9. Cardiovascular Disease and Risk Management: Standards of Medical Care in Diabetes-2018.

abstract：OBJECTIVE:Serine-threonine kinase STK11 catalyzes the AMP-activated protein kinase complex. We tested the hypothesis that a gene variant in STK11 contributes to variation in insulin sensitivity and metformin efficacy. RESEARCH DESIGN AND METHODS:We studied the effects of a single nucleotide polymorphism (SNP) (rs81116...

journal_title：Diabetes care

authors： López-Bermejo A,Díaz M,Morán E,de Zegher F,Ibáñez L

更新日期：2010-07-01 00:00:00

abstract：OBJECTIVE:Exercise tolerance in patients with diabetes is frequently impaired due to noncardiac disease such as claudication and polyneuropathy. This study assesses the prognostic value of dobutamine stress myocardial perfusion imaging in patients with diabetes. RESEARCH DESIGN AND METHODS:A total of 207 consecutive d...

journal_title：Diabetes care

authors： Schinkel AF,Elhendy A,van Domburg RT,Bax JJ,Vourvouri EC,Sozzi FB,Valkema R,Roelandt JR,Poldermans D

更新日期：2002-09-01 00:00:00

abstract：OBJECTIVE:To assess the level of serum lipoprotein(a) [Lp(a)] in nonobese and obese NIDDM subjects with android body distribution. RESEARCH DESIGN AND METHODS:Serum Lp(a) levels were measured in 30 long-standing NIDDM patients (duration of diabetes 12.5 +/- 3 years, mean +/- SD), with 15 of the patients being obese of...

journal_title：Diabetes care

authors： Wassef N,Sidhom G,Zakareya el-K,Mohamed el-K

更新日期：1997-11-01 00:00:00

abstract：OBJECTIVE:Diabetes-related foot ulcers (DFUs) and their sequelae result in large patient and societal burdens. Long-term data determining the efficacy of individual glucose-lowering agents on DFUs are lacking. Using existing data from the Liraglutide Effect and Action in Diabetes: Evaluation of Cardiovascular Outcome R...

journal_title：Diabetes care

authors： Dhatariya K,Bain SC,Buse JB,Simpson R,Tarnow L,Kaltoft MS,Stellfeld M,Tornøe K,Pratley RE,LEADER Publication Committee on behalf of the LEADER Trial Investigators.

更新日期：2018-10-01 00:00:00

abstract：OBJECTIVE:We have previously suggested using the paired values of fasting plasma glucose (FPG) and HbA1c to identify potential diabetic subjects. In this article, we followed up on 208 nondiabetic subjects and examined their rates of progression to diabetes. We analyzed their likelihood of becoming diabetic according t...

journal_title：Diabetes care

authors： Ko GT,Chan JC,Tsang LW,Cockram CS

更新日期：2000-12-01 00:00:00

abstract：OBJECTIVE:Patients with diabetes due to hepatocyte nuclear factor (HNF)-1alpha mutations have beta-cell deficiency, insulin sensitivity, altered proinsulin levels, and a low renal threshold for glucose. It is uncertain how many of these features precede the development of diabetes. The aim of our study was to test for ...

journal_title：Diabetes care

authors： Stride A,Ellard S,Clark P,Shakespeare L,Salzmann M,Shepherd M,Hattersley AT

更新日期：2005-07-01 00:00:00

abstract：OBJECTIVE:We investigated the effect of glimepiride, a third-generation sulfonylurea hypoglycemic agent, on insulin resistance in elderly patients with type 2 diabetes, in connection with plasma adiponectin and 8-epi-prostagrandin F2alpha (8-epi-PGF2alpha), an oxidative stress marker. RESEARCH DESIGN AND METHODS:A tot...

journal_title：Diabetes care

authors： Tsunekawa T,Hayashi T,Suzuki Y,Matsui-Hirai H,Kano H,Fukatsu A,Nomura N,Miyazaki A,Iguchi A

更新日期：2003-02-01 00:00:00

abstract：OBJECTIVE:This epidemiological analysis of the pooled Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) cohort describes the equivalence of a 1-percentage point increase in HbA1c (such as from 7% to 8%) and years of additional age or duration of type 1 diabete...

journal_title：Diabetes care

authors： Bebu I,Braffett BH,Schade D,Sivitz W,Malone JI,Pop-Busui R,Lorenzi GM,Lee P,Trapani VR,Wallia A,Herman WH,Lachin JM,DCCT\/EDIC Research Group.

