Abstract:
:There is little known about the incidence of cancer among sewage workers. In this paper we examine findings from a retrospective cohort study of 487 white male sewer authority workers employed between January 1950 and October 1979. Vital status was ascertained for 93% of the cohort yielding a total of 6,886 person years. Total mortality from all causes was comparable to that of the general white male U.S. population (Standardized Mortality Ratio [SMR] = 0.91, 95% Confidence Interval [CI] = 0.77-1.07). The cohort was subdivided into those not exposed, and sewer workers who were exposed to sewage effluent, sludge, or wastewater containing chemicals including potential carcinogens. Among the nonexposed group, mortality from all causes was significantly low (SMR = 0.55, 95% CI = 0.33-0.88). Among the exposed sewer workers, mortality from all causes was not significantly different from that of the general white male U.S. population (SMR = 1.00, 95% CI = 0.84-1.19). Mortality from all cancers among exposed sewer workers was slightly higher than that of the general population (SMR = 1.19, 95% CI = 0.79-1.7). Statistically significant elevated mortality ratios were seen for cancer of the larynx (SMR = 7.93, 95% CI = 1.59-23.96), and cancer of the liver (SMR = 5.4, 95% CI = 1.10-16.05). Careful study of the medical and occupational histories of these cases suggested that larynx cancer was possibly work-related, while liver cancer was not. A group estimated to be the highest exposed, composed predominantly of operatives, had a higher directly adjusted death rate from all malignant neoplasms combined compared to all other workers (rate ratio = 1.64). These findings of increased risk of cancer among exposed sewage workers, especially operators, are based on small number of cases and should be interpreted with caution. Studies of larger cohorts are needed to clarify the risk of these cancers among sewage workers.
journal_name
Am J Ind Medjournal_title
American journal of industrial medicineauthors
Lafleur J,Vena JEdoi
10.1002/ajim.4700190110subject
Has Abstractpub_date
1991-01-01 00:00:00pages
75-86issue
1eissn
0271-3586issn
1097-0274journal_volume
19pub_type
杂志文章abstract:OBJECTIVE:The objective of this study was to examine the association between Dupuytren's contracture (DC), repetitive handwork (RHW), heavy handwork (HHW), and/or vibration exposure. METHODS:Frequency and intensity of the three types of handwork were collected and compared between DC patients and controls. Hours of wo...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22736
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND:The purpose of this study was to evaluate cancer incidence in the membership a largely Hispanic farmworker labor union in California, the United Farmworkers of America (UFW) and to examine cancer-site specific distributions as well as histology and stage of cancer at diagnosis in this group. METHODS:An elec...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.1125
更新日期:2001-11-01 00:00:00
abstract:BACKGROUND:The purpose of the study was to evaluate trends in occupational lead exposures throughout U.S. industry after the establishment of the general industry lead standard in 1978 and the construction industry standard in 1993. METHODS:Lead exposure measurements collected by the Occupational Safety and Health Adm...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20008
更新日期:2004-06-01 00:00:00
abstract:METHODS:We used a population-based sample of 403 Parkinson's disease cases and 405 controls to examine risks by occupation. Results were compared to a previous clinic-based analysis. RESULTS:With censoring of jobs held within 10 years of diagnosis, the following had significantly or strongly increased risks: social sc...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22272
更新日期:2014-02-01 00:00:00
abstract::A study of 67 subjects in a small titanium oxide paint factory in Nigeria showed 50-54% frequency for airway symptoms, 20-40% for neurological symptoms, and 10-27% for other symptoms. The symptoms were well correlated with exposure (p less than .05) and pulmonary function tests (PFTs). The directly exposed subjects ha...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700120206
更新日期:1987-01-01 00:00:00
abstract:BACKGROUND:Evidence regarding the unequal burden of occupational injuries between workers employed by temporary agencies and those in standard employment arrangements is unclear. Studies range from no significant differences in risk to substantial increased risk for temporary workers. The purpose of this study is to co...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20728
更新日期:2010-02-01 00:00:00
