Abstract：
:Both subcutaneous and hepatic hemangiosarcomas were induced in mice exposed to vinyl chloride monomer, and for the first time, the ultrastructure of hemangiosarcomas related to vinyl chloride exposure has been described. The subcutaneous hemangiosarcoma developed in a mouse's ear 29 weeks after exposure to 10 ppm vinyl chloride for 4 weeks, and the hepatic hemangiosarcoma was found in a mouse's liver at necropsy 56 weeks after exposure to 600 ppm vinyl chloride for 4 weeks. Both tumors showed a localized, cystic nodular appearance with a dark red tone. Histologically, an angiomatous architecture, the presence of neoplastic mesenchymal cell aggregates, focal necrosis, and hemorrhagic foci were common. Ultrastructurally, two neoplastic cell types, a mesenchymal and a well-differentiated endothelial cell type, were identified in both tumors. In addition, in the hepatic tumor, a pericyte-like neoplastic cell was also present. The incidence of hemangiosarcoma was much lower than that of lung tumors (alveologenic tumor) in mice exposed to vinyl chloride at the same concentrations for the same duration. This study suggests that there is no basic difference in ultrastructure between the vinyl chloride-induced hemangiosarcomas and hemangiosarcomas not related to this chemical exposure.
journal_name
Am J Ind Medjournal_title
American journal of industrial medicineauthors
Suzuki Ydoi
10.1002/ajim.4700020205subject
Has Abstractpub_date
1981-01-01 00:00:00pages
103-17issue
2eissn
0271-3586issn
1097-0274journal_volume
2pub_type
杂志文章abstract：BACKGROUND:We sought to gain insight into workers' knowledge, beliefs, and attitudes on the subject of testing for genetic susceptibility to beryllium. METHODS:Five focus groups were held with 30 current and former beryllium workers and nine family members. Audio recordings were transcribed and assessed by hierarchica...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.20962
更新日期：2011-07-01 00:00:00
abstract：BACKGROUND:There is growing evidence that exposure to organic solvents can play a role in the etiology of rheumatoid arthritis (RA). This prospective cohort study aimed to investigate the association between RA and toluene exposure. METHODS:The study cohort consisted of Korea Occupational Safety and Health Agency data...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.23226
更新日期：2021-01-29 00:00:00
abstract：BACKGROUND:Rates of occupational injury among immigrant workers are widely believed to be underestimated. The goal of this study was to enhance understanding of the burden of occupational injury and the work organization factors underlying injury among immigrant Latino residential construction workers. METHODS:Prospec...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.22014
更新日期：2012-08-01 00:00:00
abstract：BACKGROUND:This study documented the burden of nonfatal construction industry work-related injuries treated in hospital emergency departments in the United States (US) from 1998 through 2005 and described injured worker demographics and injury characteristics. METHODS:Data from the National Electronic Injury Surveilla...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.20829
更新日期：2010-06-01 00:00:00
abstract：BACKGROUND:The SARS outbreak in 2003 has spawned a major controversy concerning protective performance facemasks for healthcare workers. This study reports a study on in-vivo protective performance of surgical masks and N95 respirators. METHODS:Typical surgical masks and N95 respirators used in Hong Kong hospitals wer...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.20395
更新日期：2006-12-01 00:00:00
abstract：:Exposure to grain dust has been associated with a neutrophilic bronchitis. In vitro studies suggest several possible mechanisms for recruitment of neutrophils, including direct chemotaxis to aqueous grain dust extracts and release of chemotactic activity by bronchial epithelial cells in response to challenge with grai...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.4700250122
更新日期：1994-01-01 00:00:00
abstract：BACKGROUND:In studies in men, risk estimates on occupation and bladder cancer are distorted by about 10% when not adjusting for smoking. We examined the degree to which occupational risk estimates for bladder cancer in women are confounded by smoking, and the degree of residual confounding by inadequate control of this...