更新日期：2020-10-01 00:00:00

abstract：:Because the negative consequences of new-onset diabetes mellitus after transplantation (NODAT) diminish the significant gains of kidney transplantation, it is imperative to develop clinical interventions to reduce the incidence of NODAT. In this review, we discuss whether intensive lifestyle interventions that delay o...

journal_title：Diabetes care

authors： Chakkera HA,Weil EJ,Pham PT,Pomeroy J,Knowler WC

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVE:Diabetic retinopathy (DR) is a leading cause of vision loss worldwide. Screening for DR is recommended in children and adolescents, but adherence is poor. Recently, autonomous artificial intelligence (AI) systems have been developed for early detection of DR and have been included in the American Diabetes Ass...

journal_title：Diabetes care

authors： Wolf RM,Liu TYA,Thomas C,Prichett L,Zimmer Galler I,Smith K,Abramoff MD,Channa R

更新日期：2021-01-21 00:00:00

abstract：OBJECTIVE:To know the nutritional pattern of people with diabetes in Spain and that pattern's relationship with targets of metabolic control. RESEARCH DESIGN AND METHODS:The Diabetes Nutrition and Complications Trial (DNCT) is a prospective multicenter study designed to determine the nutritional behavior of diabetic p...

journal_title：Diabetes care

authors：

更新日期：1997-07-01 00:00:00

abstract：OBJECTIVE:In patients with clinical hemochromatosis, the frequency of diabetes ranges from 20 to 50%, and the heterozygosity for the C282Y mutation in the HFE gene might be associated with an increased risk for diabetes. There are also some reports that suggest that iron overload might cause diabetic nephropathy. RESE...

journal_title：Diabetes care

authors： Moczulski DK,Grzeszczak W,Gawlik B

更新日期：2001-07-01 00:00:00

abstract：OBJECTIVE:This national, population-based study reports diabetes incidence based on oral glucose tolerance tests (OGTTs) and identifies risk factors for diabetes in Australians. RESEARCH DESIGN AND METHODS:The Australian Diabetes, Obesity and Lifestyle Study followed-up 5,842 participants over 5 years. Normal glycemia...

journal_title：Diabetes care

authors： Magliano DJ,Barr EL,Zimmet PZ,Cameron AJ,Dunstan DW,Colagiuri S,Jolley D,Owen N,Phillips P,Tapp RJ,Welborn TA,Shaw JE

更新日期：2008-02-01 00:00:00

abstract：OBJECTIVE:Global usage of bariatric surgery has been dictated for the past quarter century by National Institutes of Health recommendations restricting these operations to individuals with a BMI ≥35 kg/m(2). Strong evidence now demonstrates that bariatric procedures markedly improve or cause remission of type 2 diabete...

journal_title：Diabetes care

authors： Cummings DE,Cohen RV

更新日期：2016-06-01 00:00:00

abstract：:In this study, 18 type I (insulin-dependent) diabetic subjects aged 22-35 yr (mean age 29.3) and within 10 yr of diagnosis (mean 7.7) performed a battery of cognitive and psychomotor tasks under conditions of hypoglycemia (50 mg/dl), normoglycemia (100 mg/dl), and hyperglycemia (300 mg/dl). Blood glucose levels during...

journal_title：Diabetes care

authors： Hoffman RG,Speelman DJ,Hinnen DA,Conley KL,Guthrie RA,Knapp RK

更新日期：1989-03-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to investigate whether genetic variants could influence the antidiabetic efficacy of gliclazide in type 2 diabetic patients. RESEARCH DESIGN AND METHODS:A total of 1,268 type 2 diabetic patients whose diabetes was diagnosed within the past 5 years and who had no recent hypoglyce...

journal_title：Diabetes care

authors： Feng Y,Mao G,Ren X,Xing H,Tang G,Li Q,Li X,Sun L,Yang J,Ma W,Wang X,Xu X

更新日期：2008-10-01 00:00:00

abstract：OBJECTIVE:The current study aimed to determine in the Diabetes Control and Complications Trial (DCCT)/Epidemiology of Diabetes Interventions and Complications cohort whether or not abnormal levels of markers of inflammation and endothelial dysfunction measured in samples collected at DCCT baseline were able to predict ...

journal_title：Diabetes care

authors： Lopes-Virella MF,Baker NL,Hunt KJ,Cleary PA,Klein R,Virella G,DCCT\/EDIC Research Group.

更新日期：2013-08-01 00:00:00

abstract：OBJECTIVE:Obesity is a well-known risk factor for vitamin D deficiency. We evaluated the interrelationship between vitamin D status, body size, and glucose homeostasis, measured by HbA1c (A1C). RESEARCH DESIGN AND METHODS:Data are from the survey of the 45-year-old 1958 British birth cohort (2002-2004). Information on...

journal_title：Diabetes care

authors： Hyppönen E,Power C

更新日期：2006-10-01 00:00:00

abstract：OBJECTIVE:We examined the associations of symptoms of sleep-disordered breathing (SDB), which was defined as loud snoring, stopping breathing for a while during sleep, and daytime sleepiness, and insomnia with glucose metabolism and incident type 2 diabetes in older adults. RESEARCH DESIGN AND METHODS:Between 1989 and...

journal_title：Diabetes care

authors： Strand LB,Carnethon M,Biggs ML,Djoussé L,Kaplan RC,Siscovick DS,Robbins JA,Redline S,Patel SR,Janszky I,Mukamal KJ