abstract::Potential exposures to extremely low frequency (ELF) magnetic fields were investigated in response to worker concerns about an apparent increased spontaneous abortion risk in a payroll office environment. Concern in this office centered on the use of video display terminals (VDTs), which have been investigated as a po...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700250204
更新日期:1994-02-01 00:00:00
abstract::A death certificate based case-control study of lung cancer in two Ontario cities was performed to estimate the risk of lung cancer attributable to occupation in Ontario, and to estimate the proportion of occupational lung cancers receiving compensation from the Workers' Compensation Board. Occupation and industry wer...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700270112
更新日期:1995-01-01 00:00:00
abstract:BACKGROUND:Cigarette smoke and asbestos are recognized causes of lung carcinoma and together promote carcinogenesis. Adenocarcinoma is currently the most common cause of lung cancer in the USA and it has been linked to both smoking and asbestos exposure. Mutations in the epidermal growth factor gene receptor (EGFR) occ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22691
更新日期:2017-03-01 00:00:00
abstract::In 15 random autopsies, nickel (Ni) and chromium (Cr) were determined quantitatively by atomic absorption spectrometry (AAS) in human lung tissue to evaluate norm values. None of the deceased persons had had an occupational exposure to Cr or Ni or their compounds. In all, 22 tissue samples were taken from each lung at...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700120107
更新日期:1987-01-01 00:00:00
abstract:BACKGROUND:Pulmonary tuberculosis and HIV incidence, mortality, and the progression of silicosis and lung function impairment are described over a 1-year period in migrant ex-gold miners from Lesotho. METHODS:Seven hundred seventy-nine Basotho miners were followed for 1 year starting 18 months after lay-off from a Sou...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20767
更新日期:2009-12-01 00:00:00
abstract:BACKGROUND:The purpose of this study was to investigate the prevalence of airway hyperresponsiveness induced by methylene diphenyldiisocyanate (MDI) and toluene diisocyanate (TDI) at a petrochemical industry complex in Korea. METHODS:Questionnaires, allergic skin test, and nonspecific airway hyperresponsiveness (AHR) ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/(sici)1097-0274(200006)37:6<663::aid-ajim1
更新日期:2000-06-01 00:00:00
abstract::Limitations on the use of full halogenated chlorofluorocarbons (CFCs) may create occupational environmental problems. These are currently largely unknown, because the toxicology of most CFC substitutes is unknown. Therefore, toxicity testing of CFC substitutes is necessary, and this can best be done before their use c...
journal_title:American journal of industrial medicine
pub_type: 杂志文章,评审
doi:10.1002/ajim.4700190615
更新日期:1991-01-01 00:00:00
abstract::Conventional occupational mortality analysis, using underlying cause of death coding, underestimates the contribution of those chronic diseases which are mentioned on the death certificate but which usually do not appear as underlying cause of death. Proportionate occupational mortality analysis, using all the mention...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700140311
更新日期:1988-01-01 00:00:00
abstract:BACKGROUND:This study explored economic consequences of work-related injuries using a longitudinal data source. METHODS:Data were from the National Longitudinal Survey of Youth, 1979 cohort (n = 12,686). Short-term consequences were measured when the injury was reported. "Difference-in-differences" approach was applie...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22559
更新日期:2016-02-01 00:00:00
abstract:BACKGROUND:The Mine Safety and Health Administration (MSHA) proposes to issue citations for non-compliance with the exposure limit for respirable coal mine dust when measured exposure exceeds the exposure limit with a "high degree of confidence." This criterion threshold value (CTV) is derived from the sampling and ana...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20318
更新日期:2006-06-01 00:00:00
abstract:BACKGROUND:Radiographic shadows of coal workers' pneumoconiosis (CWP) are commonly described as predominantly in the upper lung zones. METHODS:We evaluated the lung distribution of small opacities on surveillance chest radiographs (CXRs) taken between 1981 and 2010 among 2,467 underground US coal miners. All had evide...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22049
更新日期:2012-09-01 00:00:00
abstract::The use and maintenance of firearms is a common and often preventable source of adult lead exposure that is often poorly understood by medical professionals. This case describes an elevated blood lead level (BLL) in an adult man due to the exposure sources of ammunition reloading and indoor target shooting in the base...