journal_title：American journal of industrial medicine
pub_type： 杂志文章,meta分析
doi：10.1002/(sici)1097-0274(199907)36:1<75::aid-ajim11
更新日期：1999-07-01 00:00:00
abstract：INTRODUCTION:Noise exposure has long been an occupational health concern and has been an important area of focus of the Occupational Safety and Health Administration (OSHA) since its founding. Nevertheless, it remains unclear what effects OSHA's noise standards have had on employer efforts to reduce risks. Consequently...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.23116
更新日期：2020-07-01 00:00:00
abstract：INTRODUCTION:Occupational health researchers can play a pivotal role in increasing our understanding of the role of physical and psychosocial working conditions in producing socioeconomic health disparities and trends of increasing socioeconomic health disparities, contributing to interventions to reduce such dispariti...
journal_title：American journal of industrial medicine
pub_type： 社论,评审
doi：10.1002/ajim.20766
更新日期：2010-02-01 00:00:00
abstract：BACKGROUND:Workers in the Agriculture, Forestry, and Fisheries (AgFF) sector experience exposures directly related to the work itself, as well as the physical environment in which the work occurs. Health outcomes vary from immediate to delayed, and from acute to chronic. METHODS:We reviewed existing literature on the ...
journal_title：American journal of industrial medicine
pub_type： 杂志文章,评审
doi：10.1002/ajim.22170
更新日期：2013-08-01 00:00:00
abstract：:We conducted a comparative study of pulmonary dysfunction among workers who were exposed to silica, asbestos, or coalmine dust. The results showed that all three groups of dust-exposed workers, even those without radiographic signs of pneumoconiosis, had decreased spirometric parameters and diffusing capacity (DLco) i...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/(sici)1097-0274(199705)31:5<495::aid-ajim2
更新日期：1997-05-01 00:00:00
abstract：:This commentary challenges a recently published perception that Dr. Le Roy Upson Gardner had not actually discovered in 1942 that inhaled chrysotile fibers could induce malignant neoplasia in mice. The handwritten laboratory notes and some of Dr. Gardner's slides have recently been found. They verify that the tumors h...
journal_title：American journal of industrial medicine
pub_type： 传,历史文章,杂志文章
doi：10.1002/ajim.4700270413
更新日期：1995-04-01 00:00:00
abstract：BACKGROUND:Job-exposure matrices (JEM) are used for exposure assessment in occupational studies, but they can involve errors. We assessed agreement between the Nordic Occupational Cancer Studies JEM (NOCCA-JEM) and aggregate and individual dose estimates for cosmic radiation exposure among Finnish airline personnel. M...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.22705
更新日期：2017-04-01 00:00:00
abstract：OBJECTIVES:To examine disparities between job control scores in Black and White subjects and attempt to discern whether self-rated low job control in Blacks may arise from structural segregation into different jobs, or represents individual responses to race-based discrimination in hiring or promotion. METHODS:Data fr...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.22255
更新日期：2014-05-01 00:00:00
abstract：BACKGROUND:The aim of this study was to investigate whether job strain had an effect on the risk of occupational injury of workers at small- to medium-sized manufacturing companies. METHODS:We conducted a prospective follow-up survey and finally 1,209 workers in South Korea were included in this study. At time X1, we ...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.20673
更新日期：2009-04-01 00:00:00
abstract：:This report describes the reanalysis of a cross-sectional study of asthma in a large cohort of autoworkers with exposure to metalworking fluids (MWF). There is strong evidence from case reports, clinical studies, and medical surveillance data that exposure to MWF can cause asthma, yet no association was found in the o...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/(sici)1097-0274(199706)31:6<671::aid-ajim1
更新日期：1997-06-01 00:00:00
abstract：:In the past 10 years there has been growing awareness among occupational health professionals worldwide of the large burden of illness associated with musculoskeletal disorders of the neck and upper limbs. It has been suggested that these disorders are associated with highly repetitive work and are due, at least in pa...
