ,Willson JK,Markowitz S,Kinzler KW,Vogelstein B

    更新日期:1993-05-01 00:00:00

  • Sulindac sulfide-induced apoptosis involves death receptor 5 and the caspase 8-dependent pathway in human colon and prostate cancer cells.

    abstract::Sulindac is the most extensively investigated clinically relevant chemopreventive nonsteroidal anti-inflammatory drug. Sulindac sulfide is one of the major metabolites of sulindac that is believed to mediate its antitumorigenic effects by inducing apoptosis. Recent evidence suggests that sulindac sulfide engages the m...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:

    authors: Huang Y,He Q,Hillman MJ,Rong R,Sheikh MS

    更新日期:2001-09-15 00:00:00

  • An expression signature classifies chemotherapy-resistant pediatric osteosarcoma.

    abstract::Osteosarcoma is the most common malignant bone tumor in children. Osteosarcoma patients who respond poorly to chemotherapy are at a higher risk of relapse and adverse outcome. Therefore, it was the aim of this study to identify prognostic factors at the time of diagnosis to characterize the genes predictive of poor su...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:10.1158/0008-5472.CAN-04-2463

    authors: Mintz MB,Sowers R,Brown KM,Hilmer SC,Mazza B,Huvos AG,Meyers PA,Lafleur B,McDonough WS,Henry MM,Ramsey KE,Antonescu CR,Chen W,Healey JH,Daluski A,Berens ME,Macdonald TJ,Gorlick R,Stephan DA

    更新日期:2005-03-01 00:00:00

  • Overexpression of a rabbit liver carboxylesterase sensitizes human tumor cells to CPT-11.

    abstract::CPT-11 [7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecin ] is a prodrug that is converted to the active metabolite SN-38 by carboxylesterases. In its active form, the drug inhibits topoisomerase I, causes DNA damage, and induces apoptosis. Data in this study show metabolism of CPT-11 to SN-38 (7-ethyl...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:

    authors: Danks MK,Morton CL,Pawlik CA,Potter PM

    更新日期:1998-01-01 00:00:00

  • Mass Spectrometry Imaging Enables Discrimination of Renal Oncocytoma from Renal Cell Cancer Subtypes and Normal Kidney Tissues.

    abstract::Precise diagnosis and subtyping of kidney tumors are imperative to optimize and personalize treatment decision for patients. Patients with the most common benign renal tumor, renal oncocytomas, may be overtreated with surgical resection because of limited preoperative diagnostic methods that can accurately identify th...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:10.1158/0008-5472.CAN-19-2522

    authors: Zhang J,Li SQ,Lin JQ,Yu W,Eberlin LS

    更新日期:2020-02-15 00:00:00

  • Mutagenesis of Chinese hamster cells in vitro by combination treatments with methyl methanesulfonate and N-acetoxy-2-acetylaminofluorene.

    abstract::Mutational synergism was examined in Chinese hamster V79 cells exposed to methyl methanesulfonate followed by N-acetoxy-2-acetylaminofluorene (AcAAF) at different time intervals. Treatment with 500 micron methyl methanesulfonate resulted in 95% survival of cloning ability and induced approximately 4 azaguanine-resista...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:

    authors: Myhr BC,DiPaolo JA

    更新日期:1978-08-01 00:00:00

  • Chlorozotocin, 2-(3-(2-chloroethyl)-3-nitrosoureido)-D-glucopyranose, an antitumor agent with modified bone marrow toxicity.

    abstract::Chlorozotocin, 2-(3-(2-chloroethyl)-3-nitrosoureido)-D-glucopyranose, is a newly synthesized, water-soluble nitrosourea antitumor agent that is active against L1210 leukemia in mice. A 701% and a 401% increase in life-span were attained with a dose that was lethal to 10% of the animals (15 to 20 mg/kg, i.p.) in mice t...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:

    authors: Anderson T,McMenamin MG,Schein PS

    更新日期:1975-03-01 00:00:00

  • PDT: What's Past Is Prologue.

    abstract::Despite descriptions of light-mediated therapy in ancient texts and the discovery of photodynamic therapy (PDT) in the early 1900s, the landmark article in 1978 in Cancer Research by Dougherty and his colleagues at the Roswell Park Cancer Institute remains rightly viewed as the starting point for clinical PDT in moder...

    journal_title:Cancer research

    pub_type: 社论,历史文章

    doi:10.1158/0008-5472.CAN-16-0927

    authors: Cengel KA,Simone CB 2nd,Glatstein E

    更新日期:2016-05-01 00:00:00

  • eEF-2 kinase dictates cross-talk between autophagy and apoptosis induced by Akt Inhibition, thereby modulating cytotoxicity of novel Akt inhibitor MK-2206.

    abstract::Inhibition of the survival kinase Akt can trigger apoptosis, and also has been found to activate autophagy, which may confound tumor attack. In this study, we investigated regulatory mechanisms through which apoptosis and autophagy were modulated in tumor cells subjected to Akt inhibition by MK-2206, the first alloste...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:10.1158/0008-5472.CAN-10-2889

    authors: Cheng Y,Ren X,Zhang Y,Patel R,Sharma A,Wu H,Robertson GP,Yan L,Rubin E,Yang JM

    更新日期:2011-04-01 00:00:00

  • Hormonal treatment after cytotoxic therapy stimulates recovery of spermatogenesis.

    abstract::Previous studies have shown that treatment of rats with gonadotropin-releasing hormone (GnRH) analogues or steroids either before exposure to procarbazine or radiation or after irradiation enhances subsequent levels of spermatogenesis. We demonstrate here that giving a GnRH agonist after procarbazine injection also en...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:

    authors: Meistrich ML,Wilson G,Huhtaniemi I

    更新日期:1999-08-01 00:00:00

  • Normal human mesothelial cells and mesothelioma cell lines express insulin-like growth factor I and associated molecules.

    abstract::Insulin-like growth factor (IGF) I has important growth regulatory functions in normal growth and development. IGF-I is also a mitogen for a number of cancer cell lines; however, its autocrine effect has not been well established. In this study, the expression of IGF-I, its receptor, and its major serum-binding protei...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:

    authors: Lee TC,Zhang Y,Aston C,Hintz R,Jagirdar J,Perle MA,Burt M,Rom WN

    更新日期:1993-06-15 00:00:00

  • Genetic analysis of benign, low-grade, and high-grade ovarian tumors.

    abstract::Genetic abnormalities were assessed in 56 benign, low-, and high-grade ovarian tumors using comparative genomic hybridization (CGH) and analysis of loss of heterozygosity (LOH). In addition, 95 epithelial tumors were analyzed for microsatellite repeat instability. DNA sequence copy number abnormalities (CNAs) were not...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:

    authors: Iwabuchi H,Sakamoto M,Sakunaga H,Ma YY,Carcangiu ML,Pinkel D,Yang-Feng TL,Gray JW

    更新日期:1995-12-15 00:00:00

  • Acute changes of alpha-fetoprotein and human chorionic gonadotropin during induction chemotherapy of germ cell tumors.

    abstract::Thirty-seven consecutive patients with germ cell cancers (34 testicular, three extragonadal) and elevated serum levels of alpha-fetoprotein (AFP) and/or human chorionic gonadotropin (HCG) were treated with vinblastine, bleomycin, and cis-diamminedichloroplatinum induction chemotherapy. The AFP and/or HCG normalized in...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:

    authors: Vogelzang NJ,Lange PH,Goldman A,Vessela RH,Fraley EE,Kennedy BJ

    更新日期:1982-11-01 00:00:00