journal_title:American journal of industrial medicine
pub_type:
doi:10.1002/ajim.23119
更新日期:2020-08-01 00:00:00
abstract:BACKGROUND:Persistent and growing occupation-based disparities related to tobacco pose a serious public health challenge. Tobacco exacts a disproportionate toll on individuals employed in working class occupations, due to higher prevalence of smoking and exposure to secondhand smoke among these workers compared to othe...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20026
更新日期:2004-08-01 00:00:00
abstract::Data were collected on 228 consecutive back injuries in Boston's General Mail Facility and 228 non-injured controls drawn randomly from each case's work unit, matching on craft (clerk, mailhandler, maintenance), shift, and general supervisor. Data were collected on age, gender, duration of employment, 3 year history o...
journal_title:American journal of industrial medicine
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1002/ajim.4700200406
更新日期:1991-01-01 00:00:00
abstract:BACKGROUND:Rates of musculoskeletal disorders in construction remain high. Few studies have described barriers and facilitators to the use of available ergonomic solutions. This paper describes these barriers and facilitators and their relationship to the level of adoption. METHODS:Three analysts rated 16 proposed erg...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22693
更新日期:2017-03-01 00:00:00
abstract:BACKGROUND:Mineral dusts that contain crystalline silica have been associated directly or indirectly with the development of pneumoconiosis or silicosis, non-malignant respiratory diseases, lung cancer, and other diseases. The health impacts on workers with silica mixed dust exposure in tin mines and dose-response rela...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20248
更新日期:2006-02-01 00:00:00
abstract:BACKGROUND:Construction is a hazardous occupation, with Latino (Hispanic) workers at a greater risk for death than other ethnicities/races. Latinos accounted for over half of construction injuries involving days away from work in Nevada in 2006. METHODS:This study recruited 30 Latino construction workers from three So...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20735
更新日期:2010-02-01 00:00:00
abstract:BACKGROUND:Home healthcare workers (HHWs) provide medical and nonmedical services to home-bound patients. They are at great risk of experiencing violence perpetrated by patients (type II violence). Establishing the reliable prevalence of such violence and identifying vulnerable subgroups are essential in enhancing HHWs...
journal_title:American journal of industrial medicine
pub_type: 杂志文章,评审
doi:10.1002/ajim.23095
更新日期:2020-05-01 00:00:00
abstract::Eight healthy volunteers were exposed to purified lipopolysaccharide (LPS) by controlled inhalation. Bronchoalveolar lavage (BAL) 3 hours after exposure revealed a pronounced neutrophilia, increase in lymphocytes, fibronectin concentration, and decrease in alveolar macrophage phagocytosis, as compared to a reference B...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700250127
更新日期:1994-01-01 00:00:00
abstract:BACKGROUND:Occupational bladder cancer mortality among minority racial/ethnic groups is not well described compared to occupational bladder cancer mortality among non-minority males in the United States. METHODS:Race/ethnicity- and sex-specific bladder cancer mortality (1985-1992) of workers employed in 21 states was ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/1097-0274(200007)38:1<90::aid-ajim10>3.0.c
更新日期:2000-07-01 00:00:00
abstract:BACKGROUND:The Limulus amebocyte lysate (LAL) assay may underestimate endotoxins because only soluble endotoxins are determined. The solubility of endotoxins was, therefore, studied in two species of Gram-negative bacteria. METHODS:Cultures were grown in serum broth, cells were harvested by centrifugation and washed i...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20089
更新日期:2004-10-01 00:00:00
abstract::Silica is not generally considered to be a carcinogen, however, occupations characterized by high exposure to crystalline silica have excessive rates of lung cancer mortality. Respiratory cancer excesses have been reported from North America and from Europe for the following dusty trades in which exposure to silica is...
journal_title:American journal of industrial medicine
pub_type: 杂志文章,评审
doi:10.1002/ajim.4700030408
更新日期:1982-01-01 00:00:00
abstract::Both subcutaneous and hepatic hemangiosarcomas were induced in mice exposed to vinyl chloride monomer, and for the first time, the ultrastructure of hemangiosarcomas related to vinyl chloride exposure has been described. The subcutaneous hemangiosarcoma developed in a mouse's ear 29 weeks after exposure to 10 ppm viny...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700020205
更新日期:1981-01-01 00:00:00
abstract:BACKGROUND:A major French chlorine chemical plant (chlor-alkali process with diaphragm cell and manufacturing of organochlorine chemicals) has used or produced known or suspected carcinogenic compounds. METHODS:A cohort study, based on the plant occupational health service and the regional cancer registry, analyzed th...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22069
更新日期:2012-09-01 00:00:00