journal_title：American journal of industrial medicine
pub_type： 杂志文章,meta分析
doi：10.1002/ajim.4700190111
更新日期：1991-01-01 00:00:00
abstract：BACKGROUND:The occupational lung cancer risk in manufacturing and repair of shoes was studied by pooling of two major case-control studies from Germany. METHODS:Some 4184 incident hospital-based cases of primary lung cancer and 4253 population controls, matched for sex, age, and region of residence were intensively in...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/(sici)1097-0274(200006)37:6<575::aid-ajim1
更新日期：2000-06-01 00:00:00
abstract：BACKGROUND:Lead stabilizers (e.g., lead sulfate, lead stearate) are common additives in plastics used in electrical devices. In 1997, three plastics compounders at one California company were severely lead-poisoned. METHODS:The poisonings were investigated by interviewing the workers, employer, and treating physician ...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.20123
更新日期：2005-02-01 00:00:00
abstract：BACKGROUND:A beryllium materials manufacturer is conducting a limited pilot program that offers testing for HLA-DP beta 1E69 with genetic counseling through a third party to applicants for employment. An important consideration in this regard is the prevalence of this marker in the general population, and its consequen...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.10072
更新日期：2002-06-01 00:00:00
abstract：BACKGROUND:Standardized proportionate mortality ratio (SPMR) was found to be 2.2 (95% CI = 1.3-3.5) for esophageal cancer (EC) among workers exposed to refractory brick dust in a large iron-steel complex in China. METHODS:A nested case-control design within a cohort of industrial workers. One hundred and twenty-five E...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/(sici)1097-0274(199903)35:3<272::aid-ajim7
更新日期：1999-03-01 00:00:00
abstract：:The cause-specific mortality (1940-1993) of 2,985 male workers employed in three oil refineries was examined using a proportionate mortality study design. Separate analyses were undertaken by race, refinery, employment status (active and retired), and time since entry into the Oil, Chemical, and Atomic Workers (OCAW) ...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/(sici)1097-0274(199804)33:4<327::aid-ajim3
更新日期：1998-04-01 00:00:00
abstract：OBJECTIVE:Longitudinal assessment of lower respiratory symptoms (LRS) in community members with World Trade Center (WTC) exposures. METHODS:Adult members of a treatment program with complete standardized visits were evaluated (n = 798). Association of demographic characteristics, mental health symptoms and lung functi...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.22642
更新日期：2016-09-01 00:00:00
abstract：BACKGROUND:The etiologic role of biomechanical factors for low back injury (LBI) needs to be confirmed in prospective studies that control for psychosocial factors. METHODS:Complete baseline information on 1,233 vehicle operators was gathered during medical examinations and by questionnaire. First LBI during 7.5 years...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.20094
更新日期：2004-12-01 00:00:00
abstract：BACKGROUND:Mortality rates associated with total pneumoconiosis, including coal worker's pneumoconiosis (CWP), have remained elevated. METHODS:2003-2013 pneumoconiosis mortality data obtained from National Center for Health Statistics and 2011-2013 Kentucky death certificates were analyzed. RESULTS:Total pneumoconios...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.22511
更新日期：2015-10-01 00:00:00
abstract：BACKGROUND:Exposure in the dental environment can increase the risk of respiratory disease in dental healthcare workers (HCWs). This study investigated the prevalence of asthma phenotypes in dental HCWs and associated risk factors. METHODS:A cross-sectional study of 454 dental HCWs in five dental institutions in South...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.22041
更新日期：2013-01-01 00:00:00
abstract：BACKGROUND:Because of the rarity of peritoneal mesothelioma, occupational risks associated with it have seldom been studied, particularly among women. In this respect, death certificates databases may provide numbers large enough for analysis, although the International Classification of Diseases, 9th revision (ICD-9) ...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/(sici)1097-0274(199901)35:1<9::aid-ajim2>3
更新日期：1999-01-01 00:00:00
abstract：BACKGROUND:Autopsied lungs from 29 hard rock miners were investigated to determine the relationship of the dust content to pathology, radiology, and occupational exposure. METHODS:Each lung was divided horizontally into three sections. Pathological and radiological studies and chemical analyses were carried out on sam...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.20589
更新日期：2008-07-01 00:00:00
abstract：BACKGROUND:Wastewater treatment workers can be exposed to biological and chemical agents resulting in work-related health effects. The aim of this study was to investigate work-related symptoms in these workers. METHODS:Questionnaire data of 468 employees from 67 sewage treatment plants is evaluated. Personal endotoxi...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.20176
更新日期：2005-07-01 00:00:00
abstract：BACKGROUND:The US military is a large, well-defined occupational cohort offering tremendous opportunities to study risk factors for important health outcomes. This article describes our nested case-control methods to evaluate risk factors for fatal motor vehicle crashes (MVC) within all Service branches in a 1991 Gulf ...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.20190
更新日期：2005-08-01 00:00:00
