Abstract:
BACKGROUND:Multiple comorbidities have been reported among rescue/recovery workers responding to the 9/11/2001 WTC disaster. In this study, we developed an index that quantifies the cumulative physiological burden of comorbidities and predicts life expectancy in this cohort. METHODS:A machine learning approach (gradient boosting) was used to model the relationship between mortality and several clinical parameters (laboratory test results, blood pressure, pulmonary function measures). This model was used to construct a risk index, which was validated by assessing its association with a number of health outcomes within the WTC general responder cohort. RESULTS:The risk index showed significant associations with mortality, self-assessed physical health, and onset of multiple chronic conditions, particularly COPD, hypertension, asthma, and sleep apnea. CONCLUSION:As an aggregate of several clinical parameters, this index serves as a cumulative measure of physiological dysregulation and could be utilized as a prognostic indicator of life expectancy and morbidity risk.
journal_name
Am J Ind Medjournal_title
American journal of industrial medicineauthors
Bello GA,Teitelbaum SL,Lucchini RG,Dasaro CR,Shapiro M,Kaplan JR,Crane MA,Harrison DJ,Luft BJ,Moline JM,Udasin IG,Todd ACdoi
10.1002/ajim.22786subject
Has Abstractpub_date
2018-01-01 00:00:00pages
63-76issue
1eissn
0271-3586issn
1097-0274journal_volume
61pub_type
杂志文章abstract:OBJECTIVE:To compare fatal and hospitalized nonfatal work-related traumatic injuries by occupation and cause. METHODS:Fatal and hospitalized nonfatal injuries occurring from 1991-1995 were identified from Washington State workers' compensation claims data. Nonfatal injuries were classified as severe if they had at lea...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/(sici)1097-0274(199908)36:2<317::aid-ajim1
更新日期:1999-08-01 00:00:00
abstract::Heat stress is a recognized occupational hazard in aluminum smelter pot rooms. This is the report of an unusual and complex case of heat-related illness in an aluminum smelter worker. The 34-year-old male US worker developed life-threatening heat-related illness in August 2018, on his first day back at work after a 7-...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.23061
更新日期:2019-12-01 00:00:00
abstract::Health care workers may be occupationally exposed to known and suspected teratogens including viruses, anesthetic gases, sterilants, mercury, and x-radiation. To assess the risk of congenital defects among offspring of health care workers, we analyzed parental occupational histories for 4,915 case babies with congenit...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700240103
更新日期:1993-07-01 00:00:00
abstract:BACKGROUND:Deaths due to occupational disease and injury place a heavy burden on society in terms of economic costs and human suffering. METHODS:We estimate the annual deaths due to selected diseases for which an occupational association is reasonably well established and quantifiable, by calculation of attributable f...
journal_title:American journal of industrial medicine
pub_type: 杂志文章,评审
doi:10.1002/ajim.10216
更新日期:2003-05-01 00:00:00
abstract:BACKGROUND:Metal fabrication workers experience high rates of traumatic occupational injuries. Machine operators in particular face high risks, often stemming from the absence or improper use of machine safeguarding or the failure to implement lockout procedures. METHODS:The National Machine Guarding Program (NMGP) wa...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22514
更新日期:2015-11-01 00:00:00
abstract:BACKGROUND:Work-related injuries in commercial fishing are of concern internationally. To better identify the causes of injury, this study coded occupational injuries by working processes in commercial fishing for fresh market fish. METHODS:A classification system of the work processes was developed by participation i...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20163
更新日期:2005-06-01 00:00:00
abstract::Blood histamine levels were measured by the bioassay of histamine (on an isolated strip of guinea pig ileum) in workers exposed to cotton dust in a textile mill in Ahmedabad. Byssinotic subjects showed very high levels of blood histamine as compared to nonbyssinotic and control subjects. The blood histamine levels wer...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700120409
更新日期:1987-01-01 00:00:00
abstract:BACKGROUND:No information exists on the differences between teenagers with work permits and teenagers without work permits in regards to workplace injury, near-miss incidents, and safety training. METHODS:In May 2003, an anonymous questionnaire was administered to 7,506 teens attending high school throughout the five ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20301
更新日期:2006-05-01 00:00:00
