Abstract:
:Silica is not generally considered to be a carcinogen, however, occupations characterized by high exposure to crystalline silica have excessive rates of lung cancer mortality. Respiratory cancer excesses have been reported from North America and from Europe for the following dusty trades in which exposure to silica is a common factor: iron and steel foundry workers, steel casting workers, sand blasters, metal molders, non-uranium miners, and ceramic workers. These findings have been reinforced by two reports from the Swedish Pneumoconiosis Register and the Ontario Ministry of Labor indicating that silicotics have statistically significant risks of lung cancer mortality. Animal studies suggest that silica can be an initiating carcinogen or can act as a cocarcinogen or promoter when combined with benzo(a)pyrene. We propose three candidate hypotheses and two pathways for silicocarcinogenesis.
journal_name
Am J Ind Medjournal_title
American journal of industrial medicineauthors
Goldsmith DF,Guidotti TL,Johnston DRdoi
10.1002/ajim.4700030408subject
Has Abstractpub_date
1982-01-01 00:00:00pages
423-40issue
4eissn
0271-3586issn
1097-0274journal_volume
3pub_type
杂志文章,评审abstract::Cohort mortality and nested case-control studies were conducted involving 2,901 men employed 1 year or more between 1940 and 1986 at any of four California facilities of a major chemical company. Employees experienced fewer deaths from each of the major causes than were expected based on U.S., California, and local co...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700220107
更新日期:1992-01-01 00:00:00
abstract::Assessing the health risks of complex mixtures of polynuclear aromatic hydrocarbons such as diesel fumes and asphalt or bitumen continues to be a major challenge for occupational and environmental health scientists. The special Asphalt issue of the American Journal of Industrial Medicine (Cancer Mortality Among Europe...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.10215
更新日期:2003-03-01 00:00:00
abstract:BACKGROUND:Thoroughbred horse farm workers self-report a high frequency of work-related injuries and pain. However, an analysis of Thoroughbred horse farm workers' compensation injury claims is absent from the literature, yet may benefit worker safety. METHODS:We analyzed workers' compensation insurance firm data cont...
journal_title:American journal of industrial medicine
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doi:10.1002/ajim.23159
更新日期:2020-10-01 00:00:00
abstract:BACKGROUND:Climate change is a natural phenomenon that has been intensified due to increased emissions of greenhouse gases (GHG). It has become an indispensable issue in international negotiations related to global sustainability and is deeply related to the overall status of environmental health in our planet. METHOD...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22051
更新日期:2012-12-01 00:00:00
abstract:BACKGROUND:Field-portable instruments can offer expeditious analytical results to health professionals in field settings and in areas lacking laboratory infrastructure. This study further evaluated an electroanalytical field-portable instrument, which rapidly analyzes blood lead concentrations. METHODS:A portable anod...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20096
更新日期:2004-12-01 00:00:00
abstract::This study examined mortality to December 31, 1989 in a cohort of 2,222 males employed between 1947 and 1975 at a transformer manufacturing plant in Canada, where there had been extensive use of transformer fluid, some containing polychlorinated biphenyls (PCBs). A combined cohort list of 2,222 names was independently...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700250310
更新日期:1994-03-01 00:00:00
abstract:BACKGROUND:Migrant and seasonal farmworkers are at risk for occupational illnesses from pesticide exposure, and the effectiveness of pesticide safety regulations has not been evaluated. It is important to learn from farmworker safety experiences to develop effective measures to improve agricultural workplace safety. M...
journal_title:American journal of industrial medicine
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更新日期:2001-05-01 00:00:00
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更新日期:2000-11-01 00:00:00
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journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20026
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doi:10.1002/ajim.20661
更新日期:2009-03-01 00:00:00
abstract::The association between lead absorption and objective psychological performance tests in five groups with different levels of lead absorption was studied in the following groups: (1) a control, non-lead-exposed group; (2) cable splicers, (3) cable manufactures, and (4) secondary lead smelter workers. The following per...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700010320
更新日期:1980-01-01 00:00:00
abstract:BACKGROUND:A series of illnesses occurred in Earlimart, CA on November 13, 1999 following a metam-sodium sprinkler application to a potato field on the southern edge of the town. METHODS:Case information was obtained from direct interviews, from illness complaints filed with state or county agencies, or from illness r...
