Asbestos exposure: a potential cause of retroperitoneal fibrosis.

Abstract:

:The etiology of retroperitoneal fibrosis is unknown in 70% of the cases. The aim of our study was to examine the possible association between occupational asbestos exposure and retroperitoneal fibrosis; only two cases have been reported in the literature. We gathered all the cases of retroperitoneal fibrosis diagnosed in the Tampere University Hospital between 1987 and 1995. We examined their hospital records to evaluate the possible etiology of the disease. We also sent a structured questionnaire to all living patients (10/13) to obtain information on their asbestos exposure. The chest radiographs of the patients were re-read to evaluate possible changes resulting from asbestos exposure. We found 13 cases of idiopathic retroperitoneal fibrosis. Seven patients (all male) had been exposed to asbestos in the past. The chest radiographs of the four most-exposed patients showed characteristic asbestos-related abnormalities, including bilateral pleural plaques, round atelectasis and small irregular lung opacities. In our study, we found that asbestos exposure and asbestos-induced changes in the lung and pleura were common among male retroperitoneal fibrosis patients. We suggest that occupational exposure to asbestos may be an important etiological factor for retroperitoneal fibrosis.

journal_name

Am J Ind Med

authors

Sauni R,Oksa P,Järvenpää R,Parker JE,Roto P

doi

10.1002/(sici)1097-0274(199804)33:4<418::aid-ajim1

subject

Has Abstract

pub_date

1998-04-01 00:00:00

pages

418-21

issue

4

eissn

0271-3586

issn

1097-0274

pii

10.1002/(SICI)1097-0274(199804)33:4<418::AID-AJIM1

journal_volume

33

pub_type

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