abstract:BACKGROUND:Mineral dusts that contain crystalline silica have been associated directly or indirectly with the development of pneumoconiosis or silicosis, non-malignant respiratory diseases, lung cancer, and other diseases. The health impacts on workers with silica mixed dust exposure in tin mines and dose-response rela...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20248
更新日期:2006-02-01 00:00:00
abstract:BACKGROUND:The Mine Safety and Health Administration (MSHA) proposes to issue citations for non-compliance with the exposure limit for respirable coal mine dust when measured exposure exceeds the exposure limit with a "high degree of confidence." This criterion threshold value (CTV) is derived from the sampling and ana...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20318
更新日期:2006-06-01 00:00:00
abstract::To study their socioeconomic and health status, 1,770 workers in the organized electronics industry in India were surveyed. Mean age of the workers employed in this industry was 32.5 +/- 6.01 years. The average per capita income/month was Rupees 333, indicating a higher socioeconomic status, compared with the status o...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700230209
更新日期:1993-02-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to examine the association between Dupuytren's contracture (DC), repetitive handwork (RHW), heavy handwork (HHW), and/or vibration exposure. METHODS:Frequency and intensity of the three types of handwork were collected and compared between DC patients and controls. Hours of wo...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22736
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND:Sensitivity to beryllium was investigated among workers at an aluminum smelter in Norway as a consequence of the findings in an occupational exposure survey. METHODS:Three hundred and sixty-two employees and 31 reference persons were tested for sensitization to beryllium with the beryllium lymphocyte prolif...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20816
更新日期:2010-07-01 00:00:00
abstract:BACKGROUND:Between 1987 and 1992, the Finnish Institute of Occupational Health (FIOH) initiated and implemented the Asbestos Program that aimed at reducing asbestos-related risks. It was a cooperative effort between government authorities, labor market organizations, and health care and labor protection personnel. MET...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20282
更新日期:2006-03-01 00:00:00
abstract::A five-year total community study of lung cancer incidence by occupation revealed that 1) virtually all the cases occurred in smokers; 2) all major histologic types of lung cancer were strongly associated with smoking behavior; 3) in most high-risk occupations the significant elevations of risk were limited to one or ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700030409
更新日期:1982-01-01 00:00:00
abstract:BACKGROUND:Use of worker's compensation (WC) as payer underestimates work-related (WR) injuries. We evaluated three methods to identify WR injuries: WC as payer, ICD-9-CM work-status codes E000.0/E000.1, and other ICD-9-CM external cause codes. METHODS:We identified injury-related emergency department visits from Nort...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22984
更新日期:2019-07-01 00:00:00
abstract:BACKGROUND:Studies comparing different forms of asbestos are rare, and limited by the failure to compare results with unexposed populations. We compare autoimmune responses among former workers and residents of the crocidolite mining and milling town of Wittenoom, Western Australia, with an unexposed population. METHO...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22863
更新日期:2018-07-01 00:00:00
abstract::The relationship between various occupational exposures and brain cancer was investigated in a case-control study using mortality data from 202 males who died in East Texas from gliomas in 1969-1978 and 238 male controls randomly selected from all deaths in East Texas in 1969-1978. Using the occupational classificatio...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700130603
更新日期:1988-01-01 00:00:00
abstract::Occupational health studies of agricultural workers have generally excluded migrant and seasonal farmworkers, and this population experiences a high degree of health risk from agricultural exposures. A survey of dermatologic disorders among migrant and seasonal farmworkers will be used to illustrate this point. Data f...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700180317
更新日期:1990-01-01 00:00:00
abstract:BACKGROUND:We compared performance of different exposure assessment approaches in a cohort study of cancer risk among European asphalt workers. METHODS:Three bitumen fume exposure indices (duration of exposure (years), average exposure (mg/m3) and cumulative exposure (mg/m3*years)) and two latency models (with and wit...