更新日期：2015-11-01 00:00:00

abstract：OBJECTIVE:To address whether hemodynamic responses in the cerebral arteries and OAs may be altered in patients with diabetic retinopathy. We used TCD to evaluate the effects of changes in BP, posture, and exercise on MCA and OA blood flow velocities. RESEARCH DESIGN AND METHODS:We evaluated 13 patients with BDR, 19 wi...

journal_title：Diabetes care

authors： Albert SG,Gomez CR,Russell S,Chaitman BR,Bernbaum M,Kong BA

更新日期：1993-02-01 00:00:00

abstract：OBJECTIVE:To investigate the possibility that leptin levels may be predictive of the risk of ischemic heart disease (IHD) through the relationship of leptin to body fat. RESEARCH DESIGN AND METHODS:The Quebec Cardiovascular Study cohort consisted of 2,103 French-Canadian men without IHD in 1985 who were followed until...

journal_title：Diabetes care

authors： Couillard C,Lamarche B,Mauriège P,Cantin B,Dagenais GR,Moorjani S,Lupien PJ,Després JP

更新日期：1998-05-01 00:00:00

abstract：:In past studies on the psychological aspects of diabetes mellitus, symptoms of depression have been identified as the most common manifestation among diabetic patients. Other psychological manifestations have been anxiety, hypochondriasis, increased dependence and passivity, and poor self-image. Ten insulin-dependent ...

journal_title：Diabetes care

authors： Dupuis A

更新日期：1980-01-01 00:00:00

abstract：OBJECTIVE:To estimate the long-run mortality effects of Hurricanes Katrina and Rita on seniors with diabetes. RESEARCH DESIGN AND METHODS:We performed a retrospective cohort analysis of Medicare enrollment and claims data covering four states and ∼10 years. Affected individuals were identified by whether they lived in...

journal_title：Diabetes care

authors： Quast T,Andel R,Sadhu AR

更新日期：2019-11-01 00:00:00

abstract：OBJECTIVE:Inflammatory processes have been implicated in the pathogenesis of painful neuropathy in rodents, but the relationship between inflammatory biomarkers and painful distal sensorimotor polyneuropathy (DSPN) has not been assessed in population-based studies. Therefore, we investigated whether circulating levels ...

journal_title：Diabetes care

authors： Herder C,Bongaerts BW,Rathmann W,Heier M,Kowall B,Koenig W,Thorand B,Roden M,Meisinger C,Ziegler D

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:Recipients of solid organ transplants have an increased risk of developing certain types of malignancies as compared with the general population. The majority of the literature has reported on neoplasms in kidney and heart transplant recipients. RESEARCH DESIGN AND METHODS:We describe 9 neoplasms occurring i...

journal_title：Diabetes care

authors： Martinenghi S,Dell'Antonio G,Secchi A,Di Carlo V,Pozza G

更新日期：1997-03-01 00:00:00

abstract：OBJECTIVE:Prior studies have supported that waist circumference correlates better with visceral adipose tissue and is a better predictor of cardiovascular disease than are BMI and waist-to-hip ratio. In this study, we reexamine the role of waist size on the risk of hypertension and type 2 diabetes in African-origin pop...

journal_title：Diabetes care

authors： Okosun IS,Cooper RS,Rotimi CN,Osotimehin B,Forrester T

更新日期：1998-11-01 00:00:00

abstract：OBJECTIVE:To study the metabolic effect and the variability of the effect elicited by inhalation of 87.2 U insulin powder combined with an absorption enhancer. The metabolic effect was compared with that of 10.2 U regular insulin injected subcutaneously and of 5.5 U regular insulin given intravenously RESEARCH DESIGN ...

journal_title：Diabetes care

authors： Heinemann L,Klappoth W,Rave K,Hompesch B,Linkeschowa R,Heise T

更新日期：2000-09-01 00:00:00

abstract：OBJECTIVE:Diabetes is a predictor of both coronary artery disease (CAD) and heart failure. It is unknown to what extent the association between diabetes and heart failure is influenced by other risk factors for heart failure. RESEARCH DESIGN AND METHODS:We evaluated the association of diabetes and A1C with incident he...

journal_title：Diabetes care

authors： van Melle JP,Bot M,de Jonge P,de Boer RA,van Veldhuisen DJ,Whooley MA

更新日期：2010-09-01 00:00:00

abstract：:Nine healthy volunteers with normal body weights were injected subcutaneously with 125I-labeled soluble human insulin (10 U) in one thigh and 133Xe in the contralateral thigh for the measurement of subcutaneous blood flow on 2 consecutive mornings. On one of the days, standardized massage of both injection sites was p...

journal_title：Diabetes care

authors： Linde B

更新日期：1986-11-01 00:00:00

abstract：OBJECTIVE:Recent studies show the importance of controlling blood glucose variability in relationship to both reducing hypoglycemia and attenuating the risk for cardiovascular and behavioral complications due to hyperglycemia. It is therefore important to design variability measures that are equally predictive of low a...

journal_title：Diabetes care

authors： Kovatchev BP,Otto E,Cox D,Gonder-Frederick L,Clarke W

更新日期：2006-11-01 00:00:00