journal_title:American journal of industrial medicine
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doi:10.1002/ajim.20037
更新日期:2004-07-01 00:00:00
abstract:BACKGROUND:Rates of occupational injury among immigrant workers are widely believed to be underestimated. The goal of this study was to enhance understanding of the burden of occupational injury and the work organization factors underlying injury among immigrant Latino residential construction workers. METHODS:Prospec...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22014
更新日期:2012-08-01 00:00:00
abstract::Animal studies show that antimony may cause lung cancer and heart and lung disease in rodents. In exposed humans, ECG abnormalities and heart and lung disease have been reported. This mortality study of 1,014 men employed between 1937 and 1971 in a Texas antimony smelter consisted primarily of workers of Spanish ances...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700270510
更新日期:1995-05-01 00:00:00
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journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20503
更新日期:2007-09-01 00:00:00
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journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700200306
更新日期:1991-01-01 00:00:00
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journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22537
更新日期:2016-01-01 00:00:00
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journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/(SICI)1097-0274(199608)30:2<202::AID-AJIM1
更新日期:1996-08-01 00:00:00
abstract:BACKGROUND:Exposure to chemicals in polluted soil was studied during the remediation of four polluted sites. They are sawmill areas contaminated with chlorophenols and polychlorinated dibenzo-p-dioxins and furanes (PCDD/F), wood impregnating plants contaminated with polycyclic aromatic hydrocarbons (PAH) from creosote ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.1031
更新日期:2001-04-01 00:00:00
abstract::To elucidate the effect of low level lead (Pb) exposure on somatic and autonomic peripheral nerve functions in ceramic painters, 58 males and 70 females, aged 29-75 years (mean 53.3 years), with lead concentrations in blood (Pb-B) ranging from 2.1 to 69.5 micrograms/dl (geometric mean 13.3 micrograms/dl), were examine...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
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更新日期:1996-05-01 00:00:00
abstract::To study whether low-level exposure to asbestos contributes to lung cancer risk, the asbestos body (AB) content in lung tissue was measured in 476 patients with lung cancer and 369 patients with other diseases, all from a Japanese industrialized city. Eleven patients with histologically confirmed asbestosis were inclu...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700180505
更新日期:1990-01-01 00:00:00
abstract:BACKGROUND:Pulmonary tuberculosis and HIV incidence, mortality, and the progression of silicosis and lung function impairment are described over a 1-year period in migrant ex-gold miners from Lesotho. METHODS:Seven hundred seventy-nine Basotho miners were followed for 1 year starting 18 months after lay-off from a Sou...
journal_title:American journal of industrial medicine
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doi:10.1002/ajim.20767
更新日期:2009-12-01 00:00:00
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journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700210208
更新日期:1992-01-01 00:00:00
abstract:BACKGROUND:Occupational health problems among home-helpers have been reported in a series of studies, and the need for intervention has been pointed out. To facilitate decisions regarding interventions and to establish baseline values for future evaluation of preventive efforts, the present study aimed to elucidate the...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.10028
更新日期:2002-01-01 00:00:00
abstract:BACKGROUND:This study examines the prevalence of physician-diagnosed respiratory conditions and mental health symptoms in firefighters and emergency medical service workers up to 9 years after rescue/recovery efforts at the World Trade Center (WTC). METHODS:We analyzed Fire Department of New York (FDNY) physician and ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20993
更新日期:2011-09-01 00:00:00
abstract:BACKGROUND:Despite their legal rights, individuals with disabilities face numerous obstacles to integration in the workplace which can result in their discharge from the labor force. Currently occupational physicians have few resources to help decide whether to integrate disabled workers in pre-placement, or in cases o...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22818
更新日期:2018-04-01 00:00:00
abstract::Investigators must often rely on self-reported work history information collected with questionnaires. However, little is known about the agreement between self-reported estimates of exposure and records kept by companies. As part of a cross-sectional medical study of structural fumigation workers, self-reported work ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/(sici)1097-0274(199710)32:4<364::aid-ajim7
更新日期:1997-10-01 00:00:00
abstract:CONTEXT:A definite cause of sarcoidosis has not been identified, however past research suggests that environmental factors may be triggers of the granulomatous response in genetically susceptible individuals. CASE PRESENTATION:A 22-year-old male non-smoker, presented with progressive exertional dyspnea and cough of 3 ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.21030
更新日期:2012-04-01 00:00:00
abstract:BACKGROUND:Job-exposure matrices (JEM) are used for exposure assessment in occupational studies, but they can involve errors. We assessed agreement between the Nordic Occupational Cancer Studies JEM (NOCCA-JEM) and aggregate and individual dose estimates for cosmic radiation exposure among Finnish airline personnel. M...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22705
更新日期:2017-04-01 00:00:00
abstract:OBJECTIVES:To assess changes in work characteristics, socioeconomic status inequalities in changes in work characteristics, and whether US workplaces are becoming more stressful. METHODS:We analyzed data from 5361 employed participants from the 2002, 2006, 2010, and 2014 NIOSH Quality of Work Life Surveys, based on re...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22971
更新日期:2019-06-01 00:00:00