journal_title:American journal of industrial medicine
pub_type: 杂志文章,多中心研究
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更新日期:2003-01-01 00:00:00
abstract::To investigate the effects of styrene exposure on peripheral, central, and autonomic nervous system functions in man, we measured the distribution of nerve conduction velocities (DCV), short-latency somatosensory evoked potentials (SSEP), and variability in electrocardiographic R-R interval (CVRR) as well as conventio...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700200609
更新日期:1991-01-01 00:00:00
abstract:BACKGROUND:Hexavalent chromium is widely recognized to be a lung carcinogen. However, the U.S. Occupational Safety and Health Administration (OSHA) has failed to reduce the permissible exposure limit (PEL), despite having acknowledged in 1994 that the current limit is too high. In 1993, Public Citizen and the Paper, Al...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
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更新日期:2002-11-01 00:00:00
abstract:BACKGROUND:The extent that cigarette smoking may confound the relationship between diesel exhaust exposure and lung cancer was assessed in a retrospective cohort study of 55,395 U.S. railroad workers followed from 1959 to 1976. METHODS:The relative risk (RR) of lung cancer due to diesel exhaust was indirectly adjusted...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/1097-0274(200010)38:4<399::aid-ajim5>3.0.c
更新日期:2000-10-01 00:00:00
abstract::There is little known about the incidence of cancer among sewage workers. In this paper we examine findings from a retrospective cohort study of 487 white male sewer authority workers employed between January 1950 and October 1979. Vital status was ascertained for 93% of the cohort yielding a total of 6,886 person yea...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700190110
更新日期:1991-01-01 00:00:00
abstract::A study of 67 subjects in a small titanium oxide paint factory in Nigeria showed 50-54% frequency for airway symptoms, 20-40% for neurological symptoms, and 10-27% for other symptoms. The symptoms were well correlated with exposure (p less than .05) and pulmonary function tests (PFTs). The directly exposed subjects ha...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700120206
更新日期:1987-01-01 00:00:00
abstract::Standardized proportional mortality ratios and mortality odds ratios were calculated for 583 deaths between 1950 and 1986 among employees who had worked for at least 10 years at a facility manufacturing missile and aircraft guidance systems. There was a statistically significant excess of brain cancer proportional mor...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700170501
更新日期:1990-01-01 00:00:00
abstract::We evaluated the cost and yield of a general health surveillance program emphasizing the identification of occupationally related diseases among workers in a high-risk trade. Of approximately 4,000 eligible members of two local plumbers and pipefitters unions, 639 were screened in this program. Screening tests indicat...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700130205
更新日期:1988-01-01 00:00:00
abstract::The etiology of retroperitoneal fibrosis is unknown in 70% of the cases. The aim of our study was to examine the possible association between occupational asbestos exposure and retroperitoneal fibrosis; only two cases have been reported in the literature. We gathered all the cases of retroperitoneal fibrosis diagnosed...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/(sici)1097-0274(199804)33:4<418::aid-ajim1
更新日期:1998-04-01 00:00:00
abstract::Computerized hospital discharge diagnoses are useful for occupational disease surveillance. One thousand one hundred twenty-six individuals with asbestosis and 268 individuals with silicosis were identified in New Jersey for the four-year period 1979-1982. Computer-generated maps help to dramatize the localization of ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700130209
更新日期:1988-01-01 00:00:00
abstract:BACKGROUND:Self-reported exposure to secondhand smoke (SHS) has been associated with elevated inflammatory markers in adults. The association between SHS indicated by serum cotinine and markers of inflammation has not been investigated in adult workers. METHODS:Using the subpopulation of employed participants (20 year...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20591
更新日期:2008-08-01 00:00:00